| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Eleni Nikolakaki | |
| Thomas Giannakouros | |||
| Ilias Mylonis | |||
| Eleni Georgatsou | |||
| P2860 | cites work | The protamine family of sperm nuclear proteins | Q21092865 |
| The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation | Q22001546 | ||
| The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs) | Q22009160 | ||
| Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation | Q22010542 | ||
| Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues | Q24290526 | ||
| Cloning and characterization of an alternatively spliced form of SR protein kinase 1 that interacts specifically with scaffold attachment factor-B | Q24291570 | ||
| ASAP, a novel protein complex involved in RNA processing and apoptosis | Q24298844 | ||
| The E1circumflexE4 protein of human papillomavirus interacts with the serine-arginine-specific protein kinase SRPK1 | Q24300233 | ||
| SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells | Q24311443 | ||
| Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons | Q24313181 | ||
| Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway | Q24316154 | ||
| A serine/arginine-rich domain in the human U1 70k protein is necessary and sufficient for ASF/SF2 binding | Q47760992 | ||
| The inner nuclear membrane protein lamin B receptor forms distinct microdomains and links epigenetically marked chromatin to the nuclear envelope. | Q47843681 | ||
| A novel Physarum polycephalum SR protein kinase specifically phosphorylates the RS domain of the human SR protein, ASF/SF2. | Q48068709 | ||
| Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing. | Q54571607 | ||
| Distinct functions of SR proteins in alternative pre-mRNA splicing. | Q55066190 | ||
| Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases | Q59198316 | ||
| Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT | Q64462274 | ||
| A nuclear envelope-associated kinase phosphorylates arginine-serine motifs and modulates interactions between the lamin B receptor and other nuclear proteins | Q71070162 | ||
| Phosphorylation of human sperm protamines HP1 and HP2: identification of phosphorylation sites | Q72552090 | ||
| Mitotic phosphorylation of the lamin B receptor by a serine/arginine kinase and p34(cdc2) | Q73101171 | ||
| Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas | Q79856279 | ||
| Involvement of SR proteins in mRNA surveillance | Q81013881 | ||
| A serine kinase regulates intracellular localization of splicing factors in the cell cycle | Q24317050 | ||
| Serine/arginine protein-specific kinase 2 promotes leukemia cell proliferation by phosphorylating acinus and regulating cyclin A1 | Q24322092 | ||
| The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 | Q24324040 | ||
| The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1. | Q24534118 | ||
| Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor | Q24548056 | ||
| SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1 | Q24548842 | ||
| The inner nuclear membrane: simple, or very complex? | Q24550906 | ||
| Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors | Q24555114 | ||
| Transportin-SR2 mediates nuclear import of phosphorylated SR proteins | Q24555219 | ||
| A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization | Q24622627 | ||
| A quantitative atlas of mitotic phosphorylation | Q24646817 | ||
| Identification of SRPK1 and SRPK2 as the major cellular protein kinases phosphorylating hepatitis B virus core protein | Q24673603 | ||
| Negative regulation of active zone assembly by a newly identified SR protein kinase | Q27329180 | ||
| The structure of Sky1p reveals a novel mechanism for constitutive activity | Q27629551 | ||
| SR protein kinase 1 is resilient to inactivation | Q27643535 | ||
| A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis | Q27860471 | ||
| Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | Q27864128 | ||
| Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4. | Q27930833 | ||
| Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation. | Q27932171 | ||
| Conserved SR protein kinase functions in nuclear import and its action is counteracted by arginine methylation in Saccharomyces cerevisiae | Q27932459 | ||
| Conservation in budding yeast of a kinase specific for SR splicing factors | Q27935651 | ||
| p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation | Q27935814 | ||
| Screening for modulators of spermine tolerance identifies Sky1, the SR protein kinase of Saccharomyces cerevisiae, as a regulator of polyamine transport and ion homeostasis | Q27937203 | ||
| SRPK1 and LBR protein kinases show identical substrate specificities | Q28137892 | ||
| Localization of serine kinases, SRPK1 (SFRSK1) and SRPK2 (SFRSK2), specific for the SR family of splicing factors in mouse and human chromosomes | Q28141202 | ||
| Signaling to chromatin through histone modifications | Q28142598 | ||
| Protein kinase CK2 phosphorylates and activates the SR protein-specific kinase 1 | Q28207031 | ||
| Temporal association of protamine 1 with the inner nuclear membrane protein lamin B receptor during spermiogenesis | Q28236819 | ||
| SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors | Q28289413 | ||
| Histones H3/H4 form a tight complex with the inner nuclear membrane protein LBR and heterochromatin protein 1 | Q28360319 | ||
| Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis | Q28511396 | ||
| Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma | Q40296329 | ||
| The SR protein family: pleiotropic functions in pre-mRNA splicing | Q41083714 | ||
| Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1. | Q41560943 | ||
| Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones | Q41836294 | ||
| Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis | Q42412081 | ||
| Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeast | Q42529068 | ||
| Fission yeast mitotic regulator Dsk1 is an SR protein-specific kinase | Q42673467 | ||
| Interactions between two fission yeast serine/arginine-rich proteins and their modulation by phosphorylation | Q43002427 | ||
| Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation | Q43147112 | ||
| Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle | Q43474246 | ||
| Immunoelectron microscopical distribution of histones H2B and H3 and protamines in the course of mouse spermiogenesis | Q44306037 | ||
| Regulation of binding of lamin B receptor to chromatin by SR protein kinase and cdc2 kinase in Xenopus egg extracts | Q44725333 | ||
| Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome | Q46634476 | ||
| Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2. | Q46670815 | ||
| RNA association or phosphorylation of the RS domain prevents aggregation of RS domain-containing proteins | Q46893975 | ||
| SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development | Q47068882 | ||
| Perinuclear localization of chromatin facilitates transcriptional silencing | Q47675987 | ||
| Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles | Q28586232 | ||
| Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein | Q28586667 | ||
| Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2 | Q28589432 | ||
| CRM1 is responsible for intracellular transport mediated by the nuclear export signal | Q29547861 | ||
| Metabolic control through the PGC-1 family of transcription coactivators | Q29616509 | ||
| Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction | Q29619822 | ||
| Phosphorylation by LAMMER protein kinases: determination of a consensus site, identification of in vitro substrates, and implications for substrate preferences | Q30807404 | ||
| Serological identification of adult T-cell leukaemia-associated antigens. | Q33220307 | ||
| Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila | Q33511955 | ||
| Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation | Q33705060 | ||
| Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4. | Q33912824 | ||
| A computational analysis of sequence features involved in recognition of short introns | Q33944374 | ||
| Regulated cellular partitioning of SR protein-specific kinases in mammalian cells | Q34325765 | ||
| Suppression of hepatitis B virus replication by SRPK1 and SRPK2 via a pathway independent of the phosphorylation of the viral core protein | Q34445705 | ||
| Unique chromatin remodeling and transcriptional regulation in spermatogenesis | Q34699908 | ||
| The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1. | Q34774397 | ||
| Utilization of host SR protein kinases and RNA-splicing machinery during viral replication | Q34983999 | ||
| p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1. | Q35150453 | ||
| Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing | Q35206040 | ||
| Phosphorylation by SR kinases regulates the binding of PTB-associated splicing factor (PSF) to the pre-mRNA polypyrimidine tract | Q35741673 | ||
| The A-type cyclins and the meiotic cell cycle in mammalian male germ cells | Q35843959 | ||
| Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors | Q35880597 | ||
| A proposed signaling motif for nuclear import in mRNA processing via the formation of arginine claw | Q35975495 | ||
| Concepts in nuclear architecture | Q36098945 | ||
| Phosphorylation regulates in vivo interaction and molecular targeting of serine/arginine-rich pre-mRNA splicing factors | Q36342149 | ||
| Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways | Q36510743 | ||
| Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus | Q36748159 | ||
| The splicing factor SC35 has an active role in transcriptional elongation | Q36952048 | ||
| Nuclear cyclin D1: an oncogenic driver in human cancer | Q37470373 | ||
| Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor | Q37622680 | ||
| Vertebrate protamine genes and the histone-to-protamine replacement reaction | Q37716790 | ||
| Functional coexpression of serine protein kinase SRPK1 and its substrate ASF/SF2 in Escherichia coli | Q39542648 | ||
| Clking on PGC-1alpha to inhibit gluconeogenesis | Q39581322 | ||
| ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation | Q39744901 | ||
| Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator. | Q40122836 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | regulation of mRNA splicing, via spliceosome | Q21109627 |
| SRSF protein kinase 1 | Q21154841 | ||
| SRSF protein kinase 2 | Q21201377 | ||
| P304 | page(s) | 570-86 | |
| P577 | publication date | 2011-02-01 | |
| P1433 | published in | FEBS Journal | Q1388041 |
| P1476 | title | Serine-arginine protein kinases: a small protein kinase family with a large cellular presence | |
| P478 | volume | 278 |
| Q35059508 | A preliminary investigation on placenta protein profile reveals only modest changes in well controlled gestational diabetes mellitus |
| Q39497293 | AEE788 Inhibits Basal Body Assembly and Blocks DNA Replication in the African Trypanosome |
| Q24304362 | ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility |
| Q36108838 | Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma |
| Q34551462 | An RS motif within the Epstein-Barr virus BLRF2 tegument protein is phosphorylated by SRPK2 and is important for viral replication |
| Q37271140 | Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function |
| Q46812862 | Characterization of protein kinase PsSRPKL, a novel pathogenicity factor in the wheat stripe rust fungus |
| Q90481284 | Clinical and functional significance of CHK1-S, an alternatively spliced isoform of the CHK1 gene, in hepatocellular carcinoma |
| Q36280437 | Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus. |
| Q28073341 | Control of human papillomavirus gene expression by alternative splicing |
| Q92394263 | Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer |
| Q58104270 | Delta-secretase (AEP) mediates tau-splicing imbalance and accelerates cognitive decline in tauopathies |
| Q46348230 | Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation. |
| Q36271734 | Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization |
| Q53221473 | Expression of SRPK1 in gliomas and its role in glioma cell lines viability. |
| Q34625580 | Functional analysis of the Aspergillus nidulans kinome |
| Q51142701 | High-throughput sperm differential proteomics suggests that epigenetic alterations contribute to failed assisted reproduction. |
| Q37252986 | Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA Processing |
| Q34593811 | Human papillomavirus type 1 E1^E4 protein is a potent inhibitor of the serine-arginine (SR) protein kinase SRPK1 and inhibits phosphorylation of host SR proteins and of the viral transcription and replication regulator E2 |
| Q90390227 | Human papillomavirus type 16 infection activates the host serine arginine protein kinase 1 (SRPK1) - splicing factor axis |
| Q90310919 | Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation |
| Q53163730 | Interacting factors and cellular localization of SR protein-specific kinase Dsk1. |
| Q34326195 | Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. |
| Q38744125 | Knockdown of Serine-Arginine Protein Kinase 1 Inhibits the Growth and Migration in Renal Cell Carcinoma Cells |
| Q41664396 | Lamin B Receptor: Interplay between Structure, Function and Localization. |
| Q89819845 | Loss of miR-369 Promotes Tau Phosphorylation by Targeting the Fyn and Serine/Threonine-Protein Kinase 2 Signaling Pathways in Alzheimer's Disease Mice |
| Q39396142 | MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle |
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| Q28547020 | Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340) |
| Q41953953 | Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia. |
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