scholarly article | Q13442814 |
P50 | author | Yan Li | Q89581365 |
P2093 | author name string | Xue Li | |
Lin Chen | |||
Lingmei Kong | |||
Qihong Yang | |||
Tao An | |||
Aizhu Duan | |||
Xiaoman Ju | |||
Bicheng Cai | |||
P2860 | cites work | The ubiquitin ligase RNF220 enhances canonical Wnt signaling through USP7-mediated deubiquitination of β-catenin | Q24304871 |
Identification of c-MYC as a target of the APC pathway | Q24310637 | ||
Drugging the undruggables: exploring the ubiquitin system for drug development | Q26752823 | ||
Modulation of the p53/MDM2 interplay by HAUSP inhibitors | Q28075457 | ||
Clinical use of proteasome inhibitors in the treatment of multiple myeloma | Q28080999 | ||
A dynamic role of HAUSP in the p53-Mdm2 pathway | Q28253645 | ||
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway | Q28640887 | ||
Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions | Q29248430 | ||
Parthenolide promotes apoptotic cell death and inhibits the migration and invasion of SW620 cells | Q33679117 | ||
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. | Q34049065 | ||
Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme | Q34240760 | ||
The cellular thermal shift assay for evaluating drug target interactions in cells | Q34432745 | ||
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase | Q34517140 | ||
Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling | Q35690072 | ||
Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling | Q36232579 | ||
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance | Q36338365 | ||
Deubiquitination of NF-κB by Ubiquitin-Specific Protease-7 promotes transcription | Q36535326 | ||
MEKK2 mediates an alternative β-catenin pathway that promotes bone formation | Q36659117 | ||
Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis | Q36951802 | ||
Modulation of DNA methylation by a sesquiterpene lactone parthenolide | Q37168514 | ||
HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma | Q37387937 | ||
Targeting the ubiquitin system in cancer therapy | Q37424802 | ||
Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity | Q37604627 | ||
Deubiquitinase USP9X deubiquitinates β-catenin and promotes high grade glioma cell growth | Q37694810 | ||
Deubiquitinases in cancer: new functions and therapeutic options. | Q37945451 | ||
Parthenolide: from plant shoots to cancer roots | Q38108036 | ||
USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status | Q38703821 | ||
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth. | Q38715762 | ||
Inhibitory effects of parthenolide on the activity of NF-κB in multiple myeloma via targeting TRAF6. | Q38864359 | ||
A Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells. | Q38902055 | ||
USP7 controls Chk1 protein stability by direct deubiquitination | Q38931404 | ||
Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47. | Q39730830 | ||
Role of cysteine residues of p65/NF-kappaB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential | Q44925951 | ||
Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions. | Q46093140 | ||
USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination | Q47149840 | ||
Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies. | Q48304688 | ||
The plant sesquiterpene lactone parthenoide inhibits Wnt/β-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1. | Q49806538 | ||
The stability of epigenetic factor ASXL1 is regulated through ubiquitination and USP7-mediated deubiquitination. | Q52954094 | ||
Ubiquitin-specific protease 7 accelerates p14(ARF) degradation by deubiquitinating thyroid hormone receptor-interacting protein 12 and promotes hepatocellular carcinoma progression. | Q53225430 | ||
Drug makers target ubiquitin proteasome pathway anew. | Q53444544 | ||
Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma. | Q54977194 | ||
Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin | Q57494119 | ||
USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia | Q58116419 | ||
Emergence of Members of TRAF and DUB of Ubiquitin Proteasome System in the Regulation of Hypertrophic Cardiomyopathy | Q58728912 | ||
Usp7 regulates Hippo pathway through deubiquitinating the transcriptional coactivator Yorkie | Q61124626 | ||
USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia | Q61816131 | ||
EZH2 Regulates Protein Stability via Recruiting USP7 to Mediate Neuronal Gene Expression in Cancer Cells | Q64067892 | ||
Deubiquitinating enzymes as cancer biomarkers: new therapeutic opportunities? | Q64098664 | ||
USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization | Q88985377 | ||
Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases | Q89157942 | ||
LINC00265 promotes colorectal tumorigenesis via ZMIZ2 and USP7-mediated stabilization of β-catenin | Q90134953 | ||
Overexpression of USP5 contributes to tumorigenesis in non-small cell lung cancer via the stabilization of β-catenin protein | Q90573185 | ||
USP7: Structure, substrate specificity, and inhibition | Q91936479 | ||
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells | Q91959062 | ||
Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease | Q92529034 | ||
Development of Novel Epoxyketone-Based Proteasome Inhibitors as a Strategy To Overcome Cancer Resistance to Carfilzomib and Bortezomib | Q92970395 | ||
A Selective Inhibitor of Ubiquitin-Specific Protease 4 Suppresses Colorectal Cancer Progression by Regulating β-Catenin Signaling | Q93099070 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
ImageQuant | Q112270642 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | colorectal cancer | Q188874 |
cell growth | Q189159 | ||
P304 | page(s) | 3576-3589 | |
P577 | publication date | 2020-02-06 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth | |
P478 | volume | 295 |
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