Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation

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Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation is …
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scholarly articleQ13442814

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P356DOI10.1172/JCI117921
P8608Fatcat IDrelease_ddjfv6nzvzgybmjbukpysi5w5u
P932PMC publication ID295843
P698PubMed publication ID7537762
P5875ResearchGate publication ID15660875

P2093author name stringG A Zimmerman
S M Prescott
T M McIntyre
A S Weyrich
R P McEver
P2860cites workGMP-140 (P-selectin/CD62) binds to chronically stimulated but not resting CD4+ T lymphocytes and regulates their production of proinflammatory cytokinesQ67539003
LFA-3, CD44, and CD45: Physiologic Triggers of Human Monocyte TNF and IL-1 ReleaseQ67670594
A sensitive ELISA for the detection of human monocyte chemoattractant protein-1 (MCP-1)Q68074597
Expression of ICAM-R (ICAM-3), a novel counter-receptor for LFA-1, in rheumatoid and nonrheumatoid synovium. Comparison with other adhesion moleculesQ71627655
Time course of coronary vascular endothelial adhesion molecule expression during reperfusion of the ischemic feline myocardiumQ71669842
Intercellular adhesion molecule-1 mediates the expression of monocyte-derived MIP-1 alpha during monocyte-endothelial cell interactionsQ72669905
Expression cloning of a functional glycoprotein ligand for P-selectinQ24304912
Cytoplasmic domain of P-selectin (CD62) contains the signal for sorting into the regulated secretory pathwayQ24642212
Signal transduction from the extracellular matrixQ24675031
Cloning and characterization of a new intercellular adhesion molecule ICAM-RQ28118854
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient miceQ28507847
The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamineQ28644133
Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathwayQ28756455
Inflammatory roles of P-selectinQ34169805
Endothelial cell interactions with granulocytes: tethering and signaling moleculesQ35325829
Monocyte-endothelial adhesion in chronic rheumatoid arthritis. In situ detection of selectin and integrin-dependent interactionsQ35610854
In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injuryQ35610891
P-selectin induces the expression of tissue factor on monocytesQ35746146
Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophilsQ36529236
Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophilsQ36532906
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cellsQ36533177
The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytesQ36534966
Contact and adhesive specificities in the associations, migrations, and targeting of cells and axonsQ36750000
Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene inductionQ37219576
Adhesion protein GMP140 inhibits superoxide anion release by human neutrophilsQ37441993
NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene.Q38304810
Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectinQ38317579
Characterization of a specific ligand for P-selectin on myeloid cells. A minor glycoprotein with sialylated O-linked oligosaccharidesQ38318413
Selectins.Q40388550
Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor systemQ40835501
Rapid induction of arachidonic acid release by monocyte chemotactic protein-1 and related chemokines. Role of Ca2+ influx, synergism with platelet-activating factor and significance for chemotaxisQ41486828
Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytesQ41508812
Rapid neutrophil adhesion to activated endothelium mediated by GMP-140.Q41743717
Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1.Q42159025
Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140Q46852557
Visualization of the endogenous NF-kappa B p50 subunit in the nucleus of follicular dendritic cells in germinal centers.Q54041687
Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes.Q64955019
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
chemotaxisQ658145
P304page(s)2297-2303
P577publication date1995-05-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMonocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation
P478volume95

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cites work (P2860)
Q7780410912-Hydroxyeicosatetraenoic acid upregulates P-selectin-induced tissue factor activity on monocytes
Q4097188113-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis
Q92740891A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation
Q37364649Absence of P-selectin delays fatty streak formation in mice
Q33894973Activated Monocytes Enhance Platelet-Driven Contraction of Blood Clots via Tissue Factor Expression
Q41812828Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2 and Cytokines
Q37786647Activated platelets and atherosclerosis
Q37353355Activated platelets signal chemokine synthesis by human monocytes
Q73109008Activation of human monocytes for enhanced production of interleukin 8 during transendothelial migration in vitro
Q44227243Activation of vascular cells by PAF-like lipids in oxidized LDL.
Q41676660Adhesion molecules in haemopoiesis
Q50526083Adhesive interaction between peripheral blood mononuclear cells and activated platelets in the presence of anti-human leukocyte antigen Class I alloantibody causes production of IL-1β and IL-8.
Q36395085Alloantibody induced platelet responses in transplants: potent mediators in small packages
Q57999487Anti-P-selectin antibody decreases inflammation and thrombus formation in venous thrombosis
Q82223456Anti-inflammatory influence of P-selectin on human mononuclear cells
Q35546879Arterial thrombosis for the interventional cardiologist: From adhesion molecules and coagulation factors to clinical therapeutics
Q37130166Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: a pilot study
Q39295923Association of platelet activation markers with recurrence of atrial fibrillation after pulmonary vein isolation
Q37132791Beyond platelet inhibition: potential pleiotropic effects of ADP-receptor antagonists
Q33394357Beyond thrombosis: the versatile platelet in critical illness
Q30514562Cationic PAMAM dendrimers disrupt key platelet functions.
Q33943133Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes
Q45944125Cell type- and developmental stage-specific activation of NF-kappaB by fMet-Leu-Phe in myeloid cells.
Q28195775Changes in platelet P-selectin and in plasma C-reactive protein in acute atherosclerotic ischemic stroke treated with a loading dose of clopidogrel
Q73153331Chronic venous insufficiency is associated with increased platelet and monocyte activation and aggregation
Q28218124Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease
Q34019915Complement as a mediator of vascular inflammation and activation in allografts
Q30442280Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation
Q73258026Cross-talk between cell adhesion molecules regulates the migration velocity of neutrophils
Q40261154CysLT1 receptor engagement induces activator protein-1- and NF-kappaB-dependent IL-8 expression
Q74014832Density-dependent induction of TNF-alpha release from human monocytes by immobilized P-selectin
Q35877953Detection of circulating platelet-monocyte complexes in persons infected with human immunodeficiency virus type-1.
Q30829121Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response
Q39512417Divergent roles of tumor necrosis factor and platelet-activating factor in endotoxin-induced release of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta in chimpanzees
Q46694190Effects of eccentric exercise-induced muscle injury on blood levels of platelet activating factor (PAF) and other inflammatory markers
Q28346565Effects of ethanol on NF-kappaB activation, production of myeloid growth factors, and adhesive events in human endothelial cells
Q35043172Endovascular laser–tissue interactions and biological responses in relation to endovenous laser therapy
Q34916727Enterovirus 71 binding to PSGL-1 on leukocytes: VP1-145 acts as a molecular switch to control receptor interaction
Q34161044Events at the vascular wall: the molecular basis of inflammation
Q35039893Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling
Q41056352Expression of plasma platelet-activating factor acetylhydrolase is transcriptionally regulated by mediators of inflammation
Q90745245Extracorporeal Photochemotherapy: Mechanistic Insights Driving Recent Advances and Future Directions
Q36208502Genetic variant of Interleukin-18 gene is associated with the Frailty Index in the English Longitudinal Study of Ageing
Q30559534Genetic variants in platelet factor 4 modulate inflammatory and platelet activation biomarkers
Q35833625Higher levels of circulating monocyte-platelet aggregates are correlated with viremia and increased sCD163 levels in HIV-1 infection
Q44184963ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1.
Q24291709Immobilized IL-8 triggers progressive activation of neutrophils rolling in vitro on P-selectin and intercellular adhesion molecule-1
Q37736840Innate immune responses induced by lipopolysaccharide and lipoteichoic acid in primary goat mammary epithelial cells
Q34557811Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling
Q38299411Integrins regulate the intracellular distribution of eukaryotic initiation factor 4E in platelets. A checkpoint for translational control.
Q35545087Intervention in endotoxin shock by sulfatide (I3SO3-GalCer) with a concomitant reduction in tumor necrosis factor alpha production
Q47962358Intestinal NF-kappaB is activated, mainly as p50 homodimers, by platelet-activating factor
Q53171635Intracoronary platelet and monocyte activation status within platelet-monocyte complexes are determinants of inflammation in ST elevation myocardial infarction1.
Q43279071Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin
Q41986583Mapping the epitope of a functional P-selectin monoclonal antibody (LYP20) to a short complement-like repeat (SCR 4) domain: use of human-mouse chimaera and homologue-replacement mutagenesis
Q24629268Mechanisms involved in antibody- and complement-mediated allograft rejection
Q38635500Mechanisms of antibody-mediated acute and chronic rejection of kidney allografts
Q40419468Mechanisms of the adult respiratory distress syndrome: selectins
Q57574568Microvesicles from platelets: novel drivers of vascular inflammation
Q38400503Modulation of platelet and monocyte function by the chemokine fractalkine (CX3 CL1) in cardiovascular disease
Q41071075Molecular and cellular interactions mediating granulocyte accumulation in vivo
Q71815223Monocyte activation: rapid induction of alpha 1/beta 1 (VLA-1) integrin expression by lipopolysaccharide and interferon-gamma
Q46100164Monocyte chemoattractant protein 1 mediates glomerular macrophage infiltration in anti-GBM Ab GN.
Q37116502Monocyte-endothelial cell interactions in the development of atherosclerosis
Q34055659Monocyte-platelet interaction induces a pro-inflammatory phenotype in circulating monocytes
Q36274176New concepts of complement in allorecognition and graft rejection
Q33893036Noncovalent association of P-selectin glycoprotein ligand-1 and minimal determinants for binding to P-selectin
Q28348220Oxidized low-density lipoprotein and peroxisome-proliferator-activated receptor alpha down-regulate platelet-activating-factor receptor expression in human macrophages
Q73635468P-Selectin: Basic Aspects
Q40343152P-selectin chases a butterfly
Q37079911P-selectin cross-links PSGL-1 and enhances neutrophil adhesion to fibrinogen and ICAM-1 in a Src kinase-dependent, but GPCR-independent mechanism
Q39163377PSGL-1: A New Player in the Immune Checkpoint Landscape.
Q47573759Pathogen reduction treatment alters the immunomodulatory capacity of buffy coat-derived platelet concentrates
Q47887285Patients with venous stasis ulceration have increased monocyte-platelet aggregation
Q57292398Persistent platelet activation and apoptosis in virologically suppressed HIV-infected individuals
Q39787876Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment
Q34549341Platelet - leukocyte interactions: multiple links between inflammation, blood coagulation and vascular risk.
Q90485368Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes
Q38079764Platelet activating factor in heart failure: potential role in disease progression and novel target for therapy.
Q43186392Platelet activation in essential hypertension: implications for antiplatelet treatment
Q36368770Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18)
Q39403266Platelet, not endothelial, P-selectin expression contributes to generation of immunity in cutaneous contact hypersensitivity
Q36616764Platelet-leukocyte interactions in hemodialysis patients: culprit or bystander?
Q24793969Platelet-neutrophil conjugate formation is increased in diabetic women with cardiovascular disease
Q55279252Platelets Promote Brucella abortus Monocyte Invasion by Establishing Complexes With Monocytes.
Q38542454Platelets and Their Interactions with Other Immune Cells
Q37081746Platelets as cellular effectors of inflammation in vascular diseases
Q26739670Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases
Q35228522Platelets in early antibody-mediated rejection of renal transplants
Q40880206Platelets induce human umbilical vein endothelial cell proliferation through P-selectin
Q33411077Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway
Q90352007Platelets: inflammatory effector cells in the conflagration of cystic fibrosis lung disease
Q35101184Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum
Q35633718Platelet–leukocyte interactions link inflammatory and thromboembolic events in ischemic stroke
Q38095369Polymorphonuclear neutrophils and instability of the atherosclerotic plaque: a causative role?
Q28167462Prospective evaluation of the relationship between platelet-leukocyte conjugate formation and recurrent myocardial ischemia in patients with acute coronary syndromes
Q35541858Role of Monocytes in Atherogenesis
Q74045156Roles and relationship of macrophages and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in the ischemic and reperfused rat heart
Q37362400Selectin ligands: will the real ones please stand up?
Q49617012Selectins in cancer immunity.
Q36117363Selectins: initiators of leucocyte adhesion and signalling at the vascular wall
Q24675173Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets
Q40042544Signaling by the cysteinyl-leukotriene receptor 2. Involvement in chemokine gene transcription
Q30440643Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.
Q33559676Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice
Q41478095Structure and function of leukocyte chemoattractant receptors
Q70993034Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins
Q33698336Synthesis of sFlt-1 by platelet-monocyte aggregates contributes to the pathogenesis of preeclampsia
Q40064187Targeting the PSGL-1 pathway for immune modulation
Q73667757Terminal complement proteins in mediating processes of accelerated graft arteriosclerosis in cardiac transplants
Q28137923The MCP/eotaxin subfamily of CC chemokines
Q91528926The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathway
Q28077024The Role of CC-Chemokines in the Regulation of Angiogenesis
Q37387115The combined role of P- and E-selectins in atherosclerosis
Q24673214The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1
Q38373133The role of high-density lipoproteins in the regulation of angiogenesis.
Q37766875The role of monocytes in atherosclerotic coronary artery disease.
Q30437474The role of platelets in acute lung injury (ALI)
Q36677300The vessel wall and its interactions
Q33906710Therapeutic approaches to drug targets in atherosclerosis
Q47570271Treatment of platelets with riboflavin and ultraviolet light mediates complement activation and suppresses monocyte interleukin-12 production in whole blood
Q92314078Vascular Macrophages in Atherosclerosis
Q57999286Venous thrombosis prophylaxis by inflammatory inhibition without anticoagulation therapy
Q37367258Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking