| scholarly article | Q13442814 |
| P50 | author | Emil R. Unanue | Q1336691 |
| P2093 | author name string | Javier A Carrero | |
| Stephen T Ferris | |||
| P2860 | cites work | Innate immunity and intestinal microbiota in the development of Type 1 diabetes | Q24647312 |
| Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity | Q27489852 | ||
| A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes | Q27622298 | ||
| Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice | Q27625365 | ||
| Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes | Q27632133 | ||
| The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity | Q27660688 | ||
| The murine autoimmune diabetes model: NOD and related strains | Q28211565 | ||
| Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells | Q28591976 | ||
| The immune response of mice to antigen in macrophages | Q72096051 | ||
| Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content | Q72140450 | ||
| Prevention of autoimmune insulin-dependent diabetes in non-obese diabetic mice by anti-LFA-1 and anti-ICAM-1 mAb | Q72691713 | ||
| Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes | Q73117342 | ||
| Quantitative analysis of the T cell repertoire that escapes negative selection | Q73152040 | ||
| Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice | Q73299448 | ||
| The insulin-specific T cells of nonobese diabetic mice recognize a weak MHC-binding segment in more than one form | Q80257293 | ||
| Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes | Q80587031 | ||
| Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes | Q81052829 | ||
| Unconventional recognition of peptides by T cells and the implications for autoimmunity | Q84943150 | ||
| Macrophage biology in development, homeostasis and disease | Q29620350 | ||
| Macrophage activation and polarization: nomenclature and experimental guidelines | Q29620642 | ||
| Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules | Q30481754 | ||
| SENSITIZATION TO DENATURED AUTOLOGOUS GAMMA GLOBULIN | Q30494914 | ||
| Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice | Q30498716 | ||
| T cell response to preproinsulin I and II in the nonobese diabetic mouse | Q30844663 | ||
| Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity | Q33220897 | ||
| Prediction of HLA-DQ8beta cell peptidome using a computational program and its relationship to autoreactive T cells | Q33450214 | ||
| Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells | Q33591529 | ||
| Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis | Q33811669 | ||
| Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register | Q33934705 | ||
| The central role of antigen presentation in islets of Langerhans in autoimmune diabetes | Q33986306 | ||
| It's insulin | Q34065086 | ||
| Distinct recognition by two subsets of T cells of an MHC class II-peptide complex | Q34066093 | ||
| Pancreatic islet-specific T-cell clones from nonobese diabetic mice | Q34313103 | ||
| Insulin cell mass is altered in Csf1op/Csf1op macrophage-deficient mice | Q34324718 | ||
| Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice | Q34345367 | ||
| A minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes | Q34452991 | ||
| The pancreas anatomy conditions the origin and properties of resident macrophages | Q34492976 | ||
| Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response | Q34533933 | ||
| Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans | Q34534117 | ||
| Macrophages as APC and the dendritic cell myth | Q34599073 | ||
| The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique | Q34614636 | ||
| Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse | Q34651934 | ||
| Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues | Q34676364 | ||
| Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes | Q34831727 | ||
| Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice | Q34968027 | ||
| Register shifting of an insulin peptide–MHC complex allows diabetogenic T cells to escape thymic deletion | Q35669113 | ||
| Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity | Q35865376 | ||
| Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor. | Q35866588 | ||
| Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse | Q35918236 | ||
| Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells. | Q36155053 | ||
| Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell | Q36209584 | ||
| THE INDUCTION OF AUTOIMMUNITY IN RABBITS FOLLOWING INJECTION OF HETEROLOGOUS OR ALTERED HOMOLOGOUS THYROGLOBULIN | Q36267407 | ||
| Persistence of immunogenicity of antigen after uptake by macrophages | Q36269121 | ||
| Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes | Q36272607 | ||
| Function of macrophages in antigen recognition by guinea pig T lymphocytes. II. Role of the macrophage in the regulation of genetic control of the immune response | Q36272651 | ||
| Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells | Q36275163 | ||
| Humoral Autoimmunity in Type 1 Diabetes: Prediction, Significance, and Detection of Distinct Disease Subtypes | Q36330292 | ||
| Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice | Q36370868 | ||
| Insulin as an autoantigen in NOD/human diabetes | Q36499414 | ||
| Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice | Q36678330 | ||
| Analysis of the spontaneous T cell response to insulin in NOD mice | Q36719300 | ||
| Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice | Q36736666 | ||
| Cutting edge: Macrophages are required for localization of antigen-activated B cells to the follicular perimeter and the subsequent germinal center response | Q36824092 | ||
| Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice | Q36858608 | ||
| Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2). | Q36867736 | ||
| Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children | Q36932173 | ||
| Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes. | Q37246540 | ||
| Antigen presentation in the thymus for positive selection and central tolerance induction | Q37638193 | ||
| Beyond the hormone: insulin as an autoimmune target in type 1 diabetes | Q37893829 | ||
| Antigen presentation events in autoimmune diabetes. | Q37969489 | ||
| Antigen presentation in the autoimmune diabetes of the NOD mouse | Q38185460 | ||
| In APCs, the autologous peptides selected by the diabetogenic I-Ag7 molecule are unique and determined by the amino acid changes in the P9 pocket | Q43860736 | ||
| The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex | Q43926964 | ||
| HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus | Q46138865 | ||
| T-lymphocyte clone specific for pancreatic islet antigen | Q46335815 | ||
| T cells recognize both conformational and cryptic determinants on the insulin molecule | Q46546567 | ||
| Determinant selection is a macrophage dependent immune response gene function | Q46795783 | ||
| Thymic expression of mutated B16:A preproinsulin messenger RNA does not reverse acceleration of NOD diabetes associated with insulin 2 (thymic expressed insulin) knockout | Q46805865 | ||
| T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. | Q47765737 | ||
| Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR. | Q48112618 | ||
| The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes | Q52196097 | ||
| Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci | Q52538455 | ||
| Variations in MHC Class II Antigen Processing and Presentation in Health and Disease | Q52883639 | ||
| Deficiency in type I interferon signaling prevents the early interferon-induced gene signature in pancreatic islets but not type 1 diabetes in NOD mice | Q54419470 | ||
| CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens. | Q55053710 | ||
| Sorting Ourselves Out: Seeking Consensus on Trafficking in the Beta-Cell | Q57374295 | ||
| Persistence of Antigen on the Surface of Macrophages | Q58977065 | ||
| Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain | Q59081148 | ||
| A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus | Q70314155 | ||
| Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies | Q71150178 | ||
| Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing | Q71483393 | ||
| Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes | Q71574976 | ||
| Administration of monoclonal antibodies against vascular cell adhesion molecule-1/very late antigen-4 abrogates predisposing autoimmune diabetes in NOD mice | Q71729717 | ||
| Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice | Q71909256 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 183-201 | |
| P577 | publication date | 2016-07-01 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | The role of islet antigen presenting cells and the presentation of insulin in the initiation of autoimmune diabetes in the NOD mouse | |
| P478 | volume | 272 |
| Q54779226 | Antigen presentation: from cell biology to physiology. |
| Q92398568 | Decoding inflammation, its causes, genomic responses, and emerging countermeasures |
| Q92734901 | Immune Relevant and Immune Deficient Mice: Options and Opportunities in Translational Research |
| Q91691723 | Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation |
| Q59355675 | Lymphocytic choriomeningitis virus Clone 13 infection causes either persistence or acute death dependent on IFN-1, cytotoxic T lymphocytes (CTLs), and host genetics |
| Q64262099 | Macrophage IFN-I signaling promotes autoreactive T cell infiltration into islets in type 1 diabetes model |
| Q91048642 | Perivascular macrophages in health and disease |
| Q90213418 | Response to Comment on Mulukutla et al. Autoantibodies to the IA-2 Extracellular Domain Refine the Definition of "A+" Subtypes of Ketosis-Prone Diabetes. Diabetes Care 2018;41:2637-2640 |
| Q90171472 | The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides |
| Q90498144 | Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms |
| Q49200196 | Type 1 Diabetes: A Chronic Anti-Self-Inflammatory Response |
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