| scholarly article | Q13442814 |
| P2093 | author name string | Xiaoping Du | |
| Asrar B Malik | |||
| Emily J Welch | |||
| Zhenyu Li | |||
| Jingyan Han | |||
| Guoying Zhang | |||
| Richard D Ye | |||
| Tatyana A Voyno-Yasenetskaya | |||
| P2860 | cites work | Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene | Q22299417 |
| Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome | Q24306498 | ||
| Structure and function of lipopolysaccharide binding protein | Q24324774 | ||
| A human homologue of the Drosophila Toll protein signals activation of adaptive immunity | Q28131769 | ||
| Lipopolysaccharides of Bacteroides fragilis, Chlamydia trachomatis and Pseudomonas aeruginosa signal via toll-like receptor 2 | Q28273574 | ||
| Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 | Q28283196 | ||
| Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood | Q28294906 | ||
| Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation | Q28588671 | ||
| CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein | Q29615189 | ||
| Platelet function in sepsis | Q33342364 | ||
| Platelets express functional Toll-like receptor-4. | Q33366814 | ||
| Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo | Q33368585 | ||
| Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets | Q33374234 | ||
| 7E3 F(ab')2, a monoclonal antibody to the platelet GPIIb/IIIa receptor, protects against microangiopathic hemolytic anemia and microvascular thrombotic renal failure in baboons treated with C4b binding protein and a sublethal infusion of Escherichia | Q33499386 | ||
| Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism. | Q33940165 | ||
| Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. | Q33993559 | ||
| Stimulatory roles of nitric-oxide synthase 3 and guanylyl cyclase in platelet activation | Q34448738 | ||
| TIR domain-containing adaptors define the specificity of TLR signaling | Q35617615 | ||
| TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase | Q36259614 | ||
| Aggregation behavior of an ultra-pure lipopolysaccharide that stimulates TLR-4 receptors | Q36737111 | ||
| Endotoxin concentration in neutropenic patients with suspected gram-negative sepsis: correlation with clinical outcome and determination of anti-endotoxin core antibodies during therapy with polyclonal immunoglobulin M-enriched immunoglobulins | Q36757740 | ||
| Nitric oxide released from activated platelets inhibits platelet recruitment | Q37369997 | ||
| Complement-dependent accumulation and degradation of platelets in the lung and liver induced by injection of lipopolysaccharides | Q39512262 | ||
| Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. | Q40014914 | ||
| Regulation of cementoblast function by P. gingivalis lipopolysaccharide via TLR2. | Q40252425 | ||
| Lipopolysaccharide is a direct agonist for platelet RNA splicing | Q42248441 | ||
| Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I. | Q42944020 | ||
| LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement system | Q44182927 | ||
| A stimulatory role for cGMP-dependent protein kinase in platelet activation | Q44277303 | ||
| Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases | Q44471598 | ||
| Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa). | Q44645544 | ||
| A platelet secretion pathway mediated by cGMP-dependent protein kinase | Q44997709 | ||
| A family of lipopolysaccharide binding proteins involved in responses to gram-negative sepsis. | Q46536693 | ||
| Effect of gram-negative bacterial lipopolysaccharide-derived polysaccharides, glycolipids, and lipopolysaccharides on rabbit and human platelets in vitro | Q46906693 | ||
| Effects of a variety of endotoxins on human and rabbit platelet function | Q47728751 | ||
| Contrasting effects of lipopolysaccharides (endotoxins) from oral black-pigmented bacteria and Enterobacteriaceae on platelets, a major source of serotonin, and on histamine-forming enzyme in mice | Q50134210 | ||
| Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole blood | Q58831626 | ||
| Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endothelium in Escherichia coli endotoxin-induced shock | Q73981728 | ||
| The antiplatelet activity of Escherichia coli lipopolysaccharide is mediated through a nitric oxide/cyclic GMP pathway | Q77844522 | ||
| Unresponsiveness of MyD88-deficient mice to endotoxin | Q78093558 | ||
| A predominant role for cAMP-dependent protein kinase in the cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans | Q78952570 | ||
| Immediate effects of intravenous endotoxin on serotonin concentrations and blood platelets | Q79207419 | ||
| Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets | Q80716085 | ||
| Compensatory mechanisms influence hemostasis in setting of eNOS deficiency | Q81056864 | ||
| Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor | Q81443659 | ||
| Endotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanism | Q81472583 | ||
| Evidence of Toll-like receptor molecules on human platelets | Q81479217 | ||
| A phosphoinositide 3-kinase-AKT-nitric oxide-cGMP signaling pathway in stimulating platelet secretion and aggregation | Q83153648 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | toll-like receptor | Q408004 |
| lipopolysaccharide | Q421804 | ||
| platelet aggregation | Q14913634 | ||
| P304 | page(s) | 7997-8004 | |
| P577 | publication date | 2009-06-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway | |
| P478 | volume | 182 |
| Q33629231 | A Randomized Placebo Controlled Trial of Aspirin Effects on Immune Activation in Chronically Human Immunodeficiency Virus-Infected Adults on Virologically Suppressive Antiretroviral Therapy. |
| Q38451947 | A review and discussion of platelet nitric oxide and nitric oxide synthase: do blood platelets produce nitric oxide from L-arginine or nitrite? |
| Q33399007 | ATP-gated P2X1 ion channels protect against endotoxemia by dampening neutrophil activation |
| Q33443707 | Acetylsalicylic acid differentially limits the activation and expression of cell death markers in human platelets exposed to Staphylococcus aureus strains |
| Q38112059 | Acute lung injury and pulmonary vascular permeability: use of transgenic models |
| Q33409741 | Amelioration of murine passive immune thrombocytopenia by IVIg and a therapeutic monoclonal CD44 antibody does not require the Myd88 signaling pathway |
| Q37353931 | Annexin A5 increases survival in murine sepsis model by inhibiting HMGB1-mediated pro-inflammation and coagulation. |
| Q38539151 | Antiplatelet antibody may cause delayed transfusion-related acute lung injury |
| Q44098585 | Ascorbate reduces mouse platelet aggregation and surface P-selectin expression in an ex vivo model of sepsis |
| Q38367560 | Bacterial Adaptation during Chronic Respiratory Infections. |
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| Q33401507 | Bidirectional crosstalk between platelets and monocytes initiated by Toll-like receptor: an important step in the early defense against fungal infections? |
| Q45059688 | Blood platelets and biological response to 'danger' signals and subsequent inflammation: towards a new paradigm? |
| Q34204639 | Calpain activity and Toll-like receptor 4 expression in platelet regulate haemostatic situation in patients undergoing cardiac surgery and coagulation in mice. |
| Q91895067 | Canine platelets express functional Toll-like receptor-4: lipopolysaccharide-triggered platelet activation is dependent on adenosine diphosphate and thromboxane A2 in dogs |
| Q37197516 | Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin |
| Q28081769 | Cardiotoxicity during invasive pneumococcal disease |
| Q61800023 | Cell Type-Specific Roles of NF-κB Linking Inflammation and Thrombosis |
| Q35607298 | Cellular fibronectin containing extra domain A promotes arterial thrombosis in mice through platelet Toll-like receptor 4 |
| Q48169544 | Chronic periodontitis is associated with platelet factor 4 (PF4) secretion: A pilot study |
| Q49953603 | Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis |
| Q30415074 | Clopidogrel treatment and the incidence and severity of community acquired pneumonia in a cohort study and meta-analysis of antiplatelet therapy in pneumonia and critical illness |
| Q37825577 | Critical role for oxidative stress, platelets, and coagulation in capillary blood flow impairment in sepsis |
| Q33403517 | Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries |
| Q43797072 | Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in L-NAME-induced hypertension. |
| Q56396121 | Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate |
| Q64099633 | Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage |
| Q39114910 | Do aspirin and other antiplatelet drugs reduce the mortality in critically ill patients? |
| Q28390993 | Down-regulation of platelet surface CD47 expression in Escherichia coli O157:H7 infection-induced thrombocytopenia |
| Q33885430 | Effect of dietary supplementation of procyanidin on growth performance and immune response in pigs |
| Q91657132 | Effect of ultrapure lipopolysaccharides derived from diverse bacterial species on the modulation of platelet activation |
| Q97681252 | Effects of bacterial lipopolysaccharides on platelet function: inhibition of weak platelet activation |
| Q44419623 | Efficient phagocytosis of periodontopathogens by neutrophils requires plasma factors, platelets and TLR2. |
| Q35921921 | Elevated Toll-Like Receptor-Induced CXCL8 Secretion in Human Blood Basophils from Allergic Donors Is Independent of Toll-Like Receptor Expression Levels |
| Q36510868 | Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis. |
| Q45832161 | Equine platelets inhibit E. coli growth and can be activated by bacterial lipopolysaccharide and lipoteichoic acid although superoxide anion production does not occur and platelet activation is not associated with enhanced production by neutrophils |
| Q33428410 | Escherichia coli induces platelet aggregation in an FcγRIIa-dependent manner |
| Q91374379 | Exogenous carbon monoxide suppresses LPS-Induced platelet SNAREs complex assembly and α-granule exocytosis via integrin αIIbβ3-Mediated PKCθ/Munc18a pathway |
| Q51704486 | Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets. |
| Q33419814 | Expression and functionality of Toll-like receptor 3 in the megakaryocytic lineage |
| Q35172492 | Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4 |
| Q64066788 | Generation of platelet-derived microparticles through the activation of the toll-like receptor 4 |
| Q33698036 | Genetic deletion of toll-like receptor 4 on platelets attenuates experimental pulmonary hypertension |
| Q41650213 | Human coagulation factor X-adenovirus type 5 complexes poorly stimulate an innate immune response in human mononuclear phagocytes |
| Q90401101 | Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation |
| Q33864069 | Inflammation and thrombosis in cardiovascular disease. |
| Q94587197 | Inflammatory signaling in dengue-infected platelets requires translation and secretion of nonstructural protein 1 |
| Q40896463 | Inhibition of COX-1 attenuates the formation of thromboxane A2 and ameliorates the acute decrease in glomerular filtration rate in endotoxemic mice. |
| Q36611493 | Inhibition of MCF-7 breast cancer cell-induced platelet aggregation using a combination of antiplatelet drugs |
| Q28078773 | Intercellular Interactions as Regulators of NETosis |
| Q35136658 | Kinase activity profiling of gram-negative pneumonia |
| Q35067863 | LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-Ligand. |
| Q34038374 | Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide |
| Q46261707 | Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA2 signalling |
| Q37281999 | Lipopolysaccharide stimulates platelets through an IL-1β autocrine loop |
| Q40536260 | Low-grade endotoxemia and platelet activation in cirrhosis |
| Q92543091 | Macrophage Depletion Mitigates Platelet Aggregate Formation in Splenic Marginal Zone and Alleviates LPS-Associated Thrombocytopenia in Rats |
| Q43135345 | Mechanisms underlying the inhibitory effects of lipopolysaccharide on human platelet adhesion |
| Q54249498 | Mediators and molecular pathways involved in the regulation of neutrophil extracellular trap formation mediated by activated platelets. |
| Q46245186 | Modification of immunological features in human platelets during sepsis. |
| Q37625592 | NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets |
| Q39147112 | New Concepts and Mechanisms of Platelet Activation Signaling |
| Q36248009 | Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability |
| Q35246390 | Nucleotide-binding oligomerization domain 2 receptor is expressed in platelets and enhances platelet activation and thrombosis |
| Q48302820 | Obesity and Altered Aspirin Pharmacology |
| Q37731752 | P2X7 receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction. |
| Q36849627 | P2Y12 Receptor Modulates Sepsis-Induced Inflammation |
| Q90049837 | Parkinson's Disease: A Systemic Inflammatory Disease Accompanied by Bacterial Inflammagens |
| Q89169483 | Platelet Signaling and Disease: Targeted Therapy for Thrombosis and Other Related Diseases |
| Q95271937 | Platelet Toll-Like Receptors Mediate Thromboinflammatory Responses in Patients With Essential Thrombocythemia |
| Q35213593 | Platelet activation attracts a subpopulation of effector monocytes to sites of Leishmania major infection |
| Q37422974 | Platelet function beyond hemostasis and thrombosis |
| Q36335907 | Platelet-derived HMGB1 is a critical mediator of thrombosis. |
| Q34387761 | Platelet-derived Toll-like receptor 4 (Tlr-4) is sufficient to promote microvascular thrombosis in endotoxemia. |
| Q47381141 | Platelets Toll-like receptor-4 in Crohns disease |
| Q38017397 | Platelets and cytokines: How and why? |
| Q35124418 | Platelets and infections - complex interactions with bacteria. |
| Q37657202 | Platelets and innate immunity |
| Q37857647 | Platelets and the immune continuum |
| Q33432917 | Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond |
| Q37081746 | Platelets as cellular effectors of inflammation in vascular diseases |
| Q34590168 | Platelets as immune mediators: Their role in host defense responses and sepsis |
| Q57676581 | Platelets as immune-sensing cells |
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| Q33411077 | Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway |
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