scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1047675721 |
P356 | DOI | 10.1038/NSMB1067 |
P3181 | OpenCitations bibliographic resource ID | 849574 |
P698 | PubMed publication ID | 16474402 |
P5875 | ResearchGate publication ID | 7303046 |
P50 | author | Cheryl Arrowsmith | Q5092682 |
Vivian Saridakis | Q29515228 | ||
Feroz Sarkari | Q29515229 | ||
P2093 | author name string | Lori Frappier | |
Yi Sheng | |||
Shili Duan | |||
Tianne Wu | |||
P2860 | cites work | Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization | Q24292930 |
Distinct molecular mechanism for initiating TRAF6 signalling | Q24302174 | ||
Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2 | Q24303581 | ||
A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein | Q24532134 | ||
Improved methods for building protein models in electron density maps and the location of errors in these models | Q26776980 | ||
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
The structural basis for the recognition of diverse receptor sequences by TRAF2 | Q27619945 | ||
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde | Q27640257 | ||
Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP | Q28204725 | ||
Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization | Q28243346 | ||
A dynamic role of HAUSP in the p53-Mdm2 pathway | Q28253645 | ||
Tumour suppression: disruption of HAUSP gene stabilizes p53 | Q28254102 | ||
Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. | Q30941966 | ||
Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation | Q39540070 | ||
Herpes simplex virus type 1 immediate-early protein Vmw110 binds strongly and specifically to a 135-kDa cellular protein | Q45778575 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 285-91 | |
P577 | publication date | 2006-03-01 | |
P1433 | published in | Nature Structural & Molecular Biology | Q1071739 |
P1476 | title | Molecular recognition of p53 and MDM2 by USP7/HAUSP | |
P478 | volume | 13 |
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Q35489050 | A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses |
Q35563921 | Annexin-1 regulated by HAUSP is essential for UV-induced damage response |
Q49312110 | BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage |
Q80037402 | Balancing Mdm2 - a Daxx-HAUSP matter |
Q27675410 | Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein |
Q42917799 | C-terminal region of USP7/HAUSP is critical for deubiquitination activity and contains a second mdm2/p53 binding site |
Q35665976 | Changes in the nasopharyngeal carcinoma nuclear proteome induced by the EBNA1 protein of Epstein-Barr virus reveal potential roles for EBNA1 in metastasis and oxidative stress responses |
Q35058051 | Characterization of RanBPM molecular determinants that control its subcellular localization |
Q27003831 | Contributions of Epstein-Barr nuclear antigen 1 (EBNA1) to cell immortalization and survival |
Q28547943 | Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7 |
Q38336126 | DUBs, the regulation of cell identity and disease |
Q40632330 | Damaged replication forks tolerate USP7 to maintain genome stability |
Q50316561 | Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis |
Q38326071 | Deubiquitinases and the new therapeutic opportunities offered to cancer |
Q36732782 | Deubiquitination in virus infection |
Q30415089 | Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway |
Q41838441 | Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells |
Q21284381 | Deubiquitylating enzymes and disease |
Q27329642 | Deubiquitylation machinery is required for embryonic polarity in Caenorhabditis elegans |
Q35071233 | Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage. |
Q58103951 | Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11 |
Q38597231 | EBNA1. |
Q52593708 | EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers. |
Q33373662 | Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies |
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Q36852277 | From bortezomib to other inhibitors of the proteasome and beyond |
Q27316805 | Functional diversity and structural disorder in the human ubiquitination pathway |
Q79168398 | HAUSP hunting the FOX(O) |
Q35913537 | HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response |
Q36105979 | HSV ICP0 recruits USP7 to modulate TLR-mediated innate response |
Q58116151 | Identification and Characterization of USP7 Targets in Cancer Cells |
Q38801652 | Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7. |
Q53499450 | Identification of survival-related genes of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma multiforme. |
Q92643626 | In silico evidence of de novo interactions between ribosomal and Epstein - Barr virus proteins |
Q38240374 | Insight in the multilevel regulation of NER. |
Q51765390 | Insights into the ubiquitin-proteasome system of human embryonic stem cells. |
Q60907800 | Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity |
Q42286181 | Linear motifs confer functional diversity onto splice variants |
Q36977443 | MDM2 E3 ubiquitin ligase mediates UT-A1 urea transporter ubiquitination and degradation |
Q36094618 | MDM2 and MDM4: p53 regulators as targets in anticancer therapy |
Q38149734 | MDM2's social network |
Q38934480 | Manipulation of ubiquitin/SUMO pathways in human herpesviruses infection |
Q28075457 | Modulation of the p53/MDM2 interplay by HAUSP inhibitors |
Q27646751 | Molecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating Enzyme |
Q57821066 | Molecular dynamics simulation reveals the possible druggable of USP7 |
Q42602861 | Molecular mechanism for the substrate recognition of USP7. |
Q90532816 | Molecular mimicry, genetic homology, and gene sharing proteomic "molecular fingerprints" using an EBV (Epstein-Barr virus)-derived microarray as a potential diagnostic method in autoimmune disease |
Q26775592 | Motif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulation |
Q92529034 | Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in disease |
Q38970691 | Nucleotide Excision Repair: Finely Tuned Molecular Orchestra of Early Pre-incision Events |
Q90410218 | OTUD4: A Potential Prognosis Biomarker for Multiple Human Cancers |
Q41906667 | On the intrinsic disorder status of the major players in programmed cell death pathways |
Q64449404 | PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359 |
Q64268630 | Preferential digestion of PCNA-ubiquitin and p53-ubiquitin linkages by USP7 to remove polyubiquitin chains from substrates |
Q35212637 | Reduced association of anti-apoptotic protein Mcl-1 with E3 ligase Mule increases the stability of Mcl-1 in breast cancer cells |
Q24645701 | Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes |
Q45316786 | Regulation of TP53 Degradation |
Q35161624 | Regulation of the DNA damage response by ubiquitin conjugation |
Q37112275 | Reverse the curse--the role of deubiquitination in cell cycle control |
Q41952089 | Role of deubiquitylase HAUSP in stem cell maintenance |
Q34579190 | SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization |
Q36544196 | STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation |
Q90505741 | Small molecules that target the ubiquitin system |
Q41992139 | Stabilization of Ultraviolet (UV)-stimulated Scaffold Protein A by Interaction with Ubiquitin-specific Peptidase 7 Is Essential for Transcription-coupled Nucleotide Excision Repair |
Q38847962 | Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1. |
Q36567780 | Structural aspects of recently discovered viral deubiquitinating activities |
Q80100153 | Structural basis of ubiquitin recognition by the deubiquitinating protease USP2 |
Q27683231 | Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains |
Q33721242 | TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability |
Q99248754 | TRIM37 controls cancer-specific vulnerability to PLK4 inhibition |
Q92002855 | Targeting USP7-Mediated Deubiquitination of MDM2/MDMX-p53 Pathway for Cancer Therapy: Are We There Yet? |
Q37323654 | The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth |
Q38166365 | The Epstein-Barr Virus EBNA1 Protein |
Q37702220 | The ISG15-specific protease USP18 regulates stability of PTEN. |
Q26744520 | The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers |
Q27932371 | The Ubp15 deubiquitinase promotes timely entry into S phase in Saccharomyces cerevisiae |
Q24296502 | The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 |
Q96431846 | The deubiquitylase UCHL3 maintains cancer stem-like properties by stabilizing the aryl hydrocarbon receptor |
Q37517626 | The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics |
Q33815705 | The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies |
Q33720055 | The molecular determinants for distinguishing between ubiquitin and NEDD8 by USP2. |
Q43118033 | The p53--Mdm2--HAUSP complex is involved in p53 stabilization by HAUSP. |
Q28267230 | The role of UBL domains in ubiquitin-specific proteases |
Q28118567 | The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7 |
Q37143739 | The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X |
Q36086767 | The ubiquitin-specific protease USP7 modulates the replication of Kaposi's sarcoma-associated herpesvirus latent episomal DNA |
Q37591937 | Tumour suppression by p53: a role for the DNA damage response? |
Q24296967 | USP10 regulates p53 localization and stability by deubiquitinating p53 |
Q24328791 | USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity |
Q36126977 | USP2a protein deubiquitinates and stabilizes the circadian protein CRY1 in response to inflammatory signals |
Q85682295 | USP37 directly deubiquitinates and stabilizes c-Myc in lung cancer |
Q28607464 | USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder |
Q36944526 | USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation |
Q98771728 | USP7 Is a Master Regulator of Genome Stability |
Q47149840 | USP7 Is a Tumor-Specific WNT Activator for APC-Mutated Colorectal Cancer by Mediating β-Catenin Deubiquitination |
Q63246433 | USP7 Regulates Cytokinesis through FBXO38 and KIF20B |
Q38918184 | USP7 cooperates with SCML2 to regulate the activity of PRC1. |
Q50290334 | USP7 deubiquitinates MDM2 |
Q50290335 | USP7 deubiquitinates TP53 and counteracts MDM2 |
Q90100499 | USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin |
Q38876635 | USP7 is essential for maintaining Rad18 stability and DNA damage tolerance. |
Q96828977 | USP7 manipulation by viral proteins |
Q35221054 | USP7 overexpression predicts a poor prognosis in lung squamous cell carcinoma and large cell carcinoma |
Q89737230 | USP7 stabilizes EZH2 and enhances cancer malignant progression |
Q33707419 | USP7/HAUSP Promotes the Sequence-Specific DNA Binding Activity of p53 |
Q64079043 | USP7: Novel Drug Target in Cancer Therapy |
Q91936479 | USP7: Structure, substrate specificity, and inhibition |
Q30429637 | Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. |
Q59351757 | Ubiquitination at the interface of tumor viruses and DNA damage responses |
Q33815907 | WDR79 promotes the proliferation of non-small cell lung cancer cells via USP7-mediated regulation of the Mdm2-p53 pathway |
Q28079390 | p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum Concept |
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