Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization

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Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2017PLoSO..1271328K
P356DOI10.1371/JOURNAL.PONE.0171328
P932PMC publication ID5293202
P698PubMed publication ID28166275

P2093author name stringEleni Nikolakaki
Thomas Giannakouros
Maria Koutroumani
Metaxia Vlassi
Georgios E Papadopoulos
P2860cites workRole of evolutionary information in predicting the disulfide-bonding state of cysteine in proteins.Q52209259
The genetics of disulfide bond metabolismQ77936221
Cloning and characterization of an alternatively spliced form of SR protein kinase 1 that interacts specifically with scaffold attachment factor-BQ24291570
Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatinQ24316205
Serine-arginine protein kinases: a small protein kinase family with a large cellular presenceQ24323291
The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2Q24324040
A helix propensity scale based on experimental studies of peptides and proteinsQ24537262
Phosphorylation mechanism and structure of serine-arginine protein kinasesQ24612980
Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasmQ24644906
DISULFIND: a disulfide bonding state and cysteine connectivity prediction serverQ24680281
The structure of Sky1p reveals a novel mechanism for constitutive activityQ27629551
SR protein kinase 1 is resilient to inactivationQ27643535
Scalable molecular dynamics with NAMDQ27860718
Conservation in budding yeast of a kinase specific for SR splicing factorsQ27935651
SRPK1 and LBR protein kinases show identical substrate specificitiesQ28137892
Protein kinase CK2 phosphorylates and activates the SR protein-specific kinase 1Q28207031
SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factorsQ28289413
SRPK1 and Akt Protein Kinases Phosphorylate the RS Domain of Lamin B Receptor with Distinct Specificity: A Combined Biochemical and In Silico ApproachQ28551544
Regulation of vertebrate nervous system alternative splicing and development by an SR-related proteinQ28586667
Surface comparison of active and inactive protein kinases identifies a conserved activation mechanismQ29616720
Prediction of reversibly oxidized protein cysteine thiols using protein structure propertiesQ30367869
Protein disulfide bond formation in the cytoplasm during oxidative stressQ33199830
Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.Q33605329
Disulfide bond formation in the Escherichia coli cytoplasm: an in vivo role reversal for the thioredoxinsQ33889552
Disulphide bridges in globular proteinsQ34284906
Regulated cellular partitioning of SR protein-specific kinases in mammalian cellsQ34325765
DiANNA 1.1: an extension of the DiANNA web server for ternary cysteine classificationQ34547962
Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1Q35064474
Disulfide bonds as switches for protein functionQ35114294
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleusQ36161960
Nucleotide release sequences in the protein kinase SRPK1 accelerate substrate phosphorylationQ37031421
Thiol-based redox switches in eukaryotic proteinsQ37322426
Post-translational control of protein function by disulfide bond cleavage.Q38063913
Regulation of splicing by SR proteins and SR protein-specific kinasesQ38092678
The ratio of SRPK1/SRPK1a regulates erythroid differentiation in K562 leukaemic cells.Q38341685
Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exonsQ40395747
Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperonesQ41836294
Phosphorylation of the arginine/serine repeats of lamin B receptor by SRPK1-insights from molecular dynamics simulationsQ43576416
Large-scale prediction of disulphide bridges using kernel methods, two-dimensional recursive neural networks, and weighted graph matchingQ46244966
Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.Q46670815
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)e0171328
P577publication date2017-02-06
P1433published inPLOS OneQ564954
P1476titleEvidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization
P478volume12

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cites work (P2860)
Q90496900A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast
Q54122877MiR-126 functions as a tumor suppressor by targeting SRPK1 in human gastric cancer.
Q90394579Serine arginine protein kinase 1 (SRPK1): a moonlighting protein with theranostic ability in cancer prevention
Q42700823The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer

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