scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1015380234 |
P356 | DOI | 10.2165/00002512-200320020-00002 |
P698 | PubMed publication ID | 12534311 |
P5875 | ResearchGate publication ID | 10945620 |
P50 | author | Beatrix Grubeck-Loebenstein | Q21255470 |
P2093 | author name string | Imrich Blasko | |
P2860 | cites work | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 |
Reduced prevalence of AD in users of NSAIDs and H2 receptor antagonists: the Cache County study | Q28138182 | ||
Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1 | Q28139001 | ||
Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP | Q28592685 | ||
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse | Q29619237 | ||
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines | Q29620217 | ||
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation | Q29620219 | ||
Ibuprofen protects dopaminergic neurons against glutamate toxicity in vitro | Q31431931 | ||
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease | Q33292093 | ||
NSAIDS inhibit the IL-1β-induced IL-6 release from human post-mortem astrocytes: the involvement of prostaglandin E2 | Q48552047 | ||
Ibuprofen: effect on inducible nitric oxide synthase | Q48581095 | ||
Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease | Q48652428 | ||
Autoantibodies to amyloid-beta and Alzheimer's disease | Q48839422 | ||
A glia-derived signal regulating neuronal differentiation. | Q52163762 | ||
Cellular and substrate adhesion molecules (integrins) and their ligands in cerebral amyloid plaques in Alzheimer's disease | Q53199812 | ||
Interactions of the Alzheimer beta amyloid fragment (25-35) with peripheral blood dendritic cells | Q53217302 | ||
Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells | Q53220157 | ||
Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. | Q53232489 | ||
Immunization with beta-amyloid: could T-cell activation have a harmful effect? | Q53233148 | ||
The origins of Alzheimer disease: a is for amyloid | Q53233941 | ||
Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia | Q53236835 | ||
Anti-inflammatory drugs protect against Alzheimer disease at low doses | Q53330979 | ||
Infliximab in patients with primary Sj�gren's syndrome: A pilot study | Q56765531 | ||
Region-Specific Neurotrophin Imbalances in Alzheimer Disease | Q57833020 | ||
Tissue distribution of ibuprofen in a fatal overdose | Q70717375 | ||
Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for a cytoprotective response | Q70956389 | ||
The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases | Q71674774 | ||
Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons | Q71786314 | ||
Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: anti-inflammatory without gastropathy? | Q72638568 | ||
Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile | Q72897165 | ||
Quantitative analysis of the T cell repertoire that escapes negative selection | Q73152040 | ||
Permeability and Residual Plasma Volume of Human, Dutch Variant, and Rat Amyloid β-Protein 1-40 at the Blood–Brain Barrier | Q73591093 | ||
Risk of Hospitalization for Upper Gastrointestinal Tract Bleeding Associated With Ketorolac, Other Nonsteroidal Anti-inflammatory Drugs, Calcium Antagonists, and Other Antihypertensive Drugs | Q74071460 | ||
Patients with Alzheimer disease have lower levels of serum anti-amyloid peptide antibodies than healthy elderly individuals | Q74372174 | ||
A chimeric anti-TNFalpha monoclonal antibody (cA2) in vivo removes TNFalpha-producing cells in Crohn's disease | Q74845090 | ||
TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs | Q77747669 | ||
Inhibitory effects of indomethacin on interleukin-1 and nitric oxide production in rat microglia in vitro | Q77811883 | ||
The cause of neuronal degeneration in Alzheimer's disease | Q33819660 | ||
What the evolution of the amyloid protein precursor supergene family tells us about its function | Q33838961 | ||
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline | Q33895797 | ||
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation. | Q33900383 | ||
Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease | Q33943122 | ||
Reduced levels of amyloid beta-peptide antibody in Alzheimer disease | Q34090874 | ||
Neuroendocrine regulation of autoimmune/inflammatory disease | Q34262738 | ||
Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells | Q34309061 | ||
Cyclooxygenase and Alzheimer's disease: implications for preventive initiatives to slow the progression of clinical dementia | Q34312617 | ||
Staging of Alzheimer-related cortical destruction | Q34349510 | ||
The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease | Q34469528 | ||
A RIP tide in neuronal signal transduction | Q34682414 | ||
Effects of treatment with a fully human anti-tumour necrosis factor alpha monoclonal antibody on the local and systemic homeostasis of interleukin 1 and TNFalpha in patients with rheumatoid arthritis. | Q35550664 | ||
A role for the β-amyloid precursor protein in memory? | Q36078010 | ||
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease | Q37118356 | ||
Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells | Q38287673 | ||
Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons | Q38326966 | ||
Novel purification and detailed characterization of perlecan isolated from the Engelbreth-Holm-Swarm tumor for use in an animal model of fibrillar A beta amyloid persistence in brain | Q39114292 | ||
Ibuprofen decreases cytokine-induced amyloid beta production in neuronal cells. | Q40764016 | ||
Antibody-mediated phagocytosis of the amyloid beta-peptide in microglia is differentially modulated by C1q. | Q40801276 | ||
Transfected human B cells: a new model to study the functional and immunostimulatory consequences of APP production | Q40915146 | ||
The non-steroidal anti-inflammatory drug tepoxalin inhibits interleukin-6 and alpha1-anti-chymotrypsin synthesis in astrocytes by preventing degradation of IkappaB-alpha | Q40931699 | ||
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. | Q41067625 | ||
Interleukin-1 beta and tumor necrosis factor-alpha induce expression of alpha 1-antichymotrypsin in human astrocytoma cells by activation of nuclear factor-kappa B. | Q41156846 | ||
Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen. | Q41162214 | ||
APP peptides stimulate lymphocyte proliferation in normals, but not in patients with Alzheimer's disease | Q41187321 | ||
Effects of NSAIDs on IL-1 beta-induced IL-6 mRNA and protein synthesis in human astrocytoma cells | Q41204420 | ||
Suppression of NF kappa B activation and NF kappa B-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase | Q41375412 | ||
Transforming growth factor-betas in neurodegenerative disease | Q41699811 | ||
Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease. | Q41749781 | ||
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease | Q41753192 | ||
IL-1 and anti-inflammatory drugs modulate A beta cytotoxicity in PC12 cells | Q41930560 | ||
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs | Q42551374 | ||
Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease | Q43545917 | ||
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity | Q43793656 | ||
Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. | Q43918834 | ||
Interleukin-6 and α-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices | Q45234030 | ||
Transforming growth factor-beta 1 is in plaques in Alzheimer and Down pathologies. | Q46609616 | ||
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease | Q47583762 | ||
Indomethacin Reverses the Microglial Response to Amyloid β-Protein | Q47854558 | ||
Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures | Q47973688 | ||
Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS. | Q48285765 | ||
The possible role of the immune system in Alzheimer's disease | Q48287927 | ||
Inflammatory molecule release by beta-amyloid-treated T98G astrocytoma cells: role of prostaglandins and modulation by paracetamol | Q48333373 | ||
TrkA immunoreactivity in reactive astrocytes in human neurodegenerative diseases and colchicine-treated rats | Q48342246 | ||
The neuropathological diagnosis of Alzheimer disease | Q48413406 | ||
Neuronal control of the immune response in the central nervous system: linking brain immunity to neurodegeneration | Q48463886 | ||
P433 | issue | 2 | |
P921 | main subject | prevention | Q1717246 |
Alzheimer's disease | Q11081 | ||
P304 | page(s) | 101-113 | |
P577 | publication date | 2003-01-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Drugs & Aging | Q5308946 |
P1476 | title | Role of the immune system in the pathogenesis, prevention and treatment of Alzheimer's disease | |
P478 | volume | 20 |
Q34071942 | Adaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseases |
Q37228055 | CD 4+ T cells in the pathobiology of neurodegenerative disorders |
Q73835307 | Current awareness in geriatric psychiatry |
Q33600342 | Decreased serum brain-derived neurotrophic factor levels in elderly korean with dementia |
Q37462620 | Development of vaccination approaches for the treatment of neurological diseases |
Q47929022 | Electroacupuncture attenuates reference memory impairment associated with astrocytic NDRG2 suppression in APP/PS1 transgenic mice |
Q28566224 | Gene expression of cyclooxygenase-1 and Ca(2+)-independent phospholipase A(2) is altered in rat hippocampus during normal aging |
Q51911828 | High interleukin-6 plasma levels are associated with functional impairment in older patients with vascular dementia |
Q61809067 | Identification of Alzheimer's Disease-Related Genes Based on Data Integration Method |
Q36528564 | Immunizations in the elderly: do they live up to their promise? |
Q36201574 | Immunological aetiology of major psychiatric disorders: evidence and therapeutic implications |
Q59810560 | Immunosenescence of Natural Killer Cells, Inflammation, and Alzheimer's Disease |
Q46909331 | Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease |
Q45938256 | Increase of SCF plasma concentration during donepezil treatment of patients with early Alzheimer's disease. |
Q37062555 | Inflammation as a potential mediator for the association between periodontal disease and Alzheimer's disease |
Q39743698 | Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity |
Q37957125 | Pathways towards an effective immunotherapy for Parkinson's disease |
Q38132922 | Positive and negative effects of prostaglandins in Alzheimer's disease. |
Q53309203 | Premature immunosenescence: a pathogenetic factor in Alzheimer's disease? |
Q46342470 | RAGE-Specific Inhibitor FPS-ZM1 Attenuates AGEs-Induced Neuroinflammation and Oxidative Stress in Rat Primary Microglia |
Q61814310 | Relationship Between Alzheimer's Disease and the Immune System: A Meta-Analysis of Differentially Expressed Genes |
Q34510478 | Relationship of tooth loss to mild memory impairment and cognitive impairment: findings from the fujiwara-kyo study |
Q47404070 | Review: Impact of Helicobacter pylori on Alzheimer's disease: What do we know so far? |
Q53324311 | Role of interleukin 6 and alpha-globulins in differentiating Alzheimer and vascular dementias. |
Q91987428 | Serum Homocysteine and Behavioral and Psychological Symptoms of Dementia: Is There Any Correlation in Alzheimer's Disease? |
Q35563671 | Serum Level of Endogenous Secretory Receptor for Advanced Glycation End Products and Other Factors in Type 2 Diabetic Patients With Mild Cognitive Impairment |
Q44601737 | Serum brain-derived neurotrophic factor is associated with cognitive function in healthy older adults. |
Q34354421 | Serum homocysteine levels are correlated with behavioral and psychological symptoms of Alzheimer's disease |
Q53274532 | Stage-dependent BDNF serum concentrations in Alzheimer's disease |
Q55261711 | Tetrahydroxystilbene glycoside antagonizes β-amyloid-induced inflammatory injury in microglia cells by regulating PU.1 expression. |
Q36045732 | The overtraining syndrome in athletes: a stress-related disorder |
Q34548586 | Toll-like receptors in Alzheimer's disease |
Q57807559 | Tooth loss as a risk factor for dementia: systematic review and meta-analysis of 21 observational studies |
Q39380813 | Treatment strategies in Alzheimer's disease with a focus on early pharmacological interventions |
Q53254799 | Vaccination against Alzheimer disease? |
Q38121457 | Vitamin D Insufficiency in Psychiatric Inpatients |
Q46632689 | [Brain-derived neurotrophic factor: from nerve growth factor to modulator of brain plasticity in cognitive processes and psychiatric diseases]. |
Search more.