scholarly article | Q13442814 |
P50 | author | Jae Kim | Q42798668 |
P2093 | author name string | Yehia Daaka | |
Nicole Frilot | |||
Vijayabaskar Lakshmikanthan | |||
P2860 | cites work | Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes | Q22008730 |
PTP1B contributes to the oncogenic properties of colon cancer cells through Src activation | Q24299152 | ||
Celecoxib for the prevention of colorectal adenomatous polyps | Q28200375 | ||
Prostaglandin E synthase | Q28214892 | ||
Cyclooxygenases 1 and 2 | Q29615645 | ||
Role of cAMP in the promotion of colorectal cancer cell growth by prostaglandin E2. | Q30855607 | ||
Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells | Q33356757 | ||
Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis. | Q34108525 | ||
Role of beta-arrestin 1 in the metastatic progression of colorectal cancer | Q34335080 | ||
Coxibs and cardiovascular disease | Q34356732 | ||
Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. | Q34536660 | ||
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor | Q34548751 | ||
beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor | Q34562493 | ||
Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas | Q34570463 | ||
Targeting the mitogen-activated protein kinase cascade to treat cancer | Q35968411 | ||
Stop that cell! Beta-arrestin-dependent chemotaxis: a tale of localized actin assembly and receptor desensitization | Q36604354 | ||
NSAIDs and cancer prevention: targets downstream of COX-2. | Q36651702 | ||
Cyclooxygenases, prostanoids, and tumor progression | Q36925833 | ||
Lipid signalling in disease. | Q37064018 | ||
Cyclooxygenase-2 inhibitors in colorectal cancer prevention: point | Q37245575 | ||
The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment | Q37366259 | ||
Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells | Q39840354 | ||
Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2. | Q39876429 | ||
Molecular and pharmacological blockade of the EP4 receptor selectively inhibits both proliferation and invasion of human inflammatory breast cancer cells. | Q39882197 | ||
Prostaglandin E2 stimulates human lung carcinoma cell growth through induction of integrin-linked kinase: the involvement of EP4 and Sp1. | Q39889975 | ||
Soluble EP2 neutralizes prostaglandin E2-induced cell signaling and inhibits osteolytic tumor growth | Q39940114 | ||
The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells | Q40107119 | ||
Src family kinase activity regulates adhesion, spreading and migration of pancreatic endocrine tumour cells. | Q40151992 | ||
Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism | Q40223997 | ||
Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence | Q40304135 | ||
Erythropoietin promotes MCF-7 breast cancer cell migration by an ERK/mitogen-activated protein kinase-dependent pathway and is primarily responsible for the increase in migration observed in hypoxia | Q40365100 | ||
Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. | Q40396797 | ||
Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPAR(gamma) agonists: evidence for disparate functional effects which are independent of NF-(kappa)B and PPAR(gamma). | Q40402766 | ||
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor | Q40646776 | ||
Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer | Q40780797 | ||
Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells | Q42164683 | ||
FDA advisers warn: COX 2 inhibitors increase risk of heart attack and stroke | Q42855511 | ||
Prostaglandin E2 increases growth and motility of colorectal carcinoma cells | Q43559615 | ||
Prostaglandin E2 reinforces the activation of Ras signal pathway in lung adenocarcinoma cells via EP3. | Q43984203 | ||
The relationship between cyclooxygenase-2 expression and colorectal cancer. | Q44193470 | ||
Dimethyl celecoxib as a novel non-cyclooxygenase 2 therapy in the treatment of non-small cell lung cancer | Q46497910 | ||
The ups and downs of SRC regulation: tumor suppression by Cbp. | Q46552286 | ||
Prostaglandin E2 receptor 2 overexpression in squamous cell carcinoma of the lung correlates with p16INK4A methylation and an unfavorable prognosis. | Q51825086 | ||
Cyclooxygenase-2 (COX-2) mRNA expression levels in normal lung tissues and non-small cell lung cancers. | Q53413842 | ||
COX-2 inhibitors, other NSAIDs, and cardiovascular risk: the seduction of common sense. | Q55042437 | ||
Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer | Q77601963 | ||
P433 | issue | 4 | |
P921 | main subject | lung cancer | Q47912 |
prostaglandin E2 | Q416554 | ||
P304 | page(s) | 569-577 | |
P577 | publication date | 2010-03-30 | |
P1433 | published in | Molecular Cancer Research | Q2751014 |
P1476 | title | Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome | |
P478 | volume | 8 |
Q26997809 | 5-methoxyindole metabolites of L-tryptophan: control of COX-2 expression, inflammation and tumorigenesis |
Q47100323 | Activation of PGE2/EP2 and PGE2/EP4 signaling pathways positively regulate the level of PD-1 in infiltrating CD8+ T cells in patients with lung cancer |
Q36003618 | Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA. |
Q33791932 | Alterations in lipid mediated signaling and Wnt/ β -catenin signaling in DMH induced colon cancer on supplementation of fish oil. |
Q39003091 | An EP4 antagonist ONO-AE3-208 suppresses cell invasion, migration, and metastasis of prostate cancer |
Q55239965 | Arachidonic acid-induced Ca2+ entry and migration in a neuroendocrine cancer cell line. |
Q92108851 | Bioinformatics analysis of microarray data to identify the candidate biomarkers of lung adenocarcinoma |
Q51703393 | COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis. |
Q38923338 | CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of β-catenin signaling |
Q33564023 | Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration |
Q100949984 | Common Mechanistic Pathways in Cancer and Heart Failure |
Q57052675 | Cordycepin inhibits lipopolysaccharide-induced cell migration and invasion in human colorectal carcinoma HCT-116 cells through down-regulation of prostaglandin E2 receptor EP4 |
Q35838020 | Cyclooxygenase-2, a Potential Therapeutic Target, Is Regulated by miR-101 in Esophageal Squamous Cell Carcinoma. |
Q34224752 | Cyclooxygenases and lipoxygenases in cancer |
Q40852202 | Cysteinyl leukotriene 1 receptor influences intestinal polyp incidence in a gender-specific manner in the ApcMin/+ mouse model |
Q36335457 | Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E(2) synthesis |
Q60043877 | Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase |
Q36444308 | Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis |
Q36340442 | EP1 disruption attenuates end-organ damage in a mouse model of hypertension |
Q38720995 | EP4 receptor promotes invadopodia and invasion in human breast cancer |
Q40854700 | Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transition |
Q34666257 | Honokiol inhibits non-small cell lung cancer cell migration by targeting PGE₂-mediated activation of β-catenin signaling |
Q90762243 | Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer |
Q35641880 | Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways |
Q99239658 | Inhibition of PI3K-AKT Signaling Blocks PGE2-Induced COX-2 Expression in Lung Adenocarcinoma |
Q38053088 | Involvement of β-arrestins in cancer progression |
Q26850218 | Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention |
Q37046835 | MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2. |
Q38459674 | Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling |
Q37701635 | Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer |
Q35049578 | Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways |
Q43520637 | Nicotine induces EP4 receptor expression in lung carcinoma cells by acting on AP-2α: The intersection between cholinergic and prostanoid signaling |
Q35879417 | Novel link between prostaglandin E2 (PGE2) and cholinergic signaling in lung cancer: The role of c-Jun in PGE2-induced α7 nicotinic acetylcholine receptor expression and tumor cell proliferation |
Q33695021 | Osteolytic bone metastasis is hampered by impinging on the interplay among autophagy, anoikis and ossification |
Q51132517 | PGE2 /EP4 receptor attenuated mucosal injury via β-arrestin1/Src/EGFR-mediated proliferation in portal hypertensive gastropathy. |
Q33761715 | PGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells |
Q37470737 | Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties |
Q37366238 | Prostaglandin E2 (PGE2) promotes proliferation and invasion by enhancing SUMO-1 activity via EP4 receptor in endometrial cancer |
Q36806255 | Prostaglandin E2 EP receptors as therapeutic targets in breast cancer |
Q37908321 | Prostaglandin E2 modulation of blood pressure homeostasis: studies in rodent models |
Q35713568 | Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functions |
Q35311177 | Prostaglandin E2 regulates renal cell carcinoma invasion through the EP4 receptor-Rap GTPase signal transduction pathway |
Q36424854 | Prostaglandin E2 stimulates normal bronchial epithelial cell growth through induction of c-Jun and PDK1, a kinase implicated in oncogenesis |
Q38759898 | Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells |
Q64932507 | Prostaglandin E2 triggers cytochrome P450 17α hydroxylase overexpression via signal transducer and activator of transcription 3 phosphorylation and promotes invasion in endometrial cancer. |
Q38701133 | Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells |
Q50082353 | Prostaglandin receptors induce urothelial tumourigenesis as well as bladder cancer progression and cisplatin resistance presumably via modulating PTEN expression. |
Q39640064 | RETRACTED: Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E2and prostaglandin E2receptors |
Q35871610 | Rap1GAP regulates renal cell carcinoma invasion |
Q38473314 | Regulatory T cells and potential inmmunotherapeutic targets in lung cancer |
Q34055550 | Retracted: Green Tea Catechins Reduce Invasive Potential of Human Melanoma Cells by Targeting COX-2, PGE2 Receptors and Epithelial-to-Mesenchymal Transition |
Q39078274 | Silymarin suppresses the PGE2 -induced cell migration through inhibition of EP2 activation; G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signal pathways |
Q36771000 | TGF-β effects on prostate cancer cell migration and invasion are mediated by PGE2 through activation of PI3K/AKT/mTOR pathway |
Q34400793 | The Prostaglandin E2 Receptor, EP2, Stimulates Keratinocyte Proliferation in Mouse Skin by G Protein-dependent and β-Arrestin1-dependent Signaling Pathways |
Q47328865 | The role and mechanism of β‑arrestins in cancer invasion and metastasis (Review). |
Q36622079 | Timosaponin AIII inhibits melanoma cell migration by suppressing COX-2 and in vivo tumor metastasis |
Q89358557 | Upregulation of Cyclooxygenase-2/Prostaglandin E2 (COX-2/PGE2) Pathway Member Multiple Drug Resistance-Associated Protein 4 (MRP4) and Downregulation of Prostaglandin Transporter (PGT) and 15-Prostaglandin Dehydrogenase (15-PGDH) in Triple-Negative |
Q26740489 | β-arrestin1 at the cross-road of endothelin-1 signaling in cancer |
Q34589698 | βArrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer |
Q33676791 | βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility |
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