14-3-3 isotypes facilitate coupling of protein kinase C-zeta to Raf-1: negative regulation by 14-3-3 phosphorylation

scientific article

14-3-3 isotypes facilitate coupling of protein kinase C-zeta to Raf-1: negative regulation by 14-3-3 phosphorylation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ3450297
P932PMC publication ID1220759
P698PubMed publication ID10620507

P2093author name stringJ C Van Der Wal
J Van Blitterswijk
M C Van Dijk
P C Van Der Hoeven
P Ruurs
P2860cites work14-3-3Gamma interacts with and is phosphorylated by multiple protein kinase C isoforms in PDGF-stimulated human vascular smooth muscle cellsQ22010465
Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motifQ24311683
Regulation of Raf-1 kinase activity by the 14-3-3 family of proteinsQ24316278
14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent mannerQ24319738
Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activationQ24319934
Activation-modulated association of 14-3-3 proteins with Cbl in T cellsQ24321362
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserineQ24322674
Interaction of the protein kinase Raf-1 with 14-3-3 proteinsQ24329122
Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and functionQ24648178
Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathwaysQ27729753
14-3-3 Proteins Are Essential for RAS/MAPK Cascade Signaling during Pseudohyphal Development in S. cerevisiaeQ27931429
Protein kinase C mu is negatively regulated by 14-3-3 signal transduction proteinsQ28139665
14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domainQ28246442
Interference of BAD (Bcl-xL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11Q28254663
Protein kinase C alpha activates RAF-1 by direct phosphorylationQ28260100
14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter moleculesQ28284411
Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylaseQ28285080
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)Q28297419
The complexity of Raf-1 regulationQ28305850
Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zetaQ28582003
Molecular cloning of rat cDNAs for beta and gamma subtypes of 14-3-3 protein and developmental changes in expression of their mRNAs in the nervous systemQ28583070
Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1Q28609148
The structural basis for 14-3-3:phosphopeptide binding specificityQ29547190
Protein kinase C zeta subspecies from rat brain: its structure, expression, and propertiesQ33852435
Maintenance of G2 arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear importQ33890764
14-3-3 is phosphorylated by casein kinase I on residue 233. Phosphorylation at this site in vivo regulates Raf/14-3-3 interactionQ34445338
14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteinsQ35624026
Expression and structural analysis of 14-3-3 proteins.Q38299549
Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.Q39574246
14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activityQ39575866
Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinaseQ40020874
Bcr and Raf form a complex in vivo via 14-3-3 proteinsQ40789573
Molecular glue: kinase anchoring and scaffold proteinsQ40981719
Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-zeta and Raf-1.Q41099506
PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.Q41144598
Characterization of phorbol ester binding to protein kinase C isotypesQ41316380
Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipidsQ41410908
A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras.Q41526418
Expression and partial characterization of rat protein kinase C-delta and protein kinase C-zeta in insect cells using recombinant baculovirusQ41614557
Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: dependence on protein kinase C-zetaQ42159757
Identification of a key domain in annexin and 14-3-3 proteins that stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cellsQ42620975
Multiple isoforms of a protein kinase C inhibitor (KCIP-1/14-3-3) from sheep brain. Amino acid sequence of phosphorylated formsQ44926293
Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzymeQ45971419
Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 proteinQ46098415
14-3-3 and its possible role in co-ordinating multiple signalling pathwaysQ47986680
Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor developmentQ48050491
Molecular cloning of rat cDNAs for the zeta and theta subtypes of 14-3-3 protein and differential distributions of their mRNAs in the brainQ48080467
Structure and sites of phosphorylation of 14-3-3 protein: role in coordinating signal transduction pathways.Q48667801
Molecular cloning of cDNA to rat 14-3-3 η chain polypeptide and the neuronal expression of the mRNA in the central nervous systemQ48737237
Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo.Q52553630
Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase CQ57979874
Identification of the 14.3.3 zeta domains important for self-association and Raf bindingQ71743225
Apoptosis meets signal transduction: elimination of a BAD influenceQ71802220
Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinaseQ72186416
14-3-3 alpha and delta are the phosphorylated forms of raf-activating 14-3-3 beta and zeta. In vivo stoichiometric phosphorylation in brain at a Ser-Pro-Glu-Lys MOTIFQ72631513
Involvement of phosphatidylcholine-specific phospholipase C in platelet-derived growth factor-induced activation of the mitogen-activated protein kinase pathway in Rat-1 fibroblastsQ73248197
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)297-306
P577publication date2000-01-15
P1433published inBiochemical JournalQ864221
P1476title14-3-3 isotypes facilitate coupling of protein kinase C-zeta to Raf-1: negative regulation by 14-3-3 phosphorylation
P478volume345 Pt 2

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