Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton

scientific article

Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1998PNAS...95.8351B
P356DOI10.1073/PNAS.95.14.8351
P8608Fatcat IDrelease_imcshuphi5fy3o7v4hvq546g2a
P932PMC publication ID20979
P698PubMed publication ID9653190
P5875ResearchGate publication ID235613090

P50authorSolomon Halbert SnyderQ1681665
David M. SabatiniQ16231524
P2093author name stringI A Qureshi
M M Lai
A F Burnett
S Blackshaw
P E Burnett
P2860cites workA huntingtin-associated protein enriched in brain with implications for pathologyQ24303499
Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formationQ24678330
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1Q24682697
Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZQ27732927
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinasesQ28187456
A mammalian protein targeted by G1-arresting rapamycin-receptor complexQ28243712
Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of JunQ28283776
RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORsQ28286431
Recognition of unique carboxyl-terminal motifs by distinct PDZ domainsQ29547580
Getting the message from the gene to the synapse: sorting and intracellular transport of RNA in neuronsQ30311413
Structural and functional analysis of pp70S6kQ33716466
Transformation of mammalian cells with genes from procaryotes and eucaryotesQ34030262
Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory gangliaQ35160653
Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA familyQ35234179
4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinaseQ37628904
Making the connection: Cytoskeletal rearrangements during growth cone guidanceQ40430559
The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.Q40789796
Regulation of translation elongation factor-2 by insulin via a rapamycin-sensitive signalling pathwayQ41064925
A signaling pathway to translational controlQ41073792
p70 S6 kinase: an enigma with variationsQ41166805
Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expressionQ41436483
Neural actions of immunophilin ligands.Q41724530
Differential immunohistochemical localization of inositol 1,4,5-trisphosphate- and ryanodine-sensitive Ca2+ release channels in rat brain.Q48253724
Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing functionQ48617281
Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin AQ73206046
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
P304page(s)8351-6
P577publication date1998-07-07
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleNeurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton
P478volume95

Reverse relations

cites work (P2860)
Q33898132A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
Q36923103Angiotensin IV upregulates the activity of protein phosphatase 1α in Neura-2A cells
Q28138646Association of the D2 dopamine receptor third cytoplasmic loop with spinophilin, a protein phosphatase-1-interacting protein
Q33703262Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade
Q28576201Brain actin-associated protein phosphatase 1 holoenzymes containing spinophilin, neurabin, and selected catalytic subunit isoforms
Q73704465Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway
Q27939243Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity
Q34007488Cellular function of p70S6K: a role in regulating cell motility
Q24300836Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I
Q28144601Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt
Q35860823Cyclin-dependent Kinase 5 (Cdk5)-dependent Phosphorylation of p70 Ribosomal S6 Kinase 1 (S6K) Is Required for Dendritic Spine Morphogenesis.
Q36168887Development of monoclonal antibodies specific to ribosomal protein S6 kinase 2.
Q28145652Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin
Q58796473Distinct CED-10/Rac1 domains confer context-specific functions in development
Q89697546Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer
Q37110666E4orf1 limits the oncolytic potential of the E1B-55K deletion mutant adenovirus
Q44778310Effective Attenuation of Adenosine A1R Signaling by Neurabin Requires Oligomerization of Neurabin
Q28570143GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation
Q36191624Heptaspanning membrane receptors and cytoskeletal/scaffolding proteins: focus on adenosine, dopamine, and metabotropic glutamate receptor function
Q33883037Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach
Q77206295Immunophilins in the nervous system
Q28565993In vivo dynamics of the F-actin-binding protein neurabin-II
Q90682991Interactions between sleep disruption, motor learning, and p70 S6 kinase 1 signaling
Q34141952Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo.
Q38639597Locus Mapping, Molecular Cloning, and Expression Analysis of rps6kb2, a Novel Metamorphosis-Related Gene in Chinese Tongue Sole (Cynoglossus semilaevis).
Q77694411Making proteins at the synapse: activity-regulated translation and CPEB
Q28137993Molecular insights into mRNA transport and local translation in the mammalian nervous system
Q28512764Multiple actions of spinophilin regulate mu opioid receptor function
Q28564753Nerve growth factor specifically stimulates translation of eukaryotic elongation factor 1A-1 (eEF1A-1) mRNA by recruitment to polyribosomes in PC12 cells
Q41775962Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine.
Q33768516Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation
Q28256601Nuclear export of S6K1 II is regulated by protein kinase CK2 phosphorylation at Ser-17
Q28215948Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region
Q28565058Phosphorylation of spinophilin modulates its interaction with actin filaments
Q24290689Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N
Q33745346Postsynaptic actin and neuronal plasticity
Q24540893Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.
Q23918164Protein phosphorylation cascades associated with methamphetamine-induced glial activation
Q24306984Rac3-induced neuritogenesis requires binding to Neurabin I
Q28202260Rapamycin-sensitive signalling in long-term consolidation of auditory cortex-dependent memory
Q34497326Regulated gene expression in gene therapy.
Q34016103Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1.
Q35828056Regulation of alpha2AR trafficking and signaling by interacting proteins
Q34171088Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin
Q42523266Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity.
Q35876634Revealing Different Roles of the mTOR-Targets S6K1 and S6K2 in Breast Cancer by Expression Profiling and Structural Analysis
Q34297126Roles of serine/threonine phosphatases in hippocampal synaptic plasticity.
Q39169842S6 kinase 2 is bound to chromatin-nuclear matrix cellular fractions and is able to phosphorylate histone H3 at threonine 45 in vitro and in vivo.
Q35514245S6 kinase localizes to the presynaptic active zone and functions with PDK1 to control synapse development
Q24603083S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
Q28576940Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin
Q31840708Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes.
Q28297621Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism
Q28513720Spinophilin regulates the formation and function of dendritic spines
Q28582470Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2
Q22009443Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition
Q34082551Structure-function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin
Q24537519Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology
Q28594950The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology
Q34149414The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines
Q28142953The calcineurin-binding protein cain is a negative regulator of synaptic vesicle endocytosis
Q33873071The calcineurin-dynamin 1 complex as a calcium sensor for synaptic vesicle endocytosis
Q28582944The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits
Q44163338The neuronal choline transporter CHT1 is regulated by immunosuppressor-sensitive pathways
Q35785906The role of protein phosphatase-1 in the modulation of synaptic and structural plasticity
Q28394155There is more than one way to model an elephant. Experiment-driven modeling of the actin cytoskeleton
Q37058649Transcriptomic and genetic studies identify NFAT5 as a candidate gene for cocaine dependence

Search more.