| scholarly article | Q13442814 |
| P2093 | author name string | Robert Langenbach | |
| Huei-Chen Lao | |||
| Kyung-Soo Chun | |||
| P2860 | cites work | Cancer Research | Q326097 |
| c-Src-dependent Activation of the Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase Pathway by Arsenic | Q23919500 | ||
| Src family kinases in tumor progression and metastasis | Q24311656 | ||
| Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds | Q24605173 | ||
| Transduction of receptor signals by beta-arrestins | Q28246395 | ||
| Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis | Q28288381 | ||
| Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps | Q28510276 | ||
| beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation | Q28512807 | ||
| Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice | Q28585868 | ||
| Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis | Q28593718 | ||
| Cyclooxygenases: structural, cellular, and molecular biology | Q29616510 | ||
| EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF | Q29619098 | ||
| Mechanism of biological synergy between cellular Src and epidermal growth factor receptor | Q30454480 | ||
| BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells. | Q31938652 | ||
| Regulation of tyrosine kinase cascades by G-protein-coupled receptors. | Q33597362 | ||
| Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome. | Q33794119 | ||
| Beyond desensitization: physiological relevance of arrestin-dependent signaling. | Q33890802 | ||
| Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration. | Q33926315 | ||
| Phosphorylation of inositol 1,4,5-trisphosphate receptors in parotid acinar cells. A mechanism for the synergistic effects of cAMP on Ca2+ signaling | Q34100454 | ||
| Prostanoid receptors: subtypes and signaling | Q34192781 | ||
| Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission | Q34226003 | ||
| Role of beta-arrestin 1 in the metastatic progression of colorectal cancer | Q34335080 | ||
| Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein) | Q34376629 | ||
| The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia | Q34423141 | ||
| Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis | Q34519566 | ||
| Pharmacological PKA inhibition: all may not be what it seems | Q34784583 | ||
| Prostanoid receptors and phosphatidylinositol 3-kinase: a pathway to cancer? | Q35181785 | ||
| EP2 and EP4 prostanoid receptor signaling | Q35579608 | ||
| Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. | Q35951476 | ||
| Cyclooxygenase-2 inhibits UVB-induced apoptosis in mouse skin by activating the prostaglandin E2 receptors, EP2 and EP4. | Q36153789 | ||
| Epidermal growth factor receptor (EGFR) signaling in cancer | Q36353031 | ||
| Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis | Q36869961 | ||
| The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development | Q37329206 | ||
| Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis | Q37486563 | ||
| Diversity in arrestin function | Q37550019 | ||
| Turning off the signal: desensitization of beta-adrenergic receptor function | Q37887325 | ||
| EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways | Q40154550 | ||
| Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. | Q40219633 | ||
| Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy | Q40747279 | ||
| Arrestin specificity for G protein-coupled receptors in human airway smooth muscle | Q40797346 | ||
| Signal characteristics of G protein-transactivated EGF receptor | Q41960343 | ||
| Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis | Q42521538 | ||
| Is cyclooxygenase-2 important in skin carcinogenesis? | Q44042825 | ||
| Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor | Q44375278 | ||
| Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis | Q44826931 | ||
| Not so strange bedfellows: G-protein-coupled receptors and Src family kinases | Q45111099 | ||
| A tail of two src's: mutatis mutandis | Q45248634 | ||
| Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development | Q46757474 | ||
| p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis. | Q46970873 | ||
| Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytes. | Q50950996 | ||
| Prostaglandin receptor EP2 is responsible for cyclooxygenase-2 induction by prostaglandin E2 in mouse skin. | Q53337201 | ||
| Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor. | Q53358434 | ||
| Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development. | Q53599778 | ||
| Regulation of vascular endothelial cell growth factor expression in mouse mammary tumor cells by the EP2 subtype of the prostaglandin E2 receptor | Q64378573 | ||
| Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding | Q73720739 | ||
| P433 | issue | 51 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | prostaglandin E2 | Q416554 |
| keratinocyte | Q1473931 | ||
| P304 | page(s) | 39672-39681 | |
| P577 | publication date | 2010-10-19 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and {beta}-arrestin1-dependent signaling pathways | |
| The Prostaglandin E2 Receptor, EP2, Stimulates Keratinocyte Proliferation in Mouse Skin by G Protein-dependent and β-Arrestin1-dependent Signaling Pathways | |||
| P478 | volume | 285 |
| Q24299872 | Aldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitis |
| Q38966225 | Discovery of G Protein-Biased EP2 Receptor Agonists. |
| Q36340442 | EP1 disruption attenuates end-organ damage in a mouse model of hypertension |
| Q54527752 | Extracts from Radix Astragali and Radix Rehmanniae promote keratinocyte proliferation by regulating expression of growth factor receptors. |
| Q40515231 | Fungal pattern receptors down-regulate the inflammatory response by a cross-inhibitory mechanism independent of interleukin-10 production |
| Q35225804 | Impact of EPA ingestion on COX- and LOX-mediated eicosanoid synthesis in skin with and without a pro-inflammatory UVR challenge--report of a randomised controlled study in humans |
| Q47776294 | Mechanotransduction signaling in podocytes from fluid flow shear stress |
| Q51132517 | PGE2 /EP4 receptor attenuated mucosal injury via β-arrestin1/Src/EGFR-mediated proliferation in portal hypertensive gastropathy. |
| Q35185824 | PGE2 Inhibits IL-10 Production via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition |
| Q37461919 | Prostaglandin E2 blocks menadione-induced apoptosis through the Ras/Raf/Erk signaling pathway in promonocytic leukemia cell lines |
| Q47351317 | Prostaglandin E2 in the Regulation of Water Transport in Renal Collecting Ducts |
| Q37908321 | Prostaglandin E2 modulation of blood pressure homeostasis: studies in rodent models |
| Q33651797 | Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection |
| Q36573214 | Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation. |
| Q39078274 | Silymarin suppresses the PGE2 -induced cell migration through inhibition of EP2 activation; G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signal pathways |
| Q38171193 | Strategies targeting cAMP signaling in the treatment of polycystic kidney disease |
| Q53666709 | Transactivation of EGFR by prostaglandin E2 receptors: a nuclear story? |
| Q34306004 | Transactivation of epidermal growth factor receptor through platelet-activating factor/receptor in ovarian cancer cells |
| Q36763148 | cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse |
| Q38710607 | β-Arrestin 1 has an essential role in neurokinin-1 receptor-mediated glioblastoma cell proliferation and G2/M phase transition |
| Q87374064 | β-arrestin 2 inhibits proinflammatory chemokine production and attenuates contact allergic inflammation in the skin |
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