scholarly article | Q13442814 |
P356 | DOI | 10.1016/0092-8674(94)90361-1 |
P698 | PubMed publication ID | 8124722 |
P50 | author | Joseph L. Goldstein | Q271424 |
P2093 | author name string | M S Brown | |
R G Anderson | |||
R K Pathak | |||
C K Garcia | |||
P2860 | cites work | Protein measurement with the Folin phenol reagent | Q20900776 |
Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase | Q28131695 | ||
Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by alpha-cyano-4-hydroxycinnamate | Q28622734 | ||
The 12-transmembrane helix transporters | Q34728878 | ||
Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice | Q36223333 | ||
Regulation of lactate metabolism in vivo. | Q38631655 | ||
L-lactate transport in Ehrlich ascites-tumour cells | Q39101991 | ||
The mechanism of lactate transport in human erythrocytes | Q39228813 | ||
Transport of lactate and other monocarboxylates across mammalian plasma membranes | Q40897800 | ||
Reconstitution of the L-lactate carrier from rat and rabbit erythrocyte plasma membranes | Q42046166 | ||
Identification and partial purification of the erythrocyte L-lactate transporter | Q42114050 | ||
Substrate and inhibitor specificity of monocarboxylate transport into heart cells and erythrocytes. Further evidence for the existence of two distinct carriers | Q42794898 | ||
Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate | Q42849386 | ||
Lactate transport is mediated by a membrane-bound carrier in rat skeletal muscle sarcolemmal vesicles | Q46832886 | ||
Preferential uptake of lactate by the normal myocardium in dogs. | Q51877687 | ||
Lactate transport by skeletal muscle sarcolemmal vesicles. | Q52395931 | ||
A comparative microphotometric study of succinate dehydrogenase activity levels in type I, IIA and IIB fibres of mammalian and human muscles. | Q53940113 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 865-73 | |
P577 | publication date | 1994-03-11 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle | |
P478 | volume | 76 |
Q50253921 | 3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects |
Q31150018 | A 44-kDa of protein identical to the N-terminal amino acid sequence of MCT1 in human circulation |
Q47228407 | A look at the smelly side of physiology: transport of short chain fatty acids. |
Q28343896 | A pyruvate-proton symport and an H+-ATPase regulate the intracellular pH of Trypanosoma brucei at different stages of its life cycle |
Q28580635 | AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10 |
Q41860134 | Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner |
Q34432747 | Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles |
Q90410262 | Altered expression of lactate dehydrogenase and monocarboxylate transporter involved in lactate metabolism in broiler wooden breast |
Q36411671 | An Na(+)-independent short-chain fatty acid transporter contributes to intracellular pH regulation in murine colonocytes |
Q73040080 | Anion antiport mechanism is involved in transport of lactic acid across intestinal epithelial brush-border membrane |
Q42067164 | Assays for inhibitors of CAAX farnesyltransferase in vitro and in intact cells |
Q44781465 | Astrocytes and synaptosomes transport and metabolize lactate and acetate differently |
Q36657652 | Autoimmune modulation of astrocyte-mediated homeostasis. |
Q28119091 | Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70) |
Q43548502 | Blockade of lactate transport exacerbates delayed neuronal damage in a rat model of cerebral ischemia |
Q28263445 | Blood lactate measurements and analysis during exercise: a guide for clinicians |
Q33904234 | Blood-brain barrier permeability to small and large molecules |
Q34170853 | Brain-derived neurotrophic factor enhances the expression of the monocarboxylate transporter 2 through translational activation in mouse cultured cortical neurons. |
Q24630430 | CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression |
Q50034271 | Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness. |
Q41140046 | Carrier-mediated intestinal transport of drugs |
Q71788652 | Carrier-mediated lactate entry into isolated hepatocytes from fed and starved rats: Zonal distribution and temperature dependence |
Q73213766 | Carrier-mediated transport of monocarboxylic acids in primary cultured epithelial cells from rabbit oral mucosa |
Q37608831 | Cell-cell and intracellular lactate shuttles. |
Q61774068 | Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy |
Q57612087 | Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat |
Q46219945 | Cellular expression of a monocarboxylate transporter (MCT1) in the mammary gland and sebaceous gland of mice |
Q46408617 | Cellular expression of a sodium-dependent monocarboxylate transporter (Slc5a8) and the MCT family in the mouse kidney |
Q42484582 | Cellular expression of monocarboxylate transporters in the female reproductive organ of mice: implications for the genital lactate shuttle |
Q27023017 | Cerebral metabolism following traumatic brain injury: new discoveries with implications for treatment |
Q44628049 | Characterization of butyrate transport across the luminal membranes of equine large intestine. |
Q39218343 | Characterization of the carrier-mediated transport of ketoprofen, a nonsteroidal anti-inflammatory drug, in rabbit corneal epithelium cells |
Q42994129 | Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes |
Q41978202 | Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. |
Q51928812 | Characterization of the uptake mechanism for a novel loop diuretic, M17055, in Caco-2 cells: involvement of organic anion transporting polypeptide (OATP)-B. |
Q27023363 | Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization |
Q46138165 | Choice of DMEM, formulated with or without pyruvate, plays an important role in assessing the in vitro cytotoxicity of oxidants and prooxidant nutraceuticals |
Q71265090 | Chronic muscle stimulation increases lactate transport in rat skeletal muscle |
Q37706691 | Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation. |
Q24318829 | Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past |
Q22010562 | Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2 |
Q28579132 | Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation |
Q48949053 | Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons |
Q94948205 | Cooperative transport mechanism of human monocarboxylate transporter 2 |
Q28570856 | D-Lactate transport and metabolism in rat liver mitochondria |
Q43641724 | Decreased monocarboxylate transporter 1 in rat soleus and EDL muscles exposed to clenbuterol |
Q41757942 | Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush. |
Q37634927 | Design and applications of biodegradable polyester tissue scaffolds based on endogenous monomers found in human metabolism |
Q42442071 | Developmental and hormonal regulation of the monocarboxylate transporter 2 (MCT2) expression in the mouse germ cells |
Q44361284 | Direct and indirect lactate oxidation in trained and untrained men. |
Q38130850 | Disrupting proton dynamics and energy metabolism for cancer therapy |
Q42474219 | Distribution of monocarboxylate transporters MCT1 and MCT2 in rat retina |
Q48588696 | Distribution of monocarboxylate transporters MCT1-MCT8 in rat tissues and human skeletal muscle |
Q41860789 | Effect of Lactate Accumulation during Exercise-induced Muscle Fatigue on the Sensorimotor Cortex |
Q45384723 | Effects of a co-treatment with pyruvate and creatine on dendritic spines in rat hippocampus and posterodorsal medial amygdala in a phenylketonuria animal model |
Q35932745 | Endogenous Nutritive Support after Traumatic Brain Injury: Peripheral Lactate Production for Glucose Supply via Gluconeogenesis |
Q34623667 | Energy metabolism in the normal and failing heart: potential for therapeutic interventions |
Q46496977 | Expression and membrane localization of MCT isoforms along the length of the human intestine |
Q44888085 | Expression of MHC-beta and MCT1 in cardiac muscle after exercise training in myocardial-infarcted rats |
Q48666726 | Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats |
Q36015325 | Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain |
Q44437610 | Expression of monocarboxylic acid transporters (MCT) in brain cells. Implication for branched chain alpha-ketoacids transport in neurons. |
Q52542413 | Extracellular Acid-Base Balance and Ion Transport Between Body Fluid Compartments. |
Q34431872 | Extracellular pH regulation in microdomains of colonic crypts: effects of short-chain fatty acids |
Q41684485 | First-pass effect: significance of the intestine for absorption and metabolism |
Q38255944 | From microbe to man: the role of microbial short chain fatty acid metabolites in host cell biology |
Q28373047 | Functional clarification of MCT1-mediated transport of monocarboxylic acids at the blood-brain barrier using in vitro cultured cells and in vivo BUI studies |
Q74110740 | Functional evidence for a monocarboxylate transporter (MCT) in strial marginal cells and molecular evidence for MCT1 and MCT2 in stria vascularis |
Q37102632 | Gem-1 encodes an SLC16 monocarboxylate transporter-related protein that functions in parallel to the gon-2 TRPM channel during gonad development in Caenorhabditis elegans |
Q90468260 | Glia-neuron energy metabolism in health and diseases: New insights into the role of nervous system metabolic transporters |
Q38844334 | Global Analysis of Protein Expression and Phosphorylation Levels in Nicotine-Treated Pancreatic Stellate Cells |
Q33578118 | H+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine |
Q45750314 | High expression of monocarboxylate transporter 4 predicts poor prognosis in patients with lung adenocarcinoma |
Q50218128 | High-intensity intermittent exercise training with chlorella intake accelerates exercise performance and muscle glycolytic and oxidative capacity in rats |
Q37824123 | Hijacking solute carriers for proton-coupled drug transport. |
Q22003999 | Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter |
Q28081811 | Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symporters |
Q24653763 | Identification and characterization of a monocarboxylate transporter (MCT1) in pig and human colon: its potential to transport L-lactate as well as butyrate |
Q24302046 | Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication |
Q34583113 | Immunogold cytochemistry identifies specialized membrane domains for monocarboxylate transport in the central nervous system |
Q33216391 | Immunohistochemical analysis of MCT1, MCT2 and MCT4 expression in rat plantaris muscle. |
Q28377150 | Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1 |
Q43794399 | Impaired sarcolemmal vesicle lactate uptake and skeletal muscle MCT1 and MCT4 expression in obese Zucker rats |
Q26995687 | Importance of pH homeostasis in metabolic health and diseases: crucial role of membrane proton transport |
Q44620965 | Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol |
Q45076784 | Interaction with antigen-specific T cells regulates expression of the lactate transporter MCT1 in primary rat astrocytes: specific link between immunity and homeostasis |
Q91639792 | Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability |
Q40882210 | Intracellular pH regulation in a nonmalignant and a derived malignant human breast cell line |
Q33618507 | Intratumoral lactate metabolism in Barrett's esophagus and adenocarcinoma |
Q64940613 | Ion Transporters, Channelopathies, and Glucose Disorders. |
Q28083173 | Is L-lactate a novel signaling molecule in the brain? |
Q41598109 | Isoprenoid metabolism in the vertebrate retina |
Q49305748 | L(+)-lactate binding to a protein in rat skeletal muscle plasma membranes |
Q47594603 | Lactate Metabolism in Human Lung Tumors |
Q89955789 | Lactate as a fulcrum of metabolism |
Q35125579 | Lactate as a pivotal element in neuron-glia metabolic cooperation. |
Q50532023 | Lactate in the brain: from metabolic end-product to signalling molecule. |
Q46122111 | Lactate kinetics at the lactate threshold in trained and untrained men. |
Q36973402 | Lactate metabolism in anoxic turtles: an integrative review |
Q24677962 | Lactate metabolism: a new paradigm for the third millennium |
Q26863243 | Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments |
Q41061156 | Lactate transport in L6 skeletal muscle cells and vesicles: allosteric or multisite mechanism and functional membrane marker of differentiation |
Q36882190 | Lactate transport in heart in relation to myocardial ischemia |
Q33652197 | Lactate transport in skeletal muscle - role and regulation of the monocarboxylate transporter. |
Q50095883 | Lactic Acid: No Longer an Inert and End-Product of Glycolysis |
Q47955138 | Lactic acid efflux from white skeletal muscle is catalyzed by the monocarboxylate transporter isoform MCT3. |
Q34701707 | MCT2 expression and lactate influx in anorexigenic and orexigenic neurons of the arcuate nucleus. |
Q43970047 | MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain |
Q24548616 | Major facilitator superfamily |
Q46420405 | Mammalian fuel utilization during sustained exercise. |
Q37313443 | Mechanisms of the penetration of blood-borne substances into the brain |
Q34132189 | Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia |
Q44217967 | Metabolic costs induced by lactate in the toad Bufo marinus: new mechanism behind oxygen debt? |
Q40417740 | Metabolic fuel selection by intestinal epithelium |
Q38420759 | Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein |
Q34746073 | Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines. |
Q36654889 | Modulation of inflammatory cytokines and mitogen-activated protein kinases by acetate in primary astrocytes |
Q53359744 | Molecular imaging of prostate cancer. |
Q39205710 | Monocarboxylate 4 mediated butyrate transport in a rat intestinal epithelial cell line |
Q40155649 | Monocarboxylate transporter (MCT) mediates the transport of gamma-hydroxybutyrate in human kidney HK-2 cells |
Q48271101 | Monocarboxylate transporter (MCT1) abundance in brains of suckling and adult rats: a quantitative electron microscopic immunogold study |
Q33253559 | Monocarboxylate transporter 1 (MCT1) plays a direct role in short-chain fatty acids absorption in caprine rumen |
Q92506650 | Monocarboxylate transporters in cancer |
Q37187094 | Monocarboxylate transporters in the brain and in cancer. |
Q42374631 | Monocarboxylate transporters, blood lactate removal after supramaximal exercise, and fatigue indexes in humans. |
Q38165142 | Monocarboxylic acid transport |
Q34497858 | Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis |
Q28610034 | Mutations in MCT1 cDNA in patients with symptomatic deficiency in lactate transport |
Q42831188 | N-terminal protein sequence analysis of the rabbit erythrocyte lactate transporter suggests identity with the cloned monocarboxylate transport protein MCT1. |
Q91404681 | NBCe1 mediates the regulation of the NADH/NAD+ redox state in cortical astrocytes by neuronal signals |
Q71670931 | Non-ionic diffusion and carrier-mediated transport drive extracellullar pH regulation of mouse colonic crypts |
Q35158693 | Non-stationary 13C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation |
Q34230208 | O2-filled swimbladder employs monocarboxylate transporters for the generation of O2 by lactate-induced root effect hemoglobin |
Q33787924 | One hundred years of membrane permeability: does Overton still rule? |
Q33902405 | Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells |
Q36952136 | Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid |
Q36515067 | PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis |
Q44579705 | Perinatal and early postnatal changes in the expression of monocarboxylate transporters MCT1 and MCT2 in the rat forebrain |
Q46515638 | Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants. |
Q47388808 | Photoluminescence intensity ratio of Eu-conjugated lactates-A simple optical imaging technique for biomarker analysis for critical diseases |
Q47892655 | Preferential utilization of acetate by astrocytes is attributable to transport. |
Q24309043 | Presence and localization of three lactic acid transporters (MCT1, -2, and -4) in separated human granulocytes, lymphocytes, and monocytes |
Q79624383 | Propionate absorption associated with bicarbonate secretion in vitro in the mouse cecum |
Q46386518 | Protection by exogenous pyruvate through a mechanism related to monocarboxylate transporters against cell death induced by hydrogen peroxide in cultured rat cortical neurons. |
Q44881989 | Pure pressure stress increased monocarboxylate transporter in human aortic smooth muscle cell membrane |
Q77678077 | Purification of the lysosomal sialic acid transporter. Functional characteristics of a monocarboxylate transporter |
Q38714417 | Pyruvate antioxidant roles in human fibroblasts and embryonic stem cells |
Q39375963 | Pyruvate incubation enhances glycogen stores and sustains neuronal function during subsequent glucose deprivation |
Q35753977 | Pyruvate protects mitochondria from oxidative stress in human neuroblastoma SK-N-SH cells |
Q48579857 | Pyruvate protects neurons against hydrogen peroxide-induced toxicity |
Q43594208 | Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity. |
Q40877599 | Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated cell death |
Q33875107 | Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture |
Q47983098 | Relationship between blood lactate and cortical excitability between taekwondo athletes and non-athletes after hand-grip exercise |
Q44062965 | Relative distribution of three major lactate transporters in frozen human tissues and their localization in unfixed skeletal muscle |
Q64112306 | Research Trends and Hotspots Analysis Related to Monocarboxylate Transporter 1: A Study Based on Bibliometric Analysis |
Q35101858 | Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals |
Q44646909 | Restitution of the bullfrog gastric mucosa is dependent on a DIDS-inhibitable pathway not related to HCO3- ion transport |
Q45251314 | Role of USF1 and USF2 as potential repressor proteins for human intestinal monocarboxylate transporter 1 promoter |
Q34959832 | Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle |
Q33854710 | Role of monocarboxylate transporters in drug delivery to the brain |
Q33973728 | Role of plasma membrane transporters in muscle metabolism. |
Q27013026 | Roles of interstitial fluid pH in diabetes mellitus: Glycolysis and mitochondrial function |
Q100165299 | SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol |
Q44631955 | Salicylic acid transport in Ricinus communis involves a pH-dependent carrier system in addition to diffusion |
Q79733993 | Salicylic acid, an ambimobile molecule exhibiting a high ability to accumulate in the phloem |
Q34274838 | Scientific side trips: six excursions from the beaten path |
Q24317364 | Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico |
Q55349805 | Short-Chain Fatty Acid Transporters: Role in Colonic Homeostasis. |
Q33985125 | Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems |
Q39956798 | Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer |
Q38922312 | Solute Carriers in the Blood-Brain Barier: Safety in Abundance |
Q41147406 | Stereoselective and carrier-mediated transport of monocarboxylic acids across Caco-2 cells |
Q38299941 | Structure and function of thyroid hormone plasma membrane transporters |
Q41985536 | Studies of the membrane topology of the rat erythrocyte H+/lactate cotransporter (MCT1). |
Q28580055 | Studies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycle |
Q30042971 | Substrate-analogous inhibitors exert antimalarial action by targeting the Plasmodium lactate transporter PfFNT at nanomolar scale |
Q24642366 | Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1 |
Q52339897 | Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate. |
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Q38448304 | Synthesis and structure-activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors. |
Q36998098 | The Expression of Glut-1, CAIX, and MCT4 in Mucinous Carcinoma. |
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Q28203497 | The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond |
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Q35126615 | The concept of maximal lactate steady state: a bridge between biochemistry, physiology and sport science |
Q27938853 | The conserved sequence NXX[S/T]HX[S/T]QDXXXT of the lactate/pyruvate:H(+) symporter subfamily defines the function of the substrate translocation pathway |
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Q34433285 | The genetic variation in monocarboxylic acid transporter 2 (MCT2) has functional and clinical relevance with male infertility |
Q28576555 | The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein |
Q91595470 | The intracellular parasite Toxoplasma gondii harbors three druggable FNT-type formate and l-lactate transporters in the plasma membrane |
Q42829884 | The kinetics, substrate and inhibitor specificity of the lactate transporter of Ehrlich-Lettre tumour cells studied with the intracellular pH indicator BCECF. |
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Q34237222 | The monocarboxylate transporter family--Structure and functional characterization |
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Q36713248 | cDNA cloning of MCT2, a second monocarboxylate transporter expressed in different cells than MCT1. |
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