Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine

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Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI112442
P8608Fatcat IDrelease_lhinmnhxxzfxpiezhugmvfkthm
P953full work available at URLhttps://www.jci.org/articles/view/112442
P243OCLC control number115268931
P3181OpenCitations bibliographic resource ID2605917
P932PMC publication ID424498
P698PubMed publication ID3514679

P2093author name stringG Starkebaum
J M Harlan
P2860cites workHomocystinemia. Vascular injury and arterial thrombosisQ68342307
D-Penicillamine: analysis of the mechanism of copper-catalyzed hydrogen peroxide generationQ70081325
Homocysteine in the plasma of renal transplant recipients: effects of cofactors for methionine metabolismQ70188404
The participation of hydroperoxides and oxygen radicals in the control of prostaglandin synthesisQ70434451
Endothelial cell dysfunction in homocystinuriaQ70455278
Moderate homocysteinemia--a possible risk factor for arteriosclerotic cerebrovascular diseaseQ70690494
Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboonsQ71097689
Accumulation of sulphur-containing amino acids including cysteine-homocysteine in patients on maintenance haemodialysisQ71236870
Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injuryQ71282008
Increased plasma copper in patients with homocystinuria due to cystathionine beta-synthase deficiencyQ71662220
Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagentQ28248838
Sulphur containing amino acids in chronic renal failure with particular reference to homocystine and cysteine-homocysteine mixed disulphideQ28319264
Generation of superoxide free radical during the autoxidation of thiolsQ34204226
Atherosclerosis and the arterial smooth muscle cell: Proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosisQ34207431
H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factorsQ34478055
Presence of lipid hydroperoxide in human plasmaQ34532273
Resistance of human tumor cells in vitro to oxidative cytolysisQ34541025
Effect of hydrogen peroxide on prostaglandin production and cellular integrity in cultured porcine aortic endothelial cellsQ34543767
Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in cultureQ34620804
Unique efficiency of methionine metabolism in premenopausal women may protect against vascular disease in the reproductive yearsQ35208030
Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesisQ35904374
The detection of cysteine‐homocysteine mixed disulphide in plasma of normal fasting manQ39623108
Bovine superoxide dismutase and copper ions potentiate the bactericidal effect of autoxidizing cysteineQ40078118
The pathogenesis of atherosclerosis (second of two parts)Q40547842
Neutrophil-mediated endothelial injury in vitro mechanisms of cell detachmentQ40684511
Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxideQ40925470
Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.Q41576959
Production of arteriosclerosis by homocysteinemiaQ42648820
Mutagenicity of Glutathione and Cysteine in the Ames TestQ50211434
The reaction of cysteine with ceruloplasmin copperQ50921936
Cysteine—Homocysteine Mixed Disulphide: Differing Plasma Concentrations in Normal Men and WomenQ51661954
The copper catalyzed oxidation of cysteine to cystine.Q54424767
The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytesQ60786799
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcopperQ753
endotheliumQ111140
P304page(s)1370-6
P577publication date1986-01-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleEndothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine
P478volume77

Reverse relations

cites work (P2860)
Q24302132A novel homocysteine-responsive gene, smap8, modulates mitogenesis in rat vascular smooth muscle cells
Q28068779A review about biomarkers for the investigation of vascular function and impairment in diabetes mellitus
Q35603932ADMA and oxidative stress
Q85094853Acute Liver Failure and Reversible Leukoencephalopthy in a Pediatric Patient With Homocystinuria
Q28354189Acute hyperhomocysteinaemia affects pulse pressure but not microvascular vasodilator function
Q43069827Adult rats are more sensitive to the vascular effects induced by hyperhomocysteinemia than young rats
Q35824103Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
Q77124479Age and cystathionine beta-synthase activity in cultured fibroblasts from patients with arterial and venous vascular disease
Q44524401Alteration in the redox state of plasma in heart-transplant patients with moderate hyperhomocysteinemia
Q54088301Antioxidants, but not B-group vitamins increase the resistance of low-density lipoprotein to oxidation: a randomized, factorial design, placebo-controlled trial.
Q42714111Arterial endothelial barrier dysfunction: actions of homocysteine and the hypoxanthine-xanthine oxidase free radical generating system
Q41486934Assessment of a possible link between hyperhomocysteinemia and hyperuricemia
Q58180355Association between elevated plasma total homocysteine and increased common carotid artery wall thickness
Q38194052Association of MTHFR C677T polymorphism and risk of cerebrovascular disease in Chinese population: an updated meta-analysis
Q41099743Associations between Homocysteine, Folic Acid, Vitamin B12 and Alzheimer's Disease: Insights from Meta-Analyses
Q44460931Atherosclerosis and uremia: signifance of non-traditional risk factors
Q36647334Atherosclerotic vascular disease: will folate or gene therapy be useful?
Q48944746Beneficial effects of folic acid on enhancement of memory and antioxidant status in aged rat brain.
Q40693454Bioactivation of thiols by one-electron oxidation
Q34107196Biochemical evidence for a link between elevated levels of homocysteine and lipid peroxidation in vivo
Q44945420Biphasic effect of hydrogen peroxide on skeletal muscle arteriolar tone via activation of endothelial and smooth muscle signaling pathways
Q34107404Blood levels of homocysteine and atherosclerotic vascular disease
Q44487554Brain energy metabolism is compromised by the metabolites accumulating in homocystinuria
Q37434251Can APOE and MTHFR polymorphisms have an influence on the severity of cardiovascular manifestations in Italian Pseudoxanthoma elasticum affected patients?
Q44407404Changes in markers of vascular injury in response to transient hyperhomocysteinemia
Q54097159Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: antioxidant implications.
Q42159238Characterization of the stress-inducing effects of homocysteine
Q56832765Circulating cell adhesion molecules and endothelial markers before and after transluminal angioplasty in peripheral arterial occlusive disease
Q42068706Converging evidence of mitochondrial dysfunction in a yeast model of homocysteine metabolism imbalance
Q44426592Copper induces type II nitric oxide synthase in vivo
Q89009865Copper transporters and copper chaperones: roles in cardiovascular physiology and disease
Q40737536Copper-induced vascular endothelial growth factor expression and wound healing
Q35037752Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage.
Q73189643Correlation of homocytsteine levels with the extent of coronary atherosclerosis in patients with low cardiovascular risk profiles
Q92186536Cu/Zn-superoxide dismutase and wild-type like fALS SOD1 mutants produce cytotoxic quantities of H2O2 via cysteine-dependent redox short-circuit
Q41208237Cyclin A transcriptional suppression is the major mechanism mediating homocysteine-induced endothelial cell growth inhibition
Q42400895Cystathionine beta synthase modulates senescence of human endothelial cells.
Q44426855DNA damage by ethylbenzenehydroperoxide formed from carcinogenic ethylbenzene by sunlight irradiation
Q37352044Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis
Q42577216Defective responses to oxidative stress in protein l-isoaspartyl repair-deficient Caenorhabditis elegans
Q55064708Detection and investigation of the molecular nature of low-molecular-mass copper ions in isolated rheumatoid knee-joint synovial fluid.
Q31967263Differences between cysteine and homocysteine in the induction of deoxyribose degradation and DNA damage
Q45903164Differential expression of lipid peroxidation and total antioxidant status in Indian patients with cardiovascular and cerebrovascular disease.
Q46802337Distribution of androstenedione and its effects on total free fatty acids in pregnant rats
Q44373903Effect of a methionine-supplemented diet on the blood pressure of Wistar-Kyoto and spontaneously hypertensive rats
Q33834502Effect of folic Acid on hematological changes in methionine-induced hyperhomocysteinemia in rats
Q74649129Effect of homocysteine and cholesterol in raising plasma homocysteine, cholesterol and triglyceride levels
Q42520120Effect of homocysteine on arachidonic acid release in human platelets
Q42514335Effect of homocysteine on nitric oxide production in coronary microvascular endothelial cells
Q41961021Effect of prolonged incubation with copper on endothelium-dependent relaxation in rat isolated aorta.
Q73310526Effect of short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-methionine load hyperhomocysteinemia
Q43687601Effect of vitamin E on resistance vessel endothelial dysfunction induced by methionine
Q45743581Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: the role of different gasotransmitters.
Q44264664Effects of certain micronutrients and melatonin on plasma lipid, lipid peroxidation, and homocysteine levels in rats.
Q46973576Effects of estrogen and estrogen-progestogen therapy on homocysteine levels and their correlation with carotid vascular resistance
Q40931043Effects of folate deficiency on embryonic development
Q54325558Effects of folic acid on the development and oxidative stress of mouse embryos exposed to heat stress.
Q73289615Effects of homocysteine on the binding of extracellular-superoxide dismutase to the endothelial cell surface
Q44457155Effects of long-term administration of methionine on vascular endothelium in rabbits
Q40028542Effects of serum homocysteine and adiponectin levels on platelet aggregation in untreated patients with essential hypertension.
Q44474830Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice
Q39317514Elevated serum homocysteine level as an independent risk factor for erectile dysfunction: a prospective pilot case-control study
Q35055199Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia
Q28591362Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia
Q45135207Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA.
Q90150796Evaluation of homocystein and asymmetric dimethyl arginine levels in patients with coronary slow flow phenomenon
Q31941042Evidence against oxidative stress as mechanism of endothelial dysfunction in methionine loading model.
Q40513939Evidence for a protective (synergistic?) effect of B-vitamins and omega-3 fatty acids on cardiovascular diseases
Q63197184Experimental evidence of oxidative stress in plasma of homocystinuric patients: A possible role for homocysteine
Q43784576Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells
Q36351455Folates in Plants: Research Advances and Progress in Crop Biofortification
Q51559556Folic acid improves arterial endothelial function in adults with hyperhomocystinemia.
Q35675495Folic acid supplementation reduces oxidative stress and hepatic toxicity in rats treated chronically with ethanol
Q58402090Folic acid, pyridoxine, cobalamin, and homocysteine and their relationship to cardiovascular disease in end-stage renal disease
Q33622289Fracture is additionally attributed to hyperhomocysteinemia in men and premenopausal women with type 2 diabetes
Q34722600Free radicals, diabetes and endothelial dysfunction.
Q42391435Genes, greens, and homocysteine
Q36265315Genetic determinants of hyperhomocysteinemia in atherosclerosis
Q74342695High prevalence of hyperhomocysteinemia due to marginal deficiency of cobalamin or folate in chronic myeloproliferative disorders
Q72049325Higher Plasma Homocyst(e)ine and Increased Susceptibility to Adverse Effects of Low Folate in Early Familial Coronary Artery Disease
Q51760865Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.
Q53793755Homocysteine accelerates endothelial cell senescence.
Q42523086Homocysteine activates platelets in vitro
Q35582716Homocysteine and Essential Hypertension
Q35027762Homocysteine and arterial disease. Experimental mechanisms
Q34455031Homocysteine and cardiovascular disease in diabetes mellitus
Q34641564Homocysteine and cardiovascular disease: current evidence and future prospects
Q44485364Homocysteine and hemostatic disorder as a risk factor for myocardial infarction at a young age.
Q38948319Homocysteine and hydrogen sulfide in epigenetic, metabolic and microbiota related renovascular hypertension
Q37271062Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: a potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism
Q47731955Homocysteine and oxidative modification of plasma proteins.
Q58297326Homocysteine and total antioxidant status in acute myocardial infarction patients among Tamil population
Q40911244Homocysteine and vascular dysfunction.
Q33969606Homocysteine as a risk factor for development of microalbuminuria in type 2 diabetes
Q43739303Homocysteine as a risk factor for nephropathy and retinopathy in Type 2 diabetes.
Q43812254Homocysteine attenuates endothelial haem oxygenase-1 induction by nitric oxide (NO) and hypoxia
Q24337464Homocysteine contribution to DNA damage in cystathionine β-synthase-deficient patients
Q40707186Homocysteine decreases endothelin-1 expression by interfering with the AP-1 signaling pathway
Q40941876Homocysteine decreases endothelin-1 production by cultured human endothelial cells.
Q74339183Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
Q42238968Homocysteine in dogs with systemic inflammatory response syndrome.
Q38223130Homocysteine in renovascular complications: hydrogen sulfide is a modulator and plausible anaerobic ATP generator
Q43912991Homocysteine increases monocyte and T-cell adhesion to human aortic endothelial cells
Q42339328Homocysteine inhibits adipogenesis in 3T3-L1 preadipocytes
Q43713584Homocysteine inhibits tumor necrosis factor-induced activation of endothelium via modulation of nuclear factor-kappa b activity
Q39255149Homocysteine is linked to macular edema in type 2 diabetes
Q44123489Homocysteine is the only plasma thiol associated with carotid artery remodeling
Q46770313Homocysteine levels are associated with MTHFR A1298C polymorphism in Indian population
Q44533433Homocysteine oxidation and apoptosis: a potential cause of cleft palate
Q32134706Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways
Q35538219Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc.
Q44219160Homocysteine promotes the LDL oxidase activity of ceruloplasmin
Q73385445Homocysteine provokes leukocyte-endothelium interaction by downregulation of nitric oxide
Q40839063Homocysteine stimulates nuclear factor kappaB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells: a possible role for protein kinase C.
Q28367240Homocysteine stimulates the expression of monocyte chemoattractant protein-1 receptor (CCR2) in human monocytes: possible involvement of oxygen free radicals
Q34066620Homocysteine to hydrogen sulfide or hypertension
Q33855736Homocysteine toxicity in Escherichia coli is caused by a perturbation of branched-chain amino acid biosynthesis
Q37126086Homocysteine toxicity in connective tissue: theories, old and new.
Q34352230Homocysteine, Another Risk Factor for Alzheimer Disease, Impairs Apolipoprotein E3 Function
Q37231486Homocysteine, MTHFR gene polymorphisms, and cardio-cerebrovascular risk
Q40304955Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells
Q39288512Homocysteine, an additional factor, is linked to osteoporosis in postmenopausal women with type 2 diabetes
Q41508423Homocysteine, oxidative stress, and vascular disease
Q41763764Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast.
Q40996776Homocysteine-dependent alterations in mitochondrial gene expression, function and structure. Homocysteine and H2O2 act synergistically to enhance mitochondrial damage
Q44497496Homocysteine-induced brain lipid peroxidation: effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition.
Q28365886Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
Q38293097Homocysteine-induced extracellular superoxide dismutase and its epigenetic mechanisms in monocytes
Q35612116Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor
Q33732664Homocysteine.
Q36410590Homocysteine: role and implications in atherosclerosis
Q38460537Homocysteinemia as a risk factor for atherosclerosis: a review
Q36680974Homocystinuria: what about mild hyperhomocysteinaemia?
Q35594829Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion
Q43978616Hyperhomocyst(e)inemia and hemostatic factors: the atherosclerosis risk in communities study
Q44049645Hyperhomocyst(e)inemia induces accelerated transplant vascular sclerosis in syngeneic and allogeneic rat cardiac transplants
Q35008507Hyperhomocyst(e)inemia: a risk factor for cerebrovascular disease.
Q34435609Hyperhomocysteinaemia and associated disease
Q74578253Hyperhomocysteinaemia and vascular disease
Q46663117Hyperhomocysteinaemia induced by dietary folate restriction causes kidney oxidative stress in rats
Q50995714Hyperhomocysteinaemia is a risk factor for vein graft stenosis.
Q36669874Hyperhomocysteinaemia; with reference to its neuroradiological aspects
Q36740468Hyperhomocysteinemia and cardiovascular risk in postmenopausal women: the role of folate supplementation.
Q35209853Hyperhomocysteinemia and its role in the development of atherosclerosis
Q57811732Hyperhomocysteinemia and the response to vitamin supplementation
Q37812131Hyperhomocysteinemia and thrombophilia
Q77621762Hyperhomocysteinemia and thrombosis
Q33797998Hyperhomocysteinemia as a Metabolic Risk Factor for Glucose Intolerance Among High-Risk Groups of Chinese Adults
Q73627437Hyperhomocysteinemia following oral methionine load is associated with increased lipid peroxidation
Q44887004Hyperhomocysteinemia in patients with diabetes mellitus with and without diabetic retinopathy
Q43297450Hyperhomocysteinemia induced by feeding rats diets rich in DL-homocysteine thiolactone promotes alterations on carotid reactivity independent of arterial structure.
Q34222836Identification and characterization of two isoenzymes of methionine gamma-lyase from Entamoeba histolytica: a key enzyme of sulfur-amino acid degradation in an anaerobic parasitic protist that lacks forward and reverse trans-sulfuration pathways
Q34249956Impaired homocysteine metabolism and atherothrombotic disease
Q35542924Implications of Oxidative Stress and Homocysteine in the Pathophysiology of Essential Hypertension
Q77370130Improvement of coronary artery disease in a patient with hyperhomocysteinemia: report of a case
Q53834913Increased Plasma Homocysteine Level is Associated with Executive Dysfunction in Type 2 Diabetic Patients with Mild Cognitive Impairment.
Q42197124Increased hepatic lipid peroxidation with methionine toxicity in the rat.
Q71699966Increased lipid peroxidation and antioxidant activity in methionine-induced hepatitis in rabbits
Q87957224Influence of hyperhomocysteinemia on left ventricular diastolic function in Chinese patients with hypertension
Q35600441Influence of hyperhomocysteinemia on the cellular redox state--impact on homocysteine-induced endothelial dysfunction
Q34213851Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
Q37724635Integration of ER stress, oxidative stress and the inflammatory response in health and disease
Q35600437Interactions of homocysteine, nitric oxide, folate and radicals in the progressively damaged endothelium
Q24188051Interventions for lowering plasma homocysteine levels in kidney transplant recipients
Q43833278Intraperitoneal infusion of homocysteine increases intimal hyperplasia in balloon-injured rat carotid arteries
Q41951247Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta
Q43839970Is homocysteine a pro-oxidant?
Q43907969Leukocytes extravasation in acute homocysteinemic rats
Q67560177Lipid peroxidation in homocysteinaemia
Q51548088Lipid peroxidation induced in vivo by hyperhomocysteinaemia in pigs.
Q33790567MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate
Q46772983MTHFR C677T polymorphism associates with unexplained infertile male factors
Q36133409MTHFR C677T polymorphism is associated with hyperlipidemia in women with polycystic ovary syndrome
Q46949321MTHFR C677T polymorphism, GSTM1 deletion and male infertility: a possible suggestion of a gene-gene interaction?
Q42137731Matrix metalloproteinase-9 in homocysteine-induced intestinal microvascular endothelial paracellular and transcellular permeability
Q80821757Mechanism of UVA-dependent DNA damage induced by an antitumor drug dacarbazine in relation to its photogenotoxicity
Q39599160Mechanism of constrictive vascular remodeling by homocysteine: role of PPAR.
Q39957446Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells
Q41281849Metabolism of homocysteine, its relation to the other cellular thiols and its mechanism of cell damage in a cell culture line (human histiocytic cell line U-937)
Q46495530Methionine, folic acid and vitamin B12 in growing-finishing pigs: impact on growth performance and meat quality
Q54361317Methylenetetrahydrofolate reductase C677T polymorphism is not associated with male infertility in a South Indian population.
Q28506932Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia
Q44413402Mild hyperhomocysteinemia and fibrinolytic factors in patients with history of venous thromboembolism.
Q25257578Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies
Q33819518Moderate hyperhomocysteinemia and cardiovascular disease
Q37274442Molecular mechanisms of adaptation to folate deficiency
Q50940035Mutation (677 C to T) in the methylenetetrahydrofolate reductase gene aggravates hyperhomocysteinemia in hemodialysis patients.
Q40923118New approaches to the prevention of atherosclerosis
Q41701273New risk factors for coronary heart disease in Asia
Q40113992No evidence for prooxidative effects of homocysteine in vascular endothelial cells
Q40693186Nutrition, endothelial cell metabolism, and atherosclerosis
Q34006724Nutritional aspects and possible pathological mechanisms of hyperhomocysteinaemia: an independent risk factor for vascular disease.
Q34086042Occlusive vascular diseases in oral contraceptive users. Epidemiology, pathology and mechanisms
Q41679390Oral administration of homocysteine leads to increased plasma triglycerides and homocysteic acid — additional mechanisms in homocysteine induced endothelial damage?
Q33947823Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction
Q44281727Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia
Q44133768Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation
Q37299480Pharmacogenetics of the neurodevelopmental impact of anticancer chemotherapy
Q64260769Plasma Free Homocysteine Levels in Children with Idiopathic Nephrotic Syndrome
Q46415528Plasma homocysteine and total thiol content in patients with exudative age-related macular degeneration
Q54969525Plasma homocysteine is associated with increased oxidative stress and antioxidant enzyme activity in welders.
Q36449909Plasma homocysteine level and its genotypes as a risk factor for coronary artery disease in patients undergoing coronary angiography
Q37356525Predictive role of C677T MTHFR polymorphism in variable efficacy of photodynamic therapy for neovascular age-related macular degeneration.
Q44913163Predictive value of plasma asymmetric dimethylarginine, homocysteine, and high-sensitive CRP levels in occult coronary artery disease: A multidetector-row computed tomography study
Q34645884Prenatal infectious and nutritional factors and risk of adult schizophrenia
Q42007616Protective effect of hydrogen sulfide on balloon injury-induced neointima hyperplasia in rat carotid arteries
Q41054019Protein binding of homocysteine and other thiols in HeLa cell cultures after addition of homocysteine and copper ions
Q31834254Protein tyrosine phosphatase-dependent proteolysis of focal adhesion complexes in endothelial cell apoptosis
Q41521475Putative mechanisms for vascular damage by homocysteine
Q54366789Quantitative proteomic profiling of the Escherichia coli response to metallic copper surfaces.
Q37828680Reactive oxygen species as mediators of signal transduction in cardiovascular disease
Q44628122Red wine prevents homocysteine-induced endothelial dysfunction in porcine coronary arteries
Q44355803Reduction in plasma total homocysteine through increasing folate intake in healthy individuals is not associated with changes in measures of antioxidant activity or oxidant damage
Q21146652Relationship between homocysteine level and diabetic retinopathy: a systematic review and meta-analysis
Q43761093Relative roles of albumin and ceruloplasmin in the formation of homocystine, homocysteine-cysteine-mixed disulfide, and cystine in circulation
Q44683752Restenosis in Intervened Coronaries with Hyperhomocysteinemia (RICH).
Q37276483Risk factors for coronary artery sclerosis in patients with diabetes.
Q35831223Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease.
Q35090352Role of nitric oxide in matrix remodeling in diabetes and heart failure
Q40460088S-Nitrosothiols and the Bioregulatory Actions of Nitrogen Oxides Through Reactions with Thiol Groups
Q44019190S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase
Q39741317Salidroside improves homocysteine-induced endothelial dysfunction by reducing oxidative stress
Q50192080Selenoproteins and cardiovascular stress
Q50859058Serum folate and risk for coronary heart disease: results from a cohort of US adults.
Q84790241Stereospecific in vitro embryotoxicity of l-homocysteine in pre- and post-implantation rodent embryos
Q73556126Stimulation of endothelial nitric oxide production by homocyst(e)ine
Q44578841Stimulatory effect of homocysteine on interleukin-8 expression in human endothelial cells
Q73209033Stroke prevention
Q48427488Sudden death of an 18-year-old man with homocystinuria and intracranial inflammatory pseudotumor (IPT).
Q92008457Supraphysiologic-dose anabolic-androgenic steroid use: A risk factor for dementia?
Q44221895Sustained increases of plasma homocysteine, copper, and serum ceruloplasmin after coronary artery bypass grafting
Q30927502TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia
Q90420713The Impact of Uremic Toxins on Cerebrovascular and Cognitive Disorders
Q89553066The Link between Homocysteine and Omega-3 Polyunsaturated Fatty Acid: Critical Appraisal and Future Directions
Q90494329The association between homocysteine and ischemic stroke subtypes in Chinese: A meta-analysis
Q46484349The association of endothelin-1 with markers of oxidative stress in a biethnic South African cohort: the SABPA study
Q41083459The cell-damaging effects of low amounts of homocysteine and copper ions in human cell line cultures are caused by oxidative stress
Q78115598The effect of cyst(e)ine on the auto-oxidation of homocysteine
Q24800878The effect on endothelial function of vitamin C during methionine induced hyperhomocysteinaemia
Q89220460The effects of L-cysteine and N-acetyl-L-cysteine on homocysteine metabolism and haemostatic markers, and on cardiac and aortic histology in subchronically methionine-treated Wistar male rats
Q41103765The effects of homocysteine and copper ions on the concentration and redox status of thiols in cell line cultures
Q44615958The effects of hydrogen peroxide promoted by homocysteine and inherited catalase deficiency on human hypocatalasemic patients
Q28349035The effects of oral methionine and homocysteine on endothelial function
Q41486362The effects of oral vitamin supplementation on cardiovascular risk factors
Q68015552The prevalence of homocysteinemia and hypercholesterolemia in angiographically defined coronary heart disease
Q43687631The relation between plasma cysteine, plasma homocysteine and coronary atherosclerosis
Q37351584The relation of markers of inflammation and endothelial dysfunction to the prevalence and progression of diabetic retinopathy: Wisconsin epidemiologic study of diabetic retinopathy
Q41099877The role of free radicals as mediators of endothelial cell injury in hyperhomocysteinemia
Q43792229Thiol oxidase activity of copper, zinc superoxide dismutase
Q33785883Total homocysteine and cardiovascular disease
Q44041076Upregulation of smooth muscle cell collagen production by homocysteine-insight into the pathogenesis of homocystinuria
Q34395823Vascular dysfunction in hyperhomocyst(e)inemia. Implications for atherothrombotic disease
Q37356860Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia
Q44014722Vascular endothelial dysfunction associated with elevated serum homocysteine levels in rat adjuvant arthritis: effect of vitamin E administration
Q55110135Vegetarian Diet and Cardiometabolic Risk among Asian Indians in the United States.
Q52937866Vein graft disease in a knockout mouse model of hyperhomocysteinaemia.
Q43734672Vitamin C prevents radiation-induced endothelium-dependent vasomotor dysfunction and de-endothelialization by inhibiting oxidative damage in the rat.
Q42843095Vitamin E supplementation in chemical colorectal carcinogenesis: a two-edged knife
Q46809067Waist-to-hip ratio correlates with homocysteine levels in male patients with coronary artery disease
Q74243285[Congenital errors of metabolism: cause of oxidative stress?]

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