Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies

scientific article

Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.00429-10
P932PMC publication ID2937563
P698PubMed publication ID20584987

P50authorGeorg StoecklinQ43093535
P2093author name stringSevim Ozgur
Marina Chekulaeva
P2860cites workHuman Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcriptionQ24293751
Multiple processing body factors and the ARE binding protein TTP activate mRNA decappingQ24299303
A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodiesQ24537397
The hDcp2 protein is a mammalian mRNA decapping enzymeQ24538218
The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic fociQ24540163
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structuresQ24543188
Stress granule assembly is mediated by prion-like aggregation of TIA-1Q24559953
A Sm-like protein complex that participates in mRNA degradationQ24630673
Cytoplasmic foci are sites of mRNA decay in human cellsQ24677437
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodiesQ24681266
Translational repression by the oocyte-specific protein P100 in Xenopus.Q48698437
T-cell Intracellular Antigen-1 (TIA-1)-induced Translational Silencing Promotes the Decay of Selected mRNAsQ57083964
Identification of PatL1, a human homolog to yeast P body component Pat1Q58128331
Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiaeQ27930894
Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing BodiesQ27931286
A role for Q/N-rich aggregation-prone regions in P-body localization.Q27932050
The two proteins Pat1p (Mrt1p) and Spb8p interact in vivo, are required for mRNA decay, and are functionally linked to Pab1pQ27935345
The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5pQ27935384
Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAsQ27936762
TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elementsQ28117692
Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1Q28118675
Relief of microRNA-mediated translational repression in human cells subjected to stressQ28246349
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteinsQ28254176
Prions as adaptive conduits of memory and inheritanceQ28254236
Inhibition of translational initiation by Let-7 MicroRNA in human cellsQ28265842
The highways and byways of mRNA decayQ28284717
A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substratesQ28304600
Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cellsQ28508125
General translational repression by activators of mRNA decappingQ29614567
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granulesQ29615265
Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcriptQ29615273
The enzymes and control of eukaryotic mRNA turnoverQ29616563
Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structureQ29620098
ARE-mRNA degradation requires the 5'-3' decay pathway.Q34360717
Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elementsQ34364003
The yeast cytoplasmic LsmI/Pat1p complex protects mRNA 3' termini from partial degradationQ34613034
Analysis of P-body assembly in Saccharomyces cerevisiaeQ35810641
Posttranscriptional mechanisms regulating the inflammatory response.Q36472030
Pat1 contains distinct functional domains that promote P-body assembly and activation of decappingQ36483383
Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiaeQ36563128
Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) during Caenorhabditis elegans oogenesisQ36817904
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cellsQ37487108
A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in DrosophilaQ37491669
The decapping activator Lsm1p-7p-Pat1p complex has the intrinsic ability to distinguish between oligoadenylated and polyadenylated RNAsQ38301581
Translational repression and specific RNA binding by the coat protein of the Pseudomonas phage PP7.Q38301859
HPat provides a link between deadenylation and decapping in metazoaQ40097032
P-body formation is a consequence, not the cause, of RNA-mediated gene silencingQ42738042
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
PAT1 homolog 2Q21120390
PAT1 homolog 1, processing body mRNA decay factorQ21130406
P304page(s)4308-4323
P577publication date2010-06-28
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleHuman Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies
P478volume30