scholarly article | Q13442814 |
P50 | author | Paul Greengard | Q309979 |
Eric J. Nestler | Q5386788 | ||
Rachael L. Neve | Q108917624 | ||
P2093 | author name string | Sumana Chakravarty | |
Venetia Zachariou | |||
Lakshmi A. Devi | |||
Ivone Gomes | |||
Kassi Psifogeorgou | |||
Patrick B. Allen | |||
Joanna J. Charlton | |||
P2860 | cites work | Mu opioid receptor: a gateway to drug addiction | Q35803141 |
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Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors | Q40442171 | ||
Spinophilin stabilizes cell surface expression of alpha 2B-adrenergic receptors | Q40648991 | ||
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Separation of mu-opioid receptor desensitization and internalization: endogenous receptors in primary neuronal cultures. | Q44330114 | ||
Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity | Q44339547 | ||
Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons. | Q44341663 | ||
Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery | Q44345837 | ||
Adenylyl cyclase superactivation induced by long-term treatment with opioid agonist is dependent on receptor localized within lipid rafts and is independent of receptor internalization | Q44351622 | ||
Brain region-specific mechanisms for acute morphine-induced mitogen-activated protein kinase modulation and distinct patterns of activation during analgesic tolerance and locomotor sensitization. | Q44580806 | ||
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Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia. | Q44804066 | ||
In vivo regulation of extracellular signal-regulated protein kinase (ERK) and protein kinase B (Akt) phosphorylation by acute and chronic morphine | Q44824322 | ||
Neuroscience of addiction | Q44880443 | ||
An essential role for DeltaFosB in the nucleus accumbens in morphine action | Q46896171 | ||
Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses | Q48445440 | ||
Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity | Q48590755 | ||
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines | Q24641883 | ||
Essential role for RGS9 in opiate action | Q24655663 | ||
Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5 | Q24670878 | ||
Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton | Q24685127 | ||
Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein | Q28138646 | ||
Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1 | Q28140793 | ||
RGS9-2 is a negative modulator of mu-opioid receptor function | Q28242513 | ||
Enhanced morphine analgesia in mice lacking beta-arrestin 2 | Q28504554 | ||
Spinophilin regulates the formation and function of dendritic spines | Q28513720 | ||
Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons | Q28575335 | ||
The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits | Q28582944 | ||
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors | Q28584983 | ||
Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence | Q28590279 | ||
Molecular basis of long-term plasticity underlying addiction | Q29620539 | ||
Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action | Q30477757 | ||
Regulation of opioid receptor activities | Q33601320 | ||
Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. | Q33873664 | ||
Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin | Q33931039 | ||
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli | Q34038682 | ||
Drug addictions. Molecular and cellular endpoints. | Q34310836 | ||
Molecular and cellular basis of addiction | Q34440561 | ||
Inhibition of ERK pathway or protein synthesis during reexposure to drugs of abuse erases previously learned place preference | Q34479672 | ||
Neural systems underlying opiate addiction. | Q34616139 | ||
Clinical pharmacology of opioids for pain | Q35024267 | ||
G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal | Q35046020 | ||
Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs | Q35172820 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | opioid | Q427523 |
Protein phosphatase 1, regulatory subunit 9B | Q21985869 | ||
P304 | page(s) | 238–247 | |
P577 | publication date | 2008-04-24 | |
P1433 | published in | Neuron | Q3338676 |
P1476 | title | Multiple actions of spinophilin regulate mu opioid receptor function | |
P478 | volume | 58 |
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Q37919731 | Control of striatal signaling by g protein regulators |
Q35205782 | Effect of KEPI (Ppp1r14c) deletion on morphine analgesia and tolerance in mice of different genetic backgrounds: when a knockout is near a relevant quantitative trait locus |
Q34051639 | Enhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptor |
Q24302002 | Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence |
Q37103755 | Knockout of spinophilin, an endogenous antagonist of arrestin-dependent alpha2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences. |
Q37132059 | Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells |
Q36025329 | Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons |
Q35513856 | Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors |
Q37419004 | Membrane functional organisation and dynamic of mu-opioid receptors |
Q38459674 | Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling |
Q37410471 | Modulation of opioid receptor function by protein-protein interactions |
Q36974487 | Molecular mechanisms of opioid receptor-dependent signaling and behavior |
Q33619345 | Mu-opioid receptors transiently activate the Akt-nNOS pathway to produce sustained potentiation of PKC-mediated NMDAR-CaMKII signaling |
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Q36335668 | Neuroplasticity, axonal guidance and micro-RNA genes are associated with morphine self-administration behavior |
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Q38521179 | Postendocytic Sorting of Adrenergic and Opioid Receptors: New Mechanisms and Functions. |
Q48329853 | Protein phosphatase 1γ isoforms linked interactions in the brain |
Q36763815 | Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection |
Q35760250 | R7BP modulates opiate analgesia and tolerance but not withdrawal |
Q91900172 | RGS4 Maintains Chronic Pain Symptoms in Rodent Models |
Q39027669 | RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States |
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Q24632848 | RGS9-2: probing an intracellular modulator of behavior as a drug target |
Q34145295 | Rapid delivery of internalized signaling receptors to the somatodendritic surface by sequence-specific local insertion |
Q30010478 | Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins |
Q37719125 | Regulation of opioid receptors by endocytic membrane traffic: mechanisms and translational implications |
Q36591603 | Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. |
Q37726382 | Regulators of G protein signaling in neuropsychiatric disorders |
Q37726354 | Regulators of G protein signaling proteins as central components of G protein-coupled receptor signaling complexes |
Q41046084 | Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity |
Q36252363 | Spinophilin as a novel regulator of M3 muscarinic receptor-mediated insulin release in vitro and in vivo |
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Q44348688 | The histidine triad nucleotide-binding protein 1 supports mu-opioid receptor-glutamate NMDA receptor cross-regulation |
Q35046317 | Using the Phenogen website for 'in silico' analysis of morphine-induced analgesia: identifying candidate genes. |
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