Homocysteine provokes leukocyte-endothelium interaction by downregulation of nitric oxide

scientific article published on 01 December 1999

Homocysteine provokes leukocyte-endothelium interaction by downregulation of nitric oxide is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0306-3623(99)00045-2
P698PubMed publication ID10647774

P50authorRosario ScaliaQ55590276
P2093author name stringA M Lefer
D Pruefer
P2860cites workEndothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteineQ24563588
GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodiesQ24621927
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineQ29547539
Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversityQ29617967
Inflammatory roles of P-selectinQ34169805
Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endotheliumQ35585847
In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injuryQ35610891
Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometryQ35809715
Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogenQ35824103
Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophilsQ36529236
Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophilsQ36532906
An optical doppler intravital velocimeterQ36624572
Nitric oxide: an endogenous modulator of leukocyte adhesionQ37519420
Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivoQ37583902
Tissue destruction by neutrophilsQ38264463
Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidaseQ40512506
Cytoprotective function of nitric oxide: inactivation of superoxide radicals produced by human leukocytesQ41131860
The role of nitric oxide and cell adhesion molecules on the microcirculation in ischaemia-reperfusionQ41208180
Effects of homocysteine on acetylcholine- and adenosine-induced vasodilatation of pancreatic vascular bed in ratsQ42027675
Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat.Q42105602
The oxidant stress of hyperhomocyst(e)inemiaQ42357039
Direct measurement of nitric oxide release from vascular endothelial cellsQ42525514
Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in plateletsQ42849786
Harvesting the noncirculating pool of polymorphonuclear leukocytes in rats by hetastarch exchange transfusion (HET): yield and functional assessmentQ46172411
Antineutrophil and myocardial protecting actions of a novel nitric oxide donor after acute myocardial ischemia and reperfusion of dogs.Q54040785
Lack of endothelium-dependent relaxation in coronary resistance arteries of cholesterol-fed rabbits.Q54357875
A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular DiseaseQ57268055
Hyperhomocysteinemia: an independent risk factor for vascular diseaseQ70131136
Continuous monitoring of nitric oxide release from human umbilical vein endothelial cellsQ70764147
Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injuryQ71282008
Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculationQ71650202
Time course of coronary vascular endothelial adhesion molecule expression during reperfusion of the ischemic feline myocardiumQ71669842
Can Lowering Homocysteine Levels Reduce Cardiovascular Risk?Q72007689
Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats In vivoQ74583474
P433issue6
P304page(s)487-498
P577publication date1999-12-01
P1433published inGeneral PharmacologyQ27710984
P1476titleHomocysteine provokes leukocyte-endothelium interaction by downregulation of nitric oxide
P478volume33

Reverse relations

cites work (P2860)
Q47434534Attenuation of homocysteine-induced endothelial dysfunction by exercise training
Q28366560Cyclic AMP elevating agents and nitric oxide modulate angiotensin II-induced leukocyte-endothelial cell interactions in vivo
Q33418497Effects of chronic and acute consumption of fruit- and vegetable-puree-based drinks on vasodilation, risk factors for CVD and the response as a result of the eNOS G298T polymorphism
Q44247268Elevated homocysteine serum level is associated with low enrichment of homocysteine in coronary arteries of patients with coronary artery disease
Q42741965Elevated levels of homocysteine compromise blood-brain barrier integrity in mice
Q37230439High-dose folic acid supplementation effects on endothelial function and blood pressure in hypertensive patients: a meta-analysis of randomized controlled clinical trials
Q35027762Homocysteine and arterial disease. Experimental mechanisms
Q34641564Homocysteine and cardiovascular disease: current evidence and future prospects
Q29347008Homocysteine enhances transmigration of rat monocytes through a brain capillary endothelial cell monolayer via ICAM-1
Q41709585Homocysteine-induced peripheral microcirculation dysfunction in zebrafish and its attenuation by L-arginine
Q35556275Hyperhomocysteinemia in heart transplantation: from bench to bedside
Q42366660Immunological consequences of ageing microvascular hemodynamic changes in view of cancer development and treatment
Q37255301Increased endothelin-1 reactivity and endothelial dysfunction in carotid arteries from rats with hyperhomocysteinemia.
Q43907969Leukocytes extravasation in acute homocysteinemic rats
Q28346544NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?
Q40113992No evidence for prooxidative effects of homocysteine in vascular endothelial cells
Q42945396The Jeremiah Metzger Lecture. Hypercoagulable states: challenges and opportunities.

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