Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum

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Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00281-011-0286-4
P932PMC publication ID4334392
P698PubMed publication ID21818701

P50authorGuy A ZimmermanQ62731484
Andrew WeyrichQ72089065
P2093author name stringRobert A Campbell
Adriana Vieira-de-Abreu
P2860cites workThe CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophagesQ22253155
Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophilsQ24293111
Platelet factor 4 is chemotactic for neutrophils and monocytesQ24302223
Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndromeQ24306498
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cellsQ24310570
Platelets mediate cytotoxic T lymphocyte-induced liver damageQ24604707
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritisQ24606320
Extracellular DNA traps promote thrombosis.Q24613579
Platelets amplify inflammation in arthritis via collagen-dependent microparticle productionQ24627618
A HaemAtlas: characterizing gene expression in differentiated human blood cellsQ24646314
Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by platelet-derived membrane vesiclesQ24655248
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanesQ24671911
The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1Q24673214
DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by plateletsQ24673797
Signal-dependent translation of a regulatory protein, Bcl-3, in activated human plateletsQ24675173
Gene-expression patterns predict phenotypes of immune-mediated thrombosisQ24685918
An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusionsQ79142074
Effect of serotonin on the differentiation of human monocytes into dendritic cellsQ79224138
Platelet-monocyte complex formation: effect of blocking PSGL-1 alone, and in combination with alphaIIbbeta3 and alphaMbeta2, in coronary stentingQ79370081
Human platelets synthesize and express functional tissue factorQ79906781
Induction of human monocyte interleukin (IL)-8 by fibrinogen through the toll-like receptor pathwayQ80597504
Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human plateletsQ80716085
Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10Q80947464
Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammationQ80967764
Clopidogrel inhibits platelet-leukocyte adhesion and platelet-dependent leukocyte activationQ81438721
Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factorQ81443659
Endotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanismQ81472583
Evidence of Toll-like receptor molecules on human plateletsQ81479217
Cooperation between platelet-derived CD154 and CD4+ T cells for enhanced germinal center formationQ81757066
Lentivirus degradation and DC-SIGN expression by human platelets and megakaryocytesQ82294742
Innate immunity. Recognizing the first responders. IntroductionQ82519818
Human platelets target dendritic cell differentiation and production of proinflammatory cytokinesQ83314817
Why human platelets fail to kill bacteriaQ83347743
Comparative genomics: fishing nets hemostatic catchQ83786815
LAD syndromes: FERMT3 kindles the signalQ83786840
Heparin-induced thrombocytopeniaQ84289360
Activated platelets rapidly up-regulate CD40L expression and can effectively mature and activate autologous ex vivo differentiated DCQ95824300
FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function.Q35804361
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signalingQ35883118
Platelet glycoprotein VI: its structure and functionQ35894228
Signaling to translational control pathways: diversity in gene regulation in inflammatory and vascular cells.Q36082283
Interactions of platelets with subendothelium and endotheliumQ36090987
Splicing misplacedQ36226892
Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets.Q36228070
Tissue factor: a mediator of inflammatory cell recruitment, tissue injury, and thrombus formation in experimental colitisQ36229495
Human platelet-mediated cytotoxicity against Toxoplasma gondii: role of thromboxaneQ36229800
Protease-activated receptors in hemostasis, thrombosis and vascular biologyQ36230881
Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets.Q36288115
Platelets in inflammation and atherogenesis.Q36328825
Enhancement of platelet response to immune complexes and IgG aggregates by lipid A-rich bacterial lipopolysaccharidesQ36339839
Platelet glycoprotein ibalpha is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18)Q36368770
Targeting platelet-leukocyte interactions: identification of the integrin Mac-1 binding site for the platelet counter receptor glycoprotein IbalphaQ36371735
The emerging role of platelets in adaptive immunityQ36379961
Circulating activated platelets reconstitute lymphocyte homing and immunity in L-selectin-deficient mice.Q36400175
Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell diseaseQ36428347
The interaction of bacterial pathogens with plateletsQ36482515
Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challengeQ36508925
Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophilsQ36532906
Platelets as immune cells: bridging inflammation and cardiovascular diseaseQ36699744
Immune regulation by microvascular endothelial cells: directing innate and adaptive immunity, coagulation, and inflammationQ36809550
Adhesion mechanisms in platelet functionQ36856340
Platelet integrins and immunoreceptorsQ36877378
Evolving functions of endothelial cells in inflammationQ36950913
Signal-dependent protein synthesis by activated platelets: new pathways to altered phenotype and function.Q36996283
Platelet factor 4 mediates inflammation in experimental cerebral malariaQ37016412
Platelet activation and atherothrombosisQ37031278
Functional expression of IgA receptor FcalphaRI on human plateletsQ37039019
Novel therapeutic targets at the platelet vascular interface.Q37049864
P2Y12 antagonism: promises and challengesQ37049867
Platelet-lymphocyte cross-talkQ37058252
The platelet activating factor (PAF) signaling cascade in systemic inflammatory responsesQ27693180
Neutrophil extracellular traps kill bacteriaQ27860996
Pattern recognition receptors and inflammationQ27861115
A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and functionQ28115628
CD40 Ligand-Dependent Maturation of Human Monocyte-Derived Dendritic Cells by Activated PlateletsQ28166057
Genetic and pharmacological analysis of prostanoid receptor functionQ28186062
Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregatesQ28213662
Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular eventsQ28238975
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic bloodQ28294906
Circulating mitochondrial DAMPs cause inflammatory responses to injuryQ29614470
Netting neutrophils in autoimmune small-vessel vasculitisQ29615432
Novel cell death program leads to neutrophil extracellular trapsQ29615433
Taking dendritic cells into medicineQ29619243
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.Q30090176
Staphylococcus aureus α-toxin triggers the synthesis of B-cell lymphoma 3 by human plateletsQ30318276
Inflammation induces hemorrhage in thrombocytopeniaQ30481913
Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteinsQ30487560
Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivoQ30591548
Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesisQ30663963
Platelet chemokines and their receptors: what is their relevance to platelet storage and transfusion practice?Q33341106
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed plateletsQ33342580
Role of blood platelets in infection and inflammationQ33344923
Platelets express functional Toll-like receptor-4.Q33366814
Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivoQ33368585
The biogenesis of platelets from megakaryocyte proplateletsQ33369405
Direct contact of platelets and their released products exert different effects on human dendritic cell maturation.Q33371979
Detection of hepatitis C virus in platelets: evaluating its relationship to viral and host factorsQ33375673
Thrombocytopenia in patients with dengue virus infection in the Brazilian AmazonQ33377566
Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.Q33378211
Imaging the interaction between dengue 2 virus and human blood platelets using atomic force and electron microscopyQ33379546
The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bendQ33381441
Platelets and HIV-1 infection: old and new aspectsQ33381510
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathwayQ33384817
Platelet functions beyond hemostasisQ33385887
The role of platelets in the pathogenesis of cerebral malariaQ33387926
Reduced thrombin generation increases host susceptibility to group A streptococcal infectionQ37086949
Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity.Q37126477
Platelet receptors and signaling in the dynamics of thrombus formation.Q37175605
TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humansQ37209180
Tissue factor storage, synthesis and function in normal and activated human plateletsQ37240160
Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.Q37241418
Amicus or adversary: platelets in lung biology, acute injury, and inflammationQ37250787
Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates.Q37262438
Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseasesQ37307308
G-protein-coupled receptors as signaling targets for antiplatelet therapyQ37331201
Activated platelets signal chemokine synthesis by human monocytesQ37353355
Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factorQ37373855
NETs: a new strategy for using old weaponsQ37584656
PSGL-1-dependent myeloid leukocyte activationQ37585925
Platelets and innate immunityQ37657202
Lymphangiogenesis: Molecular mechanisms and future promiseQ37697245
Intracellular toll-like receptorsQ37719951
The role of platelets in liver inflammation and regenerationQ37736338
Platelet Toll-like receptor expression: the link between "danger" ligands and inflammationQ37762278
Clinical relevance of microparticles from platelets and megakaryocytesQ37782534
Nuclear Emancipation: A Platelet Tour de ForceQ37801508
Platelets as initiators and mediators of inflammation at the vessel wallQ37811425
Platelets: versatile modifiers of innate and adaptive immune responses to transplantsQ37820880
Expression of Toll-like receptors on human plateletsQ37866864
P-selectin mediates Ca(2+)-dependent adhesion of activated platelets to many different types of leukocytes: detection by flow cytometryQ38327910
Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released productsQ38356959
Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins.Q39550459
Platelet microparticles are heterogeneous and highly dependent on the activation mechanism: studies using a new digital flow cytometerQ39781488
Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endotheliumQ40423150
Increased levels of soluble CD40L in African tick bite fever: possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets.Q40473187
HCV infective virions can be carried by human plateletsQ40512162
Cutting edge: T cells trigger CD40-dependent platelet activation and granular RANTES release: a novel pathway for immune response amplificationQ40592192
Platelet tissue factor synthesis in type 2 diabetic patients is resistant to inhibition by insulinQ40693554
Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.Q40785504
Role of platelet P-selectin and CD40 ligand in the induction of monocytic tissue factor expressionQ40849254
Interaction of endotoxic lipid A and lipid X with purified human platelet protein kinase C.Q41222565
Platelets and inflammationQ41550155
The interaction of leukocytes with platelets in blood coagulation.Q41644555
Activated platelets express IL-1 activityQ41758080
Platelet-derived interleukin 1 induces human endothelial adhesion molecule expression and cytokine productionQ41851230
CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophagesQ41859211
Effects of bacterial endotoxin on rabbit platelets. I. Platelet aggregation and release of platelet factors in vitroQ41995143
Platelets control leukocyte recruitment in a murine model of cutaneous arthus reactionQ42045612
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinaseQ42137745
Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migrationQ33390220
Complement activation on platelets: implications for vascular inflammation and thrombosisQ33390662
Plasmodium falciparum growth inhibition by human platelets in vitroQ33430310
Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and alpha-granule releaseQ33477430
Platelet factor 4 regulation of monocyte KLF4 in experimental cerebral malariaQ33573493
Class prediction models of thrombocytosis using genetic biomarkersQ33579530
Platelets in defense against bacterial pathogensQ33604443
Immunoregulatory functions of mTOR inhibition.Q33761278
Triggers, targets and treatments for thrombosisQ33765444
Neutrophils alter the inflammatory milieu by signal-dependent translation of constitutive messenger RNAs.Q33782606
Anucleate platelets generate progenyQ33834761
Glycoprotein IV mediates thrombospondin-dependent platelet-monocyte and platelet-U937 cell adhesionQ33848191
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenzaQ33875118
Platelet-activating factor and related lipid mediatorsQ33916020
The platelet as an immune cell-CD40 ligand and transfusion immunomodulationQ33937074
Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytesQ33943133
ETosis: a novel cell death pathwayQ34011929
Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart studyQ34023032
Existence of a microRNA pathway in anucleate plateletsQ34025954
Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic miceQ34052621
Immunodeficiency diseases caused by defects in phagocytesQ34098928
Cell-cell interactions: leukocyte-endothelial interactionsQ34176494
A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2Q34185817
Ligand bridging mediates integrin alpha IIb beta 3 (platelet GPIIB-IIIA) dependent homotypic and heterotypic cell-cell interactionsQ34203181
Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocationQ34218574
Platelets: signaling cells in the immune continuum.Q34342687
Platelet-mediated lymphocyte delivery to high endothelial venulesQ34384171
Platelets, leukocytes, and coagulation.Q34403977
Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate plateletsQ34442383
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.Q34452496
Protein synthesis by platelets: historical and new perspectivesQ34522274
Platelets as immune mediators: Their role in host defense responses and sepsisQ34590168
Regulation of adaptive immunity by the innate immune systemQ34659642
Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseasesQ34704835
Platelet binding to monocytes increases the adhesive properties of monocytes by up-regulating the expression and functionality of beta1 and beta2 integrinsQ46895647
Human marrow megakaryocyte differentiation: multiparameter correlative analysis identifies von Willebrand factor as a sensitive and distinctive marker for early (2N and 4N) megakaryocytes.Q47338623
Platelets deliver costimulatory signals to antigen-presenting cells: a potential bridge between injury and immune activationQ47720759
Platelets, after exposure to a high shear stress, induce IL-10-producing, mature dendritic cells in vitroQ47725989
Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartmentsQ47749276
Effect of glycoprotein IIb/IIIa antagonist abciximab on monocyte-platelet aggregates and tissue factor expressionQ47752199
Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9.Q47926367
Platelet secretory activities in acute malaria (Plasmodium falciparum) infectionQ47974174
Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarctionQ49031698
Effect of antiplatelet therapy on inflammatory markers in atherothrombotic patients.Q50276497
Platelets recruit human dendritic cells via Mac-1/JAM-C interaction and modulate dendritic cell function in vitro.Q50335763
Fibronectin bridges monocytes and reticulocytes via integrin alpha4beta1.Q50652273
Induction of platelet white blood cell (WBC) aggregate formation by platelets and WBCs in red blood cell units.Q50654530
The unexpected pleiotropic activities of RANTES.Q51758914
Molecular regulation of platelet-dependent thrombosis.Q52566814
Platelet factor 4 (CXCL4) seals blood clots by altering the structure of fibrin.Q53589389
Host defense role of platelets: engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation.Q53873685
Immunocytochemical localization of the chemokines RANTES and MIP-1 alpha within human platelets and their release during storage.Q54005107
Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease.Q54424737
Paracrine up-regulation of monocyte cyclooxygenase-2 by platelets: role of transforming growth factor-beta1.Q54560582
Tissue Factor in Patients With Acute Coronary SyndromesQ57398785
Dynamic Visualization of Thrombopoiesis Within Bone MarrowQ58450371
Increased platelet Fc receptor expression as a potential contributing cause of platelet hypersensitivity to collagen in diabetes mellitusQ60547969
Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human plateletsQ60687230
Platelet-lymphocyte conjugation differs between lymphocyte subpopulationsQ61684198
Prostaglandin E2 Differentially Modulates Human Platelet Function through the Prostanoid EP2 and EP3 ReceptorsQ61819363
Dynamics of leukocyte-platelet adhesion in whole bloodQ67700736
Effects of platelet activating factor (PAF) on human citrated whole bloodQ68466320
A platelet-derived immunoregulatory serum factor with T cell affinityQ69859051
Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated eventQ70708293
Neutrophil but not monocyte activation inhibits P-selectin-mediated platelet adhesionQ71683109
The presence of messenger RNA for HLA class I in human platelets and its capability for protein biosynthesisQ72550696
Specific accumulation of circulating monocytes and polymorphonuclear leukocytes on platelet thrombi in a vascular injury modelQ73063928
Human platelets can initiate T cell-dependent contact sensitivity through local serotonin release mediated by IgE antibodiesQ73128678
Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesisQ73224126
Induction of cytokine expression in leukocytes by binding of thrombin-stimulated plateletsQ73384671
Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophilsQ73836247
Platelet-derived interleukin-1 induces cytokine production, but not proliferation of human vascular smooth muscle cellsQ73981911
Down-regulation of monocyte apoptosis by phagocytosis of platelets: involvement of a caspase-9, caspase-3, and heat shock protein 70-dependent pathwayQ74261386
A juxtacrine mechanism for neutrophil adhesion on platelets involves platelet-activating factor and a selectin-dependent activation processQ74412931
Platelets induce monocyte differentiation in serum-free cocultureQ74449157
Differential regulation of matrix metalloproteinase-9 by monocytes adherent to collagen and plateletsQ74515086
Neutrophil enhancement of fibrin deposition under flow through platelet-dependent and -independent mechanismsQ77350608
A growing set of platelet-activating bacterial proteinsQ77468013
Platelet-monocyte aggregates: bridging thrombosis and inflammationQ78057253
Exogenous eosinophil activation converts PSGL-1-dependent binding to CD18-dependent stable adhesion to platelets in shear flowQ78799010
The septic milieu triggers expression of spliced tissue factor mRNA in human platelets.Q34765561
Mechanisms of thrombus formationQ34815800
Intravascular immunity: the host-pathogen encounter in blood vessels.Q34977555
Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signalingQ35039893
PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytesQ35160019
The evolving role of platelets in inflammation.Q35206747
mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.Q35642870
Safety and antithrombotic efficacy of moderate platelet count reduction by thrombopoietin inhibition in primatesQ35728878
Targeting IL-1 in inflammatory disease: new opportunities for therapeutic interventionQ35732863
P-selectin induces the expression of tissue factor on monocytesQ35746146
Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfacesQ35750125
Src family kinases mediate neutrophil adhesion to adherent plateletsQ35750833
Lipopolysaccharide is a direct agonist for platelet RNA splicingQ42248441
Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets.Q42582678
Immunology. Arsonists in rheumatoid arthritisQ42786605
Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosusQ42920089
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases.Q42950062
Hepatitis C virus interacts with human platelet glycoprotein VI.Q43001334
The dynamics of hepatitis C virus binding to platelets and 2 mononuclear cell linesQ43034754
Platelet-leukocyte cross talk in whole bloodQ43511991
Platelet derived CD154 (CD40 ligand) and febrile responses to transfusionQ43662394
Human platelets express heat shock protein receptors and regulate dendritic cell maturationQ43977703
LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement systemQ44182927
P-selectin enhances generation of CD14+CD16+ dendritic-like cells and inhibits macrophage maturation from human peripheral blood monocytesQ44504185
Transcriptional down-regulation of the platelet ADP receptor P2Y(12) and clusterin in patients with systemic lupus erythematosusQ45013467
Aggravation of viral hepatitis by platelet-derived serotoninQ45218233
Rolling of Th1 cells via P-selectin glycoprotein ligand-1 stimulates LFA-1-mediated cell binding to ICAM-1.Q45232002
Preferential binding of platelets to monocytes over neutrophils under flowQ45274360
Interaction of influenza virus with blood plateletsQ45809273
The blood platelets contribution to innate host defense - what they have learned from their big brothers.Q45977268
Platelets kill intraerythrocytic malarial parasites and mediate survival to infectionQ46131528
Leishmania immune adherence reaction in vertebratesQ46443728
The influence of platelet activating factor on the effects of platelet agonists and antiplatelet agents in vitroQ46522633
Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activityQ46767671
Anti-inflammatory effects of clopidogrel intake in renal transplant patients: effects on platelet-leukocyte interactions, platelet CD40 ligand expression, and proinflammatory biomarkersQ46830648
P433issue1
P304page(s)5-30
P577publication date2011-08-06
P1433published inSeminars in ImmunopathologyQ15724576
P1476titlePlatelets: versatile effector cells in hemostasis, inflammation, and the immune continuum
P478volume34

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cites work (P2860)
Q90494935A Journey Upstream: Fluctuating Platelet-Specific Genes in Cell Free Plasma as Proof-of-Concept for Using RNA Sequencing to Improve Understanding of Post-Injury Platelet Biology
Q46599341A Mathematical Model of Venous Thrombosis Initiation
Q41141811A Role for CD154, the CD40 Ligand, in Granulomatous Inflammation.
Q26753030Aberrant coagulation causes a hyper-inflammatory response in severe influenza pneumonia
Q36395085Alloantibody induced platelet responses in transplants: potent mediators in small packages
Q37526189Alteration of platelet GPVI signaling in ST-elevation myocardial infarction patients demonstrated by a combination of proteomic, biochemical, and functional approaches.
Q52350643Amicus or Adversary Revisited: Platelets in Acute Lung Injury & Acute Respiratory Distress Syndrome.
Q60303692An increase in mean platelet volume during admission can predict the prognoses of patients with pneumonia in the intensive care unit: A retrospective study
Q34398341Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice
Q47096645Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?
Q99634988Brucella abortus-Stimulated Platelets Activate Brain Microvascular Endothelial Cells Increasing Cell Transmigration through the Erk1/2 Pathway
Q27016554Cardiovascular disease in lupus: insights and updates
Q35733597Chemokine MCP1/CCL2 gene polymorphism influences Henoch-Schönlein purpura susceptibility in Iranian Azeri-Turkish patients
Q92471405Clinical Utility of Platelet Count as a Prognostic Marker for Melioidosis
Q40109059Clinical features of different clinical forms of childhood congenital hepatic fibrosis
Q58367220Dengue Virus Induces the Release of sCD40L and Changes in Levels of Membranal CD42b and CD40L Molecules in Human Platelets
Q58450774Desialylation of Platelets by Pneumococcal Neuraminidase A Induces ADP-Dependent Platelet Hyperreactivity
Q64117962Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue
Q41885031Dielectrophoresis-Mediated Electrodeformation as a Means of Determining Individual Platelet Stiffness.
Q37149704Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.
Q64986176Early Blood Biomarkers to Improve Sepsis/Bacteremia Diagnostics in Pediatric Emergency Settings.
Q88755027Early Intravascular Events Are Associated with Development of Acute Respiratory Distress Syndrome. A Substudy of the LIPS-A Clinical Trial
Q36625986Effector CD8 T cell trafficking within the liver
Q37696861Effects of pulmonary static inflation with 50% xenon on oxygen impairment during cardiopulmonary bypass for stanford type A acute aortic dissection: A pilot study
Q38310270Emerging evidence for platelets as immune and inflammatory effector cells
Q53168060Endometriosis-Derived Stromal Cells Secrete Thrombin and Thromboxane A2, Inducing Platelet Activation.
Q64928106Factors Associated with Low Admission Platelet Count in Adults with Acute Aortic Dissection.
Q52680357From blood coagulation to innate and adaptive immunity: the role of platelets in the physiology and pathology of autoimmune disorders.
Q38963810Global proteome analysis identifies active immunoproteasome subunits in human platelets
Q36009103In vivo platelet activation in critically ill patients with primary 2009 influenza A(H1N1)
Q33440172Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis
Q27692706Inflammasome in platelets: allying coagulation and inflammation in infectious and sterile diseases?
Q37195332Influence of mental stress on platelet bioactivity
Q36472299Influence of pre-existing inflammation on the outcome of acute coronary syndrome: a cross-sectional study
Q34557811Integrin αDβ2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling
Q28078773Intercellular Interactions as Regulators of NETosis
Q33424731Interferon-β therapy and risk of thrombocytopenia in multiple sclerosis patients
Q33425053Intramedullary megakaryocytes internalize released platelet factor 4 and store it in alpha granules
Q100944049Is there a relationship between morphological and functional platelet changes and depressive disorder?
Q36588205Lessons from rare maladies: leukocyte adhesion deficiency syndromes
Q38163600Live imaging of the lung
Q37395688Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation.
Q43182095New frontiers for platelet CD154.
Q38419319New horizons in platelet research: understanding and harnessing platelet functional diversity.
Q63916614Ontogeny of platelet function
Q27013790PAMPs and DAMPs as triggers for DIC
Q89338778PI3K/AKT and CD40L Signaling Regulate Platelet Activation and Endothelial Cell Damage in Sepsis
Q57292398Persistent platelet activation and apoptosis in virologically suppressed HIV-infected individuals
Q94592763Platelet Indices as the Predictor of Antibiotics Response in Surgical Wound Infections Following Total Abdominal Hysterectomy
Q33416386Platelet activation and apoptosis modulate monocyte inflammatory responses in dengue
Q64062919Platelet function in HIV plus dengue coinfection associates with reduced inflammation and milder dengue illness
Q33425031Platelet participation in the pathogenesis of dermonecrosis induced by Loxosceles gaucho venom
Q30250939Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue
Q38362628Platelet transfusion - the new immunology of an old therapy
Q36974692Platelet-Monocyte Aggregates and C-Reactive Protein are Associated with VTE in Older Surgical Patients
Q93342943Platelet-Neutrophil Interactions Are Lower in Cord Blood of Premature Newborns
Q38003425Platelet-associated angiogenesis regulating factors: a pharmacological perspective
Q34997292Platelet-derived stromal cell-derived factor-1 is required for the transformation of circulating monocytes into multipotential cells
Q47144868Platelets and Multi-Organ Failure in Sepsis
Q36058568Platelets and platelet-like particles mediate intercellular RNA transfer
Q37081746Platelets as cellular effectors of inflammation in vascular diseases
Q55004062Platelets in Immune Response to Virus and Immunopathology of Viral Infections.
Q26739670Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases
Q92106724Platelets in Skin Autoimmune Diseases
Q39027765Platelets in infectious disease.
Q38249957Platelets in inflammation and immunity
Q36897267Platelets in lung biology.
Q33410191Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation
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