The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

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The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex is …
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scholarly articleQ13442814

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P819ADS bibcode1996PNAS...9313973S
P356DOI10.1073/PNAS.93.24.13973
P3181OpenCitations bibliographic resource ID3575558
P932PMC publication ID19479
P698PubMed publication ID8943045
P5875ResearchGate publication ID14264321

P2093author name stringM Takeuchi
D V Goeddel
H B Shu
P2860cites workMolecular cloning and expression of a receptor for human tumor necrosis factorQ24303604
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genesQ24315805
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathwaysQ24317441
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorQ24318280
The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activationQ24318742
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complexQ24329065
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activationQ27732032
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteinsQ28117866
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infectionQ28509078
Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factorQ28512161
Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenesQ28593744
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient miceQ28593915
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40Q28610812
Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa BQ29618096
The Fas death factorQ29620461
The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and deathQ29620519
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specificQ33336314
Molecular cloning and expression of the human 55 kd tumor necrosis factor receptorQ33903826
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteinsQ33909940
Two TNF receptorsQ35231014
Tumor necrosis factor. Characterization at the molecular, cellular and in vivo levelQ36404676
Aggregation of the intracellular domain of the type 1 tumor necrosis factor receptor defined by the two-hybrid systemQ36739112
The two different receptors for tumor necrosis factor mediate distinct cellular responsesQ37609601
Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activityQ37896220
Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascadesQ38326175
Tumor necrosis, cachexia, shock, and inflammation: a common mediatorQ39532135
A novel domain within the 55 kd TNF receptor signals cell deathQ41528172
A novel protein domain required for apoptosis. Mutational analysis of human Fas antigenQ41553101
Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequencesQ41729888
Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptorQ41747117
Negative selection of thymocytes. A novel polymerase chain reaction-based molecular analysis detects requirements for macromolecular synthesisQ44243483
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell deathQ46725238
Self-association of the Death Domains of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 EffectsQ59707705
Both tumor necrosis factor receptor types mediate proliferative signals in human mononuclear cell activationQ67854330
Tumor necrosis factors: gene structure and biological activitiesQ68759964
Tumor necrosis factor receptor p75 mediates cell-specific activation of nuclear factor kappa B and induction of human cytomegalovirus enhancerQ72287816
P433issue24
P407language of work or nameEnglishQ1860
P304page(s)13973-8
P577publication date1996-11-26
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
P478volume93

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cites work (P2860)
Q58862452A birthday gift for TRADD
Q22254604A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction
Q36071998A novel role for RIP1 kinase in mediating TNFα production
Q28202445A novel zinc finger protein interacts with receptor-interacting protein (RIP) and inhibits tumor necrosis factor (TNF)- and IL1-induced NF-kappa B activation
Q28187818A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha
Q98154728A simple and highly efficient method for multi-allelic CRISPR-Cas9 editing in primary cell cultures
Q28285612ASK1 is essential for JNK/SAPK activation by TRAF2
Q48615547Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
Q28139462Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP
Q35083907Acute tumor necrosis factor-alpha-induced liver injury in the absence of tumor necrosis factor receptor-associated factor 1 gene expression
Q41835791Assembly and regulation of the CD40 receptor complex in human B cells
Q35925874Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily
Q36485042Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis
Q35555309Autoantibody formation in patients with rheumatoid arthritis treated with anti-TNF alpha
Q24609324Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis
Q41516352BIRC3 is a biomarker of mesenchymal habitat of glioblastoma, and a mediator of survival adaptation in hypoxia-driven glioblastoma habitats.
Q36591473BIRC3 is a novel driver of therapeutic resistance in Glioblastoma
Q39224370Baculoviral inhibitors of apoptosis repeat containing (BIRC) proteins fine-tune TNF-induced nuclear factor κB and c-Jun N-terminal kinase signalling in mouse pancreatic beta cells.
Q35886664Baculovirus inhibitor of apoptosis functions at or upstream of the apoptotic suppressor P35 to prevent programmed cell death
Q46203326Birc2 (cIap1) regulates endothelial cell integrity and blood vessel homeostasis.
Q36954601Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation
Q24315042Casper is a FADD- and caspase-related inducer of apoptosis
Q34082790Cell death control in lymphocytes.
Q41554119Cell death induction by receptors of the TNF family: towards a molecular understanding.
Q34540067Characterization of Potent SMAC Mimetics that Sensitize Cancer Cells to TNF Family-Induced Apoptosis
Q38530635Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1.
Q24317322Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1
Q32053895Construction of a modular yeast two-hybrid cDNA library from human EST clones for the human genome protein linkage map.
Q34234140Cytokine signaling and Epstein-Barr virus-mediated cell transformation
Q26779054DDX3, a potential target for cancer treatment
Q39940614Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4.
Q33690256Death signal transduction induced by co-immobilized TNF-α plus IFN-γ and the development of polymeric anti-cancer drugs
Q47933765Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict
Q43543078Decreased fumonisin hepatotoxicity in mice with a targeted deletion of tumor necrosis factor receptor 1.
Q42389083Differential Regulation of Bcl-xL Gene Expression by Corticosterone, Progesterone, and Retinoic Acid
Q24294565Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases
Q40375014Distinct role of calmodulin and calmodulin-dependent protein kinase-II in lipopolysaccharide and tumor necrosis factor-alpha-mediated suppression of apoptosis and antiapoptotic c-IAP2 gene expression in human monocytic cells
Q29618716Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
Q41020511Effect of gene transfer of tumor necrosis factor receptors into human lung carcinoma cell line
Q40956523Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice
Q28207830Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis
Q37343955Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2.
Q47716037Epidermal signal transduction and transcription factor activation in activated keratinocytes.
Q24516975Epstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2
Q47699242Expression of FK506-binding protein 51 (FKBP51) in Mycosis fungoides
Q46606781Expressions of tumor necrosis factor-α, its receptor I, II and receptor-associated factor 2 in the porcine corpus luteum during the estrous cycle and early pregnancy
Q28187584FLASH coordinates NF-kappa B activity via TRAF2
Q44422902Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis
Q38691490Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death
Q28567626Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death
Q41707879Free radicals, calcium, and the synaptic plasticity-cell death continuum: emerging roles of the transcription factor NF kappa B.
Q28137773From receptors to stress-activated MAP kinases
Q36453363Gene expression profiling in human autoimmunity.
Q28207670Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1
Q22003914Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth
Q24323286Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1
Q24533921Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c
Q24300707IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
Q24300734IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
Q37302745IAP-targeted therapies for cancer
Q39138078IAPs and Cell Death
Q37148694IAPs: what's in a name?
Q28245341Identification and characterization of an IkappaB kinase
Q28200039Identification of XAF1 as an antagonist of XIAP anti-Caspase activity
Q40591236Identification of a ZU5 and death domain-containing inhibitor of NF-kappaB.
Q28199348Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2
Q34268863Identification of a nuclear protein that promotes NF-κB activation
Q24321594Identification of an antiapoptotic protein complex at death receptors
Q40258580Inducible GBP5 Mediates the Antiviral Response via Interferon-Related Pathways during Influenza A Virus Infection.
Q40251263Inducible Rubicon facilitates viral replication by antagonizing interferon production
Q33632016Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.
Q38310679Inflammatory versus proliferative processes in epidermis. Tumor necrosis factor alpha induces K6b keratin synthesis through a transcriptional complex containing NFkappa B and C/EBPbeta
Q36583948Inhibition of reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs).
Q33773613Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM.
Q34223547Inositol 1,3,4-trisphosphate 5/6-kinase inhibits tumor necrosis factor-induced apoptosis
Q40858627Interaction of Drosophila inhibitors of apoptosis with thick veins, a type I serine/threonine kinase receptor for decapentaplegic
Q24291474Interchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signaling
Q36597952Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.
Q23912832Involvement of 5'-flanking kB-like sites within bcl-x gene in silica-induced bcl-x expression
Q45743372Involvement of two NF-kappa B binding elements in tumor necrosis factor alpha -, CD40-, and epstein-barr virus latent membrane protein 1-mediated induction of the cellular inhibitor of apoptosis protein 2 gene
Q24570128Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
Q34270866Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC.
Q40752073Lack of requirement of STAT1 for activation of nuclear factor-kappaB, c-Jun NH2-terminal protein kinase, and apoptosis by tumor necrosis factor-alpha
Q37459028Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death
Q30432425Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans
Q57816326MicroRNA-647 promotes the therapeutic effectiveness of argon-helium cryoablation and inhibits cell proliferation through targeting TRAF2 via the NF-κB signaling pathway in non-small cell lung cancer
Q99616984Modulating TRADD to restore cellular homeostasis and inhibit apoptosis
Q29619302NF-kappaB at the crossroads of life and death
Q40568401NF-kappaB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion
Q34127458Natural products as targeted modulators of the nuclear factor-kappaB pathway
Q38559586Necroptosis: A new way of dying?
Q37801950New developments on the TNFα-mediated signalling pathways
Q38166953New paradigms in inflammatory signaling in vascular endothelial cells
Q36325686Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms
Q36851742Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.
Q40533310Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.
Q50526571Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions.
Q34619889Peripheral noxious stimulation reduces withdrawal threshold to mechanical stimuli after spinal cord injury: role of tumor necrosis factor alpha and apoptosis
Q34139073Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosis
Q34007024Proinflammatory and proapoptotic activities associated with Bordetella pertussis filamentous hemagglutinin
Q24303616RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation
Q55454646RIG-I-Like Receptors as Novel Targets for Pan-Antivirals and Vaccine Adjuvants Against Emerging and Re-Emerging Viral Infections.
Q39600014Radiosensitization of head and neck squamous cell carcinoma by a SMAC-mimetic compound, SM-164, requires activation of caspases.
Q34616595Recent advances in understanding NF-kappaB regulation
Q40555067Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro
Q34274842Receptor-mediated choreography of life and death.
Q28141339Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation
Q22001513Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
Q35480734Regulating TRAIL receptor-induced cell death at the membrane : a deadly discussion
Q37009989Regulation of Apoptosis by Gram-Positive Bacteria: Mechanistic Diversity and Consequences for Immunity
Q35920998Regulation of NF-κB by the CARD proteins
Q38152946Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death
Q37628447Regulation of death receptor signaling by the ubiquitin system
Q56891449Regulation of innate and adaptive antitumor immunity by IAP antagonists
Q92923628Ripoptocide - A Spark for Inflammation
Q33784729Role of the TRAF binding site and NF-kappaB activation in Epstein-Barr virus latent membrane protein 1-induced cell gene expression
Q38189358Role of the TWEAK-Fn14-cIAP1-NF-κB Signaling Axis in the Regulation of Myogenesis and Muscle Homeostasis
Q28203033SINK Is a p65-interacting Negative Regulator of NF-κB-dependent Transcription
Q39375981Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells
Q24630120Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor
Q30662715Screening from a subtracted embryonic chick hindbrain cDNA library: identification of genes expressed during hindbrain, midbrain and cranial neural crest development
Q44872226Selective regulation by delta-PKC and PI 3-kinase in the assembly of the antiapoptotic TNFR-1 signaling complex in neutrophils
Q41724478Signal transduction through NF-kappa B.
Q33693806Signaling to NF-kappaB: regulation by ubiquitination
Q44762625Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells
Q40621223Soluble IL-6 Receptor and IL-27 Subunit p28 Protein Complex Mediate the Antiviral Response through the Type III IFN Pathway
Q24539054Stress-induced decrease in TRAF2 stability is mediated by Siah2
Q48906591Structural biology of tumor necrosis factor demonstrated for undergraduates instruction by computer simulation.
Q36580820Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control
Q24292181T2BP, a novel TRAF2 binding protein, can activate NF-kappaB and AP-1 without TNF stimulation
Q22254711T6BP, a TRAF6-interacting protein involved in IL-1 signaling
Q54439940TACI induces cIAP1-mediated ubiquitination of NIK by TRAF2 and TANK to limit non-canonical NF-kappaB signaling.
Q37948115TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer
Q30578474TNF receptor associated factors in cytokine signaling.
Q30453341TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3
Q21093232TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
Q24292505TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
Q28203709TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
Q39832953TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling
Q63976848TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy
Q83300040TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells
Q48366195TRADD, TRAF2, RIP1 and TAK1 are required for TNF-α-induced pro-labour mediators in human primary myometrial cells.
Q36361121TRAF1 gene polymorphism correlates with the titre of Gp210 antibody in patients with primary biliary cirrhosis
Q43168654TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis
Q43170389TRAF2 is a biologically important necroptosis suppressor
Q36624553TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1
Q39857832TRAF2 suppresses basal IKK activity in resting cells and TNFalpha can activate IKK in TRAF2 and TRAF5 double knockout cells
Q24314392TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis
Q28584897Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation
Q28115962Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma
Q90395021Targeting XIAP for Promoting Cancer Cell Death-The Story of ARTS and SMAC
Q37855868Targeting inhibitor of apoptosis proteins for therapeutic intervention.
Q45951863The CXXC finger 5 protein is required for DNA damage-induced p53 activation.
Q39125509The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection
Q24646694The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaB
Q24554457The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation
Q42148237The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB.
Q28190485The TNF receptor 1: a split personality complex
Q28198125The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators
Q24532851The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
Q35964780The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation
Q73745042The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
Q37989135The emerging role of linear ubiquitination in cell signaling
Q46200610The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.
Q35591690The inhibitors of apoptosis: there is more to life than Bcl2.
Q22009927The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation
Q52952279The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2.
Q35902423The protein structures that shape caspase activity, specificity, activation and inhibition
Q39596927The residues between the two transformation effector sites of Epstein-Barr virus latent membrane protein 1 are not critical for B-lymphocyte growth transformation
Q34102964The role of NF-kappaB/IkappaB proteins in cancer: implications for novel treatment strategies
Q28293167The role of c-FLIP in modulation of CD95-induced apoptosis
Q27619945The structural basis for the recognition of diverse receptor sequences by TRAF2
Q28140478The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis
Q59707693The yeast two-hybrid screening technique and its use in the study of protein-protein interactions in apoptosis
Q35192167Thermodynamic characterization of the interaction between TRAF2 and tumor necrosis factor receptor peptides by isothermal titration calorimetry
Q23913393Time-dependent apoptosis of alveolar macrophages from rats exposed to bleomycin: involvement of TNF receptor 2
Q73649342Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor
Q58793110Tumor Necrosis Factor Receptor-Associated Factor Regulation of Nuclear Factor κB and Mitogen-Activated Protein Kinase Pathways
Q33864445Tumor necrosis factor (TNF)-alpha and TNF receptors in viral pathogenesis
Q28575022Tumor necrosis factor receptor 1 and its signaling intermediates are recruited to lipid rafts in the traumatized brain
Q40626565Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation
Q34135071Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling.
Q34185821Tumor necrosis factor signaling.
Q35791667Tumor necrosis factor-alpha acts as a complete mitogen for primary rat hepatocytes
Q42825963Tumor necrosis factor-alpha mediated activation of signal transduction cascades and transcription factors in 3T3-L1 adipocytes
Q34071248Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB.
Q35739622UVB-induced association of tumor necrosis factor (TNF) receptor 1/TNF receptor-associated factor-2 mediates activation of Rel proteins
Q26998711Ubiquitin in the immune system
Q33744532Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response
Q48453757When Pain Hurts: Nociceptive Stimulation Induces a State of Maladaptive Plasticity and Impairs Recovery after Spinal Cord Injury.
Q24533501XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
Q40227188ZNT7 binds to CD40 and influences CD154-triggered p38 MAPK activity in B lymphocytes-a possible regulatory mechanism for zinc in immune function
Q27345421cIAP-1 controls innate immunity to C. pneumoniae pulmonary infection
Q36574102ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein
Q36674736γ-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling.

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