Structure and function of leukocyte chemoattractant receptors

scientific article published on January 1997

Structure and function of leukocyte chemoattractant receptors is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S1054-3589(08)60073-3
P698PubMed publication ID9160117

P2093author name stringBoulay F
Ye RD
P2860cites workHIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorQ22242268
Identification of a major co-receptor for primary isolates of HIV-1Q22251282
Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptorQ24292683
Differentiation-specific expression of a novel G protein-coupled receptor from Burkitt's lymphomaQ24294397
Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cellsQ24294938
Rhodopsin mutants that bind but fail to activate transducinQ24300261
Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heartQ24306153
Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tailsQ24310185
A Receptor for the Malarial Parasite Plasmodium vivax : the Erythrocyte Chemokine ReceptorQ24310519
Characterization of a human cDNA that encodes a functional receptor for platelet activating factorQ24311426
RANTES and MCP-3 antagonists bind multiple chemokine receptorsQ24311470
Molecular cloning and characterization of the human anaphylatoxin C3a receptorQ24311767
Monocyte chemoattractant protein-3 is a functional ligand for CC chemokine receptors 1 and 2BQ24312872
Molecular cloning and functional expression of a new human CC-chemokine receptor geneQ24313022
Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptorsQ24314660
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entryQ24315492
Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytesQ24316041
New members of the chemokine receptor gene familyQ24316524
Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cellsQ24317197
The C5a chemoattractant receptor mediates mucosal defence to infectionQ24318486
Structure and Functional Expression of a Human Interleukin-8 ReceptorQ24319897
Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alphaQ24321555
Molecular Cloning and Functional Expression of a Novel CC Chemokine Receptor cDNA from a Human Basophilic Cell LineQ24323381
Mitogen-activated Protein Kinase Activation Requires Two Signal Inputs from the Human Anaphylatoxin C5a ReceptorQ24324735
G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase CQ24324791
G Protein-coupled Chemoattractant Receptors Regulate Lyn Tyrosine Kinase·Shc Adapter Protein Signaling ComplexesQ24324803
Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytesQ24336187
The human platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1Q24336964
Sequence variation of a novel heptahelical leucocyte receptor through alternative transcript formationQ24528197
Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophilsQ24562774
High- and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophilsQ24563339
Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for the Plasmodium vivax malaria parasiteQ24564153
C5a-induced expression of P-selectin in endothelial cellsQ24633672
Ras-related GTPases and the cytoskeletonQ24658227
Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8Q24675647
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)Q24677007
Cloning, expression, and characterization of the human eosinophil eotaxin receptorQ24678271
Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factorQ24679152
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammationQ24680123
The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytesQ24680160
Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptorQ24680555
Crystal structure of interleukin 8: symbiosis of NMR and crystallographyQ27658056
Substituted 4,6-diaminoquinolines as inhibitors of C5a receptor bindingQ67485755
Signal transduction in neutrophil activation. Phosphatidylinositol 3-kinase is stimulated without tyrosine phosphorylationQ67503254
Neutrophil activating peptide-2 binds with two affinities to receptor(s) on human neutrophilsQ68028110
Multisite contacts involved in coupling of the beta-adrenergic receptor with the stimulatory guanine-nucleotide-binding regulatory protein. Structural and functional studies by beta-receptor-site-specific synthetic peptidesQ68238152
A model for the C5a receptor and for T its interaction with the ligandQ68275811
Synthesis of a new photoreactive C5a analog that permits identification of the ligand binding component of the granulocyte C5a receptorQ69464071
Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonistQ69833004
Characterization of monocyte chemotactic protein-1 binding to human monocytesQ70140841
Role of Rho in chemoattractant-activated leukocyte adhesion through integrinsQ70960218
Active site of C3a anaphylatoxin: contributions of the lipophilic and orienting residuesQ71005861
N-terminus urea-substituted chemotactic peptides: new potent agonists and antagonists toward the neutrophil fMLF receptorQ71176172
Signal transduction by the formyl peptide receptor. Studies using chimeric receptors and site-directed mutagenesis define a novel domain for interaction with G-proteinsQ71585712
Activation of dual T cell signaling pathways by the chemokine RANTESQ71768178
Peptides from the amino-terminus of mouse mitochondrially encoded NADH dehydrogenase subunit 1 are potent chemoattractantsQ71840056
Arginine 206 of the C5a Receptor Is Critical for Ligand Recognition and Receptor Activation by C-terminal Hexapeptide AnalogsQ71869189
Interleukin-8 receptor beta. The role of the carboxyl terminus in signal transductionQ72167747
Different alpha 1-adrenergic receptor sequences required for activating different G alpha subunits of Gq class of G proteinsQ72191113
Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophilsQ72223341
Dissociation of mitogen-activated protein kinase activation from the oxidative burst in differentiated HL-60 cells and human neutrophilsQ72350554
A carboxyl-terminal tail peptide of neutrophil chemotactic receptor disrupts its physical complex with G proteinQ72621164
Human C5a and C5a analogs as probes of the neutrophil C5a receptorQ72856944
Formyl peptide chemoattractants: a model of the receptor on rabbit neutrophilsQ72928745
HIV blocked by chemokine antagonistQ59084831
Projection structure of rhodopsinQ59098567
Extensive Contact between Gi2 and N-Formyl Peptide Receptor of Human Neutrophils: Mapping of Binding Sites Using Receptor-Mimetic PeptidesQ59942398
Preparation and properties of an improved photoaffinity ligand for the N-formyl peptide receptorQ59942408
Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factorsQ60673557
Three cytoplasmic loops of rhodopsin interact with transducinQ34302756
Phosphorylation of the N-formyl peptide receptor carboxyl terminus by the G protein-coupled receptor kinase, GRK2.Q34317288
Physical coupling of N-formyl peptide chemoattractant receptors to G protein is unaffected by desensitization.Q34324625
Characterization of complex formation between Gi2 and octyl glucoside solubilized neutrophil N-formyl peptide chemoattractant receptor by sedimentation velocity.Q34324776
The interleukin-8-receptor family: from chemokines to malariaQ34342254
Sequence and organization of the human N-formyl peptide receptor-encoding geneQ34343699
Binding and metabolism of platelet-activating factor by human neutrophilsQ34532662
Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological functionQ34629220
Neutrophil activation by monomeric interleukin-8.Q34662590
Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptorsQ35034275
Molecular cloning and structure of a pre-B-cell growth-stimulating factorQ35106000
In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptorsQ35227301
A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains.Q35868457
Lateral segregation of neutrophil chemotactic receptors into actin- and fodrin-rich plasma membrane microdomains depleted in guanyl nucleotide regulatory proteinsQ36219505
N-formyl peptide receptors in human neutrophils display distinct membrane distribution and lateral mobility when labeled with agonist and antagonistQ36232944
Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg.Q36251731
Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptorsQ36346853
Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokinesQ36361364
A high potency nonformylated peptide agonist for the phagocyte N-formylpeptide chemotactic receptorQ36364113
Model systems for the study of seven-transmembrane-segment receptorsQ36417986
A Dominant Negative Inhibitor Indicates that Monocyte Chemoattractant Protein 1 Functions as a DimerQ36554378
Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lungQ36717272
A physical map of two clusters containing the genes for six proinflammatory receptorsQ36733867
cDNA cloning of a G-protein-coupled receptor expressed in rat spinal cord and brain related to chemokine receptorsQ36735725
Molecular cloning, characterization, and localization of the human homolog to the reported bovine NPY Y3 receptor: lack of NPY binding and activationQ36764768
Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteinsQ36766113
Cloning of a novel putative G-protein-coupled receptor (NLR) which is expressed in neuronal and lymphatic tissueQ36771144
Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4.Q36792249
Properties of the novel proinflammatory supergene "intercrine" cytokine family.Q37357898
Purification of the active C5a receptor from human polymorphonuclear leukocytes as a receptor-Gi complexQ37390308
Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytesQ37592968
Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interactionQ38287747
Platelet-activating factor induces NF-kappa B activation through a G protein-coupled pathwayQ38294171
Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptorQ28297700
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleenQ28300225
The structure-activity relations of synthetic peptides as chemotactic factors and inducers of lysosomal secretion for neutrophilsQ28342223
Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptorQ28369186
G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cellsQ28611547
CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1Q28646859
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor geneQ29614892
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infectionQ29614956
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1Q29616092
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5Q29616094
Leukotrienes and lipoxins: structures, biosynthesis, and biological effectsQ29617543
Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunitsQ30826586
Cloning and functional expression of the canine anaphylatoxin C5a receptor. Evidence for high interspecies variabilityQ33196760
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsinQ33669928
Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesisQ33829523
N-formylmethionyl peptides as chemoattractants for leucocytesQ33912714
Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppressionQ33941230
Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residuesQ34059219
Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocationQ34218574
FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinaseQ34229526
Inhibition of receptor-mediated release of arachidonic acid by pertussis toxinQ34245525
Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophilsQ34252985
Three-dimensional structure of interleukin 8 in solutionQ27671809
Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopyQ27684426
Crystal structure of recombinant human platelet factor 4Q27730824
High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMRQ27731247
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinaseQ28115936
Synthesis and use of a novel N-formyl peptide derivative to isolate a human N-formyl peptide receptor cDNAQ28116184
cDNA cloning of a novel G protein-coupled receptor with a large extracellular loop structureQ28116827
A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactorsQ28118386
Cloning of the gene coding for a human receptor for formyl peptides. Characterization of a promoter region and evidence for polymorphic expressionQ28203457
Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complementQ28237531
Stabilization of C5a receptor--G-protein interactions through ligand bindingQ28241039
The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptorsQ28243582
C5A anaphylatoxin and its seven transmembrane-segment receptorQ28243792
Monomer-dimer equilibria of interleukin-8 and neutrophil-activating peptide 2. Evidence for IL-8 binding as a dimer and oligomer to IL-8 receptor BQ28254369
G protein-coupled signal transduction pathways for interleukin-8Q28259879
Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleenQ28260321
Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor geneQ28263051
Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2Q28263123
Two different promoters direct expression of two distinct forms of mRNAs of human platelet-activating factor receptorQ28263300
Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19Q28269315
Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cellsQ28270680
Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophiliaQ28275791
Selective G protein coupling by C-C chemokine receptorsQ28278383
Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3Q28278947
The chemotactic receptor for human C5a anaphylatoxinQ28280054
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolatesQ28282895
Expression of the chemokine receptor BLR2/EBI1 is specifically transactivated by Epstein-Barr virus nuclear antigen 2Q28284326
Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factorQ28289854
The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissuesQ28291583
Cloning and functional expression of a human eosinophil CC chemokine receptorQ28294129
Identification of the Major Phosphorylation Sites in Human C5a Anaphylatoxin Receptor in VivoQ28295613
Cloning, chromosomal localization, and RNA expression of a human beta chemokine receptor-like geneQ28295734
Cloning of complementary DNA encoding a functional human interleukin-8 receptorQ28297523
Platelet-activating factor stimulates transcription of the heparin-binding epidermal growth factor-like growth factor in monocytes. Correlation with an increased kappa B binding activityQ38296767
Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-kappa B.Q38301334
Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptorQ38311633
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomasQ38315242
The G protein-coupled receptor BLR1 is involved in murine B cell differentiation and is also expressed in neuronal tissuesQ38315413
Structure, 5'-flanking sequence, and chromosome location of the human N-formyl peptide receptor gene. A single-copy gene comprised of two exons on chromosome 19q.13.3 that yields two distinct transcripts by alternative polyadenylationQ38319904
Detection of multiple forms of Gi alpha in HL60 cellsQ38348831
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificityQ39413074
Platelet activating factor: a biologically active phosphoglycerideQ39503946
Red blood cells are a sink for interleukin 8, a leukocyte chemotaxinQ40342411
Juxtacrine intercellular signaling: another way to do it.Q40384623
Anaphylatoxin inactivator of human plasma: its isolation and characterization as a carboxypeptidase.Q40475508
Low-molecular-weight GTP-binding proteins and leukocyte signal transductionQ40477303
Signals and receptors involved in recruitment of inflammatory cellsQ40522208
Structure-activity relationships of chemokinesQ40531026
The molecular biology of leukocyte chemoattractant receptorsQ40661169
Chemokine receptors and molecular mimicryQ40693177
A common step for signal transduction in G protein-coupled receptorsQ40706810
Phospholipases and protein kinases during phagocyte activationQ40747743
Emerging concepts in the Ras superfamily of GTP-binding proteins.Q40824986
Phospholipase D and cell signalingQ40852195
The probable arrangement of the helices in G protein-coupled receptors.Q40872681
Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell linesQ41157521
Identification of a mouse eosinophil receptor for the CC chemokine eotaxinQ41190661
Extension of recombinant human RANTES by the retention of the initiating methionine produces a potent antagonist.Q41229926
Site-directed mutagenesis of conserved charged residues in the helical region of the human C5a receptor. Arg2O6 determines high-affinity binding sites of C5a receptorQ41238812
Cross-desensitization of chemoattractant receptors occurs at multiple levels. Evidence for a role for inhibition of phospholipase C activityQ41270179
Regulation of Human Interleukin-8 Receptor A: Identification of a Phosphorylation Site Involved in Modulating Receptor FunctionsQ41280416
Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microgliaQ41321312
Probing the "message:address" sites for chemoattractant binding to the C5a receptor. Mutagenesis of hydrophilic and proline residues within the transmembrane segmentsQ41323110
Mutation of glutamate 199 of the human C5a receptor defines a binding site for ligand distinct from the receptor N terminusQ41325958
Differential coupling of the formyl peptide receptor to adenylate cyclase and phospholipase C by the pertussis toxin-insensitive Gz proteinQ41330429
N-formylpeptide and complement C5a receptors are expressed in liver cells and mediate hepatic acute phase gene regulationQ41332938
Binding of low affinity N-formyl peptide receptors to G protein. Characterization of a novel inactive receptor intermediateQ41346960
Activation of protein kinase C enhances the phosphorylation of the type B interleukin-8 receptor and stimulates its degradation in non-hematopoietic cellsQ41346982
The role of Tyr13 and Lys15 of interleukin-8 in the high affinity interaction with the interleukin-8 receptor type A.Q41346989
The human chemoattractant complement C5a receptor inhibits cyclic AMP accumulation through Gi and Gz proteinsQ41361165
Functional analysis of a dominant negative mutant of G alpha i2.Q41368028
The role of the third intracellular loop of the neutrophil N-formyl peptide receptor in G protein couplingQ41529517
Selective coupling of the human anaphylatoxin C5a receptor and alpha 16 in human kidney 293 cellsQ41553152
Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase CQ41589223
Cloning by functional expression of platelet-activating factor receptor from guinea-pig lungQ41699178
Characterization and species distribution of high affinity GTP-coupled receptors for human rantes and monocyte chemoattractant protein 1Q41851917
Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptorQ42109345
Further studies on the structural requirements for synthetic peptide chemoattractantsQ42272224
Agonist-sensitive binding of a photoreactive GTP analog to a G-protein alpha-subunit in membranes of HL-60 cellsQ42479282
Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophilsQ42514685
Eotaxin: cloning of an eosinophil chemoattractant cytokine and increased mRNA expression in allergen-challenged guinea-pig lungs.Q42596329
DNA sequence analysis of conserved and unique regions of swinepox virus: identification of genetic elements supporting phenotypic observations including a novel G protein-coupled receptor homologueQ42609750
Sequence analysis of HindIII Q2 fragment of capripoxvirus reveals a putative gene encoding a G-protein-coupled chemokine receptor homologueQ42684080
Characterization of specific binding sites of 3H-labelled platelet-activating factor ([3H]PAF) and a new antagonist, [3H]SR 27417, on guinea-pig tracheal epithelial cellsQ42797984
Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclinsQ43566357
Selective inhibition of N-formylpeptide-induced neutrophil activation by carbamate-modified peptide analoguesQ43600268
Two adjacent cysteine residues in the C-terminal cytoplasmic fragment of bovine rhodopsin are palmitylatedQ44241904
The chemokine, eotaxin, activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivoQ46987094
Cloning and differential tissue-specific expression of three mouse beta chemokine receptor-like genes, including the gene for a functional macrophage inflammatory protein-1 alpha receptorQ48072070
Human cytomegalovirus encodes three G protein-coupled receptor homologuesQ48269680
Stimulation of phospholipase C by guanine-nucleotide-binding protein beta gamma subunitsQ48468552
Synthetic C5a receptor agonists. Pharmacology, metabolism and in vivo cardiovascular and hematologic effects.Q54244808
Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural GeneQ56591978
CXC Chemokines Bind to Unique Sets of Selectivity Determinants That Can Function Independently and Are Broadly Distributed on Multiple Domains of Human Interleukin-8 Receptor BQ56595237
Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8Q57904870
P304page(s)221-289
P577publication date1997-01-01
P1433published inAdvances in PharmacologyQ15753809
P1476titleStructure and function of leukocyte chemoattractant receptors
P478volume39

Reverse relations

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