The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes

scientific article

The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.THROMRES.2009.11.004
P932PMC publication ID2830335
P698PubMed publication ID19945154
P5875ResearchGate publication ID40038291

P50authorJane E. FreedmanQ125127316
P2093author name stringLea M Beaulieu
P2860cites workLipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets through TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndromeQ24306498
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Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic bloodQ28294906
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Role of blood platelets in infection and inflammationQ33344923
Platelets express functional Toll-like receptor-4.Q33366814
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Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathwayQ33384817
Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and alpha-granule releaseQ33477430
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Chlamydia pneumoniae binds to platelets and triggers P-selectin expression and aggregation: a causal role in cardiovascular disease?Q37869092
Biphasic, organ-specific, and strain-specific accumulation of platelets induced in mice by a lipopolysaccharide from Escherichia coli and its possible involvement in shockQ39826933
Increased levels of soluble CD40L in African tick bite fever: possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets.Q40473187
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Platelet-leukocyte interaction and platelet activation in acute stroke with and without preceding infection.Q45066041
Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinaseQ46854879
Thrombocytes respond to lipopolysaccharide through Toll-like receptor-4, and MAP kinase and NF-kappaB pathways leading to expression of interleukin-6 and cyclooxygenase-2 with production of prostaglandin E2.Q50068774
Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole bloodQ58831626
Synthetic lipopeptide Pam3CysSer(Lys)4 is an effective activator of human plateletsQ60687230
Platelet activation by Protease I of Porphyromonas gingivalis W83Q70469219
Effects of endotoxemia on thrombopoiesis in menQ77425094
Mechanisms involved in the antiplatelet activity of Escherichia coli lipopolysaccharide in human plateletsQ77476698
Induction of platelet thrombi by bacteria and antibodiesQ78410425
Immediate effects of intravenous endotoxin on serotonin concentrations and blood plateletsQ79207419
Lipopolysaccharide induces sCD40L release through human platelets TLR4, but not TLR2 and TLR9Q79443070
Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromesQ79819381
In vivo effects of lipopolysaccharide and TLR4 on platelet production and activity: implications for thrombotic riskQ80134207
Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human plateletsQ80716085
Agonists of toll-like receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factorQ81443659
Endotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanismQ81472583
Evidence of Toll-like receptor molecules on human plateletsQ81479217
Toll-like receptors on platelets: the key for disseminated intravascular coagulation in sepsis?Q81579388
Blockade of glycoprotein IIb/IIIa by crotavirin, a member of disintegrins, prevents platelet from activation and aggregation by Staphylococcus aureus bacteriaQ81770492
P433issue3
P921main subjectinflammationQ101991
toll-like receptorQ408004
P304page(s)205-209
P577publication date2009-11-27
P1433published inThrombosis ResearchQ15758741
P1476titleThe role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes
P478volume125

Reverse relations

cites work (P2860)
Q28083403Are Platelets Cells? And if Yes, are They Immune Cells?
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Q48302820Obesity and Altered Aspirin Pharmacology
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Q35922965RETRACTED ARTICLE: HMGB1: a novel protein that induced platelets active and aggregation via Toll-like receptor-4, NF-κB and cGMP dependent mechanisms
Q89511537Reduced miR-26b Expression in Megakaryocytes and Platelets Contributes to Elevated Level of Platelet Activation Status in Sepsis
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