SMN interacts with a novel family of hnRNP and spliceosomal proteins

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SMN interacts with a novel family of hnRNP and spliceosomal proteins is …
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scholarly articleQ13442814

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P356DOI10.1093/EMBOJ/20.19.5443
P3181OpenCitations bibliographic resource ID1426587
P932PMC publication ID125643
P698PubMed publication ID11574476
P5875ResearchGate publication ID232782144

P50authorZissimos MourelatosQ37383021
P2093author name stringG Dreyfuss
L Abel
N Kataoka
J Yong
P2860cites workThe double lives of shuttling mRNA binding proteinsQ33913906
Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structureQ34332907
The survival motor neuron protein in spinal muscular atrophyQ34435656
SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins.Q35641208
The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstreamQ36570481
Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryosQ36578997
Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assemblyQ37578982
Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophyQ38313528
Characterization of the Schizosaccharomyces pombe orthologue of the human survival motor neuron (SMN) proteinQ38313541
The Schizosaccharomyces pombe protein Yab8p and a novel factor, Yip1p, share structural and functional similarity with the spinal muscular atrophy-associated proteins SMN and SIP1.Q38313544
A mouse model for spinal muscular atrophyQ38316939
Nucleocytoplasmic transport and snRNP assemblyQ40776319
Correlation between severity and SMN protein level in spinal muscular atrophyQ41102726
When is a deletion not a deletion? When it is convertedQ43105061
The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophyQ43569750
The Caenorhabditis elegans orthologue of the human gene responsible for spinal muscular atrophy is a maternal product critical for germline maturation and embryonic viability.Q47068856
Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins.Q54389649
Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type IIIQ60215386
The survival motor neuron protein of Schizosacharomyces pombe. Conservation of survival motor neuron interaction domains in divergent organismsQ73804884
A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicingQ22008514
A novel heterogeneous nuclear ribonucleoprotein-like protein interacts with NS1 of the minute virus of miceQ22008520
Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicingQ22009171
Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gemsQ22010941
Gemin4. A novel component of the SMN complex that is found in both gems and nucleoliQ22253358
Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasmQ24290398
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complexQ24311408
Interaction between the human nuclear cap-binding protein complex and hnRNP FQ24314610
The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteinsQ24316085
The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesisQ24316121
Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP PQ24318358
A novel nuclear structure containing the survival of motor neurons proteinQ24324247
A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcriptsQ24339390
hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cellsQ24554786
Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K proteinQ24630724
A functional interaction between the survival motor neuron complex and RNA polymerase IIQ24674951
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Conserved structures and diversity of functions of RNA-binding proteinsQ27861066
Mechanical devices of the spliceosome: motors, clocks, springs, and thingsQ27938081
A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complexQ28142236
Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteinsQ28143590
Spinal muscular atrophyQ28251310
Monoclonal antibody characterization of the C proteins of heterogeneous nuclear ribonucleoprotein complexes in vertebrate cellsQ28263029
Identification and characterization of a spinal muscular atrophy-determining geneQ29547495
hnRNP proteins and the biogenesis of mRNAQ29547911
hnRNP complexes: composition, structure, and functionQ29619428
Protein functions in pre-mRNA splicingQ29620262
Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2Q29620278
A cell system with targeted disruption of the SMN gene: functional conservation of the SMN protein and dependence of Gemin2 on SMN.Q30976876
A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers.Q33890073
Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN).Q33905442
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectspliceosomeQ915868
P304page(s)5443-5452
P577publication date2001-10-01
P1433published inThe EMBO JournalQ1278554
P1476titleSMN interacts with a novel family of hnRNP and spliceosomal proteins
P478volume20

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