Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells

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Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells is …
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scholarly articleQ13442814

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P819ADS bibcode2006PNAS..103.6326U
P356DOI10.1073/PNAS.0601223103
P932PMC publication ID1458877
P698PubMed publication ID16606835
P5875ResearchGate publication ID7172901

P50authorColin D FunkQ56957754
Barbara UzonyiQ55427920
P2093author name stringAndreas J R Habenicht
Michael Beer
Dörte Radke
Katharina Lötzer
Markus Hildner
Steffen Jahn
Rüdiger Vollandt
Jilly F Evans
Ellen Bretschneider
Cornelia Kramer
P2860cites workCharacterization of the human cysteinyl leukotriene CysLT1 receptorQ22010199
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Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesisQ28205296
MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditionsQ59064735
Transcellular sulfidopeptide leukotriene biosynthetic capacity of vascular cellsQ69352974
Leukotriene A4, and not leukotriene B4, is the main 5-lipoxygenase metabolite released by bovine leukocytesQ71215398
Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cellsQ73686895
The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressinQ73822798
Leukotriene B4 receptor BLT1 mediates early effector T cell recruitmentQ73886545
Active tissue factor in blood?Q80937513
Tissue factor activity in whole bloodQ81157689
Prostaglandins and leukotrienes: advances in eicosanoid biologyQ28208246
Transduction of receptor signals by beta-arrestinsQ28246395
Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cellsQ28249984
Role of tissue factor in hemostasis, thrombosis, and vascular developmentQ28259220
Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesisQ28284677
Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stressQ28512203
The ADAMTS metalloproteinasesQ29544428
Chemokines--chemotactic cytokines that mediate inflammationQ29616433
Thrombin signalling and protease-activated receptorsQ29619601
Characterization of the human cysteinyl leukotriene 2 receptorQ30305734
Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammationQ30433441
High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis.Q33939860
Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and InflammationQ34254403
COX-2 and beyond: Approaches to prostaglandin inhibition in human diseaseQ34282832
Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressureQ34368064
Leukotriene receptors: classification, gene expression, and signal transductionQ34720495
Cysteinyl leukotriene receptorsQ34995382
Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responsesQ35841909
The NR4A subfamily of nuclear receptors: new early genes regulated by growth factors in vascular cells.Q36017199
Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxiaQ36174464
Leukotriene modifiers as potential therapeutics for cardiovascular diseaseQ36205826
The 5-lipoxygenase pathway in arterial wall biology and atherosclerosisQ36218949
Protease-activated receptors in hemostasis, thrombosis and vascular biologyQ36230881
Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosisQ36853612
The combined role of P- and E-selectins in atherosclerosisQ37387115
Growth factor-responsive genes in fibroblasts.Q37831984
Role of ADAMTS-1 in atherosclerosis: remodeling of carotid artery, immunohistochemistry, and proteolysis of versican.Q40493102
Histamine induces nuclear factor of activated T cell-mediated transcription and cyclosporin A-sensitive interleukin-8 mRNA expression in human umbilical vein endothelial cells.Q41020235
Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes.Q42051351
Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate 5-lipoxygenase-dependent circuits of inflammation and atherogenesis.Q44484476
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.Q45025551
Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in miceQ45029761
PAR1 cleavage and signaling in response to activated protein C and thrombin.Q46022355
Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4.Q48230335
Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues.Q52005840
Calcium-independent calcineurin regulation.Q55036788
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)6326-31
P577publication date2006-04-18
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells
P478volume103

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