Role of pro-IGF-II processing by proprotein convertase 4 in human placental development

scientific article

Role of pro-IGF-II processing by proprotein convertase 4 in human placental development is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2005PNAS..10211047Q
P356DOI10.1073/PNAS.0502357102
P3181OpenCitations bibliographic resource ID3016763
P932PMC publication ID1182422
P698PubMed publication ID16040806
P5875ResearchGate publication ID7704328

P50authorBenjamin K TsangQ42713839
Majambu MbikayQ56876535
P2093author name stringAndrée Gruslin
Qing Qiu
Ajoy Basak
P2860cites workThe testicular germ-cell protease PC4 is also expressed in macrophage-like cells of the ovaryQ28115403
Immunohistochemical localization of carboxypeptidases E and D in the human placenta and umbilical cordQ28288842
The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functionsQ28305292
Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet beta-cells and enhances insulin secretionQ28364649
Impaired fertility in mice deficient for the testicular germ-cell protease PC4Q28505494
Role of insulin-like growth factors in embryonic and postnatal growthQ29620034
Polyarginines are potent furin inhibitorsQ30910938
Carboxypeptidases from A to z: implications in embryonic development and Wnt bindingQ34107145
Placental-specific IGF-II is a major modulator of placental and fetal growth.Q34135795
Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumorsQ34301972
Placental-specific insulin-like growth factor 2 (Igf2) regulates the diffusional exchange characteristics of the mouse placentaQ34332616
Ten years of protein kinase B signalling: a hard Akt to followQ34432885
Born small for gestational age: increased risk of type 2 diabetes, hypertension and hyperlipidaemia in adulthoodQ35085702
The insulin-like growth factors and feto-placental growthQ35226316
Serum "big insulin-like growth factor II" from patients with tumor hypoglycemia lacks normal E-domain O-linked glycosylation, a possible determinant of normal propeptide processingQ36377719
Amino acid sequence of a variant pro-form of insulin-like growth factor II.Q37687829
The identification of O-glycosylated precursors of insulin-like growth factor IIQ38329271
Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migrationQ40538973
Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK.Q40786394
Deficient processing and activity of type I insulin-like growth factor receptor in the furin-deficient LoVo-C5 cellsQ41011757
Post-translational processing of the insulin-like growth factor-2 precursor. Analysis of O-glycosylation and endoproteolysisQ41026364
Eukaryotic protein processing: endoproteolysis of precursor proteinsQ41628982
Enzymic characterization in vitro of recombinant proprotein convertase PC4.Q41818572
Biophysical and biological properties of naturally occurring high molecular weight insulin-like growth factor II variantsQ47313772
Preterm delivery and low birth weight--a dire legacyQ47341886
Early pregnancy levels of pregnancy-associated plasma protein a and the risk of intrauterine growth restriction, premature birth, preeclampsia, and stillbirthQ47864591
Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoformsQ48084183
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
The relation between human fetal growth and fetal blood levels of insulin-like growth factors I and II, their binding proteins, and receptorsQ71628625
Functional role of cell surface integrins on human trophoblast cell migration: regulation by TGF-beta, IGF-II, and IGFBP-1Q71684241
Fetal and maternal plasma insulin-like growth factors and binding proteins in pregnancies with appropriate or retarded fetal growthQ73405986
Secretion of noncomplexed 'Big' (10-18 kD) forms of insulin-like growth factor-II by 12 soft tissue sarcoma cell linesQ73567442
Use of site-specific antibodies to characterize the circulating form of big insulin-like growth factor II in patients with hepatitis C-associated osteosclerosisQ74572203
P433issue31
P407language of work or nameEnglishQ1860
P921main subjectprotein processingQ14862717
Proprotein convertase subtilisin/kexin type 4Q21133339
P304page(s)11047-11052
P577publication date2005-07-22
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleRole of pro-IGF-II processing by proprotein convertase 4 in human placental development
P478volume102

Reverse relations

cites work (P2860)
Q39213186AKT isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans
Q28589081Alteration in the processing of the ACRBP/sp32 protein and sperm head/acrosome malformations in proprotein convertase 4 (PCSK4) null mice
Q35927951Ancient and continuing Darwinian selection on insulin-like growth factor II in placental fishes
Q35080133Characterization of IGF-II isoforms in binge eating disorder and its group psychological treatment
Q34280644Critical growth factors and signalling pathways controlling human trophoblast invasion
Q41483780Doege-Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal.
Q28580888Effect of nicotine exposure during pregnancy and lactation on maternal, fetal, and postnatal rat IGF-II profile
Q28593525Enzymatic activity of sperm proprotein convertase is important for mammalian fertilization
Q36287656Fibrinous tumor of the pleura: an orphan disease lost in translation
Q42881111From genes to circuits and behaviors: Neuropeptides expand the coding potential of the nervous system
Q46240548IGF and insulin receptor signaling in breast cancer.
Q34740473IGFBP-4 and -5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells
Q46259020Identification and expression analysis of cDNA encoding insulin-like growth factor 2 in horses.
Q36282129Inhibitors of proprotein convertases
Q42630582Insulin-like growth factor 2 rescues aging-related memory loss in rats
Q89567665Insulin-like growth factor-II and bioactive proteins containing a part of the E-domain of pro-insulin-like growth factor-II
Q37016791Maternal protein restriction regulates IGF2 system in placental labyrinth
Q28076524Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?
Q64923496Non-islet Cell Hypoglycemia: Case Series and Review of the Literature.
Q38880458Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth.
Q37358452Proprotein convertase subtilisin/kexin type 4 in mammalian fertility: a review.
Q36411469Role of human cytomegalovirus in the proliferation and invasion of extravillous cytotrophoblasts isolated from early placentae
Q35386765Self-assembling peptide nanofibers coupled with neuropeptide substance P for bone tissue engineering
Q37336840Surgically cured hypoglycemia secondary to pleural solitary fibrous tumour: case report and update review on the Doege-Potter syndrome
Q38017196The biology and therapeutic targeting of the proprotein convertases
Q34494973The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth.
Q39631375The precursor to the germ cell-specific PCSK4 proteinase is inefficiently activated in transfected somatic cells: evidence of interaction with the BiP chaperone.
Q34169463What lies ahead for the proprotein convertases?
Q34280658Wingless (Wnt)-3A induces trophoblast migration and matrix metalloproteinase-2 secretion through canonical Wnt signaling and protein kinase B/AKT activation

Search more.