Activation of S1P₁ receptor regulates PI3K/Akt/FoxO3a pathway in response to oxidative stress in PC12 cells

scientific article published on 23 December 2014

Activation of S1P₁ receptor regulates PI3K/Akt/FoxO3a pathway in response to oxidative stress in PC12 cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1017402761
P356DOI10.1007/S12031-014-0478-1
P698PubMed publication ID25534920

P50authorLeila DargahiQ43236236
P2093author name stringAbolhassan Ahmadiani
Behzad Khallaghi
Fatemeh Safarian
P2860cites workAkt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factorQ22009126
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Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1.Q42854212
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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neuronsQ42918105
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Novel immunomodulator FTY720 is phosphorylated in rats and humans to form a single stereoisomer. Identification, chemical proof, and biological characterization of the biologically active species and its enantiomerQ46633328
Sphingosine can pre- and post-condition heart and utilizes a different mechanism from sphingosine 1-phosphateQ46639803
Pramipexole protects against H2O2-induced PC12 cell deathQ46857211
Stearic acid protects primary cultured cortical neurons against oxidative stressQ48271947
Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cellsQ48729588
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Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells.Q50909674
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Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway.Q54499703
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Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regenerationQ64380167
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Nerve growth factor prevents the apoptosis-associated increase in acetylcholinesterase activity after hydrogen peroxide treatment by activating AktQ79530363
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P433issue1
P304page(s)177-187
P577publication date2014-12-23
P1433published inJournal of Molecular NeuroscienceQ15708870
P1476titleActivation of S1P₁ receptor regulates PI3K/Akt/FoxO3a pathway in response to oxidative stress in PC12 cells
P478volume56

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cites work (P2860)
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