| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Wei Gu | |
| Omid Tavana | |||
| P2860 | cites work | A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains | Q24291050 |
| Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization | Q24292930 | ||
| Critical role for Daxx in regulating Mdm2 | Q24297332 | ||
| Daxx is reciprocally regulated by Mdm2 and Hausp | Q24299167 | ||
| Role of the Ras-association domain family 1 tumor suppressor gene in human cancers | Q36113844 | ||
| A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance | Q36338365 | ||
| Deubiquitination of NF-κB by Ubiquitin-Specific Protease-7 promotes transcription | Q36535326 | ||
| Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities | Q36662171 | ||
| Ubiquitin-specific protease 7 expression is a prognostic factor in epithelial ovarian cancer and correlates with lymph node metastasis | Q36716292 | ||
| Expression of HAUSP in gliomas correlates with disease progression and survival of patients | Q36858443 | ||
| USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation | Q36944526 | ||
| Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis | Q36951802 | ||
| Mdm2-mediated ubiquitylation: p53 and beyond. | Q37508606 | ||
| USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis | Q37577477 | ||
| The multifaceted roles of USP7: new therapeutic opportunities | Q37862125 | ||
| Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End. | Q38872379 | ||
| FoxO6 inhibits cell proliferation in lung carcinoma through up-regulation of USP7. | Q38908181 | ||
| Nucleotide biosynthetic enzyme GMP synthase is a TRIM21-controlled relay of p53 stabilization | Q39030913 | ||
| Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes | Q39437160 | ||
| Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47. | Q39730830 | ||
| Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells | Q39813804 | ||
| The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network | Q39948774 | ||
| A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model | Q39991228 | ||
| Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization | Q40103058 | ||
| Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format | Q41837023 | ||
| Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells | Q41838441 | ||
| Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60. | Q42811467 | ||
| C-terminal region of USP7/HAUSP is critical for deubiquitination activity and contains a second mdm2/p53 binding site | Q42917799 | ||
| Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7. | Q42936312 | ||
| Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination | Q56969633 | ||
| The HAUSP gene plays an important role in non-small cell lung carcinogenesis through p53-dependent pathways | Q82438565 | ||
| FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP | Q24302269 | ||
| Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2 | Q24303581 | ||
| Molecular recognition of p53 and MDM2 by USP7/HAUSP | Q24304312 | ||
| TSPYL5 suppresses p53 levels and function by physical interaction with USP7 | Q24317937 | ||
| The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex | Q24323508 | ||
| A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein | Q24532092 | ||
| Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes | Q24645701 | ||
| Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes | Q24656652 | ||
| Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway | Q25255608 | ||
| Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde | Q27640257 | ||
| Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase | Q27674789 | ||
| Structure of USP7 catalytic domain and three Ubl-domains reveals a connector α-helix with regulatory role | Q27704874 | ||
| Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation | Q27721616 | ||
| Breaking the chains: structure and function of the deubiquitinases | Q28131738 | ||
| GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7 | Q28238126 | ||
| Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization | Q28243346 | ||
| A dynamic role of HAUSP in the p53-Mdm2 pathway | Q28253645 | ||
| Tumour suppression: disruption of HAUSP gene stabilizes p53 | Q28254102 | ||
| ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation | Q28265951 | ||
| A genomic and functional inventory of deubiquitinating enzymes | Q28284911 | ||
| USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder | Q28607464 | ||
| USP7 is a SUMO deubiquitinase essential for DNA replication | Q28834083 | ||
| Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway | Q30415089 | ||
| Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. | Q30884723 | ||
| Inactivation of HAUSP in vivo modulates p53 function | Q33802926 | ||
| Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. | Q34049065 | ||
| Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme | Q34240760 | ||
| ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53. | Q34385189 | ||
| DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination | Q35048728 | ||
| Roles of HAUSP-mediated p53 regulation in central nervous system development | Q35098801 | ||
| USP7 overexpression predicts a poor prognosis in lung squamous cell carcinoma and large cell carcinoma | Q35221054 | ||
| M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability | Q35882313 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 45-52 | |
| P577 | publication date | 2017-02-01 | |
| P1433 | published in | Journal of Molecular Cell Biology | Q2456339 |
| P1476 | title | Modulation of the p53/MDM2 interplay by HAUSP inhibitors | |
| P478 | volume | 9 |
| Q59355907 | Deregulation of methionine metabolism as determinant of progression and prognosis of hepatocellular carcinoma |
| Q48188572 | Discovery and characterization of highly potent and selective allosteric USP7 inhibitors |
| Q50026699 | Drug development: Allosteric inhibitors hit USP7 hard |
| Q37676245 | Dynamics of p53: A Master Decider of Cell Fate |
| Q88679101 | EB 2017 Article: Soy protein isolate feeding does not result in reproductive toxicity in the pre-pubertal rat testis |
| Q52593708 | EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers. |
| Q47552231 | Human Herpesvirus 8 Interferon Regulatory Factors 1 and 3 Mediate Replication and Latency Activities via Interactions with USP7 Deubiquitinase |
| Q92383608 | Impressionist portraits of mitotic exit: APC/C, K11-linked ubiquitin chains and Cezanne |
| Q64068383 | Increase in the nuclear localization of PTEN by the Toxoplasma GRA16 protein and subsequent induction of p53-dependent apoptosis and anticancer effect |
| Q57490982 | Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy |
| Q91923645 | Inhibition of p53 inhibitors: progress, challenges and perspectives |
| Q60907800 | Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity |
| Q89581369 | Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth |
| Q96348276 | Regulating tumor suppressor genes: post-translational modifications |
| Q48319353 | Regulation of the Mdm2-p53 pathway by the ubiquitin E3 ligase MARCH7. |
| Q52332504 | Targeting HAUSP in both p53 wildtype and p53-mutant tumors. |
| Q92002855 | Targeting USP7-Mediated Deubiquitination of MDM2/MDMX-p53 Pathway for Cancer Therapy: Are We There Yet? |
| Q60300288 | Ten years for JMCB |
| Q90003158 | Tumor suppressor p53 and metabolism |
| Q90100499 | USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin |
| Q104073444 | When the chains do not break: the role of USP10 in physiology and pathology |
| Q91701515 | p53 modifications: exquisite decorations of the powerful guardian |
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