| scholarly article | Q13442814 |
| P50 | author | Benedikt M. Kessler | Q30504197 |
| Roman Fischer | Q42035488 | ||
| Joanna F. McGouran | Q43268873 | ||
| Holger B. Kramer | Q50635553 | ||
| Mikael Altun | Q56056872 | ||
| Lianne I Willems | Q59531439 | ||
| Jason L Parsons | Q63654558 | ||
| Mukram Mohamed Mackeen | Q91624116 | ||
| Rebecca Konietzny | Q114402244 | ||
| P2093 | author name string | Grigory L Dianov | |
| Svetlana V Khoronenkova | |||
| K G Suresh Kumar | |||
| Benjamin Nicholson | |||
| Seth J Goldenberg | |||
| Craig A Leach | |||
| Jeffrey L McDermott | |||
| Edward Kogan | |||
| P433 | issue | 11 | |
| P304 | page(s) | 1401-1412 | |
| P577 | publication date | 2011-11-01 | |
| P1433 | published in | Chemistry and Biology | Q15758410 |
| P1476 | title | Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes | |
| P478 | volume | 18 |
| Q36948372 | A High-Throughput Screening Method for Identification of Inhibitors of the Deubiquitinating Enzyme USP14 |
| Q47158922 | A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN. |
| Q51462359 | A SUMO and ubiquitin code coordinates protein traffic at replication factories. |
| Q84210891 | A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate |
| Q39016031 | A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study |
| Q38810435 | A new ER-specific photosensitizer unravels (1)O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT. |
| Q39071774 | A population-based analysis of germline BAP1 mutations in melanoma. |
| Q34089593 | A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. |
| Q47135501 | Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60. |
| Q51524293 | Activity Based Profiling of Deubiquitylating Enzymes and Inhibitors in Animal Tissues. |
| Q38829124 | Activity-Based Probes for HECT E3 Ubiquitin Ligases |
| Q28547188 | Activity-Based Proteomic Profiling of Deubiquitinating Enzymes in Salmonella-Infected Macrophages Leads to Identification of Putative Function of UCH-L5 in Inflammasome Regulation |
| Q41936075 | Activity-based diubiquitin probes for elucidating the linkage specificity of deubiquitinating enzymes |
| Q39135148 | Activity-based probes for the ubiquitin conjugation-deconjugation machinery: new chemistries, new tools, and new insights |
| Q45345903 | Analysis of PTEN ubiquitylation and SUMOylation using molecular traps. |
| Q47445829 | Analysis of defective protein ubiquitylation associated to adriamycin resistant cells. |
| Q37718344 | CDDO-Me reveals USP7 as a novel target in ovarian cancer cells |
| Q38280690 | Catching a DUB in the act: novel ubiquitin-based active site directed probes |
| Q38239700 | Cell death and deubiquitinases: perspectives in cancer |
| Q48194799 | Ceylonins G-I: spongian diterpenes from the marine sponge Spongia ceylonensis |
| Q38799376 | Chemical and semisynthetic approaches to study and target deubiquitinases. |
| Q90293202 | Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics |
| Q38108538 | Could dysregulation of UPS be a common underlying mechanism for cancer and neurodegeneration? Lessons from UCHL1. |
| Q38522634 | Creating a customized intracellular niche: subversion of host cell signaling by Legionella type IV secretion system effectors |
| Q26741797 | DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic Targets |
| Q38336126 | DUBs, the regulation of cell identity and disease |
| Q26823930 | Detection of ubiquitin-proteasome enzymatic activities in cells: application of activity-based probes to inhibitor development |
| Q91866950 | Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion |
| Q30683490 | Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis |
| Q35955141 | Deubiquitinases in cancer |
| Q90088711 | Deubiquitinases: Pro-oncogenic Activity and Therapeutic Targeting in Blood Malignancies |
| Q98771233 | Deubiquitinating Enzyme: A Potential Secondary Checkpoint of Cancer Immunity |
| Q27003153 | Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 |
| Q35056872 | Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes |
| Q27026189 | Deubiquitinating enzymes as oncotargets |
| Q33836097 | Deubiquitinating enzymes as promising drug targets for infectious diseases |
| Q30415089 | Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway |
| Q90589697 | Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells |
| Q92369638 | Deubiquitylase USP7 regulates human terminal erythroid differentiation by stabilizing GATA1 |
| Q38125278 | Deubiquitylases from genes to organism |
| Q38109871 | Deubiquitylating enzymes and DNA damage response pathways |
| Q48265884 | Deubiquitylating enzymes and drug discovery: emerging opportunities. |
| Q90350830 | Diarylcarbonates are a new class of deubiquitinating enzyme inhibitor |
| Q48188572 | Discovery and characterization of highly potent and selective allosteric USP7 inhibitors |
| Q38196269 | Discovery of Therapeutic Deubiquitylase Effector Molecules: Current Perspectives |
| Q42291846 | Dual-utility NLS drives RNF169-dependent DNA damage responses. |
| Q37651974 | Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation |
| Q83227339 | Dynamic ubiquitination determines transcriptional activity of the plant immune coactivator NPR1 |
| Q37410632 | Emerging therapies targeting the ubiquitin proteasome system in cancer |
| Q58214389 | Fluorescence-based active site probes for profiling deubiquitinating enzymes |
| Q38705188 | Functional characterization of the neuron-restrictive silencer element in the human tryptophan hydroxylase 2 gene expression. |
| Q37387937 | HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma |
| Q26825542 | Histone H2B monoubiquitination: roles to play in human malignancy |
| Q58116151 | Identification and Characterization of USP7 Targets in Cancer Cells |
| Q35217897 | Immunohistochemical detection of FLAG-tagged endogenous proteins in knock-in mice |
| Q28082497 | Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds |
| Q47716589 | Inhibition of USP10 induces degradation of oncogenic FLT3. |
| Q91923645 | Inhibition of p53 inhibitors: progress, challenges and perspectives |
| Q39149915 | Inhibition of protein deubiquitination by PR-619 activates the autophagic pathway in OLN-t40 oligodendroglial cells |
| Q38626145 | Inhibitors of Deubiquitinating Enzymes Block HIV-1 Replication and Augment the Presentation of Gag-Derived MHC-I Epitopes. |
| Q51524427 | Isolation of the Ubiquitin-Proteome from Tumor Cell Lines and Primary Cells Using TUBEs. |
| Q36163471 | Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. |
| Q38644746 | Modulation of NF-κB Signaling as a Therapeutic Target in Autoimmunity. |
| Q28075457 | Modulation of the p53/MDM2 interplay by HAUSP inhibitors |
| Q47633676 | Molecular basis of USP7 inhibition by selective small-molecule inhibitors |
| Q38822748 | Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future |
| Q39368869 | Multiple functions of long non-coding RNAs in oxidative stress, DNA damage response and cancer progression. |
| Q30358299 | Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase. |
| Q92529034 | Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease |
| Q27676208 | On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases |
| Q58542910 | Otubain 1: a non-canonical deubiquitinase with an emerging role in cancer |
| Q34788381 | Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system. |
| Q36455332 | Post-translational O-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter |
| Q92233313 | Profiling DUBs and Ubl-specific proteases with activity-based probes |
| Q51364802 | Profiling the Activity of Deubiquitinating Enzymes Using Chemically Synthesized Ubiquitin-Based Probes. |
| Q38530227 | Protein aggregate formation in oligodendrocytes: tau and the cytoskeleton at the intersection of neuroprotection and neurodegeneration |
| Q89935029 | Re-Evaluating the Mechanism of Action of α,β-Unsaturated Carbonyl DUB Inhibitors b-AP15 and VLX1570: A Paradigmatic Example of Unspecific Protein Cross-linking with Michael Acceptor Motif-Containing Drugs |
| Q38725385 | Recent Advances in the Discovery of Deubiquitinating Enzyme Inhibitors |
| Q36666402 | Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. |
| Q111285544 | Regulation of Cancer Metabolism by Deubiquitinating Enzymes: The Warburg Effect |
| Q47111924 | Release of Enzymatically Active Deubiquitinating Enzymes upon Reversible Capture by Disulfide Ubiquitin Reagents |
| Q34627914 | SILAC-based quantitative proteomic analysis of human lung cell response to copper oxide nanoparticles |
| Q38837130 | SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis |
| Q35232335 | Screening of DUB activity and specificity by MALDI-TOF mass spectrometry |
| Q35344020 | Sculpting the proteome with small molecules |
| Q39730830 | Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47. |
| Q38181181 | Selective and reversible inhibitors of ubiquitin-specific protease 7: a patent evaluation (WO2013030218). |
| Q58609310 | Seneca Valley Virus 3C protease negatively regulates the type I interferon pathway by acting as a viral deubiquitinase |
| Q95276662 | Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases |
| Q64234008 | Small molecule activators of the p53 response |
| Q38181445 | Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome system |
| Q47108833 | Stabilization of the transcription factors slug and twist by the deubiquitinase dub3 is a key requirement for tumor metastasis |
| Q27865263 | Strategies to Identify Recognition Signals and Targets of SUMOylation. |
| Q47619828 | Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. |
| Q24299250 | Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass |
| Q34564656 | Target identification of small molecules based on chemical biology approaches |
| Q52332504 | Targeting HAUSP in both p53 wildtype and p53-mutant tumors. |
| Q34954162 | Targeting RNA binding proteins involved in neurodegeneration |
| Q92002855 | Targeting USP7-Mediated Deubiquitination of MDM2/MDMX-p53 Pathway for Cancer Therapy: Are We There Yet? |
| Q38059739 | Targeting the ubiquitin-mediated proteasome degradation of p53 for cancer therapy |
| Q87038902 | Targeting the ubiquitin-proteasome system for cancer therapy |
| Q37158445 | Targeting ubiquitination for cancer therapies. |
| Q90083269 | The Deubiquitinating Enzyme Inhibitor PR-619 is a Potent DNA Topoisomerase II Poison |
| Q36449307 | The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance. |
| Q57840406 | The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway |
| Q92511672 | The Role of Deubiquitinases in Oncovirus and Host Interactions |
| Q35909722 | The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors. |
| Q37517626 | The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics |
| Q27308968 | The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates |
| Q28267230 | The role of UBL domains in ubiquitin-specific proteases |
| Q39008850 | The role of deubiquitinases in breast cancer. |
| Q64288182 | The role of ubiquitin-specific peptidases in cancer progression |
| Q90093670 | The role of ubiquitination in tumorigenesis and targeted drug discovery |
| Q36057485 | Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates |
| Q37644227 | Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2. |
| Q38128426 | USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy. |
| Q52723469 | USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells. |
| Q97570298 | USP4 function and multifaceted roles in cancer: a possible and potential therapeutic target |
| Q63246433 | USP7 Regulates Cytokinesis through FBXO38 and KIF20B |
| Q58749340 | USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation |
| Q38931404 | USP7 controls Chk1 protein stability by direct deubiquitination |
| Q38918184 | USP7 cooperates with SCML2 to regulate the activity of PRC1. |
| Q37577477 | USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis |
| Q28834083 | USP7 is a SUMO deubiquitinase essential for DNA replication |
| Q64079043 | USP7: Novel Drug Target in Cancer Therapy |
| Q91936479 | USP7: Structure, substrate specificity, and inhibition |
| Q52659137 | Ube2V2 Is a Rosetta Stone Bridging Redox and Ubiquitin Codes, Coordinating DNA Damage Responses. |
| Q84174712 | Ubiquitin-based anticancer therapy: carpet bombing with proteasome inhibitors vs surgical strikes with E1, E2, E3, or DUB inhibitors |
| Q39271369 | Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes |
| Q38261255 | Ubiquitin-binding domains: mechanisms of ubiquitin recognition and use as tools to investigate ubiquitin-modified proteomes |
| Q38047273 | Unraveling the ubiquitin-regulated signaling networks by mass spectrometry-based proteomics. |
| Q41824768 | Using antiubiquitin antibodies to probe the ubiquitination state within rhTRIM5α cytoplasmic bodies. |
| Q42908737 | Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway |
| Q36990010 | Visualizing K48 Ubiquitination during Presynaptic Formation By Ubiquitination-Induced Fluorescence Complementation (UiFC). |
| Q91701515 | p53 modifications: exquisite decorations of the powerful guardian |
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