Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells

scientific article

Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PNAS..107.2556A
P356DOI10.1073/PNAS.0913671107
P932PMC publication ID2823916
P698PubMed publication ID20133794
P5875ResearchGate publication ID41408646

P50authorLinrong LuQ51443677
P2093author name stringMari L Shinohara
Harvey Cantor
Nami McCarty
Roberto A Maldonado
Diana A Alvarez Arias
P2860cites workRab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesisQ24301410
Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins)Q24679697
The immunological synapse: a molecular machine controlling T cell activationQ28139151
miR-181a is an intrinsic modulator of T cell sensitivity and selectionQ28294631
Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytesQ28510733
Retrograde transport from endosomes to the trans-Golgi networkQ29617826
mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptorsQ29622880
Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation.Q30482470
Detailed analysis of gene expression during development of T cell lineages in the thymus.Q33203664
A PCR primer bank for quantitative gene expression analysisQ33447710
Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding siteQ33888654
Positive and negative selection of T cellsQ34157557
Distinct and redundant functions of mu1 medium chains of the AP-1 clathrin-associated protein complex in the nematode Caenorhabditis elegansQ34744594
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choiceQ34831201
The Ras/MAPK cascade and the control of positive selectionQ35076682
Signaling life and death in the thymus: timing is everythingQ35089616
Common principles in clathrin-mediated sorting at the Golgi and the plasma membraneQ36142770
Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.Q36191417
Mice lacking major histocompatibility complex class I and class II moleculesQ36271130
Commitment issues: linking positive selection signals and lineage diversification in the thymusQ36382781
Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cellsQ36401236
Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptorQ40817578
On the dynamics of TCR:CD3 complex cell surface expression and downmodulationQ40837872
The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapseQ41762464
Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.Q42831149
Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulationQ42947974
Imaging synapse formation during thymocyte selection: inability of CD3zeta to form a stable central accumulation during negative selectionQ43968754
Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylationQ44066636
Changing directions: clathrin-mediated transport between the Golgi and endosomesQ44305038
TCR down-regulation controls virus-specific CD8+ T cell responsesQ45388594
Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complexQ46124218
B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapseQ46346021
The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytesQ46647653
Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes.Q47607418
Two distinct pathways exist for down-regulation of the TCR.Q47909827
Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection.Q52209484
Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1.Q53489794
CD69 expression during selection and maturation of CD4+8+ thymocytes.Q54247021
CTLA-4 differentially regulates the immunological synapse in CD4 T cell subsetsQ56901431
Cytolytic T lymphocyte-associated antigen-4 and the TCR zeta/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2Q56906783
Quantitative analysis of the T cell repertoire that escapes negative selectionQ73152040
Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradationQ73925265
Early embryonic death of mice deficient in gamma-adaptinQ74456604
Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cellsQ74638361
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2556-2561
P577publication date2010-01-25
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleUnexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells
P478volume107

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cites work (P2860)
Q91955736Age-related transcriptional modules and TF-miRNA-mRNA interactions in neonatal and infant human thymus
Q92375590Leucine zipper transcription factor-like 1 binds adaptor protein complex-1 and 2 and participates in trafficking of transferrin receptor 1
Q38090984Role of inositol phospholipid signaling in natural killer cell biology.

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