| scholarly article | Q13442814 |
| P50 | author | Xuejun Wang | Q38361109 |
| P2093 | author name string | Xin Chen | |
| Chong Zhao | |||
| Jinbao Liu | |||
| Xiaofen Li | |||
| Hongbiao Huang | |||
| Ningning Liu | |||
| Changshan Yang | |||
| Dan Zang | |||
| Yuning Liao | |||
| Xianping Shi | |||
| Jinjie Wu | |||
| Xiaoying Lan | |||
| Huidan Long | |||
| Jianyu Cai | |||
| Xianliang Hua | |||
| P2860 | cites work | Regulation of cell cycle progression and gene expression by H2A deubiquitination | Q24296401 |
| Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds | Q28082497 | ||
| Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase | Q28296183 | ||
| Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase | Q28302692 | ||
| A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance | Q28395203 | ||
| Deubiquitinases (DUBs) and DUB inhibitors: a patent review | Q28834608 | ||
| Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors | Q29547463 | ||
| A screen for deubiquitinating enzymes involved in the G₂/M checkpoint identifies USP50 as a regulator of HSP90-dependent Wee1 stability. | Q34142357 | ||
| Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth | Q34221890 | ||
| Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia | Q34231446 | ||
| Physiological levels of ATP negatively regulate proteasome function. | Q34376187 | ||
| L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro | Q34472177 | ||
| HERC2-USP20 axis regulates DNA damage checkpoint through Claspin | Q34579692 | ||
| Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms | Q34619261 | ||
| Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells | Q35551964 | ||
| Deubiquitinases in cancer | Q35955141 | ||
| Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib. | Q36254571 | ||
| Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response | Q36322641 | ||
| Gambogic acid enhances proteasome inhibitor-induced anticancer activity | Q36869779 | ||
| Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress. | Q36879064 | ||
| Overexpression of USP14 Protease Reduces I-κB Protein Levels and Increases Cytokine Release in Lung Epithelial Cells | Q36890519 | ||
| Reverse the curse--the role of deubiquitination in cell cycle control | Q37112275 | ||
| Disulfiram eradicates tumor-initiating hepatocellular carcinoma cells in ROS-p38 MAPK pathway-dependent and -independent manners | Q37472766 | ||
| Gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl downregulation | Q37610733 | ||
| Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage | Q37616054 | ||
| Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo | Q37726102 | ||
| Deubiquitinases in cancer: new functions and therapeutic options. | Q37945451 | ||
| The biological activity of auranofin: implications for novel treatment of diseases | Q38042341 | ||
| Deubiquitinase inhibition as a cancer therapeutic strategy | Q38274749 | ||
| Deubiquitinases and the new therapeutic opportunities offered to cancer | Q38326071 | ||
| Controlling the unfolded protein response-mediated life and death decisions in cancer. | Q38392861 | ||
| The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80. | Q38860961 | ||
| Copper signaling axis as a target for prostate cancer therapeutics | Q38947366 | ||
| Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity | Q38959150 | ||
| Protective role of humanin on bortezomib-induced bone growth impairment in anticancer treatment. | Q39019344 | ||
| Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide | Q39263561 | ||
| Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G. | Q41375336 | ||
| Potentiation of nitrogen mustard cytotoxicity by disulfiram, diethyldithiocarbamic acid, and diethylamine in mice | Q45347622 | ||
| Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity | Q48381026 | ||
| Evaluation of the in vivo antitumor activity and in vitro cytotoxic properties of auranofin, a coordinated gold compound, in murine tumor models | Q69936658 | ||
| Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response | Q74359929 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2796-2808 | |
| P577 | publication date | 2015-11-28 | |
| P1433 | published in | Oncotarget | Q1573155 |
| P1476 | title | Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo | |
| P478 | volume | 7 |
| Q42362660 | A novel deubiquitinase inhibitor b-AP15 triggers apoptosis in both androgen receptor-dependent and -independent prostate cancers. |
| Q37745339 | Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer |
| Q55028564 | Developing a genetic signature to predict drug response in ovarian cancer. |
| Q57163862 | Discovering proteasomal deubiquitinating enzyme inhibitors for cancer therapy: lessons from rational design, nature and old drug reposition |
| Q64892039 | Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma. |
| Q92882661 | Gold(I/III)-Phosphine Complexes as Potent Antiproliferative Agents |
| Q48529877 | Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination |
| Q64055607 | Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer |
| Q64284866 | Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide |
| Q47098444 | Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents |
| Q98200506 | Mitochondrial TXNRD3 confers drug resistance via redox-mediated mechanism and is a potential therapeutic target in vivo |
| Q37440054 | Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms. |
| Q58577738 | Planarians as models to investigate the bioactivity of gold(I) complexes in vivo |
| Q41335233 | Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation. |
| Q33801982 | Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibition |
| Q47609532 | Recent Advances in Antabuse (Disulfiram): the importance of its metal-binding ability to its anticancer activity. |
| Q47135396 | Selection and characterization of a human ovarian cancer cell line resistant to auranofin |
| Q52676432 | The harsh microenvironment in infarcted heart accelerates transplanted bone marrow mesenchymal stem cells injury: the role of injured cardiomyocytes-derived exosomes |
| Q59134245 | Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells |
| Q64078011 | USP10 modulates the SKP2/Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia |
| Q92447080 | Vitamin B12b Enhances the Cytotoxicity of Diethyldithiocarbamate in a Synergistic Manner, Inducing the Paraptosis-Like Death of Human Larynx Carcinoma Cells |
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