Platelets as immune mediators: Their role in host defense responses and sepsis

scientific article published on November 13, 2010

Platelets as immune mediators: Their role in host defense responses and sepsis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.THROMRES.2010.10.010
P953full work available at URLhttps://europepmc.org/articles/pmc3042496?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21075430/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21075430/pdf/?tool=EBI
https://europepmc.org/articles/PMC3042496
https://europepmc.org/articles/PMC3042496?pdf=render
https://api.elsevier.com/content/article/PII:S0049384810005621?httpAccept=text/xml
https://doi.org/10.1016/j.thromres.2010.10.010
https://api.elsevier.com/content/article/PII:S0049384810005621?httpAccept=text/plain
P932PMC publication ID3042496
P698PubMed publication ID21075430
P5875ResearchGate publication ID47790861

P2093author name stringZhenyu Li
Fanmuyi Yang
Steve Dunn
Susan S. Smyth
A. Kendall Gross
P2860cites workLipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndromeQ24306498
Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic diseaseQ28218124
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic bloodQ28294906
The role of platelets in acute lung injury (ALI)Q30437474
Human platelets can activate peripheral blood B cells and increase production of immunoglobulins.Q33291901
Thrombocytopenia in a surgical ICU.Q33328833
Platelets express functional Toll-like receptor-4.Q33366814
Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivoQ33368585
Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU staysQ33375129
Platelets, petechiae, and preservation of the vascular wallQ33381203
Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathwayQ33384817
Platelet functions beyond hemostasisQ33385887
7E3 F(ab')2, a monoclonal antibody to the platelet GPIIb/IIIa receptor, protects against microangiopathic hemolytic anemia and microvascular thrombotic renal failure in baboons treated with C4b binding protein and a sublethal infusion of EscherichiaQ33499386
The platelet proteomeQ33904184
Roles for fibrinogen, immunoglobulin and complement in platelet activation promoted by Staphylococcus aureus clumping factor A.Q33988923
Prehospitalization antiplatelet therapy is associated with a reduced incidence of acute lung injury: a population-based cohort studyQ34545611
The interaction of bacterial pathogens with plateletsQ36482515
Platelet activation and atherothrombosisQ37031278
Platelets, neutrophils, and neutrophil extracellular traps (NETs) in sepsisQ37035362
Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseasesQ37307308
The CD40/CD40 ligand system: linking inflammation with atherothrombosisQ37579360
Anti-platelet drugs and outcome in severe infection: clinical impact and underlying mechanismsQ39890408
Antiplatelet drugs and outcome in mixed admissions to an intensive care unit.Q43273337
LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement systemQ44182927
Beneficial effect of clopidogrel in a mouse model of polymicrobial sepsis.Q45956998
Aspirin plus clopidogrel and risk of infection after coronary artery bypass surgery.Q46034373
Platelets kill intraerythrocytic malarial parasites and mediate survival to infectionQ46131528
Early endotoxin-mediated haemostatic and inflammatory responses in the clopidogrel-treated pig.Q46763608
Giulio Bizzozero: a pioneer of cell biology.Q48765547
Host defense role of platelets: engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation.Q53873685
Clopidogrel increases expression of chemokines in peripheral blood mononuclear cells in patients with coronary artery disease: results of a double-blind placebo-controlled study.Q54591387
Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent plateletsQ59065667
Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factorQ61669017
Thrombocytopenia in the intensive care unitQ70491550
Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endothelium in Escherichia coli endotoxin-induced shockQ73981728
Lipopolysaccharide induces sCD40L release through human platelets TLR4, but not TLR2 and TLR9Q79443070
In vivo effects of lipopolysaccharide and TLR4 on platelet production and activity: implications for thrombotic riskQ80134207
Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human plateletsQ80716085
Clopidogrel inhibits platelet-leukocyte adhesion and platelet-dependent leukocyte activationQ81438721
Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factorQ81443659
7E3 F(ab′)2 , a Monoclonal Antibody to the Platelet GPIIb/IIIa Receptor, Protects Against Microangiopathic Hemolytic Anemia and Microvascular Thrombotic Renal Failure in Baboons Treated With C4b Binding Protein and a Sublethal Infusion of EscherichiQ115668316
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectsepsisQ183134
P304page(s)184-188
P577publication date2010-11-13
P1433published inThrombosis ResearchQ15758741
P1476titlePlatelets as immune mediators: their role in host defense responses and sepsis
Platelets as immune mediators: Their role in host defense responses and sepsis
P478volume127