| scholarly article | Q13442814 |
| P2093 | author name string | Matthew P Scott | |
| Ljiljana Milenkovic | |||
| Rajat Rohatgi | |||
| Eric W Humke | |||
| Karolin V Dorn | |||
| P2860 | cites work | Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function | Q21145277 |
| Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli | Q22010803 | ||
| Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb | Q22253250 | ||
| Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing | Q24299566 | ||
| Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex | Q24534137 | ||
| Small molecule modulation of Smoothened activity | Q24540343 | ||
| Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis | Q24633064 | ||
| Vertebrate Smoothened functions at the primary cilium | Q27919682 | ||
| Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine | Q28138510 | ||
| Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2 | Q28186976 | ||
| Characterization of the physical interaction of Gli proteins with SUFU proteins | Q28214496 | ||
| Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1 | Q28215795 | ||
| Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates | Q28285927 | ||
| Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors | Q28509134 | ||
| Cilia and Hedgehog responsiveness in the mouse | Q28585101 | ||
| Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved | Q28585804 | ||
| Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused | Q28587233 | ||
| Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1 | Q28591305 | ||
| Hedgehog signalling in the mouse requires intraflagellar transport proteins | Q28593010 | ||
| Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway | Q28594509 | ||
| Patched1 regulates hedgehog signaling at the primary cilium | Q29547515 | ||
| Production of high-titer helper-free retroviruses by transient transfection | Q29547802 | ||
| Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms | Q29614613 | ||
| Hedgehog: functions and mechanisms | Q29619190 | ||
| Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster | Q33960123 | ||
| Mutations in SUFU predispose to medulloblastoma | Q34133729 | ||
| Activation of heterotrimeric G proteins by Smoothened | Q35033814 | ||
| The proteasome: a utility tool for transcription? | Q36406913 | ||
| G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling | Q37348019 | ||
| Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus | Q37465396 | ||
| Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation. | Q39721420 | ||
| DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine | Q39915098 | ||
| Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression | Q40933908 | ||
| Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP. | Q41493138 | ||
| Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia | Q42011206 | ||
| Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators | Q42429067 | ||
| Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base. | Q42464520 | ||
| Separation and detection of large phosphoproteins using Phos-tag SDS-PAGE. | Q43268254 | ||
| Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor | Q44894172 | ||
| Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus. | Q45345886 | ||
| Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator | Q47070726 | ||
| A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. | Q47071852 | ||
| Sufu recruits GSK3beta for efficient processing of Gli3. | Q50336964 | ||
| Identification of a SUFU germline mutation in a family with Gorlin syndrome. | Q51932422 | ||
| Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. | Q52165850 | ||
| Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. | Q52178240 | ||
| The subcellular localization and activity of Drosophila cubitus interruptus are regulated at multiple levels. | Q52573765 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | GLI-Kruppel family member GLI3 | Q14886933 |
| SUFU negative regulator of hedgehog signaling | Q21495920 | ||
| P304 | page(s) | 670-82 | |
| P577 | publication date | 2010-04-01 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins | |
| P478 | volume | 24 |
| Q35745269 | A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response |
| Q40078193 | A Notch-Gli2 axis sustains Hedgehog responsiveness of neural progenitors and Müller glia. |
| Q36650564 | A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia |
| Q35509854 | A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome |
| Q37674685 | A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity |
| Q35877495 | A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo. |
| Q36050816 | A crucial requirement for Hedgehog signaling in small cell lung cancer |
| Q52646455 | A highlight on Sonic hedgehog pathway. |
| Q42407472 | A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes |
| Q28594488 | A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling |
| Q46215286 | A prospective study of the clinical utility of prenatal chromosomal microarray analysis in fetuses with ultrasound abnormalities and an exploration of a framework for reporting unclassified variants and risk factors. |
| Q91725342 | A proteomic approach identifies SAFB-like transcription modulator (SLTM) as a bidirectional regulator of GLI family zinc finger transcription factors |
| Q48215997 | A synthetic combinatorial approach to disabling deviant Hedgehog signaling |
| Q90029083 | ARL13B regulates Sonic hedgehog signaling from outside primary cilia |
| Q64233929 | Abnormal activity of transcription factors gli in high-grade gliomas |
| Q33790684 | Advanced treatment for basal cell carcinomas |
| Q35589229 | An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibition |
| Q28392205 | An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer |
| Q34483092 | Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling |
| Q47189018 | Anti-fibrotic effects of pirfenidone by interference with the hedgehog signalling pathway in patients with systemic sclerosis-associated interstitial lung disease. |
| Q34002623 | Arhgap36-dependent activation of Gli transcription factors |
| Q28586066 | Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins |
| Q47685017 | Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion |
| Q24301377 | BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes |
| Q34341781 | BMP-mediated induction of GATA4/5/6 blocks somitic responsiveness to SHH. |
| Q38014318 | Basic biology and mechanisms of neural ciliogenesis and the B9 family |
| Q91729476 | Bicyclic imidazolium inhibitors of Gli transcription factor activity |
| Q39150566 | CK1 in Developmental Signaling: Hedgehog and Wnt. |
| Q47241729 | CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog |
| Q54959590 | Canonical Sonic Hedgehog Signaling in Early Lung Development. |
| Q38215035 | Canonical and non-canonical Hedgehog signalling and the control of metabolism |
| Q91410919 | Cellular signalling by primary cilia in development, organ function and disease |
| Q42323404 | Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function |
| Q33877283 | Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathways |
| Q26829929 | Cilia functions in development |
| Q34173153 | Cilia in the CNS: the quiet organelle claims center stage |
| Q26829114 | Cilia in vertebrate development and disease |
| Q38912342 | Cilia-dependent GLI processing in neural crest cells is required for tongue development |
| Q38230974 | Cilia: traffic directors along the road of cortical development |
| Q36118401 | Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent |
| Q35157465 | Contributions of Costal 2-Fused interactions to Hedgehog signaling in Drosophila |
| Q55417331 | Control of Hedgehog Signalling by the Cilia-Regulated Proteasome. |
| Q30994124 | Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary cilium |
| Q36179242 | Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline. |
| Q89542590 | Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds |
| Q27021981 | Decoding the phosphorylation code in Hedgehog signal transduction |
| Q92634454 | Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities |
| Q38214832 | Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis? |
| Q89393752 | Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo |
| Q33931827 | Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development |
| Q38688231 | Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model |
| Q64231812 | Distinct Activities of Gli1 and Gli2 in the Absence of Ift88 and the Primary Cilia |
| Q37256791 | Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma. |
| Q104139662 | Dl-3-n-butylphthalide Promotes Neurite Outgrowth of Primary Cortical Neurons by Sonic Hedgehog Signaling via Upregulating Gap43 |
| Q51889147 | Don't hedge your bets: hedgehog signaling as a central mediator of endochondral bone development and cartilage diseases. |
| Q37306391 | Drugging the Cancer Stem Cell Compartment: Lessons Learned from the Hedgehog and Wnt Signal Transduction Pathways |
| Q34787314 | Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium |
| Q53394164 | Dual function of suppressor of fused in Hh pathway activation and mouse spinal cord patterning. |
| Q42504214 | Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision |
| Q33112271 | EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia |
| Q92153532 | ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP |
| Q35444326 | Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas |
| Q36233930 | Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice |
| Q38257711 | Epigenetic pathways and glioblastoma treatment: insights from signaling cascades |
| Q90643291 | Epiphyseal Cartilage Formation Involves Differential Dynamics of Various Cellular Populations During Embryogenesis |
| Q42439705 | Evasion of p53 and G2/M checkpoints are characteristic of Hh-driven basal cell carcinoma. |
| Q42796344 | Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor. |
| Q40963789 | Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis |
| Q28507517 | Functional characterization of putative cilia genes by high-content analysis |
| Q50042900 | G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog. |
| Q55014626 | G-protein-coupled receptor signaling and neural tube closure defects. |
| Q50336980 | G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning |
| Q38213167 | G-protein-coupled receptors, Hedgehog signaling and primary cilia |
| Q28538554 | GATA6 is a crucial regulator of Shh in the limb bud |
| Q50298975 | GLI proteins are phosphorylated |
| Q50298918 | GLI proteins bind SUFU |
| Q50298974 | GLI translocates to the nucleus |
| Q47706903 | GLI1 inactivation is associated with developmental phenotypes overlapping with Ellis-van Creveld syndrome. |
| Q50298983 | GLI2,3 are degraded by the proteasome |
| Q50298970 | GLI:SUFU dissociates |
| Q50298969 | GLI:SUFU translocates to the ciliary tip in response to Hh signaling |
| Q50298959 | GPR161 is internalized |
| Q37215386 | Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling. |
| Q35726310 | Genome-wide single-nucleotide polymorphism analysis revealed SUFU suppression of acute graft-versus-host disease through downregulation of HLA-DR expression in recipient dendritic cells |
| Q64245029 | Gli Proteins: Regulation in Development and Cancer |
| Q41917900 | Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling. |
| Q37237607 | Gli-similar proteins: their mechanisms of action, physiological functions, and roles in disease. |
| Q100418580 | Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks |
| Q38935571 | Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy |
| Q99591085 | Hedgehog Signaling and Truncated GLI1 in Cancer |
| Q59792326 | Hedgehog Signaling in Cancer: A Prospective Therapeutic Target for Eradicating Cancer Stem Cells |
| Q38172812 | Hedgehog and Notch signaling in enteric nervous system development. |
| Q36317210 | Hedgehog pathway inhibition and the race against tumor evolution |
| Q38732773 | Hedgehog receptor function during craniofacial development |
| Q36002803 | Hedgehog secretion and signal transduction in vertebrates |
| Q38110992 | Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction |
| Q38695068 | Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction |
| Q34830946 | Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activator |
| Q46233034 | Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects. |
| Q28511590 | IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport |
| Q28588215 | Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs |
| Q36994787 | Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis |
| Q37158885 | Interaction of PACAP with Sonic hedgehog reveals complex regulation of the hedgehog pathway by PKA. |
| Q35280465 | Inversion of Sonic hedgehog action on its canonical pathway by electrical activity |
| Q52363961 | Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis. |
| Q36895367 | Kif3a is necessary for initiation and maintenance of medulloblastoma |
| Q41238772 | Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors |
| Q35605827 | Loss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant mice |
| Q33899466 | Mechanism and evolution of cytosolic Hedgehog signal transduction |
| Q28235875 | Mechanisms and functions of Hedgehog signalling across the metazoa |
| Q37923514 | Mechanisms of Hedgehog signalling in cancer |
| Q38169941 | Meckel-Gruber syndrome and the role of primary cilia in kidney, skeleton, and central nervous system development |
| Q42757909 | Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling. |
| Q36677081 | MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development. |
| Q38986584 | Microtubule Motors Drive Hedgehog Signaling in Primary Cilia |
| Q35063020 | Modulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused. |
| Q55249441 | Molecular mechanisms of suppressor of fused in regulating the hedgehog signalling pathway. |
| Q37082061 | Molecular pathways: the role of primary cilia in cancer progression and therapeutics with a focus on Hedgehog signaling |
| Q52721253 | Morphogen gradient reconstitution reveals Hedgehog pathway design principles. |
| Q26775531 | Morphogen rules: design principles of gradient-mediated embryo patterning |
| Q35644902 | Multisite interaction with Sufu regulates Ci/Gli activity through distinct mechanisms in Hh signal transduction |
| Q34795828 | Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma |
| Q35994811 | Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package |
| Q49045477 | Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma |
| Q35569650 | Neuropilins are positive regulators of Hedgehog signal transduction. |
| Q36168155 | Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth |
| Q38729673 | Non-melanoma skin cancer: new and future synthetic drug treatments. |
| Q83229291 | Notch signalling maintains Hedgehog responsiveness via a Gli-dependent mechanism during spinal cord patterning in zebrafish |
| Q28483973 | Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant |
| Q47562519 | Patched 1 Expression Correlates with Biochemical Relapse in High-Risk Prostate Cancer Patients. |
| Q47898096 | Patched1 is required in neural crest cells for the prevention of orofacial clefts |
| Q38509273 | Pharmacologic treatment options for advanced epithelial skin cancer |
| Q36040432 | Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis |
| Q37034988 | Phase II evaluation of IPI-926, an oral Hedgehog inhibitor, in patients with myelofibrosis |
| Q36059854 | Phosphodiesterase 4D acts downstream of Neuropilin to control Hedgehog signal transduction and the growth of medulloblastoma |
| Q96638233 | Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells |
| Q36372615 | Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis. |
| Q35067240 | Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo |
| Q39018423 | Primary Cilia and Mammalian Hedgehog Signaling |
| Q64084340 | Primary Cilium in Cancer Hallmarks |
| Q42053183 | Primary cilia act as mechanosensors during bone healing around an implant |
| Q35954406 | Primary cilia and Gli3 activity regulate cerebral cortical size |
| Q38116920 | Primary cilia and graded Sonic Hedgehog signaling |
| Q28593627 | Primary cilia are specialized calcium signalling organelles |
| Q27002324 | Primary cilia in the developing and mature brain |
| Q27011207 | Primary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengers |
| Q28512810 | Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube |
| Q37623787 | Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells |
| Q35407375 | Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms |
| Q38978119 | Pyrvinium attenuates Hedgehog signaling downstream of smoothened. |
| Q42730230 | Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway |
| Q38933688 | Regulation of Hedgehog Signalling Inside and Outside the Cell. |
| Q92701745 | Regulation of Hedgehog signaling Offers A Novel Perspective for Bone Homeostasis Disorder Treatment |
| Q36041364 | Regulation of Hedgehog signaling by ubiquitination |
| Q34518987 | Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling |
| Q54984935 | Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies. |
| Q34721114 | Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1 |
| Q34170706 | Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway |
| Q38768033 | SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. |
| Q50298982 | SPOP:CUL3:RBX1 ubiquitinates GLI2,3 |
| Q52726088 | Sending mixed signals: Cilia-dependent signaling during development and disease. |
| Q89831291 | Signaling in the primary cilium through the lens of the Hedgehog pathway |
| Q89638541 | Silica Perturbs Primary Cilia and Causes Myofibroblast Differentiation during Silicosis by Reduction of the KIF3A-Repressor GLI3 Complex |
| Q27321140 | Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1 |
| Q35874690 | Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein |
| Q34496658 | Smoothened Regulation: A Tale of Two Signals |
| Q36735740 | Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium |
| Q36387660 | Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2. |
| Q58790346 | Sonic Hedgehog Signaling Rises to the Surface: Emerging Roles in Neocortical Development |
| Q36802365 | Sonic Hedgehog Signaling and VACTERL Association |
| Q39462008 | Sonic hedgehog is cytoprotective against oxidative challenge in a cellular model of amyotrophic lateral sclerosis |
| Q34431127 | Sonic hedgehog signaling in the lung. From development to disease |
| Q35613389 | Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo |
| Q51056272 | Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord. |
| Q24311395 | Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation |
| Q28277263 | Structural basis of Smoothened regulation by its extracellular domains |
| Q24339542 | Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci |
| Q46016655 | Study on the skip metastasis of axillary lymph nodes in breast cancer and their relation with Gli1 expression. |
| Q50607969 | Sufu and Kif7 in limb patterning and development. |
| Q37595169 | Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling |
| Q90747107 | Suppressor of Fused Inhibits Skin Wound Healing |
| Q35637290 | Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin |
| Q47971385 | Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development |
| Q33874551 | Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors |
| Q37608723 | Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling |
| Q45360701 | Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina |
| Q36791953 | T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number |
| Q35168172 | T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor |
| Q64246334 | Targeting Hedgehog Signalling through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch |
| Q35987233 | Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened |
| Q48241938 | The Exon Junction Complex and Srp54 Contribute to Hedgehog Signaling via ci RNA Splicing in Drosophila melanogaster. |
| Q47313429 | The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner |
| Q47112797 | The Hedgehog Signaling Pathway Emerges as a Pathogenic Target |
| Q34747353 | The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation |
| Q38052884 | The Hedgehog signal transduction network |
| Q28081609 | The Hedgehog signalling pathway in bone formation |
| Q38374713 | The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation |
| Q50616390 | The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling. |
| Q36727479 | The Pluripotency Factor NANOG Binds to GLI Proteins and Represses Hedgehog-mediated Transcription |
| Q55363953 | The Role of Hedgehog Signalling in the Formation of the Ventricular Septum. |
| Q64092333 | The Role of Primary Cilia in the Crosstalk between the Ubiquitin⁻Proteasome System and Autophagy |
| Q34341702 | The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2. |
| Q26746930 | The cilia-regulated proteasome and its role in the development of ciliopathies and cancer |
| Q50336994 | The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia |
| Q34612216 | The ciliary protein Ftm is required for ventricular wall and septal development |
| Q48950926 | The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo |
| Q35054504 | The emerging face of primary cilia |
| Q33648406 | The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus. |
| Q33858596 | The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment |
| Q38110420 | The mechanisms of Hedgehog signalling and its roles in development and disease |
| Q36792187 | The relationship between sonic Hedgehog signaling, cilia, and neural tube defects |
| Q40839071 | The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. |
| Q47258866 | The role of the Hedgehog signaling pathway in cancer: A comprehensive review |
| Q41590284 | Tissue microarray analysis indicates hedgehog signaling as a potential prognostic factor in intermediate-risk prostate cancer |
| Q38051564 | Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile |
| Q30353488 | Trafficking to the primary cilium membrane. |
| Q38215036 | Transcriptional regulation of graded Hedgehog signaling |
| Q35348440 | Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus |
| Q38194970 | Tumor heterogeneity and cancer stem cell paradigm: updates in concept, controversies and clinical relevance. |
| Q55251323 | Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics. |
| Q37342555 | Understanding Mechanisms of GLI-Mediated Transcription during Craniofacial Development and Disease Using the Ciliopathic Mutant, talpid2. |
| Q48374383 | WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome |
| Q39209796 | WSS25 inhibits Dicer, downregulating microRNA-210, which targets Ephrin-A3, to suppress human microvascular endothelial cell (HMEC-1) tube formation |
| Q90266281 | Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer |
| Q50298981 | phosphorylated GLI proteins bind SPOP:CUL3:RBX1 |
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