Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

scientific article

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1101/GAD.2000111
P3181OpenCitations bibliographic resource ID667576
P932PMC publication ID3012936
P698PubMed publication ID21205866
P5875ResearchGate publication ID49728459

P2093author name stringQing Lu
Li Li
Bin Zhao
Chen-Ying Liu
Kun-Liang Guan
Lloyd H Wang
Qunying Lei
P2860cites workAngiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formationQ24290939
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Q24293710
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth controlQ24299106
Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylationQ24300596
Tumor suppressor LATS1 is a negative regulator of oncogene YAPQ24304725
TEAD mediates YAP-dependent gene induction and growth controlQ24336045
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approachQ24633776
Nore1 and RASSF1 regulation of cell proliferation and of the MST1/2 kinases.Q52015849
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.Q52100108
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.Q52704046
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathwayQ81088455
The human tumour suppressor LATS1 is activated by human MOB1 at the membraneQ83287887
Expression of Yes-associated protein in common solid tumorsQ24657592
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 ampliconQ24682018
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1Q28116287
Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domainsQ28212001
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell linesQ28219379
A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cellsQ28238594
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAPQ28266862
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionQ28281214
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)Q28287783
Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated proteinQ28306685
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferationQ28507494
Angiomotin regulates visceral endoderm movements during mouse embryogenesisQ28587014
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppressionQ28591557
YAP1 increases organ size and expands undifferentiated progenitor cellsQ28592519
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein ExpandedQ28752559
Elucidation of a universal size-control mechanism in Drosophila and mammalsQ29618935
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosisQ29619851
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and wartsQ29620457
Yes-associated protein is an independent prognostic marker in hepatocellular carcinomaQ33611696
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathwayQ33644875
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to ExpandedQ33934781
Control of cell proliferation and apoptosis by mob as tumor suppressor, matsQ34402685
p130-angiomotin associates to actin and controls endothelial cell shapeQ34517933
The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in DrosophilaQ34559232
The bantam microRNA is a target of the hippo tumor-suppressor pathwayQ34562924
Differential roles of p80- and p130-angiomotin in the switch between migration and stabilization of endothelial cellsQ34731285
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosisQ36336754
Multiple microalterations detected at high frequency in oral cancerQ38441119
Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell linesQ39827808
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator YorkieQ39872336
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cellsQ39991840
Characterization of the interface between normal and transformed epithelial cellsQ42450915
Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.Q42625092
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathwayQ44591663
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma.Q46433336
Shar-pei mediates cell proliferation arrest during imaginal disc growth in DrosophilaQ47072038
Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in DrosophilaQ47072497
Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics.Q48364922
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAngiomotinQ4763281
hippo signalingQ5768379
Angiomotin-like 1Q21981186
P304page(s)51-63
P577publication date2011-01-01
P1433published inGenes & DevelopmentQ1524533
P1476titleAngiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
P478volume25