| scholarly article | Q13442814 |
| P50 | author | Haico van Attikum | Q56991345 |
| Dimitris Typas | Q57026401 | ||
| Martijn S Luijsterburg | Q94474082 | ||
| Wouter W Wiegant | Q114261195 | ||
| Angela Helfricht | Q114261227 | ||
| P2093 | author name string | Haico van Attikum | |
| Peter E Thijssen | |||
| Bram van den Broek | |||
| Michaela Diakatou | |||
| P2860 | cites work | Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair | Q21145054 |
| TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes | Q24295574 | ||
| Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1 | Q24296739 | ||
| The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks | Q24298486 | ||
| RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling | Q24298746 | ||
| Human USP3 is a chromatin modifier required for S phase progression and genome stability | Q24299488 | ||
| MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 | ||
| RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
| RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
| The E3 ligase RNF8 regulates KU80 removal and NHEJ repair | Q24302499 | ||
| Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response | Q24306765 | ||
| RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites | Q24306789 | ||
| Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response | Q24306807 | ||
| The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks | Q24309142 | ||
| The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage | Q24309181 | ||
| Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition | Q64388338 | ||
| RAD18 transmits DNA damage signalling to elicit homologous recombination repair | Q37344711 | ||
| PALB2 links BRCA1 and BRCA2 in the DNA-damage response | Q37361223 | ||
| RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks | Q37421389 | ||
| Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair | Q37474898 | ||
| BRCA1 and its toolbox for the maintenance of genome integrity | Q37507563 | ||
| USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15. | Q37587018 | ||
| Assembly of checkpoint and repair machineries at DNA damage sites | Q37624182 | ||
| Chromatin and the DNA damage response: the cancer connection. | Q37904144 | ||
| Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity | Q38959150 | ||
| Germline mutations in BAP1 impair its function in DNA double-strand break repair | Q38988548 | ||
| Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining | Q39105540 | ||
| The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases | Q39160987 | ||
| Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling | Q39221344 | ||
| The USP1/UAF1 complex promotes double-strand break repair through homologous recombination | Q39560571 | ||
| 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair | Q39750906 | ||
| PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. | Q39827885 | ||
| A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase | Q42249588 | ||
| RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins | Q24309287 | ||
| Defining the human deubiquitinating enzyme interaction landscape | Q24315885 | ||
| PALB2 is an integral component of the BRCA complex required for homologous recombination repair | Q24316113 | ||
| MERIT40 facilitates BRCA1 localization and DNA damage repair | Q24317291 | ||
| RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX | Q24317544 | ||
| ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks | Q24321489 | ||
| Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks | Q24339324 | ||
| XRCC3 promotes homology-directed repair of DNA damage in mammalian cells | Q24597771 | ||
| The DNA-damage response in human biology and disease | Q24606586 | ||
| Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications | Q24608343 | ||
| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
| Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination | Q27676128 | ||
| A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice | Q28000121 | ||
| 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark | Q29465773 | ||
| Mass-spectrometry-based draft of the human proteome | Q29617249 | ||
| A draft map of the human proteome | Q29617250 | ||
| Visualizing spatiotemporal dynamics of multicellular cell-cycle progression | Q29617610 | ||
| The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage | Q34110993 | ||
| Assembly and function of DNA double-strand break repair foci in mammalian cells | Q34146952 | ||
| The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. | Q34226618 | ||
| A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure | Q34270749 | ||
| The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination | Q34309225 | ||
| RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1. | Q34366919 | ||
| RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci | Q34762756 | ||
| The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection | Q34787446 | ||
| Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection | Q34980915 | ||
| Critical roles of ring finger protein RNF8 in replication stress responses | Q35063105 | ||
| Fine-tuning of DNA damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice | Q35100350 | ||
| RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1 | Q36418906 | ||
| Regulation of DNA repair by ubiquitylation | Q36457732 | ||
| MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination | Q36648222 | ||
| Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage | Q36696336 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ubiquitination | Q33059483 |
| P304 | page(s) | 6919-6933 | |
| P577 | publication date | 2015-06-22 | |
| P1433 | published in | Nucleic Acids Research | Q135122 |
| P1476 | title | The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80 | |
| P478 | volume | 43 |
| Q37669871 | A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation. |
| Q42221274 | Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4. |
| Q39730889 | Functional Analysis of Missense Variants in the Putative Breast Cancer Susceptibility Gene XRCC2. |
| Q91761588 | Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status |
| Q40116814 | Mutations in the 'Fingers' subdomain of the deubiquitinase USP1 modulate its function and activity |
| Q33801982 | Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibition |
| Q37745139 | Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor |
| Q92608468 | RAP80 and BRCA1 PARsylation protect chromosome integrity by preventing retention of BRCA1-B/C complexes in DNA repair foci |
| Q39417081 | RAP80, ubiquitin and SUMO in the DNA damage response. |
| Q56221440 | RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair |
| Q26773800 | Role of Deubiquitinating Enzymes in DNA Repair |
| Q93114616 | Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation |
| Q57801762 | TGF-β signaling pathway mediated by deubiquitinating enzymes |
| Q52369363 | The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair. |
| Q64288182 | The role of ubiquitin-specific peptidases in cancer progression |
| Q38799026 | The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2. |
| Q64109748 | The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency |
| Q36771950 | Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo |
| Q64389276 | USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination |
| Q33625848 | USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7 |
| Q93052576 | USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination |
| Q28771759 | USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication |
| Q90262076 | Usp26 mutation in mice leads to defective spermatogenesis depending on genetic background |
| Q26742134 | Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair |
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