scholarly article | Q13442814 |
P356 | DOI | 10.1016/S1074-7613(00)80120-X |
P698 | PubMed publication ID | 10549627 |
P2093 | author name string | O Kanagawa | |
E R Unanue | |||
D A Peterson | |||
R J DiPaolo | |||
P2860 | cites work | Threshold detection of self-antigen/MHC class II complexes formed in vivo: constitutive presentation of an immunodominant epitope of hen egg lysozyme (HEL) in HEL-transgenic mice | Q70480160 |
Immune responses to self peptides naturally presented by murine class II major histocompatibility complex molecules | Q71405229 | ||
A vector driving the expression of foreign cDNAs in the MHC class II-positive cells of transgenic mice | Q71606864 | ||
An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction | Q72105874 | ||
Dose-dependent T cell tolerance to an immunodominant self peptide | Q72119394 | ||
Positive and negative thymocyte selection induced by different concentrations of a single peptide | Q72293139 | ||
Processing and Presentation of Hen Egg-White Lysozyme by Macrophages | Q72382525 | ||
T Cell Receptor Recognition of MHC Class II–Bound Peptide Flanking Residues Enhances Immunogenicity and Results in Altered TCR V Region Usage | Q73767636 | ||
The minimal number of antigen‐major histocompatibility complex class II complexes required for activation of naive and primed T cells | Q74179334 | ||
Inhibition of thymocyte positive selection by natural MHC: peptide ligands | Q74578783 | ||
An endogenously processed self peptide and the corresponding exogenous peptide bound to the same MHC class II molecule could be distinct ligands for TCR with different kinetic stability | Q77714941 | ||
Autoreactivity of T cells from nonobese diabetic mice: An I-Ag7-dependent reaction | Q32123429 | ||
How some T cells escape tolerance induction | Q34418421 | ||
Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules | Q35958588 | ||
T cell determinant structure: cores and determinant envelopes in three mouse major histocompatibility complex haplotypes | Q36229970 | ||
In vivo and in vitro clonal deletion of double-positive thymocytes | Q36231231 | ||
Mechanisms influencing the immunodominance of T cell determinants | Q36355734 | ||
The inability to process a self-peptide allows autoreactive T cells to escape tolerance | Q36361234 | ||
Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells. | Q36363106 | ||
Exogenously Provided Peptides of a Self-antigen Can Be Processed into Forms that Are Recognized by Self–T Cells | Q36400766 | ||
Endogenous Myelin Basic Protein Inactivates the High Avidity T Cell Repertoire | Q36401074 | ||
Specific T cell recognition of kinetic isomers in the binding of peptide to class II major histocompatibility complex | Q36555812 | ||
Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants | Q36778058 | ||
Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak | Q37147375 | ||
Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice | Q37384851 | ||
Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides | Q37513296 | ||
Determinant selection for T-cell tolerance in HEL-transgenic mice: dissociation between immunogenicity and tolerogenicity | Q41116405 | ||
Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen. | Q41162214 | ||
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. | Q41423746 | ||
Direct binding of autoimmune disease related T cell epitopes to purified Lewis rat MHC class II molecules | Q41472037 | ||
Fine specificity of cytotoxic T lymphocytes primed in vivo either with virus or synthetic lipopeptide vaccine or primed in vitro with peptide | Q41654974 | ||
Low avidity recognition of self-antigen by T cells permits escape from central tolerance. | Q41671634 | ||
Dominant determinants in hen eggwhite lysozyme correspond to the cryptic determinants within its self-homologue, mouse lysozyme: implications in shaping of the T cell repertoire and autoimmunity | Q41900190 | ||
A major T cell determinant from the influenza virus hemagglutinin (HA) can be a cryptic self peptide in HA transgenic mice | Q45764639 | ||
Low avidity recognition of a class II-restricted neo-self peptide by virus-specific T cells | Q45788545 | ||
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice | Q45854348 | ||
A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis. | Q46650203 | ||
Differential Tolerance Is Induced in T Cells Recognizing Distinct Epitopes of Myelin Basic Protein | Q47992214 | ||
Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody | Q52827100 | ||
Lower receptor avidity required for thymic clonal deletion than for effector T-cell function | Q59093837 | ||
Crystallization and preliminary x-ray diffraction studies of two new antigen-antibody (lysozyme-Fab) complexes | Q67982015 | ||
Ligand thresholds at different stages of T cell development | Q68442292 | ||
Antibody-mediated activation of T cell clones as a method for screening hybridomas producing antibodies to the T cell receptor | Q69029053 | ||
P433 | issue | 4 | |
P304 | page(s) | 453-462 | |
P577 | publication date | 1999-10-01 | |
P1433 | published in | Immunity | Q6005457 |
P1476 | title | Quantitative analysis of the T cell repertoire that escapes negative selection | |
P478 | volume | 11 |
Q46785924 | A case of indometacin-induced acute hepatitis developing into chronic autoimmune hepatitis |
Q33824207 | Activated antigen-presenting cells select and present chemically modified peptides recognized by unique CD4 T cells |
Q40187471 | An orthologous non-MHC locus in rats and mice is linked to CD4(+) and CD8(+) T-cell proportion |
Q36232748 | Antigen presentation: lysoyme, autoimmune diabetes, and Listeria--what do they have in common? |
Q35627649 | Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells |
Q35669343 | CD4+ T cells from MHC II‐dependent thymocyte–thymocyte interaction provide efficient help for B cells |
Q36376029 | CD5 maintains tolerance in anergic B cells |
Q37486824 | Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression |
Q34059460 | Comprehensive analysis of contributions from protein conformational stability and major histocompatibility complex class II-peptide binding affinity to CD4+ epitope immunogenicity in HIV-1 envelope glycoprotein |
Q36369568 | Deamidation of asparagine in a major histocompatibility complex-bound peptide affects T cell recognition but does not explain type B reactivity |
Q35794602 | Defining the parameters necessary for T-cell recognition of ligands that vary in potency. |
Q34295082 | Dendritic cells as a tool to induce anergic and regulatory T cells |
Q30481754 | Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules |
Q30080006 | Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo |
Q34048781 | Dissociation of peripheral T cell responses from thymocyte negative selection by weak agonists supports a spare receptor model of T cell activation |
Q34066093 | Distinct recognition by two subsets of T cells of an MHC class II-peptide complex |
Q90950138 | Dormant pathogenic CD4+ T cells are prevalent in the peripheral repertoire of healthy mice |
Q36433047 | Functional redundancy between thymic CD8α+ and Sirpα+ conventional dendritic cells in presentation of blood-derived lysozyme by MHC class II proteins |
Q52716571 | Genetic interaction between two insulin-dependent diabetes susceptibility loci, Idd2 and Idd13, in determining immunoregulatory DN T cell proportion |
Q35300270 | Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-Ak class II molecules |
Q37499321 | How the immune system achieves self-nonself discrimination during adaptive immunity |
Q30309445 | Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation |
Q35861128 | Identification and Phylogeny of the First T Cell Epitope Identified from a Human Gut Bacteroides Species |
Q33943122 | Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease |
Q35573436 | Immunotherapeutic Approaches to Alzheimer's Disease |
Q73406538 | Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion |
Q36959354 | In vivo expansion of the residual tumor antigen-specific CD8+ T lymphocytes that survive negative selection in simian virus 40 T-antigen-transgenic mice. |
Q35169132 | Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease |
Q35024784 | Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets |
Q56880717 | Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function |
Q77060937 | Insights into autoimmunity gained from structural analysis of MHC–peptide complexes |
Q57804810 | LAG-3 inhibits the activation of CD4 T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII |
Q26781316 | Macroautophagy in Endogenous Processing of Self- and Pathogen-Derived Antigens for MHC Class II Presentation |
Q42944732 | Major histocompatibility complex class II presentation of cell-associated antigen is mediated by CD8alpha+ dendritic cells in vivo |
Q39119176 | Mixed functional characteristics correlating with TCR-ligand koff -rate of MHC-tetramer reactive T cells within the naive T-cell repertoire. |
Q73734443 | Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart |
Q37297916 | Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice |
Q36432999 | Neutrophils Influence the Level of Antigen Presentation during the Immune Response to Protein Antigens in Adjuvants |
Q38958324 | On Peptides and Altered Peptide Ligands: From Origin, Mode of Action and Design to Clinical Application (Immunotherapy). |
Q34792432 | Perspective on antigen processing and presentation. |
Q36433065 | Presentation of Type B Peptide–MHC Complexes from Hen Egg White Lysozyme by TLR Ligands and Type I IFNs Independent of H2-DM Regulation |
Q35077155 | Quantitative constraints on the scope of negative selection |
Q35669113 | Register shifting of an insulin peptide–MHC complex allows diabetogenic T cells to escape thymic deletion |
Q35855829 | Role of surfactant protein A in the innate host defense and autoimmunity |
Q35047977 | Role of the immune system in the pathogenesis, prevention and treatment of Alzheimer's disease |
Q37276193 | Salmonella polarises peptide‐MHC‐II presentation towards an unconventional Type B CD4+T‐cell response |
Q36369169 | T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation |
Q61981592 | T cell response to 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) in multiple sclerosis patients |
Q36439289 | T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes |
Q47765737 | T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. |
Q36295994 | T-cells in Alzheimer's disease. |
Q77357457 | The level of peptide-MHC complex determines the susceptibility to autoimmune diabetes: studies in HEL transgenic mice |
Q37078234 | The role of islet antigen presenting cells and the presentation of insulin in the initiation of autoimmune diabetes in the NOD mouse |
Q36426341 | Thymus-blood protein interactions are highly effective in negative selection and regulatory T cell induction |
Q84943150 | Unconventional recognition of peptides by T cells and the implications for autoimmunity |
Q33664653 | Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells |
Q34831727 | Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes |
Q36296691 | Versatility of using major histocompatibility complex class II dextramers for derivation and characterization of antigen-specific, autoreactive T cell hybridomas |
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