scholarly article | Q13442814 |
P356 | DOI | 10.1172/JCI19876 |
10.1172/JCI200419876 | ||
P3181 | OpenCitations bibliographic resource ID | 4758273 |
P932 | PMC publication ID | 484972 |
P698 | PubMed publication ID | 15286800 |
P50 | author | Claude Knauf | Q42763449 |
Gavin Kelsey | Q48304318 | ||
Guy A. Rutter | Q56240272 | ||
Wendy Dean | Q60975980 | ||
Isabelle Leclerc | Q61090112 | ||
P2093 | author name string | Dan Ma | |
Julian P H Shield | |||
R éMy Burcelin R | |||
P2860 | cites work | Transcriptional activation capacity of the novel PLAG family of zinc finger proteins | Q24309016 |
Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain | Q24309817 | ||
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence | Q24311830 | ||
hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer | Q24317330 | ||
Transcriptional activities of the zinc finger protein Zac are differentially controlled by DNA binding | Q24540824 | ||
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas | Q24647944 | ||
The cell cycle control gene ZAC/PLAGL1 is imprinted--a strong candidate gene for transient neonatal diabetes | Q28143868 | ||
Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus | Q28213084 | ||
Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood | Q28217907 | ||
Identification of a gene containing zinc-finger motifs based on lost expression in malignantly transformed rat ovarian surface epithelial cells | Q28238567 | ||
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth | Q28508976 | ||
The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice | Q28513142 | ||
Genomic imprinting: parental influence on the genome | Q29616227 | ||
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum | Q29618151 | ||
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors | Q29619012 | ||
Insulin-promoter-factor 1 is required for pancreas development in mice | Q29619695 | ||
Transcription of the mouse PAC1 receptor gene: cell-specific expression and regulation by Zac1. | Q31062590 | ||
Pax genes and the differentiation of hormone-producing endocrine cells in the pancreas | Q33855370 | ||
Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions. | Q33903904 | ||
A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC. | Q33913119 | ||
Perspective: Postnatal pancreatic beta cell growth | Q33929597 | ||
Regulation of the pancreatic pro-endocrine gene neurogenin3. | Q33945269 | ||
Mouse Zac1, a transcriptional coactivator and repressor for nuclear receptors | Q33962326 | ||
The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function | Q34346667 | ||
Reprogramming of genome function through epigenetic inheritance | Q34426502 | ||
Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function. | Q34427073 | ||
Nutrient-secretion coupling in the pancreatic islet beta-cell: recent advances | Q34560782 | ||
Transient neonatal diabetes and later onset diabetes: a case of inherited insulin resistance | Q34795490 | ||
GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization | Q34997816 | ||
Regulation of pdx-1 gene expression | Q35022138 | ||
Pancreatic cell lineage analyses in mice | Q35080583 | ||
PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance. | Q35159144 | ||
Aetiopathology and genetic basis of neonatal diabetes | Q35285260 | ||
Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion | Q40866515 | ||
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas | Q40867538 | ||
Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2. | Q40878349 | ||
Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system | Q40915252 | ||
Pancreatic development and maturation of the islet B cell. Studies of pluripotent islet cultures | Q41343014 | ||
The beta cell transcription factors and development of the pancreas | Q41496269 | ||
The mouse Zac1 locus: basis for imprinting and comparison with human ZAC. | Q42680409 | ||
Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet | Q43908141 | ||
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development | Q44055107 | ||
Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes. | Q44418710 | ||
A genome-wide scan for type 2 diabetes in African-American families reveals evidence for a locus on chromosome 6q. | Q46661066 | ||
Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites | Q47888790 | ||
Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac. | Q48188005 | ||
A conserved imprinting control region at the HYMAI/ZAC domain is implicated in transient neonatal diabetes mellitus | Q48561080 | ||
Temporal and quantitative correlations between insulin secretion and stably elevated or oscillatory cytoplasmic Ca2+ in mouse pancreatic beta-cells. | Q52237874 | ||
Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model. | Q52348002 | ||
An imprinted locus associated with transient neonatal diabetes mellitus | Q57261281 | ||
Regulatory factor linked to late-onset diabetes? | Q58986438 | ||
Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas | Q59070691 | ||
Genome-Wide Linkage Analysis Assessing Parent-of-Origin Effects in the Inheritance of Type 2 Diabetes and BMI in Pima Indians | Q59150799 | ||
Glucose-stimulated DNA replication of the pancreatic islets during the development of the rat fetus. Effects of nutrients, growth hormone, and triiodothyronine | Q69900042 | ||
Further evidence for an imprinted gene for neonatal diabetes localised to chromosome 6q22-q23 | Q71617593 | ||
Developmental biology of the pancreas | Q71845371 | ||
An imprinted gene(s) for diabetes? | Q72161192 | ||
Congenital absence of insulin cells in a neonate with diabetes mellitus and mutase-deficient methylmalonic acidaemia | Q72216746 | ||
Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter | Q73473642 | ||
Characterization of the methylation-sensitive promoter of the imprinted ZAC gene supports its role in transient neonatal diabetes mellitus | Q73738916 | ||
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1 | Q73777239 | ||
Transient neonatal diabetes: widening the understanding of the etiopathogenesis of diabetes | Q74102330 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | glucose | Q37525 |
glycobiology | Q899224 | ||
transient neonatal diabetes mellitus | Q7834286 | ||
P304 | page(s) | 339-348 | |
P577 | publication date | 2004-08-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM | |
P478 | volume | 114 |
Q37797961 | 6q24 transient neonatal diabetes. |
Q57173336 | Aberrantly expressed genes and miRNAs in human hypopharyngeal squamous cell carcinoma based on RNA‑sequencing analysis |
Q34442748 | BACs as tools for the study of genomic imprinting |
Q37219834 | Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice |
Q55277101 | Chromosome 6q24-related diabetes mellitus. |
Q33603660 | Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts β-cell Function |
Q41885314 | Concurrent course of transient neonatal diabetes with cholestasis and paucity of interlobular bile ducts: a case report. |
Q38108670 | Could lncRNAs contribute to β-cell identity and its loss in Type 2 diabetes? |
Q33740650 | Degree of methylation of ZAC1 (PLAGL1) is associated with prenatal and post-natal growth in healthy infants of the EDEN mother child cohort |
Q38086766 | Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes |
Q37994282 | Diabetes mellitus and the β cell: the last ten years |
Q59198124 | Diabètes sucrés néonatals |
Q51889267 | Differential expression pattern of ZAC in developing mouse and human pancreas. |
Q34342504 | Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues. |
Q46706648 | Early onset diabetes mellitus |
Q41689688 | Epigenetics in formation, function, and failure of the endocrine pancreas |
Q42669985 | Further refinement of the critical minimal genetic region for the imprinting disorder 6q24 transient neonatal diabetes. |
Q37004529 | Genetic and epigenetic defects at the 6q24 imprinted locus in a cohort of 13 patients with transient neonatal diabetes: new hypothesis raised by the finding of a unique case with hemizygotic deletion in the critical region |
Q27865274 | Genetics and pathophysiology of neonatal diabetes mellitus |
Q90319801 | Genome-wide methylomic analysis in individuals with HNF1B intragenic mutation and 17q12 microdeletion |
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Q37696626 | Hypoglycaemia following diabetes remission in patients with 6q24 methylation defects: expanding the clinical phenotype. |
Q26829945 | Imprinted Zac1 in neural stem cells |
Q36874343 | Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood. |
Q92617573 | LncRNA TUG1 ameliorates diabetic nephropathy by inhibiting miR-21 to promote TIMP3-expression |
Q39847763 | Long non-coding RNA ENSMUST00000147869 protects mesangial cells from proliferation and fibrosis induced by diabetic nephropathy |
Q34656513 | Microarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic β cell line MIN6. |
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Q36194882 | Mutations in the Kir6.2 subunit of the KATP channel and permanent neonatal diabetes: new insights and new treatment |
Q46625457 | Neonatal diabetes mellitus |
Q81152665 | Neonatal diabetes mellitus |
Q35742082 | Neonatal diabetes mellitus: a disease linked to multiple mechanisms |
Q34037120 | Neonatal diabetes mellitus: a model for personalized medicine |
Q33343294 | Neonatal diabetes: how research unravelling the genetic puzzle has both widened our understanding of pancreatic development whilst improving children's quality of life |
Q43554623 | Neuropsychological dysfunction and developmental defects associated with genetic changes in infants with neonatal diabetes mellitus: a prospective cohort study [corrected]. |
Q39302029 | Overexpression of ZAC impairs glucose-stimulated insulin translation and secretion in clonal pancreatic beta-cells |
Q37097498 | Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt |
Q56777707 | Pdx1- and Ngn3-Cre-Mediated PLAG1 Expression in the Pancreas Leads to Endocrine Hormone Imbalances That Affect Glucose Metabolism |
Q35665947 | Pericentrin Is Related to Abnormal β-Cell Insulin Secretion through F-Actin Regulation in Mice |
Q48162007 | Permanent neonatal diabetes caused by abnormalities in chromosome 6q24. |
Q33883436 | Regulation of cardiomyocyte Glut4 expression by ZAC1 |
Q52085968 | Resourceful imprinting. |
Q39172425 | Role of DNA methylation in imprinting disorders: an updated review |
Q26795765 | Role of ZAC1 in transient neonatal diabetes mellitus and glucose metabolism |
Q35458473 | Roles of imprinted genes in neural stem cells |
Q57303417 | The diagnosis and management of monogenic diabetes in children and adolescents |
Q34559930 | The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in mice |
Q34426232 | The role of genomic imprinting in biology and disease: an expanding view |
Q35295496 | The role of imprinted genes in fetal growth abnormalities |
Q51992629 | Tissue-specific imprinting of the ZAC/PLAGL1 tumour suppressor gene results from variable utilization of monoallelic and biallelic promoters. |
Q59130141 | Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells |
Q35902835 | Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia |
Q35859435 | Transient Neonatal Diabetes Mellitus followed by recurrent asymptomatic hypoglycaemia: a case report |
Q64968384 | Transient multifocal genomic crisis creating chromothriptic and non-chromothriptic rearrangements in prezygotic testicular germ cells. |
Q39355907 | Transient neonatal diabetes mellitus gene Zac1 impairs insulin secretion in mice through Rasgrf1 |
Q34134807 | Transient neonatal diabetes mellitus type 1. |
Q35852352 | Unlocking the secrets of the pancreatic beta cell: man and mouse provide the key. |
Q24301866 | ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome |
Q42483072 | Zac1 Regulates the Differentiation and Migration of Neocortical Neurons via Pac1. |
Q34412930 | Zac1 is expressed in progenitor/stem cells of the neuroectoderm and mesoderm during embryogenesis: differential phenotype of the Zac1-expressing cells during development |