Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

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Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells is …
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scholarly articleQ13442814

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P819ADS bibcode1989PNAS...86.7606G
P356DOI10.1073/PNAS.86.19.7606
P932PMC publication ID298115
P698PubMed publication ID2508093
P5875ResearchGate publication ID20648235

P2093author name stringT Hla
D C Gajdusek
R J Donnelly
H W Harris
T Maciag
M P Vitek
D Goldgaber
J S Jacobsen
P2860cites workAmyloid plaque core protein in Alzheimer disease and Down syndromeQ24568384
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Interleukin 1 or endotoxin increases the release of von Willebrand factor from human endothelial cells.Q54760285
Immunocytochemical localization of the precursor protein for beta-amyloid in the rat central nervous systemQ67260747
Altered expression of genes for amyloid and cytoskeletal proteins in Alzheimer cortexQ69063006
Three types of amyloid protein precursor mRNA in human brain: their differential expression in Alzheimer's diseaseQ70414479
Human vascular smooth muscle cells both express and respond to heparin-binding growth factor I (endothelial cell growth factor)Q24634292
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Molecular cloning of amyloid cDNA derived from mRNA of the Alzheimer disease brain: coding and noncoding regions of the fetal precursor mRNA are expressed in the cortexQ33551321
In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer diseaseQ33554297
Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer diseaseQ33554847
Distribution of precursor amyloid-beta-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neuritic plaques.Q33558559
Identification of cellular and extracellular sites of amyloid precursor protein extracytoplasmic domain in normal and Alzheimer disease brainsQ33833369
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer diseaseQ34309107
Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer diseaseQ34341134
Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptidesQ34631864
beta-amyloid protein of Alzheimer's disease is found in cerebral and spinal cord vascular malformationsQ35818563
The promoter of Alzheimer's disease amyloid A4 precursor geneQ36062059
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's diseaseQ36415791
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activityQ36415795
Multiple forms of beta-amyloid peptide precursor RNAs in a single cell typeQ36416395
Absence of mutation in the beta-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's diseaseQ36429038
Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's diseaseQ36447989
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's diseaseQ36482688
Biology of interleukin 1.Q39629154
Astrocytes and lymphocytes: intercellular communication by growth factorsQ40251145
Human growth hormone as a reporter gene in regulation studies employing transient gene expressionQ40667158
Selective reduction of mRNA for the beta-amyloid precursor protein that lacks a Kunitz-type protease inhibitor motif in cortex from Alzheimer brainsQ41254290
Serial propagation of human endothelial cells in vitroQ41368163
Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase CQ42244464
Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanismQ43950463
The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patientsQ44114853
Interleukin-1 and the acute-phase response: induction of mouse liver serum amyloid A mRNA by murine recombinant interleukin-1.Q45988364
A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitorsQ46046983
Interleukin-1 immunoreactive innervation of the human hypothalamusQ48088092
Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer diseaseQ48155835
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locusQ48349302
Interleukin-1 stimulation of astroglial proliferation after brain injuryQ48495530
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril proteinQ48634030
The relationship between senile plaques and cerebral blood vessels in Alzheimer's disease and senile dementia. Morphological mechanism of senile plaque production.Q48920129
Amyloid protein precursor messenger RNAs: differential expression in Alzheimer's disease.Q53186634
Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.Q53190283
Identification in rodents and other species of an mRNA homologous to the human beta-amyloid precursor.Q53191038
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
interleukinsQ194908
P304page(s)7606-7610
P577publication date1989-10-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInterleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells
P478volume86

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