Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins

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Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200311064
P932PMC publication ID2172074
P698PubMed publication ID15051738
P5875ResearchGate publication ID8648922

P50authorViola OorschotQ45929277
Judith KlumpermanQ45929310
P2093author name stringRichard H Scheller
Andrew A Peden
Cary D Austin
Boris A Hesser
P2860cites workAltered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptorQ22008778
AP-3: an adaptor-like protein complex with ubiquitous expressionQ24315945
Characterization of the adaptor-related protein complex, AP-3Q24321479
Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomesQ24548353
The assembly of AP-3 adaptor complex-containing clathrin-coated vesicles on synthetic liposomesQ24550983
Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the ratQ24644391
In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamellaQ24657613
Peptide-in-groove interactions link target proteins to the beta-propeller of clathrinQ27621166
The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.Q27930544
Association of the AP-3 adaptor complex with clathrinQ28267691
A function for the AP3 coat complex in synaptic vesicle formation from endosomesQ28567917
A tubular endosomal fraction from rat liver: biochemical evidence of receptor sorting by defaultQ28571126
Syntaxin 6 functions in trans-Golgi network vesicle traffickingQ28572919
The AP-3 complex: a coat of many coloursQ28593713
The biogenesis of lysosomesQ29617860
mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptorsQ29622880
Biosynthetic transport of a major lysosome-associated membrane glycoprotein 2, lamp-2: a significant fraction of newly synthesized lamp-2 is delivered to lysosomes by way of early endosomesQ30426316
Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cellsQ30476964
Morphology and dynamics of clathrin/GGA1-coated carriers budding from the trans-Golgi networkQ30477740
Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomesQ31048369
A dileucine-like sorting signal directs transport into an AP-3-dependent, clathrin-independent pathway to the yeast vacuoleQ33888752
Targeting of lysosomal proteins.Q33975549
The delta subunit of AP-3 is required for efficient transport of VSV-G from the trans-Golgi network to the cell surfaceQ34067421
Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi networkQ34148158
Adaptor-related proteinsQ34309059
The molecular machinery for the biogenesis of lysosome-related organelles: lessons from Hermansky-Pudlak syndromeQ34874723
Three-dimensional structure of endosomes in BHK-21 cellsQ35602540
Deep-etch visualization of proteins involved in clathrin assemblyQ36219469
A quantitative analysis of the endocytic pathway in baby hamster kidney cellsQ36222043
Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosomeQ36222118
Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalizationQ36222540
Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow processQ36232964
The yeast adaptor protein complex, AP-3, is essential for the efficient delivery of alkaline phosphatase by the alternate pathway to the vacuoleQ36255062
Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transportQ36255884
Assembly and function of AP-3 complexes in cells expressing mutant subunits.Q36381130
Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membraneQ36531261
pH and the recycling of transferrin during receptor-mediated endocytosisQ37609089
Binding of apotransferrin to K562 cells: explanation of the transferrin cycleQ37609108
The mammalian AP-3 adaptor-like complex mediates the intracellular transport of lysosomal membrane glycoproteins.Q38331973
Dynamin-dependent transferrin receptor recycling by endosome-derived clathrin-coated vesiclesQ39354587
AP-1A and AP-3A lysosomal sorting functionsQ40704343
Controlled elimination of clathrin heavy-chain expression in DT40 lymphocytes.Q40707676
Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells.Q40727441
Biogenesis of lysosomal membranesQ40764053
Intracellular trafficking of lysosomal membrane proteins.Q40992161
Improving structural integrity of cryosections for immunogold labelingQ41153038
A novel adaptor-related protein complexQ41202077
Possible pathways for lysosomal enzyme deliveryQ41494255
Targeting and mistargeting of plasma membrane adaptors in vitroQ41511613
Sorting of endocytosed transferrin and asialoglycoprotein occurs immediately after internalization in HepG2 cellsQ41517247
Differences in the endosomal distributions of the two mannose 6-phosphate receptorsQ41551657
Expression of transferrin receptor on murine hematopoietic progenitorsQ41558833
Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: kinetic and morphological analysisQ41913589
Characterization of plasma membrane proteins identified by monoclonal antibodies.Q42827407
Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapseQ47435856
The role of endosomes and lysosomes in MHC class II functioningQ47927773
Biosynthetic transport of a major lysosomal membrane glycoprotein, lamp-1: convergence of biosynthetic and endocytic pathways occurs at three distinctive pointsQ71735769
Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosisQ72545744
Cycling of two endogenous lysosomal membrane proteins, lamp-2 and acid phosphatase, between the cell surface and lysosomes in cultured rat hepatocytesQ72694999
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmembrane proteinQ423042
P304page(s)1065-1076
P577publication date2004-03-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleLocalization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins
P478volume164

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