TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements

scientific journal article

TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1101/GAD.1494707
P3181OpenCitations bibliographic resource ID1655307
P932PMC publication ID1820945
P698PubMed publication ID17369404
P5875ResearchGate publication ID6438866

P50authorJens Lykke-AndersenQ55154882
P2093author name stringTobias M Franks
P2860cites workA role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decayQ24679242
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodiesQ24681266
RNA granulesQ24683783
Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing BodiesQ27931286
Yeast Sm-like proteins function in mRNA decapping and decayQ27936322
Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAsQ27936762
Targeting of aberrant mRNAs to cytoplasmic processing bodiesQ27939158
Involvement of microRNA in AU-rich element-mediated mRNA instabilityQ28118466
Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1Q28118675
Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnoverQ28215400
Relief of microRNA-mediated translational repression in human cells subjected to stressQ28246349
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodiesQ28252216
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machineryQ28264688
Inhibition of translational initiation by Let-7 MicroRNA in human cellsQ28265842
Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodiesQ28270553
Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificitiesQ28274328
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnoverQ28281490
Disruption of GW bodies impairs mammalian RNA interferenceQ28281500
Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin familyQ28585872
A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiencyQ28589649
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alphaQ28594475
AU-rich elements: characterization and importance in mRNA degradationQ29547896
General translational repression by activators of mRNA decappingQ29614567
RNA stabilization by the AU-rich element binding protein, HuR, an ELAV proteinQ29615186
Processing bodies require RNA for assembly and contain nontranslating mRNAsQ29615264
The cap-to-tail guide to mRNA turnoverQ29619835
Premature translational termination triggers mRNA decappingQ29620198
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAsQ29620269
Differential distribution of exosome subunits at the nuclear lamina and in cytoplasmic foci.Q30476869
Cap-independent polysomal association of natural mRNAs encoding c-myc, BiP, and eIF4G conferred by internal ribosome entry sitesQ31957370
A resource for large-scale RNA-interference-based screens in mammals.Q33200135
Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnoverQ33954794
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1.Q34097417
ARE-mRNA degradation requires the 5'-3' decay pathway.Q34360717
SMG7 acts as a molecular link between mRNA surveillance and mRNA decayQ34368226
Translational repression by RNA-binding protein TIARQ34520016
The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritisQ21195674
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.Q22010036
Interactions of CCCH zinc finger proteins with mRNA. Binding of tristetraprolin-related zinc finger proteins to Au-rich elements and destabilization of mRNAQ22253466
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codonQ24290775
AU binding proteins recruit the exosome to degrade ARE-containing mRNAsQ24291926
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elementsQ24292126
Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAsQ24292131
Multiple processing body factors and the ARE binding protein TTP activate mRNA decappingQ24299303
GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferationQ24307714
Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolinQ24323168
An unconventional human Ccr4-Caf1 deadenylase complex in nuclear cajal bodiesQ24337378
Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnoverQ24534314
A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodiesQ24537397
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencingQ24537488
The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic fociQ24540163
The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodiesQ24540223
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structuresQ24543188
Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayQ24548948
A role for the P-body component GW182 in microRNA functionQ24669847
Cytoplasmic foci are sites of mRNA decay in human cellsQ24677437
Stress granules and processing bodies are dynamically linked sites of mRNP remodelingQ24678779
AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factorsQ35003442
Formation of GW bodies is a consequence of microRNA genesisQ35016215
The control of mRNA stability in response to extracellular stimuli.Q35042665
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblastsQ35221409
RNA decapping inside and outside of processing bodies.Q36131538
Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAsQ36796132
Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway.Q39453060
Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA.Q40980265
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegansQ47068671
The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development.Q52559820
AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradationQ71119789
Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stabilityQ73520889
P433issue6
P921main subjectZFP36 ring finger proteinQ21110024
ZFP36 ring finger protein like 1Q21120026
positive regulation of intracellular mRNA localizationQ22301073
P304page(s)719-735
P577publication date2007-03-01
P1433published inGenes & DevelopmentQ1524533
P1476titleTTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements
P478volume21

Reverse relations

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