FoxO3a is activated and executes neuron death via Bim in response to β-amyloid

scientific article

FoxO3a is activated and executes neuron death via Bim in response to β-amyloid is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1009834165
P356DOI10.1038/CDDIS.2013.148
P3181OpenCitations bibliographic resource ID691298
P932PMC publication ID3674357
P698PubMed publication ID23661003
P5875ResearchGate publication ID236675133

P2093author name stringS C Biswas
P Sanphui
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APP binds DR6 to trigger axon pruning and neuron death via distinct caspasesQ22251088
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Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNKQ24808691
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AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamilyQ28252659
Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamilyQ28263013
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Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene familyQ28287300
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)Q28302260
Stressing the role of FoxO proteins in lifespan and diseaseQ28303730
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamicsQ28504819
Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylationQ28576927
FOXO transcription factors at the interface between longevity and tumor suppressionQ29620472
FOXOs, cancer and regulation of apoptosisQ33642512
Fluoxetine protects against amyloid-beta toxicity, in part via daf-16 mediated cell signaling pathway, in Caenorhabditis elegansQ34079552
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcomaQ34347334
Men are but worms: neuronal cell death in C elegans and vertebratesQ35597043
Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicityQ36004208
Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins.Q36140005
Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agentsQ36255573
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicityQ36321606
Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's diseaseQ36528274
Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.Q36538200
Regulation of forkhead transcription factor FoxO3a contributes to calorie restriction-induced prevention of Alzheimer's disease-type amyloid neuropathology and spatial memory deteriorationQ37020746
The insulin/Akt signaling pathway is targeted by intracellular beta-amyloidQ37112633
Structure/function relationships underlying regulation of FOXO transcription factorsQ37129790
Resveratrol and neurodegenerative diseases: activation of SIRT1 as the potential pathway towards neuroprotectionQ37438243
Effects of injected Alzheimer beta-amyloid cores in rat brain.Q37596908
Applications of post-translational modifications of FoxO family proteins in biological functionsQ37888960
Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.Q38321058
Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicinQ39435517
Insulin-activated Akt rescues Aβ oxidative stress-induced cell death by orchestrating molecular trafficking.Q39533821
Synaptic NMDAR activity suppresses FOXO1 expression via a cis-acting FOXO binding site: FOXO1 is a FOXO target geneQ39578579
Regulation of neuronal cell death by MST1-FOXO1 signalingQ39883289
Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt.Q40333129
BH3-only proteins: key regulators of neuronal apoptosisQ42542936
FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neuronsQ42918105
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathwayQ43909621
Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.Q44323443
Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.Q46297094
Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death.Q46958357
Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis.Q48298601
Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition.Q48620889
Inhibition of JNK/dFOXO pathway and caspases rescues neurological impairments in Drosophila Alzheimer's disease modelQ48664192
Impaired glutamatergic and GABAergic function at early age in AβPPswe-PS1dE9 mice: implications for Alzheimer's disease.Q53324090
Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling PathwaysQ58287598
Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal NeuronsQ62608643
Caspase-2 mediates neuronal cell death induced by beta-amyloidQ73419649
Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-proteinQ74736370
RAIDD is required for apoptosis of PC12 cells and sympathetic neurons induced by trophic factor withdrawalQ81833471
P4510describes a project that usesImageJQ1659584
P304page(s)e625
P577publication date2013-05-09
P1433published inCell Death and DiseaseQ2197222
P1476titleFoxO3a is activated and executes neuron death via Bim in response to β-amyloid
P478volume4

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cites work (P2860)
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