Eosinophil crystalloid granules: structure, function, and beyond

scientific article

Eosinophil crystalloid granules: structure, function, and beyond is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1189/JLB.0212067
P932PMC publication ID3395420
P698PubMed publication ID22672875

P2093author name stringPeter F Weller
Josiane S Neves
Valdirene S Muniz
P2860cites workEosinophils retain their granule major basic protein in a murine model of allergic pulmonary inflammationQ74419909
Eosinophils promote allergic disease of the lung by regulating CD4(+) Th2 lymphocyte functionQ74481539
Airway eosinophils accumulate in the mediastinal lymph nodes but lack antigen-presenting potential for naive T cellsQ79074348
Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthmaQ80427980
Migration and accumulation of eosinophils toward regional lymph nodes after airway allergen challengeQ80852091
G protein-coupled receptors in and on the cell nucleus: a new signaling paradigm?Q81155049
Intelligent granules: are eosinophil crystalloid granules inimitable?Q84385235
Eosinophil granule protein localization in eosinophilic endomyocardial diseaseQ84551006
A transmembrane intracellular estrogen receptor mediates rapid cell signalingQ24294726
Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartmentsQ24299236
Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7Q24597517
Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptorQ24629279
Immunoregulatory roles of eosinophils: a new look at a familiar cellQ24644622
B lymphocytes secrete antigen-presenting vesiclesQ24678522
Persistent cAMP-signals triggered by internalized G-protein-coupled receptorsQ27329609
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cellsQ27860960
Imaging of persistent cAMP signaling by internalized G protein-coupled receptorsQ28279234
Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesisQ28505452
Membrane vesicles as conveyors of immune responsesQ29547765
Exosomes--vesicular carriers for intercellular communicationQ29616652
Eosinophil granules function extracellularly as receptor-mediated secretory organellesQ30484748
Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments.Q30489042
Rapid mobilization of intracellularly stored RANTES in response to interferon-gamma in human eosinophilsQ30724124
Cysteinyl leukotrienes acting via granule membrane-expressed receptors elicit secretion from within cell-free human eosinophil granulesQ33669090
Degranulation patterns of eosinophil granulocytes as determinants of eosinophil driven diseaseQ33943245
Membrane vesicles, current state-of-the-art: emerging role of extracellular vesiclesQ34026858
Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens.Q34430916
Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.Q34480114
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.Q34544553
Eosinophils: multifaceted biological properties and roles in health and diseaseQ34630341
CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cellsQ34662206
Eosinophils: offenders or general bystanders in allergic airway disease and pulmonary immunity?Q34769419
Not just a sink: endosomes in control of signal transductionQ35840127
CCL11 elicits secretion of RNases from mouse eosinophils and their cell-free granulesQ35913057
Contributions of electron microscopy to understand secretion of immune mediators by human eosinophils.Q36169557
Piecemeal degranulation in human eosinophils: a distinct secretion mechanism underlying inflammatory responsesQ36188927
Eosinophil degranulation: an evolutionary vestige or a universally destructive effector function?Q36239677
Endocytosis conducts the cell signaling orchestraQ36418350
Differential secretion of cytokinesQ36498889
High Resolution Autoradiographic Studies of RNA, Protein and DNA Synthesis during Human Eosinophil Granulocytopoiesis: Evidence for the Presence of RNA on or within Eosinophil GranulesQ36602007
Eosinophils in innate immunity: an evolving storyQ36921021
Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteinsQ36944424
Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentiallyQ37062148
Lymph node trafficking and antigen presentation by endobronchial eosinophilsQ37176309
Subcellular fractionation of human eosinophils: isolation of functional specific granules on isoosmotic density gradientsQ37184108
Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils.Q37274179
Biology of the eosinophilQ37397520
Functional extracellular eosinophil granules: novel implications in eosinophil immunobiologyQ37457196
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surfaceQ37475747
G protein-coupled receptors: the inside storyQ37658605
Eosinophils and Th2 immunity: contemporary insightsQ37672261
Signaling by internalized G-protein-coupled receptors.Q37715118
Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptorQ37957225
Cell proliferation and epidermal growth factor signaling in non-small cell lung adenocarcinoma cell lines are dependent on Rin1.Q39830464
How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alphaQ39978313
IFN-gamma and its receptor subunit IFNGR1 are recruited to the IFN-gamma-activated sequence element at the promoter site of IFN-gamma-activated genes: evidence of transactivational activity in IFNGR1.Q40265502
A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells.Q40459685
Human eosinophils produce biologically active IL-12: implications for control of T cell responses.Q41029744
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthmaQ43049820
Localization of DNA and RNA in eosinophil secretory granulesQ43235250
Degranulation status of airway tissue eosinophils in mouse models of allergic airway inflammationQ43540399
Intracellular pool of IL-10 receptors in specific granules of human neutrophils: differential mobilization by proinflammatory mediatorsQ43567129
Extensive eosinophil degranulation and peroxidase-mediated oxidation of airway proteins do not occur in a mouse ovalbumin-challenge model of pulmonary inflammation.Q43683670
Granule changes of human skin mast cells characteristic of piecemeal degranulation and associated with recovery during wound healing in situ.Q43810457
IL-16 promotes leukotriene C(4) and IL-4 release from human eosinophils via CD4- and autocrine CCR3-chemokine-mediated signalingQ43968836
CC chemokine receptor 3 mobilizes to the surface of human mast cells and potentiates immunoglobulin E-dependent generation of interleukin 13.Q44374303
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.Q46017179
Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradationQ46065440
Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumenQ47951192
Endobronchial eosinophils preferentially stimulate T helper cell type 2 responsesQ47988383
Eosinophils: biological properties and role in health and disease.Q51960619
Signaling on the endocytic pathwayQ57359903
The Effect of IL-5 and Eotaxin Expression in the Lung on Eosinophil Trafficking and Degranulation and the Induction of Bronchial HyperreactivityQ57693315
Ultrastructural evidence for piecemeal and anaphylactic degranulation of human gut mucosal mast cells in vivoQ67987787
Development of eosinophilic airway inflammation and airway hyperresponsiveness requires interleukin-5 but not immunoglobulin E or B lymphocytesQ73031872
Piecemeal degranulation of peripheral blood eosinophils: a study of allergic subjects during and out of the pollen seasonQ73038102
Cutting edge: eotaxin elicits rapid vesicular transport-mediated release of preformed IL-4 from human eosinophilsQ73720769
Ultrastructural autoradiographic analysis of RNA in isolated human lung mast cells during secretion and recovery from secretionQ73949086
P433issue2
P304page(s)281-288
P577publication date2012-06-06
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleEosinophil crystalloid granules: structure, function, and beyond
P478volume92

Reverse relations

cites work (P2860)
Q48023702Coinfection with Clonorchis sinensis modulates murine host response against Trichinella spiralis infection
Q54397184Contemporary understanding of the secretory granules in human eosinophils.
Q41044958Cysteinyl Leukotrienes in Eosinophil Biology: Functional Roles and Therapeutic Perspectives in Eosinophilic Disorders
Q53199529Cytolytic degranulation of eosinophils in sputum smears.
Q34225936Development of a suspension array assay in multiplex for the simultaneous measurement of serum levels of four eosinophil granule proteins
Q40954723Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome.
Q92323510Eosinophils in the gastrointestinal tract and their role in the pathogenesis of major colorectal disorders
Q38153632Functional extracellular eosinophil granules: a bomb caught in a trap
Q28260328Multifaceted roles of cysteinyl leukotrienes in eliciting eosinophil granule protein secretion
Q52699143Overview of Basic Immunology for Clinical Investigators.
Q27314997Purinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host Response
Q88540273Specialized Proresolving Mediators in Innate and Adaptive Immune Responses in Airway Diseases
Q38075409Targeting eosinophils in allergy, inflammation and beyond
Q39438308The Biology of Eosinophils and Their Role in Asthma
Q38675311The Eosinophil in Infection
Q28084891The new deal: a potential role for secreted vesicles in innate immunity and tumor progression

Search more.