Signaling by the cysteinyl-leukotriene receptor 2. Involvement in chemokine gene transcription

scientific article published on 29 November 2007

Signaling by the cysteinyl-leukotriene receptor 2. Involvement in chemokine gene transcription is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M608197200
P698PubMed publication ID18048362

P50authorMarek Rola-PleszczynskiQ41603821
P2093author name stringCharles Thompson
Jana Stankova
Patrick P McDonald
Ynuk Bossé
Pierre Larivée
Alexandre Cloutier
Caroline Poisson
P2860cites workCharacterization of the human cysteinyl leukotriene CysLT1 receptorQ22010199
The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptorQ22254682
Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cellsQ24546541
Activation of IkappaB kinase beta by protein kinase C isoformsQ24554525
Rapid and simple comparison of messenger RNA levels using real-time PCR.Q25257674
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
NF-kappaB: a multifaceted transcription factor regulated at several levelsQ28285466
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1Q28291340
Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8Q28609808
Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa BQ28646362
Signaling to NF-kappaBQ29547844
Shaping the nuclear action of NF-kappaBQ29614600
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa BQ29618194
Characterization of the human cysteinyl leukotriene 2 receptorQ30305734
Control of CYP11B2 gene expression through differential regulation of its promoter by atypical and conventional protein kinase C isoformsQ31685458
Leukotrienes, leukotriene receptor antagonists and leukotriene synthesis inhibitors in asthma: an update. Part II: clinical studies with leukotriene receptor antagonists and leukotriene synthesis inhibitors in asthmaQ33667716
Dominant expression of the CysLT2 receptor accounts for calcium signaling by cysteinyl leukotrienes in human umbilical vein endothelial cellsQ34207335
Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activationQ34217097
Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocationQ34218574
A cysteinyl leukotriene 2 receptor variant is associated with atopy in the population of Tristan da CunhaQ34265744
A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthmaQ34357764
The IKK/NF-kappa B pathwayQ34487840
Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instabilityQ34601356
Nuclear factor-kappaB as a therapeutic target in critical care medicineQ35052442
Emerging and diverse roles of protein kinase C in immune cell signallingQ35564874
Protein kinase C and beyondQ35849920
A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activationQ36694624
Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseasesQ37888849
Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cellsQ38325239
CysLT1 receptor engagement induces activator protein-1- and NF-kappaB-dependent IL-8 expressionQ40261154
Activation and translocation of PKCdelta is necessary for VEGF-induced ERK activation through KDR in HEK293T cellsQ40492864
The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cellsQ40834542
Transcription factors and asthmaQ40846857
Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significanceQ41730041
Release of leukotrienes in patients with bronchial asthmaQ43414768
Heterogeneity of airway inflammation in persistent asthma : evidence of neutrophilic inflammation and increased sputum interleukin-8.Q43604750
Differential leukotriene receptor expression and calcium responses in endothelial cells and macrophages indicate 5-lipoxygenase-dependent circuits of inflammation and atherogenesis.Q44484476
Expression of cysteinyl leukotriene synthetic and signalling proteins in inflammatory cells in active seasonal allergic rhinitisQ44602473
Protein kinase Cdelta mediates lysophosphatidic acid-induced NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cellsQ44997658
Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in miceQ45029761
A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.Q45142085
Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challengeQ45402860
A novel protein kinase C (PKCepsilon) is required for fMet-Leu-Phe-induced activation of NF-kappaB in human peripheral blood monocytesQ46421293
Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activationQ46510703
Essential role of c-Jun induction and coactivator p300 in epidermal growth factor-induced gene expression of cyclooxygenase-2 in human epidermoid carcinoma A431 cellsQ47238901
Induced Sputum Eicosanoid Concentrations in AsthmaQ55094021
Leukotrienes as Mediators of Airway ObstructionQ57240752
Sputum Cysteinyl Leukotrienes Increase 24 Hours after Allergen Inhalation in Atopic AsthmaticsQ57415809
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1974-1984
P577publication date2007-11-29
P1433published inJournal of Biological ChemistryQ867727
P1476titleSignaling by the cysteinyl-leukotriene receptor 2. Involvement in chemokine gene transcription
P478volume283

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cites work (P2860)
Q35212880A genome-wide association study in catfish reveals the presence of functional hubs of related genes within QTLs for columnaris disease resistance
Q30234292Alleviating Promotion of Inflammation and Cancer Induced by Nonsteroidal Anti-Inflammatory Drugs
Q28582197CysLT2 receptor-mediated AQP4 up-regulation is involved in ischemic-like injury through activation of ERK and p38 MAPK in rat astrocytes
Q54629468Cysteinyl-leukotrienes induce vascular endothelial growth factor production in human monocytes and bronchial smooth muscle cells.
Q34145036Differential Signaling Defects Associated with the M201V Polymorphism in the Cysteinyl Leukotriene Type 2 Receptor
Q33595066Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection.
Q57099569Effects of a cysteinyl leukotriene dual 1/2 receptor antagonist on antigen-induced airway hypersensitivity and airway inflammation in a guinea pig asthma model
Q28074285Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer
Q37208991Expanding roles for leukotrienes in airway inflammation
Q34173916Expression of Leukotriene Receptors in the Rat Dorsal Root Ganglion and the Effects on Pain Behaviors
Q42936280Inflammation, Cancer and Oxidative Lipoxygenase Activity are Intimately Linked
Q34420971Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue.
Q33656058Protein kinases A and C regulate receptor-mediated increases in cAMP in rabbit erythrocytes
Q34110714Regulation of cysteinyl leukotriene receptor 2 expression--a potential anti-tumor mechanism
Q42948998Specific NFkappaB subunit activation and kinetics of cytokine induction in adenoviral keratitis.
Q28115307The multiple-specificity landscape of modular peptide recognition domains
Q38864535Transcriptional and posttranscriptional regulation of CXCL8/IL-8 gene expression induced by connective tissue growth factor

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