| P2093 | author name string | Tania Cristina Leite de Sampaio E Spohr | |
| | Gabriela Basile Carballo | |
| | Giselle Pinto Farias de Lopes | |
| | Jéssica Ribeiro Honorato | |
| P2860 | cites work | Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation. | Q51356350 |
| | Loss of suppressor-of-fused function promotes tumorigenesis. | Q53334228 |
| | Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response. | Q53589777 |
| | Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer | Q83184162 |
| | Cancer stem cells: an evolving concept | Q83213559 |
| | Hedgehog signaling pathway as a therapeutic target for ovarian cancer | Q87003714 |
| | First-in-class, first-in-human phase I results of targeted agents: highlights of the 2008 American society of clinical oncology meeting | Q21198874 |
| | Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1 | Q22010791 |
| | Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb | Q22253250 |
| | Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells | Q24290219 |
| | Suppressing Wnt signaling by the hedgehog pathway through sFRP-1 | Q24306581 |
| | Distinct roles of PTCH2 splice variants in Hedgehog signalling | Q24530681 |
| | A role of PDGFRalpha in basal cell carcinoma proliferation | Q24555827 |
| | The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins | Q24605731 |
| | Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway | Q24623800 |
| | MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression | Q24683830 |
| | Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors | Q26764892 |
| | Hedgehog Signaling in the Maintenance of Cancer Stem Cells | Q26798191 |
| | EGFR and downstream genetic alterations in KRAS/BRAF and PI3K/AKT pathways in colorectal cancer: implications for targeted therapy | Q26830672 |
| | Neural stem cell niches in health and diseases | Q26995185 |
| | Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma | Q27860910 |
| | Gliomas and the vascular fragility of the blood brain barrier | Q28081953 |
| | Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling | Q28141240 |
| | Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1 | Q28215795 |
| | Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma | Q28236409 |
| | Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo | Q28237073 |
| | Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours | Q28253060 |
| | Microglia-glioblastoma interactions: New role for Wnt signaling. | Q39336553 |
| | Hedgehog Controls Quiescence and Activation of Neural Stem Cells in the Adult Ventricular-Subventricular Zone. | Q39352964 |
| | Hedgehog signaling in mouse ovary: Indian hedgehog and desert hedgehog from granulosa cells induce target gene expression in developing theca cells | Q39592664 |
| | Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance | Q39625099 |
| | Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation | Q39750898 |
| | Gli1 is a potential target for alleviating multidrug resistance of gliomas | Q39789135 |
| | Crosstalk of hedgehog and Wnt pathways in gastric cancer | Q40017476 |
| | Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport | Q40160149 |
| | Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis | Q40212310 |
| | Enhancement of GLI1-transcriptional activity by beta-catenin in human cancer cells. | Q40265271 |
| | Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes. | Q40464669 |
| | Transcriptional activity of GLI1 is negatively regulated by protein kinase A. | Q40855158 |
| | The Crossroads of Neural Stem Cell Development and Tumorigenesis | Q41283587 |
| | Catching a Gli-mpse of Hedgehog | Q41551870 |
| | Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449 | Q42031842 |
| | Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells | Q42165194 |
| | Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor. | Q42378333 |
| | Gli1 is important for medulloblastoma formation in Ptc1+/- mice | Q42476399 |
| | Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling | Q42805992 |
| | Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. | Q43121364 |
| | The DNA repair protein, O(6)-methylguanine-DNA methyltransferase is a proteolytic target for the E6 human papillomavirus oncoprotein. | Q44107669 |
| | Hedgehog/Gli1 signaling pathway regulates MGMT expression and chemoresistance to temozolomide in human glioblastoma | Q47100546 |
| | Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics | Q47820263 |
| | Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma. | Q48027338 |
| | Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine | Q48479768 |
| | Hedgehog-GLI pathway in medulloblastoma | Q48564859 |
| | A systematic review and meta-analysis: Association between MGMT hypermethylation and the clinicopathological characteristics of non-small-cell lung carcinoma | Q49165105 |
| | A phase II trial of arsenic trioxide and temozolomide in combination with radiation therapy for patients with malignant gliomas | Q38782719 |
| | Primary Cilia and Mammalian Hedgehog Signaling | Q39018423 |
| | Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat. | Q39260254 |
| | Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells | Q28264780 |
| | Rapid clearance of psoriatic skin lesions induced by topical cyclopamine. A preliminary proof of concept study | Q28277547 |
| | Identification of an amplified, highly expressed gene in a human glioma | Q28300727 |
| | Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis | Q28505923 |
| | Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation | Q28507411 |
| | Suppressor of fused negatively regulates beta-catenin signaling | Q28510365 |
| | Sonic hedgehog regulates the growth and patterning of the cerebellum | Q28510489 |
| | Hedgehog signaling pathway is active in GBM with GLI1 mRNA expression showing a single continuous distribution rather than discrete high/low clusters | Q28544108 |
| | Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway | Q28575061 |
| | Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused | Q28587233 |
| | GSK3beta positively regulates Hedgehog signaling through Sufu in mammalian cells | Q28592576 |
| | Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway | Q28594509 |
| | Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened | Q28646558 |
| | The primary cilium: a signalling centre during vertebrate development | Q29547197 |
| | ras oncogenes in human cancer: a review | Q29547769 |
| | Ubiquitin and ubiquitin-like proteins as multifunctional signals | Q30014838 |
| | The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer | Q30252204 |
| | Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide | Q34000287 |
| | Inhibition of the hedgehog pathway in advanced basal-cell carcinoma | Q34019208 |
| | The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction. | Q34067275 |
| | Small-molecule modulators of the Sonic Hedgehog signaling pathway. | Q34089131 |
| | Specification of neuronal fates in the ventral neural tube | Q34141441 |
| | Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity | Q34146314 |
| | Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies | Q34244929 |
| | Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling | Q34312510 |
| | Sertoli cell signaling by Desert hedgehog regulates the male germline | Q34396888 |
| | Smoothened Regulation: A Tale of Two Signals | Q34496658 |
| | Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway | Q34561698 |
| | Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling | Q34574774 |
| | Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway | Q34658803 |
| | The Gli code: an information nexus regulating cell fate, stemness and cancer. | Q34685494 |
| | Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord | Q34693534 |
| | Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1 | Q34769889 |
| | Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network | Q34795340 |
| | Heterotrimeric Gi proteins link Hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration | Q35010997 |
| | Targeting the Hedgehog pathway in cancer | Q35076275 |
| | Hedgehog signaling promotes medulloblastoma survival via Bc/II | Q35570435 |
| | Hedgehog: an unusual signal transducer | Q35731063 |
| | Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists | Q35785923 |
| | Prevalence estimates for primary brain tumors in the United States by behavior and major histology groups | Q35894781 |
| | Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update | Q35904534 |
| | Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened | Q35987233 |
| | TGF-beta, neuronal stem cells and glioblastoma | Q36241240 |
| | Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma | Q36474588 |
| | The cancer stem cell hypothesis: a work in progress | Q36639832 |
| | Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation | Q36713352 |
| | Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner | Q36976060 |
| | The availability of the embryonic TGF-β protein Nodal is dynamically regulated during glioblastoma multiforme tumorigenesis | Q37018171 |
| | Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy | Q37269674 |
| | The relationship between early embryo development and tumourigenesis | Q37294300 |
| | Phase I study of vismodegib in children with recurrent or refractory medulloblastoma: a pediatric brain tumor consortium study | Q37375947 |
| | Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus | Q37465396 |
| | Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes | Q37469921 |
| | Hedgehog beyond medulloblastoma and basal cell carcinoma | Q37677865 |
| | Sonic hedgehog functions through dynamic changes in temporal competence in the developing forebrain | Q37751487 |
| | Maintenance and differentiation of neural stem cells | Q37808164 |
| | Glioblastoma cells: a heterogeneous and fatal tumor interacting with the parenchyma | Q37885016 |
| | Gli proteins in development and disease | Q37908115 |
| | The brain tumor microenvironment. | Q37989468 |
| | Hedgehog/Gli control by ubiquitination/acetylation interplay. | Q37990685 |
| | Glioblastoma: therapeutic challenges, what lies ahead | Q38017008 |
| | The Hedgehog signal transduction network | Q38052884 |
| | Essential role of Gli proteins in glioblastoma multiforme. | Q38094725 |
| | Nonclassical hedgehog-GLI signaling and its clinical implications | Q38127609 |
| | Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells. | Q38131219 |
| | Discovery and preclinical development of vismodegib | Q38214255 |
| | Sonic hedgehog signalling pathway: a complex network | Q38247955 |
| | Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes. | Q38409513 |
| | Hijacking the Hedgehog Pathway in Cancer Therapy | Q38600795 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P921 | main subject | peptide | Q172847 |
| | signal transduction | Q828130 |
| | hedgehog protein | Q24768159 |
| P304 | page(s) | 11 | |
| P577 | publication date | 2018-03-20 | |
| P1433 | published in | Cell Communication and Signaling | Q1254390 |
| P1476 | title | A highlight on Sonic hedgehog pathway. | |
| P478 | volume | 16 | |