| scholarly article | Q13442814 |
| P50 | author | Josep Rizo | Q58110018 |
| P2093 | author name string | Hongtao Yu | |
| Tomohiro Matsumoto | |||
| Toshiyuki Habu | |||
| Xuelian Luo | |||
| Guohong Xia | |||
| P2860 | cites work | Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20 | Q22253272 |
| Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint | Q24297170 | ||
| Identification of a MAD2-binding protein, CMT2, and its role in mitosis | Q24321983 | ||
| Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint | Q24534571 | ||
| Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores | Q24534626 | ||
| Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex | Q24548359 | ||
| Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation | Q24550894 | ||
| Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores | Q24555706 | ||
| The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation | Q24601346 | ||
| MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity | Q24648493 | ||
| The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores | Q24651512 | ||
| Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 | Q24670095 | ||
| Mad2 transiently associates with an APC/p55Cdc complex during mitosis | Q24682864 | ||
| Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores | Q24682946 | ||
| The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20 | Q27637433 | ||
| Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells | Q27860926 | ||
| MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p | Q27935794 | ||
| Budding yeast Cdc20: a target of the spindle checkpoint. | Q27936296 | ||
| Regulation of APC-Cdc20 by the spindle checkpoint | Q28216974 | ||
| Direct Binding of CDC20 Protein Family Members Activates the Anaphase-Promoting Complex in Mitosis and G1 | Q28282074 | ||
| Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family | Q28288497 | ||
| Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 | Q28588417 | ||
| MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells | Q28593914 | ||
| The anaphase-promoting complex: proteolysis in mitosis and beyond | Q28610045 | ||
| How cells get the right chromosomes | Q29618857 | ||
| Mitotic forces control a cell-cycle checkpoint | Q29620239 | ||
| Microinjection of Antibody to Mad2 Protein into Mammalian Cells in Mitosis Induces Premature Anaphase | Q30442107 | ||
| Spindle checkpoint requires Mad1-bound and Mad1-free Mad2. | Q33787823 | ||
| The spindle checkpoint, aneuploidy, and cancer | Q33976673 | ||
| Mad2-Independent Inhibition of APCCdc20 by the Mitotic Checkpoint Protein BubR1 | Q34101240 | ||
| Mitotic checkpoints: from yeast to cancer | Q34132846 | ||
| The awesome power of multiple model systems: interpreting the complex nature of spindle checkpoint signaling | Q34682638 | ||
| Segregating sister genomes: the molecular biology of chromosome separation | Q34762863 | ||
| The spindle checkpoint: structural insights into dynamic signalling | Q34931754 | ||
| Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells | Q36293815 | ||
| Fission Yeast Slp1: An Effector of the Mad2-Dependent Spindle Checkpoint | Q39450461 | ||
| Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner | Q39674358 | ||
| The spindle assembly checkpoint | Q41239083 | ||
| The Mad2 spindle checkpoint protein has two distinct natively folded states | Q47943415 | ||
| The mitotic spindle checkpoint | Q77363183 | ||
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3133-43 | |
| P577 | publication date | 2004-08-04 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint | |
| P478 | volume | 23 |
| Q24338298 | A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling |
| Q48577827 | A brief history of error |
| Q42533669 | A new Mad2-interacting domain of Cdc20 is critical for the function of Mad2-Cdc20 complex in the spindle assembly checkpoint |
| Q42956392 | A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism |
| Q37293039 | A quantitative systems view of the spindle assembly checkpoint |
| Q90279283 | APC/C ubiquitin ligase: Functions and mechanisms in tumorigenesis |
| Q24338143 | APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment |
| Q41154841 | APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. |
| Q33777636 | ATP is required for the release of the anaphase-promoting complex/cyclosome from inhibition by the mitotic checkpoint |
| Q39736929 | Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae |
| Q42789905 | Adapt or die: how eukaryotic cells respond to prolonged activation of the spindle assembly checkpoint |
| Q24303505 | Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities |
| Q39022250 | Aneuploidy in Cancer and Aging |
| Q35065131 | BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex |
| Q27933316 | Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest |
| Q54575356 | Cdk1-phosphorylated CUEDC2 promotes spindle checkpoint inactivation and chromosomal instability |
| Q30435929 | Cell division: righting the check |
| Q35694319 | Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC) |
| Q38893872 | Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling |
| Q30300041 | Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint |
| Q38025305 | Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint. |
| Q37525854 | Coordinated regulation of p31(Comet) and Mad2 expression is required for cellular proliferation |
| Q30667509 | Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function. |
| Q35551708 | Defining pathways of spindle checkpoint silencing: functional redundancy between Cdc20 ubiquitination and p31comet |
| Q42063551 | Depletion of p31comet protein promotes sensitivity to antimitotic drugs. |
| Q24307413 | Determinants of conformational dimerization of Mad2 and its inhibition by p31comet |
| Q34082645 | Disassembly of mitotic checkpoint complexes by the joint action of the AAA-ATPase TRIP13 and p31(comet). |
| Q38124517 | Dynamic regulation of ubiquitin-dependent cell cycle control |
| Q35770195 | Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control. |
| Q33772035 | Evaluating putative mechanisms of the mitotic spindle checkpoint |
| Q42252113 | Explaining the oligomerization properties of the spindle assembly checkpoint protein Mad2. |
| Q38346535 | Gene expression profiles of single human mature oocytes in relation to age. |
| Q42207747 | Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation |
| Q36955942 | Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2 |
| Q28472091 | In-silico modeling of the mitotic spindle assembly checkpoint |
| Q27649986 | Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer |
| Q96640282 | Insulin receptor endocytosis in the pathophysiology of insulin resistance |
| Q24310703 | MAD2B, a novel TCF4-binding protein, modulates TCF4-mediated epithelial-mesenchymal transdifferentiation |
| Q47565999 | Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit. |
| Q24684680 | Mad2 overexpression promotes aneuploidy and tumorigenesis in mice |
| Q59086244 | Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13 |
| Q92340719 | Mechanisms for the temporal regulation of substrate ubiquitination by the anaphase-promoting complex/cyclosome |
| Q47158873 | Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing |
| Q38069082 | Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore |
| Q41440478 | Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis |
| Q64096256 | Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling |
| Q36078966 | Mode of interaction of TRIP13 AAA-ATPase with the Mad2-binding protein p31comet and with mitotic checkpoint complexes |
| Q35130703 | Modeling dual pathways for the metazoan spindle assembly checkpoint |
| Q46889398 | Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing |
| Q37939337 | Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint |
| Q37368640 | Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complex |
| Q38260031 | Moving Right Along: How PP1 Helps Clear the Checkpoint |
| Q34026709 | Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling. |
| Q35576429 | Mutual regulation between the spindle checkpoint and APC/C |
| Q29619455 | On the road to cancer: aneuploidy and the mitotic checkpoint |
| Q42715771 | Orderly Inactivation of the Key Checkpoint Protein Mitotic Arrest Deficient 2 (MAD2) during Mitotic Progression |
| Q37281373 | P31comet, a member of the synaptonemal complex, participates in meiotic DSB formation in rice |
| Q38099298 | Panta rhei: the APC/C at steady state |
| Q55099755 | Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison. |
| Q36781122 | Phosphorylation of Xenopus p31(comet) potentiates mitotic checkpoint exit |
| Q34359110 | Phosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition |
| Q39998109 | Phosphorylation regulates the p31Comet-mitotic arrest-deficient 2 (Mad2) interaction to promote spindle assembly checkpoint (SAC) activity |
| Q24315748 | Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint |
| Q37101664 | Protein metamorphosis: the two-state behavior of Mad2. |
| Q54475533 | Purification and assay of Mad2: a two-state inhibitor of anaphase-promoting complex/cyclosome |
| Q33112709 | RED, a Spindle Pole-associated Protein, Is Required for Kinetochore Localization of MAD1, Mitotic Progression, and Activation of the Spindle Assembly Checkpoint |
| Q36149393 | RanGTP aids anaphase entry through Ubr5-mediated protein turnover |
| Q30574064 | Regulation of mitosis and taxane response by Daxx and Rassf1 |
| Q42407469 | Release of Mps1 from kinetochores is crucial for timely anaphase onset. |
| Q37112275 | Reverse the curse--the role of deubiquitination in cell cycle control |
| Q92225902 | Role of Polo-like kinase 1 in the regulation of the action of p31comet in the disassembly of mitotic checkpoint complexes |
| Q35991476 | Role of phosphorylation of Cdc20 in p31 comet -stimulated disassembly of the mitotic checkpoint complex |
| Q36967810 | Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly |
| Q38331468 | Sharpening the anaphase switch. |
| Q24306351 | Shugoshin is a Mad1/Cdc20-like interactor of Mad2 |
| Q37271332 | Smurf2 as a novel mitotic regulator: From the spindle assembly checkpoint to tumorigenesis |
| Q30414432 | Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling |
| Q28081253 | Spatiotemporal regulation of the anaphase-promoting complex in mitosis |
| Q59800358 | Spindle Checkpoint Regulators in Insulin Signaling |
| Q41867463 | Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors. |
| Q24682934 | Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore |
| Q41849720 | Staging a recovery from mitotic arrest: Unusual ways of Cdk1 |
| Q36867692 | State of the APC/C: organization, function, and structure |
| Q24683708 | Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model |
| Q27678130 | Structure of the mitotic checkpoint complex |
| Q34316984 | Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living <em>Drosophila</em> Syncytial Embryos |
| Q57810920 | TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC |
| Q35616366 | TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching |
| Q27309241 | TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response |
| Q46288094 | Taming the Beast: Control of APC/C(Cdc20)-Dependent Destruction. |
| Q46175396 | The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding |
| Q27932569 | The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation. |
| Q38707137 | The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation |
| Q35003017 | The Cdc20-binding Phe box of the spindle checkpoint protein BubR1 maintains the mitotic checkpoint complex during mitosis |
| Q37063126 | The Composition, Functions, and Regulation of the Budding Yeast Kinetochore |
| Q24300755 | The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint |
| Q34625506 | The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins |
| Q34264016 | The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregation |
| Q33399870 | The influence of catalysis on mad2 activation dynamics |
| Q40446144 | The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint |
| Q41146841 | The mitotic checkpoint complex (MCC): looking back and forth after 15 years |
| Q26776388 | The multifaceted roles of the HORMA domain in cellular signaling |
| Q37369189 | The multiple layers of ubiquitin-dependent cell cycle control. |
| Q26852465 | The spindle checkpoint and chromosome segregation in meiosis |
| Q27860766 | The spindle-assembly checkpoint in space and time |
| Q42928048 | The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC. |
| Q35498796 | Topoisomerase IIα in chromosome instability and personalized cancer therapy. |
| Q36747293 | USP7 and Daxx regulate mitosis progression and taxane sensitivity by affecting stability of Aurora-A kinase |
| Q41792415 | Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation |
| Q47105112 | Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C). |
| Q35551712 | p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment |
| Q42911667 | p31(comet) inactivates the chemically induced Mad2-dependent spindle assembly checkpoint and leads to resistance to anti-mitotic drugs |
| Q34602368 | p31comet Promotes disassembly of the mitotic checkpoint complex in an ATP-dependent process |
| Q24300775 | p31comet blocks Mad2 activation through structural mimicry |
| Q36257698 | p31comet-Induced Cell Death Is Mediated by Binding and Inactivation of Mad2. |
| Q35576470 | p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit. |
Search more.