| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2001PNAS...98.9255X |
| P356 | DOI | 10.1073/PNAS.151173398 |
| P932 | PMC publication ID | 55407 |
| P698 | PubMed publication ID | 11481486 |
| P5875 | ResearchGate publication ID | 11860557 |
| P50 | author | Jeannette M. Bonifas | Q107438263 |
| Michelle Aszterbaum | Q107438679 | ||
| P2093 | author name string | X Zhang | |
| E Epstein | |||
| F McCormick | |||
| J Xie | |||
| C Zachary | |||
| P2860 | cites work | Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1 | Q22010791 |
| Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli | Q22010803 | ||
| Activating Smoothened mutations in sporadic basal-cell carcinoma | Q24318403 | ||
| The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog | Q24318676 | ||
| Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome | Q24336457 | ||
| Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1 | Q24678635 | ||
| Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours | Q28253060 | ||
| Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system | Q28270384 | ||
| Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome | Q28273158 | ||
| Human homolog of patched, a candidate gene for the basal cell nevus syndrome | Q28281033 | ||
| The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas | Q28288407 | ||
| Altered neural cell fates and medulloblastoma in mouse patched mutants | Q28588056 | ||
| Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1 | Q28591305 | ||
| Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections | Q33263235 | ||
| UV-specific mutations of the human patched gene in basal cell carcinomas from normal individuals and xeroderma pigmentosum patients | Q33933775 | ||
| Biochemical evidence that patched is the Hedgehog receptor | Q34406394 | ||
| Platelet-derived growth factor alpha receptor gene expression: isolation and characterization of the promoter and upstream regulatory elements | Q35613078 | ||
| Journey to the surface of the cell: Fos regulation and the SRE | Q38579800 | ||
| Nevoid basal-cell carcinoma syndrome | Q39759038 | ||
| Activators and effectors of ras p21 proteins | Q40757563 | ||
| Transcriptional activity of GLI1 is negatively regulated by protein kinase A. | Q40855158 | ||
| Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours | Q41099186 | ||
| Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors | Q41104609 | ||
| Sonic hedgehog signaling by the patched-smoothened receptor complex | Q41607067 | ||
| Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice | Q41699926 | ||
| Sporadic medulloblastomas contain PTCH mutations. | Q42434884 | ||
| Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. | Q42440473 | ||
| Trichoepitheliomas contain somatic mutations in the overexpressed PTCH gene: support for a gatekeeper mechanism in skin tumorigenesis. | Q42446362 | ||
| Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome | Q42455110 | ||
| Transducing Hedgehog: the story so far | Q42457520 | ||
| Basal cell carcinoma development is associated with induction of the expression of the transcription factor Gli-1. | Q42466793 | ||
| A frequent activated smoothened mutation in sporadic basal cell carcinomas | Q42467910 | ||
| Epithelial-stromal interactions in basal cell cancer: the PDGF system | Q42498519 | ||
| Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation | Q42524410 | ||
| Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. | Q52200237 | ||
| Lipopolysaccharide up-regulates platelet-derived growth factor (PDGF) alpha-receptor expression in rat lung myofibroblasts and enhances response to all PDGF isoforms | Q71120581 | ||
| The works of GLI and the power of hedgehog | Q73177916 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 9255-9 | |
| P577 | publication date | 2001-07-31 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | A role of PDGFRalpha in basal cell carcinoma proliferation | |
| P478 | volume | 98 |
| Q35925815 | A Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction. |
| Q52646455 | A highlight on Sonic hedgehog pathway. |
| Q37277962 | A list of candidate cancer biomarkers for targeted proteomics |
| Q37249645 | A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway |
| Q44189308 | A regulating element essential for PDGFRA transcription is recognized by neural tube defect-associated PRX homeobox transcription factors. |
| Q36368350 | A role for transcription factor STAT3 signaling in oncogene smoothened-driven carcinogenesis |
| Q36420668 | ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage |
| Q39691759 | Activation of Sonic hedgehog signaling pathway in S-type neuroblastoma cell lines |
| Q24806212 | Activation of the hedgehog pathway in advanced prostate cancer |
| Q54616323 | Activation of the hedgehog pathway in human hepatocellular carcinomas. |
| Q37638143 | Activation of the hedgehog-signaling pathway in human cancer and the clinical implications |
| Q42863151 | Akt1 interacts with epidermal growth factor receptors and hedgehog signaling to increase stem/transit amplifying cells in the embryonic mouse cortex |
| Q42430947 | Antitumor effect of MAb EMD 55900 depends on EGF-R expression and histopathology |
| Q38602543 | Basal cell carcinoma of the skin (part 1): epidemiology, pathology and genetic syndromes |
| Q34495423 | Basal cell carcinoma: from the molecular understanding of the pathogenesis to targeted therapy of progressive disease |
| Q35687900 | Basal cell carcinomas: attack of the hedgehog |
| Q35108046 | Clinical implications of hedgehog signaling pathway inhibitors |
| Q36926998 | Combining hedgehog signaling inhibition with focal irradiation on reduction of pancreatic cancer metastasis |
| Q42527313 | Comparison of the expression of p53, p21, Bax and the induction of apoptosis between patients with basal cell carcinoma and normal controls in response to ultraviolet irradiation. |
| Q39158937 | Cutaneous carcinosarcoma: further insights into its mutational landscape through massive parallel genome sequencing |
| Q40132437 | De-regulation of the sonic hedgehog pathway in the InsGas mouse model of gastric carcinogenesis |
| Q38252545 | Development of astrocytes in the vertebrate eye |
| Q33931827 | Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development |
| Q39644572 | Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases |
| Q42093825 | Evidence of EGR1 as a differentially expressed gene among proliferative skin diseases |
| Q42518784 | Expression of NCAM (CD56), chromogranin A, synaptophysin, c-KIT (CD117) and PDGFRA in normal non-neoplastic skin and basal cell carcinoma: an immunohistochemical study of 66 consecutive cases |
| Q43059528 | Fibroblast growth factor-hedgehog interdependence during retina regeneration |
| Q34244929 | Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies |
| Q35789048 | Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosis |
| Q36855733 | G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation. |
| Q47258214 | GANT-61 and GDC-0449 induce apoptosis of prostate cancer stem cells through a GLI-dependent mechanism. |
| Q34129830 | GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft |
| Q50489835 | GLI1+ progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue. |
| Q24653046 | GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cells |
| Q34665999 | Gli and hedgehog in cancer: tumours, embryos and stem cells. |
| Q28078559 | Glucose transport: meeting the metabolic demands of cancer, and applications in glioblastoma treatment |
| Q38845233 | Hedgehog Gli signalling in kidney fibrosis |
| Q99591085 | Hedgehog Signaling and Truncated GLI1 in Cancer |
| Q39623310 | Hedgehog signaling drives cellular survival in human colon carcinoma cells |
| Q34291589 | Hedgehog signalling in cancer formation and maintenance |
| Q36553688 | Hedgehog signalling in skin development and cancer |
| Q38253645 | Hedgehog signalling pathway: carcinogenesis and targeted therapy |
| Q35780214 | Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma |
| Q40612672 | IFNalpha induces Fas expression and apoptosis in hedgehog pathway activated BCC cells through inhibiting Ras-Erk signaling |
| Q35108140 | Identification of signature genes for detecting hedgehog pathway activation in esophageal cancer |
| Q35108082 | Identification of signature genes for detecting hedgehog signaling activation in gastric cancer |
| Q39997955 | Identification, functional characterization, and pathobiological significance of GLI1 isoforms in human cancers |
| Q42467743 | Immunolocalization of glioma-associated oncogene homolog 1 in non melanoma skin cancer |
| Q38014084 | Immunotherapy in nonmelanoma skin cancer |
| Q36836283 | Implications of hedgehog signaling antagonists for cancer therapy |
| Q34510184 | Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit. |
| Q47756210 | Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis |
| Q40249166 | Long-term establishment, characterization and manipulation of cell lines from mouse basal cell carcinoma tumors |
| Q37923514 | Mechanisms of Hedgehog signalling in cancer |
| Q38386429 | Mechanisms regulating glioma invasion |
| Q35722779 | Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways. |
| Q35891213 | MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1. |
| Q46147844 | Microparticles harboring Sonic Hedgehog promote angiogenesis through the upregulation of adhesion proteins and proangiogenic factors |
| Q42471975 | Molecular diagnosis of basal cell carcinoma and other basaloid cell neoplasms of the skin by the quantification of Gli1 transcript levels. |
| Q21132689 | NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo |
| Q38886252 | Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1+/- /SKH-1 Hairless Mice |
| Q38225894 | New insight into hedgehog signaling in hematological malignancies |
| Q36297949 | Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway |
| Q42165194 | Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells |
| Q36752431 | Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice |
| Q33260784 | PDGFR-alpha as a potential therapeutic target in uterine sarcomas |
| Q33688428 | PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation |
| Q40355706 | PI3K-AKT signaling is a downstream effector of retinoid prevention of murine basal cell carcinogenesis |
| Q34653250 | PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation |
| Q88990691 | Patched-2 functions to limit Patched-1 deficient skin cancer growth |
| Q36040432 | Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis |
| Q26775134 | Profile of nintedanib in the treatment of solid tumors: the evidence to date |
| Q42807908 | Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal |
| Q92142489 | SHARPIN regulates cell proliferation of cutaneous basal cell carcinoma via inactivation of the transcriptional factors GLI2 and c‑JUN |
| Q58113158 | Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis |
| Q37356915 | Sonic hedgehog in gastric physiology and neoplastic transformation: friend or foe? |
| Q28572747 | Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo |
| Q34099331 | Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas |
| Q26829546 | Structural and functional properties of platelet-derived growth factor and stem cell factor receptors |
| Q43194318 | Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway |
| Q37232227 | Targeting hedgehog signaling in cancer: research and clinical developments |
| Q34393461 | Targeting the PDGF signaling pathway in tumor treatment |
| Q40034798 | The EWS/FLI1 oncogenic transcription factor deregulates GLI1. |
| Q36240079 | The Hedgehog pathway: role in cell differentiation, polarity and proliferation |
| Q37371674 | The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin |
| Q38044769 | The sonic hedgehog-GLI1 signaling pathway in brain tumor development. |
| Q28235717 | The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells |
| Q34064658 | Toll-like receptor 3 regulates neural stem cell proliferation by modulating the Sonic Hedgehog pathway |
| Q34233512 | Transactivation of platelet-derived growth factor receptor alpha by the GTPase-deficient activated mutant of Galpha12. |
| Q36538369 | Versican: signaling to transcriptional control pathways. |
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