| scholarly article | Q13442814 |
| P2093 | author name string | Fan Zhang | |
| Paul R Andreassen | |||
| Jung-Young Park | |||
| Gregory Bick | |||
| P2860 | cites work | MDC1 is a mediator of the mammalian DNA damage checkpoint | Q24296229 |
| The BRCT Domain Is a Phospho-Protein Binding Domain | Q24298428 | ||
| MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks | Q24299852 | ||
| RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
| RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
| Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. | Q24301052 | ||
| Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response | Q24306765 | ||
| RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites | Q24306789 | ||
| Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response | Q24306807 | ||
| DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains | Q24306945 | ||
| Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair. | Q40028909 | ||
| CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response | Q40104298 | ||
| Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation | Q40798697 | ||
| A recurrent mutation in PALB2 in Finnish cancer families. | Q55043120 | ||
| Germline RAP80 mutations and susceptibility to breast cancer | Q80787762 | ||
| Structural basis for recruitment of BRCA2 by PALB2 | Q24315745 | ||
| PALB2 is an integral component of the BRCA complex required for homologous recombination repair | Q24316113 | ||
| BRCA1 supports XIST RNA concentration on the inactive X chromosome | Q24316340 | ||
| CCDC98 targets BRCA1 to DNA damage sites | Q24321418 | ||
| PALB2 regulates recombinational repair through chromatin association and oligomerization | Q24322952 | ||
| PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene | Q24615080 | ||
| Human CtIP promotes DNA end resection | Q24646062 | ||
| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
| Genetic analysis of BRCA1 function in a defined tumor cell line | Q28142643 | ||
| Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control | Q28213030 | ||
| RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors | Q28253705 | ||
| Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis | Q28274000 | ||
| The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression | Q28282486 | ||
| Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination | Q28294199 | ||
| Histone ubiquitination associates with BRCA1-dependent DNA damage response | Q28506770 | ||
| MDC1 interacts with Rad51 and facilitates homologous recombination | Q34454221 | ||
| Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. | Q34541051 | ||
| Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer | Q34597168 | ||
| Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. | Q34597176 | ||
| RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci | Q34762756 | ||
| The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection | Q34787446 | ||
| Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis. UKCCCR Familial Ovarian Cancer Study Group. | Q35881529 | ||
| E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks | Q37016395 | ||
| The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM | Q37175369 | ||
| Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function | Q37217527 | ||
| RAD18 transmits DNA damage signalling to elicit homologous recombination repair | Q37344711 | ||
| PALB2 links BRCA1 and BRCA2 in the DNA-damage response | Q37361223 | ||
| BRCA1 and its toolbox for the maintenance of genome integrity | Q37507563 | ||
| BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity | Q37524847 | ||
| FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses. | Q39672854 | ||
| Differential modulation of BRCA1 and BARD1 nuclear localisation and foci assembly by DNA damage | Q39792758 | ||
| PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. | Q39827885 | ||
| P433 | issue | Pt 24 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6049-6057 | |
| P577 | publication date | 2012-10-04 | |
| P1433 | published in | Journal of Cell Science | Q1524177 |
| P1476 | title | MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination | |
| P478 | volume | 125 |
| Q37669871 | A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation. |
| Q38813207 | A mechanism for the suppression of homologous recombination in G1 cells |
| Q86044072 | A novel ruthenium(II)-polypyridyl complex inhibits cell proliferation and induces cell apoptosis by impairing DNA damage repair |
| Q56978702 | Antiparallel Coiled-Coil Interactions Mediate Homodimerization of the DNA Damage Repair Protein, PALB2 |
| Q33731257 | BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis |
| Q36945848 | BRCA1 in the DNA damage response and at telomeres |
| Q51713162 | Coordination of the recruitment of the FANCD2 and PALB2 Fanconi anemia proteins by an ubiquitin signaling network. |
| Q36343157 | Differential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms |
| Q37393820 | Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications |
| Q35106767 | Growing recognition of the role for rare missense substitutions in breast cancer susceptibility |
| Q37213329 | Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage |
| Q34107377 | Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice |
| Q92627355 | PALB2 (partner and localizer of BRCA2) |
| Q28243398 | PALB2: the hub of a network of tumor suppressors involved in DNA damage responses |
| Q36496577 | RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids. |
| Q35358319 | Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair |
| Q99634411 | Roles for MDC1 in cancer development and treatment |
| Q92643741 | The Functions of DNA Damage Factor RNF8 in the Pathogenesis and Progression of Cancer |
| Q38860961 | The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80. |
| Q101477855 | The p.Ser64Leu and p,Pro104Leu missense variants of PALB2 identified in familial pancreatic cancer patients compromise the DNA damage response |
| Q89768702 | Ubiquitin and ubiquitin-like molecules in DNA double strand break repair |
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