Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially

scientific article published on 07 October 2008

Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1189/JLB.0108058
P932PMC publication ID2626765
P698PubMed publication ID18840671
P5875ResearchGate publication ID23305066

P2093author name stringPeter F Weller
Lisa A Spencer
Josiane S Neves
Sandra A C Perez
Amy L Radke
Casey L Kirchhoffer
Craig T Szela
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EliCell: a gel-phase dual antibody capture and detection assay to measure cytokine release from eosinophilsQ73081440
Incorporation of cells into an ELISA system enhances antigen-driven lymphokine detectionQ73690836
Eosinophils promote allergic disease of the lung by regulating CD4(+) Th2 lymphocyte functionQ74481539
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous systemQ80102518
Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alphaQ81317318
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Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 CommitmentQ24301442
Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7Q24597517
Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexesQ24671876
Human eosinophils express and release IL-13 following CD28-dependent activationQ28207371
Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytesQ29619621
Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments.Q30489042
Intracellular localization of interleukin-6 in eosinophils from atopic asthmatics and effects of interferon gammaQ32084242
Eosinophil cytokinesQ33889418
Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.Q34480114
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cellsQ34556912
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cellsQ36362214
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthmaQ36369722
Intracrine cysteinyl leukotriene receptor-mediated signaling of eosinophil vesicular transport-mediated interleukin-4 secretionQ36371243
Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cellsQ36376543
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasiteQ36399604
Differential secretion of cytokinesQ36498889
Lymph node trafficking and antigen presentation by endobronchial eosinophilsQ37176309
Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils.Q37274179
Airway eosinophils: allergic inflammation recruited professional antigen-presenting cellsQ37327205
Human eosinophils produce biologically active IL-12: implications for control of T cell responses.Q41029744
Identification of messenger RNA for IL-4 in human eosinophils with granule localization and release of the translated productQ41673322
Mature eosinophils stimulated to develop in human cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. Part I. Piecemeal degranulation of specific granules and distribution of Charcot-Leyden crystal proteinQ41702000
Eosinophils can function as antigen-presenting cells to induce primary and secondary immune responses to Strongyloides stercoralisQ41840474
Mature eosinophils stimulated to develop in human-cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. II. Vesicular transport of specific granule matrix peroxidase, a mechanism for effecting piecemeal degranulatioQ42755866
Yin and yang interplay of IFN-gamma in inflammation and autoimmune diseaseQ42876606
Eokines: synthesis, storage and release from human eosinophilsQ44014774
Helper T cells regulate type-2 innate immunity in vivoQ44154038
Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 productionQ46528021
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.Q55045567
Ultrastructural immunogold localization of tumor necrosis factor-alpha to the matrix compartment of eosinophil secondary granules in patients with idiopathic hypereosinophilic syndromeQ70503913
Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 developmentQ70916529
Subcellular localization of transforming growth factor-alpha in human eosinophil granulocytesQ71029723
P433issue1
P921main subjecthuman eosinophilQ101405048
P304page(s)117-123
P577publication date2008-10-07
P1433published inJournal of Leukocyte BiologyQ1524048
P1476titleHuman eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially
P478volume85

Reverse relations

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