| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | T Obsil | |
| V Obsilova | |||
| P2860 | cites work | Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway | Q47960215 |
| Negative regulation of the forkhead transcription factor FKHR by Akt. | Q52535267 | ||
| Phylogenetic relationships of the Fox (Forkhead) gene family in the Bilateria | Q58490012 | ||
| 14-3-3 alpha and delta are the phosphorylated forms of raf-activating 14-3-3 beta and zeta. In vivo stoichiometric phosphorylation in brain at a Ser-Pro-Glu-Lys MOTIF | Q72631513 | ||
| Backbone dynamics of a winged helix protein and its DNA complex at different temperatures: changes of internal motions in genesis upon binding to DNA | Q73018986 | ||
| The dissociation rate of a winged helix protein-DNA complex is influenced by non-DNA contact residues | Q78171813 | ||
| Redox properties of cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774 | Q95826003 | ||
| Nuclear localization of protein kinase U-alpha is regulated by 14-3-3 | Q22003811 | ||
| Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 | ||
| Direct control of the Forkhead transcription factor AFX by protein kinase B | Q22009452 | ||
| Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization | Q22254367 | ||
| Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting | Q24290893 | ||
| The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site | Q24291137 | ||
| Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation | Q24291204 | ||
| Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity | Q24298021 | ||
| FOXP3 controls regulatory T cell function through cooperation with NFAT | Q24298179 | ||
| Structure of the forkhead domain of FOXP2 bound to DNA | Q24300742 | ||
| FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP | Q24302269 | ||
| Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding | Q24306703 | ||
| Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase | Q24310456 | ||
| Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a) | Q24313587 | ||
| 14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4 | Q24316897 | ||
| Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins | Q24318768 | ||
| Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine | Q24322674 | ||
| Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending | Q24336507 | ||
| IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a | Q24336832 | ||
| A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span | Q24338599 | ||
| FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1) | Q24338668 | ||
| Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX. | Q24514761 | ||
| 14-3-3 isotypes facilitate coupling of protein kinase C-zeta to Raf-1: negative regulation by 14-3-3 phosphorylation | Q24531905 | ||
| Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues | Q24532085 | ||
| Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation | Q24534597 | ||
| Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion | Q24536290 | ||
| Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon | Q24553133 | ||
| Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation | Q24673179 | ||
| Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B | Q24675116 | ||
| Involvement of 14-3-3 proteins in nuclear localization of telomerase | Q24685623 | ||
| Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding | Q27619633 | ||
| Solution structure and dynamics of the DNA-binding domain of the adipocyte-transcription factor FREAC-11 | Q27621290 | ||
| Structure comparison of two conserved HNF-3/fkh proteins HFH-1 and genesis indicates the existence of folding differences in their complexes with a DNA binding sequence | Q27638150 | ||
| Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification | Q27648799 | ||
| Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways | Q27729753 | ||
| Crystal structure of the zeta isoform of the 14-3-3 protein | Q27729754 | ||
| Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5 | Q27731950 | ||
| Structural changes in the region directly adjacent to the DNA-binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteins | Q27756859 | ||
| Nuclear targeting sequences--a consensus? | Q27860997 | ||
| The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans | Q28131830 | ||
| Solution structure of the DNA binding domain of the human forkhead transcription factor AFX (FOXO4) | Q28188878 | ||
| Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins. | Q36140005 | ||
| 14-3-3 proteins: a historic overview | Q36470005 | ||
| The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino-acid residues adjacent to the recognition helix | Q36651086 | ||
| Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function | Q36653134 | ||
| Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1. | Q40206763 | ||
| CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage | Q40220552 | ||
| JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. | Q40398942 | ||
| FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. | Q40493379 | ||
| JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins | Q40568858 | ||
| Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. | Q40609126 | ||
| Akt activation promotes degradation of tuberin and FOXO3a via the proteasome | Q40679017 | ||
| Bcr and Raf form a complex in vivo via 14-3-3 proteins | Q40789573 | ||
| Regulation of gene expression by insulin | Q41169614 | ||
| FoxO1a-cyclic GMP-dependent kinase I interactions orchestrate myoblast fusion | Q42276834 | ||
| A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin | Q42437256 | ||
| Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence | Q42472986 | ||
| Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding. | Q44702812 | ||
| Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes | Q46402217 | ||
| C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span | Q47068907 | ||
| C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO. | Q47069277 | ||
| Mammalian SIRT1 represses forkhead transcription factors | Q28246430 | ||
| The fork head domain: a novel DNA binding motif of eukaryotic transcription factors? | Q28257620 | ||
| FoxO6 transcriptional activity is regulated by Thr26 and Ser184, independent of nucleo-cytoplasmic shuttling | Q28258996 | ||
| Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily | Q28263013 | ||
| Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1 | Q28273966 | ||
| A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity | Q28276506 | ||
| 14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules | Q28284411 | ||
| Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding | Q28284616 | ||
| Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family | Q28287300 | ||
| Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23) | Q28302260 | ||
| Stressing the role of FoxO proteins in lifespan and disease | Q28303730 | ||
| Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse | Q28508739 | ||
| Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways | Q28588530 | ||
| Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells | Q28591060 | ||
| Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site | Q28610026 | ||
| daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans | Q28611332 | ||
| Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B | Q28638147 | ||
| 14-3-3 Isotypes facilitate coupling of protein kinase C-ζ to Raf-1: negative regulation by 14-3-3 phosphorylation | Q29041812 | ||
| The structural basis for 14-3-3:phosphopeptide binding specificity | Q29547190 | ||
| Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1 | Q29617416 | ||
| Winged helix proteins | Q29617630 | ||
| Forkhead transcription factors: key players in development and metabolism | Q29618804 | ||
| 14-3-3 proteins: structure, function, and regulation | Q29619100 | ||
| Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase | Q29620235 | ||
| FOXO transcription factors at the interface between longevity and tumor suppression | Q29620472 | ||
| 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport | Q33292269 | ||
| Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation | Q33755125 | ||
| JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. | Q33934548 | ||
| How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis | Q34120299 | ||
| 14-3-3 proteins: regulation of subcellular localization by molecular interference | Q34127838 | ||
| Fox's in development and disease | Q34205134 | ||
| Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma | Q34347334 | ||
| 14-3-3 proteins; bringing new definitions to scaffolding | Q34405540 | ||
| JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling | Q34410199 | ||
| The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo | Q34461861 | ||
| The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation | Q35684376 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2263-2275 | |
| P577 | publication date | 2008-04-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Structure/function relationships underlying regulation of FOXO transcription factors | |
| P478 | volume | 27 |
| Q101410361 | "Primary Myxoid and Epithelioid Mesenchymal Tumor of the Kidney with a Novel GLI1-FOXO4 Fusion" |
| Q33439373 | 14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4. |
| Q47637367 | 1α,25-Dihydroxyvitamin D3 promotes bone formation by promoting nuclear exclusion of the FoxO1 transcription factor in diabetic mice |
| Q88913028 | A Phosphomimetic Study Implicates Ser557 in Regulation of FOXP2 DNA Binding |
| Q51015339 | A differential pattern of gene expression in skeletal muscle of tumor-bearing rats reveals dysregulation of excitation–contraction coupling together with additional muscle alterations. |
| Q90575658 | A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma |
| Q40370463 | Activation of silent mating type information regulation 2 homolog 1 by human chorionic gonadotropin exerts a therapeutic effect on hepatic injury and inflammation |
| Q35096324 | Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions |
| Q42006441 | Amino acids activate mammalian target of rapamycin complex 2 (mTORC2) via PI3K/Akt signaling |
| Q37217188 | An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance |
| Q36099721 | Analysis of FOXD3 sequence variation in human ocular disease |
| Q36814631 | Analysis of FOXO1 mutations in diffuse large B-cell lymphoma |
| Q38322918 | Bradykinin inhibits hepatic gluconeogenesis in obese mice |
| Q35696240 | Casein kinase 2 prevents mesenchymal transformation by maintaining Foxc2 in the cytoplasm |
| Q24649127 | Coordinate regulation of FOXO1 by miR-27a, miR-96, and miR-182 in breast cancer cells |
| Q92069595 | Critical physiological and pathological functions of Forkhead Box O tumor suppressors |
| Q33797782 | Cross-regulation between oncogenic BRAF(V600E) kinase and the MST1 pathway in papillary thyroid carcinoma |
| Q27666253 | Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain |
| Q51128779 | Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter |
| Q37618563 | Crystallization and preliminary X-ray analysis of a complex of the FOXO1 and Ets1 DNA-binding domains and DNA. |
| Q47713533 | Cyclic Nucleotide-Directed Protein Kinases in Cardiovascular Inflammation and Growth |
| Q42572335 | DAF-16/Forkhead box O transcription factor: many paths to a single Fork(head) in the road |
| Q24322745 | Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation |
| Q47105930 | Deletion of FoxO1, 3, and 4 in Osteoblast Progenitors Attenuates the Loss of Cancellous Bone Mass in a Mouse Model of Type 1 Diabetes |
| Q58580316 | Epidermal Remodeling in Dauers Requires the Nidogen Domain Protein DEX-1 |
| Q26744673 | FOXN1 in thymus organogenesis and development |
| Q33594004 | FOXO transcription factors: their clinical significance and regulation. |
| Q36889384 | FOXO3 gene variants and human aging: coding variants may not be key players |
| Q92238885 | FOXO3a is stabilized by USP18-mediated de-ISGylation and inhibits TGF-β1-induced fibronectin expression |
| Q37052939 | FOXOs attenuate bone formation by suppressing Wnt signaling. |
| Q34256593 | Forkhead box O1 and muscle RING finger 1 protein expression in atrophic and hypertrophic denervated mouse skeletal muscle |
| Q28080067 | Forkhead box transcription factor 1: role in the pathogenesis of diabetic cardiomyopathy |
| Q39000854 | Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a. |
| Q26863387 | Fox tales: regulation of gonadotropin gene expression by forkhead transcription factors |
| Q38069459 | FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival |
| Q28570206 | FoxO3a is activated and executes neuron death via Bim in response to β-amyloid |
| Q39053123 | FoxO3a is an antimelanogenic factor that mediates antioxidant-induced depigmentation |
| Q47350816 | Foxo1 nucleo-cytoplasmic distribution and unidirectional nuclear influx are the same in nuclei in a single skeletal muscle fiber but vary between fibers. |
| Q42694441 | From the Cover: Autophagy Induction Contributes to Cadmium Toxicity in Mesenchymal Stem Cells via AMPK/FOXO3a/BECN1 Signaling |
| Q48235777 | Functional Analysis of Promoters from Three Subtypes of the PI3K Family and Their Roles in the Regulation of Lipid Metabolism by Insulin in Yellow Catfish Pelteobagrus fulvidraco. |
| Q104111366 | Functional crosstalk between myeloid Foxo1-β-catenin axis and Hedgehog/Gli1 signaling in oxidative stress response |
| Q33526330 | Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G). |
| Q34492548 | Highly specialized role of Forkhead box O transcription factors in the immune system. |
| Q36225357 | Hypoxia-inducible factor 1-α-AA-modified bone marrow stem cells protect PC12 cells from hypoxia-induced apoptosis, partially through VEGF/PI3K/Akt/FoxO1 pathway |
| Q38247021 | IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity |
| Q34528355 | Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways |
| Q33994414 | LATS1 phosphorylates forkhead L2 and regulates its transcriptional activity |
| Q36454186 | Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice |
| Q26800194 | MAPK/JNK signalling: a potential autophagy regulation pathway |
| Q58543659 | Mathematical Modeling of Nuclear Trafficking of FOXO Transcription Factors |
| Q37629038 | Mathematical modeling reveals modulation of both nuclear influx and efflux of Foxo1 by the IGF-I/PI3K/Akt pathway in skeletal muscle fibers |
| Q38932625 | Mechanisms of transcription factor acetylation and consequences in hearts. |
| Q59335899 | Mediated nuclear import and export of TAZ and the underlying molecular requirements |
| Q24645523 | Mesenchymal-epithelial transition in epithelial response to injury: the role of Foxc2 |
| Q28072056 | MicroRNAs as regulators and mediators of forkhead box transcription factors function in human cancers |
| Q38802040 | Mitochondrial FOXO3a is involved in amyloid β peptide-induced mitochondrial dysfunction |
| Q33612153 | Modelling the response of FOXO transcription factors to multiple post-translational modifications made by ageing-related signalling pathways |
| Q91797826 | Molecular networks of FOXP family: dual biologic functions, interplay with other molecules and clinical implications in cancer progression |
| Q90149358 | Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis |
| Q91791623 | New insights into the roles of the FOXO3 and P27Kip1 genes in signaling pathways |
| Q34571572 | Overexpression of wild-type but not C134W mutant FOXL2 enhances GnRH-induced cell apoptosis by increasing GnRH receptor expression in human granulosa cell tumors. |
| Q38770073 | Performance of nano-assembly logic gates with a DNA multi-hairpin motif. |
| Q38492153 | Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity |
| Q26799843 | Redox regulation of FoxO transcription factors |
| Q50057271 | Regulation of FOXO Factors in Mammalian Cells. |
| Q39883289 | Regulation of neuronal cell death by MST1-FOXO1 signaling |
| Q51825137 | Regulation of p38, PKC/Foxo3a/p73 signaling network by GTP during erythroid differentiation in chronic myelogenous leukemia. |
| Q35128706 | Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models |
| Q38647185 | Role of Forkhead Box Class O proteins in cancer progression and metastasis |
| Q53629703 | SIRT1 Protects Against Oxidative Stress-Induced Endothelial Progenitor Cells Apoptosis by Inhibiting FOXO3a via FOXO3a Ubiquitination and Degradation. |
| Q51701430 | SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia. |
| Q36083385 | STAT3 mediates resistance to MEK inhibitor through microRNA miR-17. |
| Q36216383 | STAT3 protein interacts with Class O Forkhead transcription factors in the cytoplasm and regulates nuclear/cytoplasmic localization of FoxO1 and FoxO3a proteins in CD4(+) T cells |
| Q61816619 | Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autophagy |
| Q27667284 | Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: Insight into its domain swapping and DNA binding |
| Q34514818 | Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models |
| Q37872655 | Targeting phosphatidylinositol 3 kinase (PI3K)-Akt beyond rapalogs |
| Q58581301 | The Dominant Role of Forkhead Box Proteins in Cancer |
| Q37776729 | The Extending Network of FOXO Transcriptional Target Genes |
| Q90663773 | The FOXO's Advantages of Being a Family: Considerations on Function and Evolution |
| Q47359487 | The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance |
| Q54680284 | The STOX1 genotype associated with pre-eclampsia leads to a reduction of trophoblast invasion by alpha-T-catenin upregulation. |
| Q42803561 | The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway |
| Q42809852 | The forkhead transcription factor FOXO1 stimulates the expression of the adipocyte resistin gene. |
| Q60917471 | The forkhead-box family of transcription factors: key molecular players in colorectal cancer pathogenesis |
| Q42067514 | The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors |
| Q101564352 | Therapeutic strategies targeting FOXO transcription factors |
| Q37716386 | Transcription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer |
| Q35126991 | Unraveling the role of FoxOs in bone--insights from mouse models |
| Q36183357 | Zebrafish foxo3b Negatively Regulates Antiviral Response through Suppressing the Transactivity of irf3 and irf7. |
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