review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Jinbao Liu | |
Hongbiao Huang | |||
Ningning Liu | |||
Q. Ping Dou | |||
P2860 | cites work | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction | Q24292709 |
Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome | Q24305134 | ||
The ubiquitin-specific protease USP28 is required for MYC stability | Q24308568 | ||
Suppression of cancer cell growth by promoting cyclin D1 degradation | Q24317660 | ||
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling | Q24318750 | ||
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice | Q24616207 | ||
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes | Q24645701 | ||
The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells | Q24651419 | ||
Functions of the 19S complex in proteasomal degradation | Q26996345 | ||
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction | Q27650666 | ||
Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2 | Q27661655 | ||
Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. | Q27932109 | ||
A cryptic protease couples deubiquitination and degradation by the proteasome | Q27938068 | ||
Breaking the chains: structure and function of the deubiquitinases | Q28131738 | ||
Identification of the familial cylindromatosis tumour-suppressor gene | Q28145560 | ||
Gold compounds as therapeutic agents for human diseases | Q28243207 | ||
Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53 | Q28245322 | ||
The history of gold therapy for tuberculosis | Q28249467 | ||
MiR-4782-3p inhibited non-small cell lung cancer growth via USP14. | Q51110014 | ||
Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid-beta peptide. | Q53293533 | ||
Sanggenon C decreases tumor cell viability associated with proteasome inhibition | Q95811372 | ||
The JAMM motif of human deubiquitinase Poh1 is essential for cell viability | Q28284132 | ||
The 19 S proteasomal subunit POH1 contributes to the regulation of c-Jun ubiquitination, stability, and subcellular localization | Q28304241 | ||
A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14 | Q28359750 | ||
Over-expression of deubiquitinating enzyme USP14 in lung adenocarcinoma promotes proliferation through the accumulation of β-catenin | Q28385613 | ||
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance | Q28395203 | ||
Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response | Q28481001 | ||
Enhancement of proteasome activity by a small-molecule inhibitor of USP14 | Q29616735 | ||
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway | Q29616746 | ||
The 26S proteasome: a molecular machine designed for controlled proteolysis | Q29619692 | ||
A mutation linked to retinitis pigmentosa in HPRP31 causes protein instability and impairs its interactions with spliceosomal snRNPs. | Q30375617 | ||
Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13). | Q30496086 | ||
Gold(III) compounds as new family of anticancer drugs. | Q31150569 | ||
Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells | Q33199028 | ||
Copper-triggered aggregation of ubiquitin | Q33503629 | ||
A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases | Q33729793 | ||
Effect of ubiquitin carboxy-terminal hydrolase 37 on apoptotic in A549 cells | Q33810416 | ||
A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication | Q34150998 | ||
A novel copper complex induces paraptosis in colon cancer cells via the activation of ER stress signalling | Q34169479 | ||
Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth | Q34221890 | ||
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia | Q34231446 | ||
MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling | Q34420804 | ||
The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling | Q34435000 | ||
Ubiquitin C-terminal Hydrolase 37, a novel predictor for hepatocellular carcinoma recurrence, promotes cell migration and invasion via interacting and deubiquitinating PRP19. | Q34503527 | ||
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. | Q34556881 | ||
Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes | Q34607942 | ||
Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms | Q34619261 | ||
KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer | Q34793532 | ||
Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes | Q34994389 | ||
Gold(III)-dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy: preclinical studies against human breast neoplasia. | Q35083349 | ||
USP14 inhibitor IU1 prevents ventilator-induced lung injury in rats. | Q35242436 | ||
Iminophosphorane-organogold(III) complexes induce cell death through mitochondrial ROS production | Q35446994 | ||
Ubiquitin homeostasis is critical for synaptic development and function | Q35659611 | ||
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance | Q36338365 | ||
Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits | Q36354014 | ||
Copper in medicine: homeostasis, chelation therapy and antitumor drug design | Q36412904 | ||
Dithiocarbamate-based coordination compounds as potent proteasome inhibitors in human cancer cells | Q36837031 | ||
1,10-Phenanthroline promotes copper complexes into tumor cells and induces apoptosis by inhibiting the proteasome activity. | Q36869057 | ||
Overexpression of USP14 protease reduces I-κB protein levels and increases cytokine release in lung epithelial cells | Q36890519 | ||
Gold complexes as prospective metal-based anticancer drugs | Q36977891 | ||
Copper: an essential metal in biology | Q37031388 | ||
The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapy | Q37175850 | ||
Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo. | Q37254808 | ||
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. | Q37342850 | ||
USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis | Q37577477 | ||
Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation | Q37610733 | ||
Structural biology of the proteasome | Q38081952 | ||
Regulation of TRAIL-receptor expression by the ubiquitin-proteasome system. | Q38260461 | ||
A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents | Q38979471 | ||
The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death. | Q39006249 | ||
Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer. | Q39034883 | ||
Proapoptotic effects of the novel proteasome inhibitor b-AP15 on multiple myeloma cells and natural killer cells | Q39051768 | ||
Deubiquitinase inhibition of 19S regulatory particles by 4-arylidene curcumin analog AC17 causes NF-κB inhibition and p53 reactivation in human lung cancer cells. | Q39148869 | ||
A novel inhibitor of proteasome deubiquitinating activity renders tumor cells sensitive to TRAIL-mediated apoptosis by natural killer cells and T cells. | Q39149515 | ||
Deubiquitinases as potential anti-cancer targets for gold(III) complexes | Q39158500 | ||
Ubiquitin C-terminal hydrolase-L5 is required for high glucose-induced transforming growth factor-β receptor I expression and hypertrophy in mesangial cells | Q39180071 | ||
The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: implications for neurodegenerative diseases | Q39352352 | ||
Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes | Q39437160 | ||
Inhibition of proteasome deubiquitinating activity as a new cancer therapy | Q39447379 | ||
Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis. | Q39636568 | ||
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival | Q39761203 | ||
Auranofin, an immunosuppressive drug, inhibits MHC class I and MHC class II pathways of antigen presentation in dendritic cells | Q39992342 | ||
Inhibition of the proteasome activity by gallium(III) complexes contributes to their anti prostate tumor effects | Q40073607 | ||
Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action | Q40136607 | ||
Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts | Q40169646 | ||
Antiproliferative and apoptotic effects of two new gold(III) methylsarcosinedithiocarbamate derivatives on human acute myeloid leukemia cells in vitro. | Q40177156 | ||
A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts. | Q40213112 | ||
Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells. | Q40274015 | ||
Gold(III) dithiocarbamate derivatives for the treatment of cancer: solution chemistry, DNA binding, and hemolytic properties | Q40310092 | ||
UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease | Q40540062 | ||
The essential 26S proteasome subunit Rpn11 confers multidrug resistance to mammalian cells | Q40674587 | ||
Gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo | Q43675946 | ||
Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties, and in vitro antitumor activity. | Q46372854 | ||
[History of gold--with danish contribution to tuberculosis and rheumatoid arthritis]. | Q46529108 | ||
Effects of zinc pyrithione and copper pyrithione on microbial community function and structure in sediments. | Q47737159 | ||
New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications | Q47861024 | ||
Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity | Q48381026 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 457-66 | |
P577 | publication date | 2015-05-31 | |
P1433 | published in | Oncoscience | Q27725796 |
P1476 | title | Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds | |
P478 | volume | 2 |
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