Platelets, petechiae, and preservation of the vascular wall

scientific article

Platelets, petechiae, and preservation of the vascular wall is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1056/NEJMRA0800887
P932PMC publication ID2935201
P698PubMed publication ID18799560
P5875ResearchGate publication ID23265922

P2093author name stringShahin Rafii
Ralph L Nachman
P2860cites workVEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signalingQ22009049
Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cellsQ24291455
Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinityQ24295448
Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartmentsQ24299236
The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-cateninQ27631714
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesisQ28140788
The functional role of blood platelet components in angiogenesisQ28209386
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumabQ28219257
The three-dimensional organization of tight junctions in a capillary endothelium revealed by serial-section electron microscopyQ28270187
IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coliQ28285153
Abnormal blood vessel development and lethality in embryos lacking a single VEGF alleleQ29547733
Angiogenesis: an organizing principle for drug discovery?Q29614538
Endothelial/pericyte interactionsQ29619802
Platelet-activating factor (PAF) induces corneal neovascularization and upregulates VEGF expression in endothelial cellsQ33206200
Intracranial hemorrhage in immune thrombocytopenic purpura: a retrospective analysisQ33349359
Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesisQ33358404
Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinibQ46735182
Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancerQ46892024
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
Vascular endothelial growth factor, epidermal growth factor and fibroblast growth factor-4 and -10 stimulate trophoblast plasminogen activator system and metalloproteinase-9.Q48008908
Platelets recruit human dendritic cells via Mac-1/JAM-C interaction and modulate dendritic cell function in vitroQ50335763
Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment.Q54579913
VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissuesQ57382249
Dynamic Visualization of Thrombopoiesis Within Bone MarrowQ58450371
Bcl-2 Orchestrates a Cross-talk between Endothelial and Tumor Cells that Promotes Tumor GrowthQ62336484
Unidirectional crosstalk between Bcl-xL and Bcl-2 enhances the angiogenic phenotype of endothelial cellsQ62336491
Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitorsQ71789644
Positive and negative hematopoietic cytokines produced by bone marrow endothelial cellsQ73954015
Expression of thrombopoietin by umbilical vein endothelial cellsQ74000323
Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cellsQ77850439
Fluid shear stress enhances the sphingosine 1-phosphate responses in cell-cell interactions between platelets and endothelial cellsQ80356980
Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytesQ33371036
Programmed anuclear cell death delimits platelet life span.Q33374664
The anatomic basis of purpuraQ33483458
Amelioration of endothelial abnormalities by prednisone in experimental thrombocytopenia in the rabbitQ33498850
Current biology of VEGF-B and VEGF-C.Q33796264
VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cellsQ34035717
The molecular organization of endothelial junctions and their functional role in vascular morphogenesis and permeability.Q34075670
Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivationQ34380698
Autocrine VEGF signaling is required for vascular homeostasisQ34443661
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.Q34455428
Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially releasedQ34584213
Platelets in atherothrombosisQ34986345
The role of neuropilin in vascular and tumor biology.Q35076249
Radiation and ceramide-induced apoptosisQ35208833
Endothelial cell-cell junctions: happy togetherQ35741007
Platelets accumulate in the diabetic retinal vasculature following endothelial death and suppress blood-retinal barrier breakdownQ35791582
Angiogenic imbalance in the pathophysiology of preeclampsia: newer insightsQ35941009
Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and plateletsQ35960196
The biology of vascular endothelial growth factors.Q36017169
The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-cateninQ36229078
Pericytes and vascular stabilityQ36319680
Lessons from phase III clinical trials on anti-VEGF therapy for cancerQ36366446
Discovery of vascular permeability factor (VPF).Q36375479
The multiple languages of endothelial cell-to-cell communicationQ36429966
Phospho-regulation of Beta-catenin adhesion and signaling functions.Q36967628
Platelet activation and atherothrombosisQ37031278
Platelets modulate atherogenesis and progression of atherosclerotic plaques via interaction with progenitor and dendritic cells.Q37035357
Synthesis of Factor VIII Antigen by Cultured Guinea Pig MegakaryocytesQ37047673
Synthesis of von Willebrand factor by cultured human endothelial cellsQ37444356
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signalingQ40751632
The molecular organization of tight junctionsQ40903764
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cellsQ41144930
Interendothelial junctions: structure, signalling and functional roles.Q41612546
The mechanism of vascular leakage induced by leukotriene E4. Endothelial contractionQ41881567
The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesisQ42411644
Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogensQ42805681
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanismQ44043571
Osteopontin expression and adventitial angiogenesis induced by local vascular endothelial growth factor 165 reduces experimental aortic calcificationQ46283969
Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actininQ46728817
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectpetechiaQ1412657
P304page(s)1261-1270
P577publication date2008-09-01
P1433published inThe New England Journal of MedicineQ582728
P1476titlePlatelets, petechiae, and preservation of the vascular wall
P478volume359

Reverse relations

cites work (P2860)
Q4812634024-h continuous infusion of platelets for patients with platelet transfusion refractoriness
Q90494935A Journey Upstream: Fluctuating Platelet-Specific Genes in Cell Free Plasma as Proof-of-Concept for Using RNA Sequencing to Improve Understanding of Post-Injury Platelet Biology
Q37432574A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects
Q33429565A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial
Q33407813Alternate considerations for current concepts in ITP.
Q52350643Amicus or Adversary Revisited: Platelets in Acute Lung Injury & Acute Respiratory Distress Syndrome.
Q37688711Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target?
Q37047000Bacillus anthracis peptidoglycan activates human platelets through FcγRII and complement
Q34593475Bevacizumab combined with chemotherapy for advanced non-small cell lung cancer: a meta-analysis
Q30525402Bleeding risks are higher in children versus adults given prophylactic platelet transfusions for treatment-induced hypoproliferative thrombocytopenia
Q33424357Blocking neutrophil diapedesis prevents hemorrhage during thrombocytopenia
Q47096645Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critical ill patients?
Q34805344Brain haemosiderin in older people: pathological evidence for an ischaemic origin of magnetic resonance imaging (MRI) microbleeds
Q38148437Brain regulation of thrombosis and hemostasis: from theory to practice
Q95321982COVID-19: the vasculature unleashed
Q33807542Cardio-Oncology: Cancer Therapy-related Cardiovascular Complications in a Molecular Targeted Era: New Concepts and Perspectives
Q36721511Cardiovascular Toxicity of Molecular Targeted Therapy in Cancer Patients: A Double-Edged Sword
Q33396038Cardiovascular interventions in thrombocytopenic cancer patients
Q53276936Cardiovascular toxic effects of targeted cancer therapy.
Q34813136Cerebral microbleeds in the elderly: a pathological analysis
Q35599819Clinical development of VEGF signaling pathway inhibitors in childhood solid tumors.
Q83395977Comment on: Dengue mortality: reassessing the risks in transition countries
Q38286128Conquests and perspectives of cardio-oncology in the field of tumor angiogenesis-targeting tyrosine kinase inhibitor-based therapy
Q37831798Contribution of platelets to tumour metastasis.
Q24645380Dengue virus pathogenesis: an integrated view
Q64117962Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue
Q24198832Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation
Q24186359Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation
Q83026961Differential changes in platelet VEGF, Tsp, CXCL12, and CXCL4 in patients with metastatic cancer
Q30494712Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis
Q54970116Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour.
Q38284439Early treatment with rutoside and ascorbic acid is highly effective for progressive pigmented purpuric dermatosis
Q36122760Efficacy of platelet-rich plasma in the treatment of androgenetic (male-patterned) alopecia: A pilot randomized controlled trial.
Q44877409Endothelial alterations in a canine model of immune thrombocytopenia.
Q58571918Endothelial-Vascular Smooth Muscle Cells Interactions in Atherosclerosis
Q35694069Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis
Q34674369Expression of regulatory platelet microRNAs in patients with sickle cell disease
Q38341556Gene expression profiling in peripheral blood nuclear cells in patients with refractory ischaemic end-stage heart failure.
Q30240053How do we approach thrombocytopenia in critically ill patients?
Q35588157How platelets safeguard vascular integrity
Q26997803Human platelets and their capacity of binding viruses: meaning and challenges?
Q33403135Imbalance of angiopoietin-1 and angiopoetin-2 in severe dengue and relationship with thrombocytopenia, endothelial activation, and vascular stability
Q27342617Impaired integrin β3 delays endothelial cell regeneration and contributes to arteriovenous graft failure in mice
Q53317633In vitro evaluation of the hemostatic effectiveness of cryopreserved platelets.
Q33386103Innate immune cells induce hemorrhage in tumors during thrombocytopenia
Q33413225Intracranial haemorrhage in thrombocytopenic haematology patients--a nested case-control study: the InCiTe study protocol
Q84791878Intravitreous VEGF-A in eyes with massive vitreous hemorrhage
Q33437777Management of severe dengue hemorrhagic fever and bleeding complications in a primigravida patient: a case report
Q26862087Megakaryocytes, malignancy and bone marrow vascular niches
Q38495085Nanodiagnostics, nanopharmacology and nanotoxicology of platelet-vessel wall interactions.
Q38749029Paper-based point-of-care testing for diagnosis of dengue infections
Q33753094Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis
Q89471812Perhaps it's not the platelet: Ristocetin uncovers the potential role of von Willebrand factor in impaired platelet aggregation following traumatic brain injury
Q34765904Platelet activation determines angiopoietin-1 and VEGF levels in malaria: implications for their use as biomarkers
Q37932076Platelet activation in obesity and metabolic syndrome
Q38281989Platelet secretion: From haemostasis to wound healing and beyond
Q37982455Platelet signaling-a primer.
Q33395509Platelet transfusions for patients with haematological malignancies: who needs them?
Q35829738Platelet-rich plasma peptides: key for regeneration
Q90403621Platelets Are at the Nexus of Vascular Diseases
Q33440142Platelets and infections in the resource-limited countries with a focus on malaria and viral haemorrhagic fevers
Q34590168Platelets as immune mediators: Their role in host defense responses and sepsis
Q55004062Platelets in Immune Response to Virus and Immunopathology of Viral Infections.
Q26739670Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases
Q26852677Platelets in inflammation: regulation of leukocyte activities and vascular repair
Q36897267Platelets in lung biology.
Q33404240Platelets in pulmonary vascular physiology and pathology
Q36070471Platelets induce apoptosis via membrane-bound FasL.
Q37398523Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets.
Q89950822Platelets, Micro-Particles and Elastase. A Review with Extrapolation to the Mechanism of Generation and Bio-Pathology of Platelet Fragments
Q84066488Platelets, oxidative stress and preservation of the vascular endothelium: is it a matter of fat?
Q39248498Platelets: much more than bricks in a breached wall.
Q92717119Prediction of Ticagrelor and its Active Metabolite in Liver Cirrhosis Populations Using a Physiologically Based Pharmacokinetic Model Involving Pharmacodynamics
Q64096001Prophylactic oral NAC reduced poor hematopoietic reconstitution by improving endothelial cells after haploidentical transplantation
Q24197779Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell transplantation
Q41863261Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw
Q42946822Ramping up RANTES in the acute response to arterial injury
Q36409037S1P and the birth of platelets.
Q38834645Smart blood cell and microvesicle-based Trojan horse drug delivery: Merging expertise in blood transfusion and biomedical engineering in the field of nanomedicine
Q90289537Spontaneous bleeding in thrombocytopenia: Is it really spontaneous?
Q46015443The effects of 22°C and 4°C storage of platelets on vascular endothelial integrity and function.
Q38212058The functional role of platelets in the regulation of angiogenesis
Q63407979The physiological and pathophysiological roles of platelet CLEC-2
Q92222177Transforming Endothelium with Platelet-Rich Plasma in Engineered Microvessels
Q50115928Translational Implications of Platelets as Vascular First Responders
Q35022509Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps
Q93082879Two-stage oxygen delivery for enhanced radiotherapy by perfluorocarbon nanoparticles
Q91596480Unexpected effects of long-term treatment with acetylsalicylic acid on late phase of pulmonary metastasis in murine model of orthotopic breast cancer
Q92257481Vascularized Microfluidics and the Blood-Endothelium Interface
Q90392500α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis

Search more.