| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1022899866 |
| P356 | DOI | 10.1038/NCB1469 |
| P3181 | OpenCitations bibliographic resource ID | 1618106 |
| P698 | PubMed publication ID | 16964248 |
| P5875 | ResearchGate publication ID | 232775093 |
| P50 | author | Madelon M Maurice | Q58368128 |
| P2093 | author name string | Arjan B Brenkman | |
| Frédéric Colland | |||
| Boudewijn M T Burgering | |||
| Armando van der Horst | |||
| Alida M M de Vries-Smits | |||
| Miranda H van Triest | |||
| Niels van den Broek | |||
| P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
| Direct control of the Forkhead transcription factor AFX by protein kinase B | Q22009452 | ||
| AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 | Q22254000 | ||
| Negative control of p53 by Sir2alpha promotes cell survival under stress | Q24291828 | ||
| hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase | Q24291829 | ||
| Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization | Q24292930 | ||
| Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity | Q24298021 | ||
| Nonhydrolyzable diubiquitin analogues are inhibitors of ubiquitin conjugation and deconjugation | Q74138474 | ||
| Functional proteomics mapping of a human signaling pathway | Q24298398 | ||
| Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2 | Q24303581 | ||
| Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase | Q24310456 | ||
| Growth suppression by p16ink4 requires functional retinoblastoma protein | Q24317567 | ||
| FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1) | Q24338668 | ||
| Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues | Q24532085 | ||
| Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors | Q24537205 | ||
| Regulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451 | Q24548249 | ||
| Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation | Q24673179 | ||
| Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells | Q28207530 | ||
| GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7 | Q28238126 | ||
| Mammalian SIRT1 represses forkhead transcription factors | Q28246430 | ||
| A dynamic role of HAUSP in the p53-Mdm2 pathway | Q28253645 | ||
| Mechanism and function of deubiquitinating enzymes | Q28295758 | ||
| Identification of mono-ubiquitinated LDH-A in skeletal muscle cells exposed to oxidative stress | Q28571897 | ||
| DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein | Q28577209 | ||
| Cell cycle and death control: long live Forkheads | Q28646130 | ||
| A proteomics approach to understanding protein ubiquitination | Q29547312 | ||
| Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction | Q29618388 | ||
| Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress | Q29619436 | ||
| FOXO transcription factors at the interface between longevity and tumor suppression | Q29620472 | ||
| Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation | Q29622825 | ||
| Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation | Q33755125 | ||
| JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. | Q33934548 | ||
| Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family | Q34156341 | ||
| JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling | Q34410199 | ||
| Mechanisms controlling EGF receptor endocytosis and degradation | Q35594146 | ||
| Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins | Q37535142 | ||
| Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes. | Q37570487 | ||
| FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. | Q40493379 | ||
| Akt activation promotes degradation of tuberin and FOXO3a via the proteasome | Q40679017 | ||
| Ubiquitination and degradation of the Arg tyrosine kinase is regulated by oxidative stress | Q45286153 | ||
| LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans | Q46704659 | ||
| PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2) | Q73617626 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | regulation of DNA-binding transcription factor activity | Q14820066 |
| Forkhead box O4 | Q21109294 | ||
| Ubiquitin specific peptidase 7 | Q21109614 | ||
| P304 | page(s) | 1064-73 | |
| P577 | publication date | 2006-10-01 | |
| P1433 | published in | Nature Cell Biology | Q1574111 |
| P1476 | title | FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP | |
| P478 | volume | 8 |
| Q27680523 | A Role for USP7 in DNA Replication |
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| Q36549512 | A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling |
| Q37389377 | A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells |
| Q39991228 | A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model |
| Q38712894 | AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction. |
| Q42243995 | ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage |
| Q37360483 | Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin |
| Q47135501 | Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60. |
| Q37614692 | Adding more content to screening: reactivation of FOXO as a therapeutic strategy |
| Q37888960 | Applications of post-translational modifications of FoxO family proteins in biological functions |
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| Q24656652 | Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes |
| Q27331617 | C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress |
| Q37718344 | CDDO-Me reveals USP7 as a novel target in ovarian cancer cells |
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| Q92542887 | Considering the Role of Murine Double Minute 2 in the Cardiovascular System? |
| Q28547943 | Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7 |
| Q28085121 | Cullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signaling |
| Q90140626 | Current perspective on the regulation of FOXO4 and its role in disease progression |
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| Q38336126 | DUBs, the regulation of cell identity and disease |
| Q31152155 | Data integration in physiology using Bayes' rule and minimum Bayes' factors: deubiquitylating enzymes in the renal collecting duct |
| Q24322745 | Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation |
| Q41923220 | Deregulation of FOXO3A during prostate cancer progression |
| Q38326071 | Deubiquitinases and the new therapeutic opportunities offered to cancer |
| Q35955141 | Deubiquitinases in cancer |
| Q37945451 | Deubiquitinases in cancer: new functions and therapeutic options. |
| Q36536984 | Deubiquitinating enzymes as novel anticancer targets |
| Q36232579 | Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling |
| Q36535326 | Deubiquitination of NF-κB by Ubiquitin-Specific Protease-7 promotes transcription |
| Q30415089 | Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway |
| Q41838441 | Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells |
| Q38125278 | Deubiquitylases from genes to organism |
| Q38109871 | Deubiquitylating enzymes and DNA damage response pathways |
| Q21284381 | Deubiquitylating enzymes and disease |
| Q48265884 | Deubiquitylating enzymes and drug discovery: emerging opportunities. |
| Q43178154 | Diabetic cardiomyopathy: catabolism driving metabolism |
| Q38687425 | Diabetic cardiomyopathy: role of the E3 ubiquitin ligase |
| Q48188572 | Discovery and characterization of highly potent and selective allosteric USP7 inhibitors |
| Q37976004 | Dissecting cell death with proteomic scalpels |
| Q45900041 | E3 ubiquitin ligase NKLAM ubiquitinates STAT1 and positively regulates STAT1-mediated transcriptional activity. |
| Q21131571 | EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication |
| Q64286900 | EGFR and Prion protein promote signaling via FOXO3a-KLF5 resulting in clinical resistance to platinum agents in colorectal cancer |
| Q59357734 | Emerging insights into HAUSP (USP7) in physiology, cancer and other diseases |
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| Q39554519 | Enzymatic assays for assessing histone deubiquitylation activity. |
| Q33373662 | Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies |
| Q30609320 | Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling |
| Q36858443 | Expression of HAUSP in gliomas correlates with disease progression and survival of patients |
| Q51546149 | FBXO31 protects against genomic instability by capping FOXM1 levels at the G2/M transition. |
| Q26776415 | FOXO factors and breast cancer: outfoxing endocrine resistance |
| Q33594004 | FOXO transcription factors: their clinical significance and regulation. |
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| Q59811797 | FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas |
| Q34173809 | FOXO1: a potential target for human diseases |
| Q37356540 | FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells |
| Q54375099 | FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3. |
| Q38074598 | FOXOs: signalling integrators for homeostasis maintenance |
| Q41962935 | FOXP in Tetrapoda: Intrinsically Disordered Regions, Short Linear Motifs and their evolutionary significance |
| Q92874259 | Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics |
| Q38121578 | Forkhead box class O transcription factors in liver function and disease |
| Q64447846 | Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis |
| Q39000854 | Forkhead followed by disordered tail: The intrinsically disordered regions of FOXO3a. |
| Q43246853 | FoxO genes are dispensable during gastrulation but required for late embryogenesis in Xenopus laevis |
| Q36663162 | FoxO transcription factors in the maintenance of cellular homeostasis during aging |
| Q42636934 | FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf. |
| Q36334327 | FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis |
| Q34362813 | FoxO, autophagy, and cardiac remodeling |
| Q37129806 | Foxo in the immune system |
| Q36413441 | GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1 expression via activation of AMPK/FOXO3a pathway |
| Q34193241 | Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors |
| Q41545001 | Genome-wide association study of antibody level response to NDV and IBV in Jinghai yellow chicken based on SLAF-seq technology |
| Q37387937 | HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma |
| Q79168398 | HAUSP hunting the FOX(O) |
| Q52947230 | HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP. |
| Q24297641 | HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulator |
| Q35913537 | HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response |
| Q30395512 | Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway |
| Q37311332 | Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity. |
| Q37361776 | Histone H2B ubiquitination: the cancer connection |
| Q36785057 | How the ubiquitin proteasome system regulates the regulators of transcription |
| Q47552231 | Human Herpesvirus 8 Interferon Regulatory Factors 1 and 3 Mediate Replication and Latency Activities via Interactions with USP7 Deubiquitinase |
| Q58116151 | Identification and Characterization of USP7 Targets in Cancer Cells |
| Q52655073 | Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors. |
| Q36566682 | Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer |
| Q36922997 | Immune regulation by Foxo transcription factors |
| Q33802926 | Inactivation of HAUSP in vivo modulates p53 function |
| Q33792527 | Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosis |
| Q95648224 | Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy |
| Q30427503 | Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression |
| Q47206865 | Isolation and initial characterization of GW5, a major QTL associated with rice grain width and weight |
| Q42930872 | Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins |
| Q41466923 | Isopeptidases in anticancer therapy: looking for inhibitors. |
| Q24338903 | JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress |
| Q37149786 | JWA regulates XRCC1 and functions as a novel base excision repair protein in oxidative-stress-induced DNA single-strand breaks |
| Q42044297 | Lysosomal localization of ubiquitinated Jun requires multiple determinants in a lysine-27-linked polyubiquitin conjugate |
| Q35882313 | M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability |
| Q28250621 | MBD4 interacts with and recruits USP7 to heterochromatic foci |
| Q39868313 | MDM2 acts downstream of p53 as an E3 ligase to promote FOXO ubiquitination and degradation. |
| Q21092186 | Mdm2 induces mono-ubiquitination of FOXO4 |
| Q40133177 | Mechanistic studies of MDM2-mediated ubiquitination in p53 regulation |
| Q35879654 | Membrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen |
| Q36209138 | Methylation by Set9 modulates FoxO3 stability and transcriptional activity. |
| Q33612153 | Modelling the response of FOXO transcription factors to multiple post-translational modifications made by ageing-related signalling pathways |
| Q38644746 | Modulation of NF-κB Signaling as a Therapeutic Target in Autoimmunity. |
| Q28075457 | Modulation of the p53/MDM2 interplay by HAUSP inhibitors |
| Q34248458 | Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation |
| Q40037116 | Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells |
| Q24295012 | Monoubiquitylation promotes mitochondrial p53 translocation |
| Q38066579 | Moving to the core: spatiotemporal analysis of Forkhead box O (FOXO) and nuclear factor-κB (NF-κB) nuclear translocation |
| Q34071699 | NFX1-LIKE2 (NFXL2) suppresses abscisic acid accumulation and stomatal closure in Arabidopsis thaliana |
| Q37739372 | New insights for FOXO and cell-fate decision in HIV infection and HIV associated neurocognitive disorder |
| Q28594861 | Novel variant of neuronal intranuclear rodlet immunoreactive for 40 kDa huntingtin associated protein and ubiquitin in the mouse brain |
| Q92529034 | Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease |
| Q34352254 | Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma |
| Q28570758 | O-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stress |
| Q54647572 | Oxidative Stress-Dependent Regulation of Forkhead Box O4 Activity by Nemo-Like Kinase |
| Q37245117 | Oxidative stress in the regulation of normal and neoplastic hematopoiesis |
| Q35951377 | PLK1 is a binding partner and a negative regulator of FOXO3 tumor suppressor |
| Q50058849 | Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains. |
| Q33307875 | Patented small molecule inhibitors in the ubiquitin proteasome system |
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| Q91714281 | Pinning Down the Transcription: A Role for Peptidyl-Prolyl cis-trans Isomerase Pin1 in Gene Expression |
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| Q36515754 | The Caenorhabditis elegans ekl (enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway |
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| Q36065142 | The Deubiquitinating Enzyme USP7 Regulates Androgen Receptor Activity by Modulating Its Binding to Chromatin. |
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| Q33815705 | The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies |
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| Q24304410 | XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling |
| Q37882073 | p53 regulation by ubiquitin |
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